GREMLIN Database
Q97ZA6 - NADH-Ubiquinone/plastoquinone related
UniProt: Q97ZA6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 440 (424)
Sequences: 20465 (12469)
Seq/√Len: 605.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_T239_M4.7201.00
311_G348_S4.7101.00
106_F119_G4.4951.00
172_T175_E3.8071.00
64_L109_I3.6781.00
132_I143_T3.4991.00
145_R212_D3.2491.00
71_Y101_A3.2401.00
270_H326_K3.2191.00
304_A359_A3.1621.00
301_L363_G2.9871.00
258_I385_I2.8541.00
254_T291_T2.7161.00
170_T175_E2.7041.00
275_F316_S2.6811.00
269_W329_E2.6631.00
103_S122_L2.6091.00
64_L105_L2.5671.00
67_I108_V2.5371.00
325_E330_N2.5301.00
327_R330_N2.4991.00
160_S192_L2.4701.00
15_S32_S2.3841.00
203_V287_L2.3791.00
346_L398_V2.3731.00
55_F111_N2.3111.00
349_S393_S2.2621.00
78_S93_Y2.2441.00
13_I102_S2.2221.00
68_A105_L2.1981.00
230_L279_T2.1331.00
288_L382_L2.0571.00
274_M328_I2.0561.00
266_T391_F2.0421.00
289_G367_I2.0121.00
198_G203_V1.9821.00
175_E178_T1.8961.00
57_T60_T1.8811.00
415_K419_F1.8411.00
248_N252_I1.8291.00
259_I385_I1.8101.00
278_S392_I1.8031.00
338_L341_T1.8021.00
116_M236_V1.7921.00
269_W327_R1.7781.00
202_G210_L1.7771.00
34_V72_L1.7681.00
142_A216_E1.7651.00
262_S281_E1.7471.00
300_I363_G1.7291.00
251_V291_T1.7191.00
268_Q273_R1.7081.00
113_Y176_I1.6991.00
307_F427_I1.6931.00
38_I42_F1.6761.00
163_F189_A1.6691.00
426_I430_V1.6611.00
111_N174_T1.6421.00
368_L382_L1.6381.00
204_F256_L1.6371.00
66_V306_A1.6351.00
24_L27_T1.6341.00
194_L198_G1.6261.00
12_P15_S1.6241.00
113_Y240_V1.6241.00
271_I397_N1.6081.00
395_N400_K1.6081.00
22_L26_K1.6071.00
175_E179_K1.5891.00
9_L12_P1.5871.00
110_M115_L1.5681.00
34_V38_I1.5641.00
37_S69_S1.5441.00
60_T235_Y1.5441.00
255_T381_I1.5321.00
96_L129_L1.5151.00
335_H342_S1.5141.00
238_Y290_L1.5101.00
341_T412_E1.5061.00
165_Y171_L1.4961.00
167_N189_A1.4931.00
130_L221_I1.4901.00
55_F58_K1.4841.00
369_Q373_Q1.4681.00
37_S41_I1.4671.00
286_A298_A1.4631.00
62_F303_L1.4501.00
197_F236_V1.4491.00
75_T97_L1.4441.00
112_N171_L1.4371.00
36_T40_S1.4351.00
107_T232_A1.4321.00
39_I43_L1.4271.00
203_V253_F1.4241.00
32_S36_T1.4231.00
184_I188_L1.4181.00
250_F291_T1.4101.00
247_T251_V1.3901.00
112_N172_T1.3891.00
29_S33_A1.3891.00
160_S196_G1.3881.00
162_I166_Y1.3801.00
262_S385_I1.3731.00
414_P417_I1.3601.00
116_M173_V1.3591.00
288_L371_L1.3571.00
345_L349_S1.3491.00
347_L425_S1.3491.00
290_L298_A1.3461.00
33_A36_T1.3371.00
70_I310_A1.3281.00
75_T94_Y1.3261.00
312_A348_S1.3191.00
33_A40_S1.3151.00
9_L102_S1.3121.00
53_F111_N1.3091.00
56_I109_I1.3071.00
28_L32_S1.3051.00
23_K26_K1.3021.00
160_S193_A1.2871.00
31_L35_L1.2841.00
422_L426_I1.2831.00
237_V287_L1.2821.00
