GREMLIN Database
Q97ZA9 - Formate hydrogenlyase subunit 3 (HycC)
UniProt: Q97ZA9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 621 (533)
Sequences: 7995 (4987)
Seq/√Len: 216.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
85_N250_K4.2621.00
189_N192_Y3.9731.00
129_I142_G3.7651.00
187_T192_Y3.7241.00
92_S128_T3.3161.00
512_S516_Y3.3001.00
136_Y251_I3.2731.00
48_L100_I3.2051.00
155_G164_P2.9821.00
500_S503_Y2.9671.00
92_S132_N2.8731.00
510_A514_V2.8711.00
213_M272_F2.8051.00
291_L346_S2.7861.00
304_V415_I2.7721.00
368_T430_I2.7021.00
514_V518_A2.6521.00
367_L429_Y2.5731.00
500_S510_A2.5511.00
341_G370_L2.5371.00
157_T227_T2.4701.00
166_V223_I2.4531.00
270_G307_S2.4361.00
47_T50_P2.4321.00
510_A516_Y2.3841.00
503_Y507_L2.3691.00
372_S377_L2.3621.00
445_K449_Y2.3451.00
52_L56_I2.3021.00
348_L443_L2.2911.00
248_I303_L2.2811.00
371_A426_L2.2651.00
108_E444_S2.2521.00
538_E543_F2.2261.00
331_Y385_A2.2051.00
133_S138_L2.1981.00
334_A381_I2.1781.00
184_I198_P2.1741.00
95_S131_L2.1521.00
516_Y520_G2.1351.00
282_Y424_A2.1291.00
200_I204_F2.1151.00
266_I307_S2.1051.00
177_L204_F2.0881.00
536_E540_Y2.0621.00
498_G508_L2.0501.00
208_I215_F2.0351.00
50_P56_I2.0291.00
351_K441_E2.0251.00
306_L328_V2.0161.00
181_G205_G1.9891.00
50_P53_I1.9411.00
160_N227_T1.9291.00
390_L419_E1.9281.00
366_G452_L1.9141.00
203_T262_F1.9071.00
498_G501_P1.8951.00
241_T295_T1.8681.00
249_L306_L1.8641.00
513_I517_L1.8531.00
207_I269_I1.8521.00
352_Q363_I1.8481.00
279_L543_F1.8451.00
146_M240_M1.8431.00
248_I255_T1.8311.00
371_A430_I1.8271.00
283_V539_E1.8051.00
543_F548_N1.7991.00
94_I336_S1.7951.00
330_L385_A1.7591.00
58_S62_K1.7581.00
51_F97_S1.7561.00
51_F55_I1.7501.00
157_T160_N1.7461.00
56_I59_I1.7201.00
510_A518_A1.7081.00
53_I59_I1.7001.00
537_K541_T1.6921.00
503_Y510_A1.6741.00
274_I418_G1.6731.00
47_T61_N1.6671.00
99_W124_I1.6671.00
271_A414_I1.6641.00
158_A162_R1.6391.00
47_T51_F1.6301.00
100_I104_I1.6271.00
43_T47_T1.6171.00
409_I413_A1.6171.00
598_S603_Y1.6121.00
353_S356_Y1.5971.00
510_A515_S1.5941.00
83_E86_G1.5921.00
49_P52_L1.5831.00
541_T544_A1.5681.00
196_P260_I1.5631.00
427_I431_T1.5591.00
187_T190_F1.5571.00
199_L262_F1.5571.00
48_L52_L1.5441.00
366_G455_A1.5401.00
345_S367_L1.5311.00
390_L415_I1.5241.00
108_E446_I1.5231.00
515_S518_A1.5231.00
448_K452_L1.5221.00
444_S447_K1.5201.00
106_S116_L1.5141.00
500_S504_I1.5031.00
