GREMLIN Database
Q97Z98 - Sulfate ABC transporter, permease protein
UniProt: Q97Z98 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 265 (233)
Sequences: 71051 (45079)
Seq/√Len: 2953.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
172_K176_S3.8431.00
53_G57_F3.1391.00
164_M173_V2.8801.00
149_Q153_E2.8601.00
151_F185_G2.5171.00
33_G39_V2.5061.00
79_R160_E2.4951.00
50_S53_G2.4901.00
160_E178_V2.4701.00
163_A173_V2.4671.00
61_L133_L2.4441.00
169_S172_K2.4271.00
51_S225_Y2.3851.00
37_F40_K2.3571.00
65_I137_I2.3531.00
40_K44_F2.2931.00
220_Y228_N2.2931.00
37_F41_S2.2731.00
63_I190_G2.2691.00
49_L53_G2.2281.00
170_E173_V2.2261.00
171_F175_T2.1521.00
148_M186_I2.1271.00
168_A172_K2.0341.00
172_K175_T1.9561.00
71_T174_F1.9131.00
125_F128_T1.8721.00
78_S153_E1.8711.00
144_Y189_A1.8671.00
152_F182_S1.8271.00
27_L31_F1.8191.00
159_Y181_L1.8051.00
163_A168_A1.7781.00
253_V257_I1.7661.00
86_E149_Q1.7521.00
71_T182_S1.7291.00
67_V190_G1.7251.00
164_M170_E1.7171.00
160_E173_V1.6881.00
59_S194_I1.6711.00
50_S54_L1.6381.00
217_N220_Y1.6101.00
160_E164_M1.5881.00
62_S197_A1.5791.00
70_F144_Y1.5701.00
57_F129_Y1.5671.00
57_F61_L1.5601.00
225_Y229_E1.5491.00
77_L145_I1.5481.00
41_S236_A1.5361.00
71_T148_M1.5271.00
73_L145_I1.5141.00
144_Y193_S1.5041.00
157_R160_E1.4611.00
68_L72_P1.4461.00
35_G38_F1.4381.00
24_L28_Y1.4361.00
41_S44_F1.4171.00
28_Y32_Y1.4041.00
12_Q16_F1.3851.00
125_F130_T1.3831.00
36_P40_K1.3501.00
74_A148_M1.3491.00
179_F186_I1.3481.00
30_L242_A1.3331.00
47_S50_S1.3241.00
129_Y219_A1.3111.00
188_S192_T1.3081.00
78_S149_Q1.2941.00
152_F178_V1.2891.00
126_Y129_Y1.2861.00
210_Y218_N1.2831.00
148_M189_A1.2831.00
79_R157_R1.2721.00
126_Y130_T1.2661.00
66_T193_S1.2631.00
58_A221_V1.2591.00
158_S161_I1.2531.00
201_F205_V1.2471.00
157_R161_I1.2331.00
247_F250_I1.2141.00
55_S222_A1.1991.00
220_Y225_Y1.1991.00
71_T186_I1.1971.00
163_A177_V1.1931.00
127_Y130_T1.1841.00
109_S122_G1.1831.00
201_F227_Y1.1801.00
208_A219_A1.1771.00
203_S207_V1.1761.00
135_A207_V1.1701.00
61_L64_V1.1621.00
229_E233_Y1.1551.00
221_V224_V1.1511.00
54_L57_F1.1501.00
64_V68_L1.1491.00
75_Y152_F1.1461.00
108_D131_G1.1411.00
84_I87_T1.1291.00
125_F129_Y1.1201.00
169_S173_V1.1141.00
124_I127_Y1.1121.00
183_I187_I1.1121.00
16_F20_L1.1001.00
141_S145_I1.1001.00
155_L181_L1.0991.00
41_S45_S1.0851.00
65_I133_L1.0851.00
39_V242_A1.0691.00
28_Y31_F1.0631.00
67_V186_I1.0621.00
204_V221_V1.0611.00
132_L204_V1.0541.00
225_Y240_A1.0521.00
84_I88_L1.0501.00
78_S152_F1.0371.00
61_L65_I1.0351.00