238_Y298_A1.2721.00
33_A37_S1.2681.00
194_L250_F1.2661.00
212_D273_R1.2641.00
308_G351_A1.2631.00
423_V427_I1.2571.00
17_V20_F1.2511.00
198_G253_F1.2441.00
149_I208_T1.2431.00
16_N20_F1.2371.00
160_S189_A1.2221.00
342_S403_F1.2221.00
292_I297_G1.2211.00
137_E216_E1.2161.00
40_S68_A1.2141.00
420_I423_V1.2131.00
70_I306_A1.2111.00
260_T264_I1.2091.00
254_T284_N1.1911.00
80_N83_K1.1881.00
77_Y314_Y1.1851.00
342_S398_V1.1841.00
292_I371_L1.1821.00
415_K418_T1.1771.00
138_T216_E1.1751.00
23_K27_T1.1671.00
63_F302_L1.1661.00
117_W158_L1.1611.00
21_K24_L1.1611.00
62_F299_I1.1591.00
304_A363_G1.1541.00
315_S345_L1.1531.00
178_T181_E1.1501.00
345_L397_N1.1501.00
344_S425_S1.1461.00
153_G199_T1.1451.00
341_T413_E1.1451.00
320_L326_K1.1401.00
111_N172_T1.1381.00
161_I193_A1.1371.00
289_G298_A1.1371.00
157_A196_G1.1341.00
141_E145_R1.1321.00
157_A161_I1.1301.00
136_S139_S1.1251.00
22_L25_I1.1221.00
389_T392_I1.1071.00
73_L423_V1.1051.00
59_F238_Y1.1041.00
315_S421_S1.1021.00
348_S425_S1.0981.00
252_I256_L1.0961.00
163_F185_I1.0911.00
99_S126_T1.0881.00
416_L420_I1.0841.00
366_F369_Q1.0761.00
68_A72_L1.0731.00
9_L16_N1.0711.00
271_I316_S1.0661.00
174_T178_T1.0661.00
328_I401_M1.0631.00
103_S126_T1.0591.00
25_I28_L1.0571.00
346_L402_I1.0571.00
281_E389_T1.0551.00
114_G171_L1.0531.00
15_S19_F1.0521.00
199_T206_M1.0511.00
430_V434_L1.0511.00
70_I227_G1.0501.00
349_S398_V1.0491.00
322_V338_L1.0361.00
56_I61_T1.0331.00
167_N185_I1.0311.00
352_V393_S1.0301.00
165_Y168_Y1.0271.00
21_K25_I1.0251.00
254_T288_L1.0221.00
26_K29_S1.0201.00
377_I380_F1.0191.00
204_F260_T1.0171.00
340_L343_V1.0151.00
29_S32_S1.0151.00
261_A284_N1.0141.00
29_S75_T1.0041.00
80_N416_L1.0041.00
113_Y161_I1.0031.00
289_G297_G1.0011.00
72_L76_L1.0011.00
103_S119_G1.0011.00
211_P277_Y0.9911.00
168_Y176_I0.9891.00
344_S421_S0.9881.00
305_H309_K0.9881.00
25_I29_S0.9871.00
350_L355_T0.9861.00
201_A234_T0.9851.00
427_I431_L0.9841.00
60_T239_M0.9841.00
398_V403_F0.9761.00
219_S272_K0.9711.00
80_N414_P0.9701.00
98_N102_S0.9661.00
10_L14_I0.9661.00
323_L331_I0.9641.00
59_F299_I0.9631.00
262_S392_I0.9601.00
189_A193_A0.9591.00
187_K191_A0.9531.00
187_K246_L0.9491.00
248_N251_V0.9491.00
97_L224_L0.9481.00
15_S20_F0.9471.00
234_T302_L0.9471.00
13_I17_V0.9471.00
163_F167_N0.9421.00
258_I288_L0.9421.00
182_N186_T0.9411.00
63_F235_Y0.9391.00
12_P16_N0.9371.00
69_S73_L0.9371.00
282_N389_T0.9351.00
12_P20_F0.9351.00
156_L195_I0.9341.00
344_S422_L0.9291.00
380_F384_V0.9281.00
270_H327_R0.9271.00
184_I187_K0.9271.00
340_L344_S0.9261.00
340_L422_L0.9261.00
262_S388_A0.9231.00
332_G407_E0.9231.00
223_A314_Y0.9181.00
222_S230_L0.9171.00