122_L149_P1.4941.00
542_A547_N1.4921.00
550_R554_K1.4881.00
430_I435_I1.4801.00
511_F515_S1.4731.00
45_L49_P1.4671.00
413_A417_M1.4661.00
180_A201_V1.4621.00
213_M276_F1.4601.00
500_S508_L1.4601.00
245_V303_L1.4591.00
502_L505_I1.4551.00
136_Y182_F1.4531.00
543_F546_A1.4491.00
267_M411_T1.4361.00
90_F333_F1.4361.00
53_I56_I1.4291.00
466_P470_Y1.4271.00
56_I60_F1.4251.00
512_S515_S1.4191.00
501_P504_I1.4161.00
96_T128_T1.4161.00
59_I62_K1.4131.00
341_G451_I1.4131.00
298_N422_A1.4061.00
50_P57_F1.4061.00
46_Y52_L1.4021.00
308_L393_L1.3971.00
249_L329_I1.3961.00
505_I515_S1.3931.00
59_I63_K1.3861.00
369_L455_A1.3821.00
503_Y506_L1.3791.00
85_N88_L1.3781.00
81_I134_D1.3761.00
88_L246_Y1.3661.00
126_G145_I1.3591.00
90_F329_I1.3421.00
554_K558_R1.3371.00
467_Y470_Y1.3241.00
165_F169_A1.3221.00
475_S479_L1.3171.00
359_K363_I1.3161.00
507_L511_F1.3031.00
363_I442_Q1.2971.00
509_V516_Y1.2951.00
515_S519_F1.2841.00
200_I265_T1.2751.00
501_P508_L1.2731.00
504_I507_L1.2711.00
60_F63_K1.2681.00
334_A385_A1.2681.00
199_L254_L1.2681.00
502_L506_L1.2671.00
270_G300_G1.2651.00
515_S520_G1.2601.00
510_A517_L1.2581.00
249_L328_V1.2561.00
71_I78_I1.2551.00
541_T547_N1.2541.00
498_G503_Y1.2481.00
456_L460_I1.2451.00
44_L47_T1.2451.00
197_V201_V1.2431.00
498_G502_L1.2411.00
203_T266_I1.2341.00
497_G501_P1.2331.00
540_Y543_F1.2331.00
379_P384_V1.2281.00
50_P54_S1.2251.00
58_S61_N1.2241.00
94_I333_F1.2241.00
50_P59_I1.2151.00
159_K227_T1.2141.00
199_L255_T1.2111.00
331_Y338_A1.2041.00
87_V329_I1.2011.00
366_G451_I1.1971.00
503_Y514_V1.1971.00
57_F60_F1.1961.00
179_L183_I1.1961.00
496_F500_S1.1961.00
497_G500_S1.1961.00
278_A418_G1.1921.00
101_L450_P1.1911.00
107_I446_I1.1911.00
511_F516_Y1.1861.00
127_M240_M1.1841.00
275_F414_I1.1801.00
91_F332_S1.1791.00
542_A546_A1.1781.00
387_W391_E1.1781.00
246_Y250_K1.1771.00
137_L188_T1.1761.00
357_S436_F1.1751.00
123_T150_A1.1751.00
500_S514_V1.1751.00
294_S425_L1.1741.00
47_T53_I1.1741.00
516_Y519_F1.1661.00
452_L456_L1.1601.00
496_F499_I1.1591.00
46_Y49_P1.1541.00
417_M421_L1.1511.00
555_K559_P1.1491.00
44_L104_I1.1441.00
345_S366_G1.1431.00
275_F418_G1.1421.00
53_I57_F1.1411.00
391_E395_M1.1391.00
514_V517_L1.1361.00
267_M307_S1.1321.00
47_T59_I1.1261.00
551_Q555_K1.1211.00
558_R561_E1.1211.00
551_Q554_K1.1201.00
537_K544_A1.1191.00
506_L509_V1.1171.00
538_E541_T1.1151.00
351_K355_T1.1131.00