228_N232_T1.0301.00
29_L242_A1.0171.00
133_L137_I1.0071.00
181_L184_R0.9981.00
43_A49_L0.9901.00
148_M185_G0.9881.00
227_Y231_E0.9861.00
72_P76_Y0.9861.00
147_S189_A0.9761.00
52_I222_A0.9701.00
220_Y224_V0.9691.00
56_F60_A0.9661.00
62_S66_T0.9651.00
168_A173_V0.9631.00
62_S136_L0.9601.00
254_T258_V0.9591.00
75_Y174_F0.9561.00
38_F235_S0.9541.00
160_E170_E0.9481.00
173_V176_S0.9481.00
200_E203_S0.9421.00
47_S217_N0.9331.00
9_N13_A0.9271.00
74_A78_S0.9221.00
200_E204_V0.9181.00
75_Y170_E0.9171.00
210_Y219_A0.9161.00
168_A176_S0.9101.00
32_Y238_I0.9021.00
136_L197_A0.9011.00
62_S133_L0.8961.00
60_A64_V0.8941.00
76_Y82_N0.8891.00
229_E236_A0.8881.00
9_N12_Q0.8861.00
64_V190_G0.8831.00
104_L207_V0.8821.00
225_Y228_N0.8791.00
52_I56_F0.8771.00
57_F60_A0.8731.00
90_D146_R0.8721.00
183_I186_I0.8691.00
230_Y237_S0.8681.00
148_M182_S0.8611.00
8_F12_Q0.8601.00
104_L135_A0.8601.00
254_T257_I0.8601.00
19_S23_A0.8561.00
151_F182_S0.8521.00
182_S185_G0.8481.00
205_V224_V0.8451.00
135_A203_S0.8441.00
105_I109_S0.8371.00
70_F145_I0.8341.00
48_L240_A0.8331.00
173_V178_V0.8311.00
11_L15_S0.8301.00
144_Y148_M0.8301.00
38_F41_S0.8281.00
97_H139_V0.8261.00
175_T179_F0.8241.00
65_I68_L0.8191.00
101_G202_G0.8141.00
66_T70_F0.8121.00
74_A152_F0.8091.00
174_F179_F0.8061.00
193_S197_A0.8031.00
58_A136_L0.8031.00
250_I254_T0.8021.00
13_A16_F0.7881.00
236_A240_A0.7801.00
42_V243_T0.7791.00
70_F148_M0.7781.00
54_L129_Y0.7781.00
248_S252_I0.7731.00
90_D93_A0.7691.00
77_L86_E0.7641.00
53_G56_F0.7591.00
66_T140_S0.7561.00
61_L137_I0.7551.00
170_E174_F0.7541.00
21_L25_P0.7511.00
51_S54_L0.7471.00
127_Y210_Y0.7351.00
159_Y177_V0.7341.00
58_A129_Y0.7341.00
67_V148_M0.7301.00
129_Y133_L0.7301.00
63_I194_I0.7281.00
59_S63_I0.7261.00
131_G135_A0.7241.00
66_T144_Y0.7201.00
18_L22_L0.7181.00
74_A145_I0.7161.00
19_S22_L0.7141.00
174_F178_V0.7131.00
155_L182_S0.7131.00
77_L149_Q0.7121.00
46_S50_S0.7101.00
101_G206_I0.7091.00
157_R164_M0.7071.00
162_Y166_L0.7051.00
24_L27_L0.7001.00
100_V138_I0.6911.00
148_M152_F0.6901.00
29_L238_I0.6901.00
77_L85_I0.6861.00
229_E240_A0.6841.00
140_S193_S0.6831.00
80_H83_P0.6831.00
252_I256_R0.6821.00
130_T134_L0.6781.00
40_K43_A0.6771.00
186_I189_A0.6761.00
200_E221_V0.6761.00
69_I137_I0.6741.00
42_V236_A0.6731.00
162_Y165_S0.6721.00
29_L241_S0.6711.00
51_S222_A0.6691.00
223_S244_L0.6681.00
97_H202_G0.6671.00
63_I67_V0.6661.00
25_P29_L0.6651.00
73_L141_S0.6651.00
224_V227_Y0.6631.00
86_E146_R0.6591.00
234_F238_I0.6581.00
224_V228_N0.6581.00
128_T219_A0.6561.00