27_T31_L0.9161.00
77_Y317_G0.9151.00
26_K30_V0.9141.00
156_L192_L0.9131.00
345_L402_I0.9131.00
100_F104_M0.9121.00
40_S43_L0.9111.00
282_N301_L0.9111.00
318_I341_T0.9101.00
342_S402_I0.9091.00
127_S229_L0.9071.00
425_S428_P0.9061.00
117_W121_E0.9061.00
286_A302_L0.9051.00
300_I304_A0.9041.00
365_F369_Q0.9041.00
13_I16_N0.9031.00
128_A143_T0.9011.00
139_S216_E0.9001.00
117_W161_I0.9001.00
60_T64_L0.8991.00
46_L49_I0.8991.00
332_G400_K0.8971.00
105_L109_I0.8971.00
36_T68_A0.8951.00
188_L192_L0.8941.00
425_S429_L0.8931.00
29_S94_Y0.8911.00
35_L39_I0.8881.00
311_G424_S0.8871.00
67_I101_A0.8861.00
71_Y97_L0.8851.00
418_T422_L0.8841.00
215_S226_S0.8831.00
234_T286_A0.8831.00
322_V417_I0.8821.00
321_K411_S0.8821.00
194_L237_V0.8791.00
319_V334_L0.8791.00
385_I388_A0.8781.00
235_Y239_M0.8771.00
131_I213_A0.8761.00
183_N187_K0.8741.00
37_S68_A0.8731.00
164_I189_A0.8701.00
359_A431_L0.8701.00
282_N392_I0.8681.00
93_Y220_P0.8681.00
258_I284_N0.8681.00
271_I331_I0.8671.00
226_S279_T0.8671.00
256_L260_T0.8631.00
26_K79_M0.8581.00
140_L143_T0.8581.00
11_I15_S0.8571.00
26_K33_A0.8551.00
251_V254_T0.8531.00
294_Q297_G0.8511.00
251_V255_T0.8491.00
104_M229_L0.8451.00
26_K32_S0.8441.00
285_L367_I0.8431.00
359_A428_P0.8431.00
27_T30_V0.8421.00
30_V33_A0.8411.00
261_A264_I0.8411.00
390_A394_I0.8361.00
338_L412_E0.8281.00
263_I388_A0.8271.00
176_I179_K0.8261.00
318_I413_E0.8241.00
343_V402_I0.8231.00
104_M123_T0.8201.00
226_S309_K0.8191.00
74_S314_Y0.8191.00
170_T176_I0.8191.00
274_M397_N0.8181.00
279_T305_H0.8171.00
53_F172_T0.8151.00
234_T287_L0.8131.00
54_F109_I0.8111.00
164_I176_I0.8111.00
297_G370_T0.8101.00
100_F127_S0.8081.00
170_T173_V0.8051.00
254_T287_L0.8041.00
351_A358_F0.8011.00
183_N186_T0.7991.00
419_F422_L0.7991.00
120_V157_A0.7961.00
151_S154_V0.7961.00
26_K37_S0.7941.00
66_V303_L0.7901.00
275_F312_A0.7891.00
234_T283_M0.7861.00
261_A281_E0.7851.00
123_T229_L0.7851.00
108_V235_Y0.7831.00
308_G360_T0.7811.00
131_I217_A0.7811.00
173_V177_L0.7801.00
32_S35_L0.7801.00
25_I33_A0.7791.00
259_I263_I0.7781.00
36_T39_I0.7781.00
177_L181_E0.7751.00
9_L15_S0.7751.00
138_T215_S0.7741.00
318_I421_S0.7741.00
413_E418_T0.7741.00
53_F112_N0.7731.00
138_T141_E0.7681.00
393_S397_N0.7671.00
237_V290_L0.7671.00
12_P19_F0.7661.00
104_M228_V0.7661.00
219_S317_G0.7651.00
73_L420_I0.7651.00
87_I92_L0.7651.00
79_M416_L0.7641.00
123_T232_A0.7641.00
376_Y379_E0.7631.00
268_Q274_M0.7631.00
358_F362_I0.7611.00
15_S18_G0.7571.00
265_L392_I0.7551.00
191_A195_I0.7551.00
131_I225_F0.7551.00
190_V246_L0.7551.00
33_A75_T0.7541.00
65_L69_S0.7541.00
342_S346_L0.7521.00
67_I104_M0.7491.00
10_L13_I0.7471.00
9_L18_G0.7461.00