352_Q441_E1.1121.00
527_A531_N1.1111.00
388_L391_E1.1061.00
500_S507_L1.1031.00
134_D191_N1.0991.00
530_W533_G1.0971.00
104_I449_Y1.0971.00
57_F61_N1.0961.00
557_L560_E1.0931.00
374_M426_L1.0911.00
505_I510_A1.0911.00
44_L100_I1.0891.00
470_Y473_K1.0881.00
285_E294_S1.0801.00
287_T429_Y1.0711.00
272_F410_M1.0701.00
369_L459_L1.0671.00
586_R590_I1.0651.00
357_S439_T1.0621.00
536_E539_E1.0601.00
541_T548_N1.0561.00
450_P453_L1.0551.00
449_Y453_L1.0531.00
548_N552_M1.0521.00
540_Y544_A1.0511.00
544_A547_N1.0501.00
50_P60_F1.0501.00
53_I62_K1.0491.00
44_L48_L1.0491.00
43_T46_Y1.0481.00
268_A272_F1.0451.00
506_L510_A1.0441.00
135_G189_N1.0401.00
47_T54_S1.0381.00
533_G537_K1.0381.00
455_A458_V1.0291.00
545_M550_R1.0281.00
544_A548_N1.0241.00
49_P54_S1.0241.00
371_A375_S1.0241.00
123_T127_M1.0151.00
97_S101_L1.0141.00
126_G149_P1.0141.00
49_P53_I1.0121.00
98_V340_T1.0111.00
508_L514_V1.0091.00
84_Y88_L1.0081.00
81_I189_N1.0081.00
505_I509_V1.0021.00
53_I58_S1.0011.00
182_F188_T1.0011.00
56_I62_K1.0001.00
349_Q433_T1.0001.00
554_K557_L0.9981.00
578_Y581_A0.9981.00
557_L561_E0.9951.00
140_L182_F0.9951.00
518_A522_P0.9921.00
365_I368_T0.9911.00
184_I197_V0.9901.00
142_G145_I0.9871.00
548_N551_Q0.9871.00
78_I137_L0.9861.00
50_P62_K0.9851.00
271_A411_T0.9851.00
174_S208_I0.9841.00
348_L442_Q0.9831.00
524_I529_T0.9831.00
46_Y50_P0.9831.00
52_L55_I0.9831.00
225_H233_S0.9791.00
69_T79_T0.9771.00
351_K447_K0.9761.00
103_S120_Y0.9741.00
358_K436_F0.9711.00
181_G198_P0.9711.00
507_L510_A0.9681.00
511_F514_V0.9671.00
47_T124_I0.9631.00
476_T480_G0.9611.00
502_L516_Y0.9601.00
498_G505_I0.9581.00
500_S512_S0.9571.00
54_S59_I0.9541.00
297_E422_A0.9531.00
298_N331_Y0.9521.00
505_I512_S0.9511.00
390_L508_L0.9501.00
457_I461_L0.9491.00
541_T546_A0.9461.00
69_T72_S0.9461.00
112_Y355_T0.9431.00
587_F591_F0.9431.00
499_I503_Y0.9411.00
445_K452_L0.9381.00
116_L231_N0.9360.99
368_T371_A0.9310.99
590_I593_K0.9300.99
279_L421_L0.9280.99
507_L512_S0.9270.99
101_L340_T0.9270.99
248_I306_L0.9230.99
477_T480_G0.9230.99
367_L371_A0.9210.99
512_S518_A0.9180.99
529_T533_G0.9180.99
195_S258_I0.9150.99
469_I473_K0.9120.99
264_L268_A0.9120.99
225_H241_T0.9110.99
45_L52_L0.9110.99
541_T545_M0.9100.99
278_A297_E0.9060.99
442_Q448_K0.9050.99
278_A294_S0.9050.99
196_P200_I0.9040.99
426_L429_Y0.9040.99
529_T532_N0.9030.99
503_Y515_S0.9020.99