49_L52_I0.6551.00
208_A220_Y0.6531.00
140_S196_R0.6531.00
66_T197_A0.6521.00
249_L253_V0.6511.00
132_L208_A0.6511.00
76_Y80_H0.6501.00
109_S126_Y0.6491.00
46_S49_L0.6491.00
73_L89_V0.6461.00
10_T13_A0.6401.00
55_S198_I0.6401.00
31_F34_Y0.6401.00
10_T14_I0.6401.00
98_P206_I0.6401.00
185_G189_A0.6381.00
250_I257_I0.6371.00
8_F11_L0.6361.00
36_P39_V0.6321.00
55_S223_S0.6311.00
58_A132_L0.6301.00
106_F109_S0.6281.00
15_S19_S0.6271.00
178_V181_L0.6211.00
186_I190_G0.6181.00
132_L136_L0.6161.00
66_T137_I0.6101.00
169_S175_T0.6061.00
93_A142_P0.6011.00
89_V142_P0.6011.00
222_A244_L0.6001.00
173_V177_V0.5991.00
131_G207_V0.5931.00
204_V224_V0.5921.00
62_S137_I0.5891.00
33_G239_S0.5861.00
226_I240_A0.5831.00
58_A133_L0.5821.00
59_S198_I0.5791.00
105_I126_Y0.5791.00
195_A199_S0.5781.00
106_F122_G0.5731.00
236_A239_S0.5731.00
101_G105_I0.5701.00
187_I190_G0.5691.00
255_S258_V0.5681.00
75_Y178_V0.5671.00
175_T178_V0.5631.00
253_V256_R0.5631.00
247_F257_I0.5621.00
47_S220_Y0.5621.00
190_G193_S0.5621.00
74_A149_Q0.5611.00
47_S225_Y0.5581.00
63_I197_A0.5581.00
244_L248_S0.5581.00
136_L204_V0.5561.00
202_G206_I0.5551.00
226_I241_S0.5551.00
251_L255_S0.5541.00
30_L34_Y0.5531.00
45_S49_L0.5521.00
93_A143_I0.5511.00
69_I141_S0.5501.00
250_I253_V0.5491.00
14_I18_L0.5491.00
58_A62_S0.5491.00
147_S185_G0.5461.00
196_R199_S0.5441.00
178_V182_S0.5421.00
87_T91_V0.5411.00
238_I241_S0.5391.00
202_G205_V0.5371.00
39_V239_S0.5361.00
88_L92_P0.5331.00
104_L107_I0.5301.00
73_L76_Y0.5291.00
29_L33_G0.5271.00
223_S226_I0.5261.00
97_H101_G0.5251.00
79_R83_P0.5241.00
59_S197_A0.5201.00
161_I164_M0.5201.00
42_V240_A0.5191.00
128_T131_G0.5191.00
85_I89_V0.5171.00
67_V71_T0.5171.00
238_I242_A0.5171.00
54_L219_A0.5161.00
50_S57_F0.5151.00
229_E232_T0.5151.00
33_G242_A0.5141.00
197_A200_E0.5111.00
71_T152_F0.5091.00
40_K45_S0.5091.00
204_V208_A0.5071.00
155_L160_E0.5071.00
17_F21_L0.5021.00
139_V203_S0.5011.00
54_L221_V0.5011.00
136_L200_E0.5011.00
234_F237_S0.5001.00
75_Y79_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2onkC 2 0.9283 100 0.283 Contact Map
3d31C 2 0.9132 100 0.299 Contact Map
4tquM 1 0.9811 100 0.31 Contact Map
3rlfG 1 0.9321 100 0.384 Contact Map
3rlfF 1 0.9547 100 0.387 Contact Map
4tquN 1 0.9019 100 0.397 Contact Map
4ymuD 2 0.8 99.9 0.472 Contact Map
3tuiA 2 0.7698 99.9 0.519 Contact Map
3zdqA 2 0.3396 5 0.952 Contact Map
4mrsA 2 0.3509 4.8 0.952 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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