39_I42_F0.7461.00
328_I400_K0.7441.00
128_A150_V0.7421.00
12_P17_V0.7411.00
180_P186_T0.7361.00
413_E417_I0.7331.00
14_I18_G0.7321.00
153_G196_G0.7321.00
251_V288_L0.7301.00
262_S278_S0.7301.00
177_L242_Q0.7301.00
25_I43_L0.7251.00
343_V346_L0.7251.00
16_N99_S0.7221.00
254_T258_I0.7201.00
419_F423_V0.7191.00
29_S98_N0.7171.00
357_P433_I0.7171.00
424_S428_P0.7171.00
354_G364_E0.7121.00
112_N115_L0.7111.00
21_K26_K0.7101.00
353_T390_A0.7061.00
29_S35_L0.7041.00
20_F95_I0.7031.00
285_L385_I0.7001.00
343_V347_L0.7001.00
59_F235_Y0.6991.00
91_R95_I0.6991.00
294_Q370_T0.6981.00
255_T288_L0.6951.00
410_V413_E0.6931.00
28_L31_L0.6931.00
336_T339_K0.6921.00
121_E200_K0.6921.00
388_A392_I0.6891.00
292_I374_K0.6891.00
255_T259_I0.6861.00
100_F229_L0.6861.00
215_S270_H0.6841.00
9_L13_I0.6831.00
344_S348_S0.6801.00
182_N185_I0.6791.00
188_L191_A0.6781.00
349_S397_N0.6771.00
26_K36_T0.6731.00
50_K114_G0.6711.00
81_Y220_P0.6671.00
32_S38_I0.6661.00
315_S348_S0.6661.00
375_G378_I0.6641.00
9_L20_F0.6611.00
59_F63_F0.6601.00
222_S272_K0.6581.00
61_T65_L0.6581.00
14_I17_V0.6571.00
9_L54_F0.6571.00
111_N115_L0.6571.00
211_P280_I0.6551.00
25_I36_T0.6551.00
332_G404_T0.6541.00
351_A360_T0.6541.00
226_S230_L0.6531.00
120_V232_A0.6531.00
100_F224_L0.6531.00
249_I252_I0.6511.00
25_I32_S0.6511.00
217_A222_S0.6511.00
27_T36_T0.6511.00
227_G310_A0.6511.00
387_L391_F0.6481.00
301_L308_G0.6481.00
208_T211_P0.6471.00
394_I399_T0.6461.00
74_S223_A0.6461.00
328_I397_N0.6461.00
337_K406_R0.6461.00
242_Q245_P0.6451.00
144_W148_I0.6441.00
282_N309_K0.6441.00
68_A101_A0.6441.00
217_A226_S0.6431.00
278_S309_K0.6411.00
56_I60_T0.6401.00
262_S389_T0.6391.00
268_Q277_Y0.6371.00
429_L433_I0.6351.00
30_V34_V0.6321.00
340_L418_T0.6311.00
278_S305_H0.6301.00
93_Y133_A0.6301.00
308_G428_P0.6271.00
31_L34_V0.6271.00
55_F174_T0.6271.00
134_E137_E0.6271.00
325_E331_I0.6261.00
308_G352_V0.6261.00
381_I385_I0.6251.00
264_I277_Y0.6241.00
33_A72_L0.6211.00
158_L162_I0.6201.00
429_L432_G0.6191.00
370_T374_K0.6171.00
346_L403_F0.6171.00
356_P361_F0.6171.00
28_L43_L0.6161.00
33_A39_I0.6151.00
71_Y224_L0.6151.00
21_K27_T0.6151.00
171_L175_E0.6141.00
110_M119_G0.6141.00
185_I189_A0.6141.00
210_L230_L0.6131.00
65_L68_A0.6121.00
13_I18_G0.6091.00
263_I267_Y0.6081.00
226_S305_H0.6081.00
36_T43_L0.6071.00
335_H402_I0.6071.00
222_S225_F0.6061.00
315_S344_S0.6041.00
252_I255_T0.6011.00
231_P283_M0.6001.00
24_L28_L0.6001.00
73_L310_A0.5991.00
368_L383_I0.5981.00
318_I417_I0.5961.00
307_F359_A0.5951.00
164_I193_A0.5951.00
35_L38_I0.5941.00
227_G231_P0.5941.00
73_L424_S0.5931.00
74_S97_L0.5921.00
163_F188_L0.5921.00
185_I188_L0.5911.00