470_Y474_N0.9020.99
41_M44_L0.9010.99
559_P562_E0.9000.99
517_L520_G0.8970.99
379_P463_F0.8960.99
509_V512_S0.8950.99
537_K548_N0.8940.99
83_E134_D0.8920.99
276_F280_Y0.8920.99
177_L201_V0.8860.99
504_I510_A0.8860.99
47_T58_S0.8820.99
83_E191_N0.8770.99
472_Y475_S0.8760.99
272_F276_F0.8760.99
582_N586_R0.8750.99
591_F594_T0.8750.99
84_Y132_N0.8730.99
88_L250_K0.8730.99
103_S121_I0.8710.99
101_L453_L0.8710.99
267_M304_V0.8700.99
174_S215_F0.8690.99
579_K582_N0.8690.99
597_N602_W0.8660.99
123_T240_M0.8650.99
520_G523_K0.8640.99
536_E542_A0.8640.99
134_D189_N0.8630.99
526_K530_W0.8630.99
535_N539_E0.8620.99
508_L516_Y0.8620.99
422_A425_L0.8600.99
472_Y476_T0.8590.99
260_I264_L0.8590.99
58_S63_K0.8590.99
593_K598_S0.8580.99
545_M548_N0.8560.99
40_K44_L0.8560.99
196_P262_F0.8540.99
552_M556_I0.8540.99
44_L107_I0.8540.99
500_S505_I0.8530.99
502_L512_S0.8530.99
140_L179_L0.8530.99
539_E543_F0.8520.99
51_F57_F0.8510.99
469_I472_Y0.8500.99
43_T50_P0.8490.99
263_S267_M0.8470.99
524_I527_A0.8440.99
443_L447_K0.8440.99
52_L60_F0.8430.99
546_A550_R0.8410.99
536_E543_F0.8410.99
505_I516_Y0.8370.99
381_I461_L0.8370.99
592_A596_I0.8320.99
504_I516_Y0.8290.99
542_A549_I0.8270.99
550_R557_L0.8260.99
566_P570_L0.8260.99
55_I97_S0.8240.99
258_I262_F0.8230.99
200_I262_F0.8210.99
498_G512_S0.8190.99
538_E542_A0.8180.99
42_N46_Y0.8180.99
290_I432_Y0.8170.99
298_N425_L0.8160.99
290_I428_R0.8150.99
178_I247_G0.8130.99
287_T356_Y0.8110.99
48_L53_I0.8110.99
588_G592_A0.8110.99
418_G421_L0.8100.99
528_E531_N0.8090.99
360_I364_E0.8070.98
540_Y546_A0.8050.98
475_S480_G0.8040.98
410_M413_A0.8030.98
511_F518_A0.8020.98
454_S462_G0.7950.98
507_L516_Y0.7930.98
52_L59_I0.7920.98
135_G138_L0.7890.98
504_I512_S0.7880.98
449_Y452_L0.7880.98
256_Q325_L0.7870.98
46_Y56_I0.7850.98
57_F62_K0.7850.98
120_Y232_F0.7850.98
72_S77_L0.7840.98
197_V200_I0.7830.98
589_K593_K0.7820.98
537_K540_Y0.7790.98
468_L471_P0.7770.98
139_F247_G0.7760.98
46_Y51_F0.7740.98
471_P474_N0.7710.98
453_L457_I0.7700.98
443_L448_K0.7690.98
212_M303_L0.7690.98
44_L50_P0.7680.98
508_L512_S0.7680.98
150_A240_M0.7650.98
358_K438_N0.7650.98
290_I433_T0.7600.98
553_L556_I0.7590.98
102_A120_Y0.7590.98
108_E447_K0.7580.98
222_P293_F0.7560.98
54_S57_F0.7560.98
297_E425_L0.7540.98
338_A382_G0.7530.98
81_I135_G0.7530.98
545_M549_I0.7510.98
502_L514_V0.7510.98
202_A251_I0.7480.98
335_H339_K0.7480.98