113_Y173_V0.5901.00
271_I401_M0.5891.00
192_L196_G0.5881.00
334_L338_L0.5861.00
382_L386_S0.5851.00
67_I105_L0.5841.00
264_I268_Q0.5831.00
78_S220_P0.5831.00
16_N102_S0.5831.00
116_M157_A0.5831.00
63_F67_I0.5811.00
93_Y221_I0.5811.00
337_K410_V0.5801.00
194_L246_L0.5771.00
11_I35_L0.5761.00
259_I381_I0.5761.00
177_L180_P0.5761.00
29_S38_I0.5761.00
380_F383_I0.5741.00
258_I285_L0.5741.00
391_F395_N0.5731.00
264_I267_Y0.5731.00
368_L386_S0.5731.00
278_S282_N0.5721.00
113_Y164_I0.5721.00
417_I420_I0.5711.00
241_Y290_L0.5691.00
38_I41_I0.5691.00
416_L419_F0.5681.00
374_K378_I0.5661.00
190_V244_N0.5661.00
168_Y172_T0.5661.00
117_W154_V0.5661.00
78_S81_Y0.5641.00
344_S418_T0.5631.00
22_L28_L0.5631.00
354_G358_F0.5611.00
9_L19_F0.5591.00
314_Y420_I0.5581.00
127_S130_L0.5561.00
339_K342_S0.5541.00
21_K36_T0.5541.00
13_I20_F0.5541.00
347_L429_L0.5530.99
40_S44_Y0.5520.99
117_W128_A0.5500.99
204_F261_A0.5500.99
318_I322_V0.5490.99
424_S427_I0.5480.99
43_L61_T0.5470.99
346_L350_L0.5460.99
159_F163_F0.5460.99
364_E386_S0.5450.99
215_S273_R0.5440.99
37_S72_L0.5440.99
388_A391_F0.5430.99
413_E416_L0.5420.99
15_S98_N0.5410.99
201_A233_A0.5400.99
24_L32_S0.5390.99
40_S65_L0.5380.99
74_S220_P0.5370.99
383_I386_S0.5360.99
101_A105_L0.5350.99
255_T378_I0.5340.99
269_W278_S0.5330.99
186_T189_A0.5320.99
321_K417_I0.5310.99
96_L126_T0.5290.99
336_T406_R0.5290.99
339_K343_V0.5280.99
328_I331_I0.5280.99
347_L351_A0.5280.99
27_T32_S0.5250.99
289_G370_T0.5240.99
30_V72_L0.5230.99
111_N239_M0.5230.99
319_V331_I0.5230.99
307_F424_S0.5220.99
69_S427_I0.5200.99
9_L17_V0.5190.99
174_T177_L0.5190.99
399_T404_T0.5180.99
124_T150_V0.5170.99
334_L339_K0.5170.99
342_S401_M0.5160.99
22_L27_T0.5160.99
279_T283_M0.5150.99
203_V283_M0.5150.99
29_S36_T0.5140.99
67_I71_Y0.5120.99
415_K420_I0.5110.99
127_S131_I0.5110.99
225_F229_L0.5110.99
354_G360_T0.5110.99
16_N19_F0.5100.99
411_S414_P0.5100.99
370_T373_Q0.5080.99
25_I40_S0.5070.99
210_L213_A0.5070.99
399_T403_F0.5060.99
119_G122_L0.5060.99
222_S305_H0.5050.99
149_I199_T0.5040.99
362_I433_I0.5040.99
276_A279_T0.5030.99
37_S40_S0.5030.99
66_V302_L0.5020.99
282_N285_L0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3rkoM 1 0.9841 100 0.136 Contact Map
3rkoL 1 0.9886 100 0.146 Contact Map
4he8L 1 0.9864 100 0.149 Contact Map
4he8M 1 0.9614 100 0.15 Contact Map
3rkoN 1 0.975 100 0.158 Contact Map
4he8N 1 0.9409 100 0.183 Contact Map
4he8K 1 0.2091 36.5 0.959 Contact Map
3rkoK 1 0.2182 30.1 0.96 Contact Map
4he8J 1 0.3455 11.7 0.967 Contact Map
2gfpA 2 0.7614 3 0.975 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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