266_I306_L0.7450.97
51_F96_T0.7440.97
381_I458_V0.7420.97
119_L149_P0.7420.97
45_L50_P0.7400.97
330_L334_A0.7400.97
609_L613_V0.7390.97
301_A419_E0.7390.97
54_S58_S0.7380.97
501_P515_S0.7380.97
207_I307_S0.7360.97
361_R438_N0.7360.97
522_P525_R0.7320.97
245_V306_L0.7320.97
55_I59_I0.7300.97
525_R530_W0.7290.97
265_T269_I0.7280.97
84_Y89_S0.7280.97
52_L58_S0.7270.97
301_A415_I0.7260.97
467_Y471_P0.7260.97
99_W102_A0.7250.97
118_P152_V0.7240.97
503_Y512_S0.7220.97
565_L568_Y0.7210.97
96_T100_I0.7200.97
105_F344_L0.7190.97
514_V520_G0.7190.97
221_L233_S0.7190.97
376_G386_S0.7180.97
42_N53_I0.7170.97
123_T241_T0.7160.97
105_F447_K0.7160.97
196_P258_I0.7150.97
55_I58_S0.7130.97
580_L584_I0.7130.97
368_T435_I0.7120.97
538_E548_N0.7100.97
517_L521_K0.7080.97
50_P96_T0.7080.97
542_A545_M0.7070.97
539_E544_A0.7070.97
372_S427_I0.7060.97
527_A530_W0.7050.96
518_A521_K0.7050.96
304_V411_T0.7050.96
330_L384_V0.7050.96
45_L53_I0.7020.96
577_L581_A0.7020.96
396_F408_F0.7010.96
47_T62_K0.7010.96
172_E175_T0.7010.96
498_G510_A0.7000.96
505_I514_V0.6990.96
592_A595_L0.6980.96
501_P507_L0.6960.96
531_N534_V0.6950.96
508_L515_S0.6950.96
360_I368_T0.6930.96
109_Y230_S0.6930.96
524_I528_E0.6920.96
501_P505_I0.6890.96
507_L514_V0.6880.96
268_A271_A0.6870.96
504_I508_L0.6860.96
267_M308_L0.6860.96
474_N477_T0.6850.96
519_F522_P0.6850.96
94_I332_S0.6850.96
360_I435_I0.6850.96
56_I63_K0.6830.96
426_L430_I0.6820.96
436_F439_T0.6820.96
72_S75_I0.6820.96
210_M239_T0.6800.96
594_T597_N0.6790.96
473_K477_T0.6770.96
578_Y582_N0.6760.96
564_F567_T0.6760.96
420_G424_A0.6750.96
464_T467_Y0.6740.95
333_F465_L0.6730.95
40_K107_I0.6700.95
274_I304_V0.6700.95
414_I418_G0.6680.95
48_L56_I0.6680.95
466_P471_P0.6670.95
298_N301_A0.6660.95
350_E356_Y0.6650.95
225_H295_T0.6640.95
583_S586_R0.6630.95
102_A344_L0.6610.95
47_T57_F0.6600.95
447_K451_I0.6590.95
287_T349_Q0.6580.95
497_G504_I0.6580.95
50_P61_N0.6580.95
468_L472_Y0.6570.95
349_Q359_K0.6570.95
40_K47_T0.6550.95
503_Y508_L0.6510.95
49_P60_F0.6510.95
275_F279_L0.6490.94
583_S587_F0.6480.94
599_S602_W0.6470.94
213_M277_G0.6470.94
161_N164_P0.6470.94
209_K288_K0.6460.94
51_F62_K0.6440.94
284_N289_G0.6440.94
51_F56_I0.6430.94
466_P473_K0.6420.94
362_N440_R0.6410.94
362_N438_N0.6410.94
344_L451_I0.6410.94
390_L504_I0.6410.94
500_S513_I0.6410.94
512_S520_G0.6390.94
501_P516_Y0.6390.94
501_P514_V0.6390.94
47_T56_I0.6390.94
51_F58_S0.6380.94
538_E544_A0.6380.94
565_L570_L0.6380.94
146_M228_A0.6370.94
548_N553_L0.6370.94
170_F211_G0.6370.94
519_F523_K0.6360.94
510_A520_G0.6350.94
227_T289_G0.6320.94
51_F59_I0.6280.93
577_L580_L0.6280.93
452_L455_A0.6280.93
95_S127_M0.6250.93
547_N550_R0.6250.93
46_Y60_F0.6240.93
550_R558_R0.6240.93
512_S517_L0.6240.93
196_P265_T0.6240.93
207_I265_T0.6200.93
55_I62_K0.6190.93
571_D575_E0.6180.93
367_L430_I0.6180.93
543_F549_I0.6170.93
325_L329_I0.6160.93
525_R528_E0.6150.93
271_A304_V0.6150.93
127_M239_T0.6150.93
366_G448_K0.6130.93
121_I125_L0.6120.93
54_S61_N0.6110.93
586_R612_I0.6100.92
178_I202_A0.6100.92
537_K543_F0.6100.92
535_N538_E0.6080.92
136_Y190_F0.6080.92
56_I61_N0.6080.92
547_N551_Q0.6070.92
69_T77_L0.6070.92
575_E579_K0.6070.92
280_Y293_F0.6060.92
103_S124_I0.6020.92
525_R529_T0.6010.92
290_I429_Y0.6000.92
289_G341_G0.5990.92
287_T350_E0.5990.92
337_V461_L0.5990.92
206_F247_G0.5990.92
352_Q443_L0.5990.92
338_A425_L0.5990.92
102_A124_I0.5980.92
127_M225_H0.5970.92
252_T256_Q0.5960.92
421_L424_A0.5950.92
269_I272_F0.5930.91
337_V381_I0.5920.91
554_K561_E0.5920.91
536_E541_T0.5910.91
534_V537_K0.5910.91
294_S335_H0.5900.91
466_P469_I0.5900.91
52_L62_K0.5900.91
454_S458_V0.5900.91
281_G290_I0.5900.91
328_V334_A0.5890.91
549_I557_L0.5870.91
467_Y476_T0.5870.91
351_K443_L0.5860.91
109_Y127_M0.5850.91
550_R556_I0.5840.91
505_I518_A0.5830.91
591_F595_L0.5820.91
382_G385_A0.5820.91
280_Y542_A0.5810.91
91_F237_S0.5810.91
135_G188_T0.5800.90
476_T479_L0.5770.90
87_V249_L0.5740.90
526_K529_T0.5740.90
126_G129_I0.5740.90
469_I474_N0.5730.90
496_F503_Y0.5720.90
93_I97_S0.5720.90
602_W605_I0.5720.90
151_Y164_P0.5700.90
71_I79_T0.5700.90
365_I369_L0.5690.90
473_K478_I0.5680.90
535_N541_T0.5680.90
525_R531_N0.5680.90
45_L48_L0.5680.90
556_I560_E0.5680.90
502_L508_L0.5660.89
127_M150_A0.5660.89
106_S344_L0.5660.89
593_K596_I0.5660.89
119_L380_N0.5650.89
208_I228_A0.5650.89
536_E544_A0.5630.89
133_S139_F0.5630.89
203_T265_T0.5610.89
581_A584_I0.5590.89
40_K50_P0.5590.89
590_I594_T0.5580.89
284_N293_F0.5570.89
539_E542_A0.5560.89
502_L520_G0.5530.88
41_M48_L0.5520.88
233_S295_T0.5520.88
431_T435_I0.5520.88
587_F590_I0.5510.88
500_S506_L0.5510.88
445_K448_K0.5510.88
515_S522_P0.5500.88
54_S92_S0.5500.88
541_T551_Q0.5500.88
359_K434_S0.5500.88
98_V102_A0.5490.88
297_E386_S0.5480.88
496_F501_P0.5470.88
380_N459_L0.5460.88
523_K526_K0.5450.88
381_I385_A0.5450.88
509_V518_A0.5450.88
502_L509_V0.5440.87
127_M210_M0.5430.87
89_S93_I0.5430.87
195_S199_L0.5430.87
349_Q363_I0.5420.87
123_T171_G0.5420.87
88_L132_N0.5400.87
294_S339_K0.5400.87
341_G458_V0.5390.87
584_I587_F0.5390.87
295_T335_H0.5380.87
274_I301_A0.5370.87
82_Y132_N0.5360.87
425_L428_R0.5360.87
463_F467_Y0.5360.87
167_F228_A0.5350.87
210_M225_H0.5340.86
260_I265_T0.5340.86
501_P511_F0.5330.86
559_P564_F0.5330.86
49_P56_I0.5320.86
40_K51_F0.5320.86
61_N89_S0.5310.86
394_F397_S0.5310.86
47_T55_I0.5300.86
51_F54_S0.5290.86
213_M545_M0.5280.86
327_T392_N0.5280.86
55_I93_I0.5270.86
105_F355_T0.5270.86
120_Y149_P0.5260.86
499_I502_L0.5260.86
222_P296_I0.5240.85
161_N165_F0.5240.85
356_Y433_T0.5240.85
301_A418_G0.5240.85
576_Y579_K0.5230.85
109_Y233_S0.5230.85
277_G300_G0.5220.85
302_I332_S0.5220.85
127_M233_S0.5220.85
234_A344_L0.5220.85
388_L392_N0.5210.85
48_L51_F0.5210.85
233_S288_K0.5210.85
71_I77_L0.5200.85
580_L585_R0.5200.85
386_S425_L0.5200.85
277_G296_I0.5190.85
446_I450_P0.5190.85
40_K43_T0.5180.85
298_N338_A0.5170.85
542_A550_R0.5160.85
198_P202_A0.5160.85
177_L205_G0.5160.85
43_T121_I0.5150.84
556_I559_P0.5150.84
98_V336_S0.5150.84
230_S295_T0.5140.84
134_D138_L0.5130.84
305_A310_M0.5110.84
562_E567_T0.5110.84
41_M47_T0.5110.84
104_I450_P0.5100.84
155_G167_F0.5100.84
553_L557_L0.5090.84
587_F594_T0.5080.84
93_I102_A0.5070.84
214_P296_I0.5070.84
109_Y123_T0.5070.84
163_P227_T0.5070.84
501_P510_A0.5070.84
54_S96_T0.5070.84
49_P57_F0.5060.83
207_I212_M0.5060.83
109_Y288_K0.5060.83
287_T433_T0.5050.83
42_N49_P0.5040.83
584_I588_G0.5040.83
460_I464_T0.5040.83
43_T61_N0.5030.83
371_A374_M0.5020.83
104_I446_I0.5020.83
147_T171_G0.5010.83
509_V514_V0.5010.83
268_A410_M0.5010.83
123_T225_H0.5010.83
593_K597_N0.5000.83
526_K531_N0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3rkoL 1 0.913 100 0.382 Contact Map
4he8L 1 0.905 100 0.394 Contact Map
3rkoM 1 0.7279 100 0.483 Contact Map
4he8M 1 0.7021 100 0.508 Contact Map
3rkoN 1 0.6973 100 0.526 Contact Map
4he8N 1 0.6522 100 0.545 Contact Map
1tvsA 1 0.0403 38.1 0.977 Contact Map
3mi9C 1 0.0081 32.7 0.978 Contact Map
1tacA 1 0.0644 29 0.978 Contact Map
2kluA 1 0.0676 21.7 0.979 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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