GREMLIN Database
Y1042 - UPF0201 protein SSO1042
UniProt: Q97Z89 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 145 (127)
Sequences: 159 (124)
Seq/√Len: 11.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
57_H126_L2.5320.87
6_V23_I2.5290.87
31_K68_S2.3280.82
130_T133_G2.1680.77
56_F96_L2.0800.74
99_V109_A2.0780.74
69_A98_F2.0700.74
19_V22_A1.9930.71
67_D98_F1.9800.70
8_A23_I1.9710.70
61_R66_L1.9490.69
65_I69_A1.9340.68
60_L66_L1.9060.67
67_D130_T1.8360.64
84_F112_F1.7320.59
20_L93_V1.7250.59
60_L69_A1.7100.58
11_R59_V1.7000.58
66_L133_G1.6910.57
4_V10_V1.6790.57
84_F98_F1.6620.56
4_V96_L1.6290.55
94_G126_L1.5970.53
70_R128_P1.5740.52
13_S97_S1.5350.50
87_H112_F1.5010.48
27_F112_F1.4710.47
45_L55_K1.4610.46
74_M124_D1.4350.45
105_S109_A1.4240.45
96_L127_A1.4040.44
66_L135_P1.3790.43
86_I96_L1.3770.43
5_M44_V1.3680.42
17_N21_S1.3590.42
47_A111_K1.3570.42
65_I98_F1.3510.41
66_L128_P1.3480.41
65_I70_R1.3470.41
23_I60_L1.3430.41
24_S96_L1.3240.40
23_I114_I1.2760.38
10_V94_G1.2650.37
26_F119_P1.2600.37
45_L103_K1.2590.37
52_S86_I1.2520.37
33_N79_G1.2470.37
10_V19_V1.2340.36
67_D133_G1.2310.36
19_V91_A1.2090.35
20_L118_N1.1900.34
118_N121_E1.1860.34
24_S29_F1.1790.34
116_Y119_P1.1780.34
22_A79_G1.1690.33
132_H136_L1.1680.33
68_S112_F1.1560.33
8_A56_F1.1530.32
68_S97_S1.1280.31
7_V74_M1.1020.30
90_A108_G1.0940.30
63_E96_L1.0880.30
30_E118_N1.0800.29
99_V105_S1.0730.29
15_D18_K1.0650.29
66_L130_T1.0600.29
108_G114_I1.0550.28
33_N76_G1.0490.28
51_K56_F1.0320.28
57_H125_W1.0200.27
82_I119_P1.0180.27
85_M111_K1.0150.27
87_H105_S1.0080.27
51_K73_L0.9930.26
65_I97_S0.9870.26
26_F43_L0.9840.26
92_A96_L0.9830.26
16_V37_E0.9660.25
22_A27_F0.9610.25
27_F91_A0.9560.25
26_F99_V0.9410.24
57_H61_R0.9390.24
63_E66_L0.9350.24
32_M35_R0.9240.24
103_K115_E0.9220.24
59_V62_N0.9160.23
77_I125_W0.9080.23
19_V110_I0.8930.23
77_I122_I0.8900.22
78_E81_T0.8870.22
72_Y94_G0.8830.22
60_L65_I0.8720.22
4_V78_E0.8710.22
5_M117_Q0.8690.22
35_R47_A0.8610.22
90_A105_S0.8580.21
67_D76_G0.8520.21
51_K54_L0.8460.21
7_V43_L0.8460.21
6_V43_L0.8410.21
64_R102_D0.8280.20
47_A52_S0.8220.20
55_K77_I0.8210.20
70_R124_D0.8200.20
27_F84_F0.8170.20
91_A110_I0.8150.20
27_F90_A0.8140.20
90_A95_V0.8140.20
94_G108_G0.8070.20
53_L125_W0.8050.20
8_A13_S0.7940.19
97_S109_A0.7870.19
128_P133_G0.7860.19
26_F126_L0.7830.19
57_H136_L0.7820.19
54_L96_L0.7810.19
75_K93_V0.7800.19
26_F62_N0.7800.19
58_R64_R0.7770.19
63_E95_V0.7620.18
84_F108_G0.7590.18
22_A91_A0.7570.18
11_R52_S0.7440.18
61_R70_R0.7350.18
10_V22_A0.7340.18
44_V79_G0.7270.17
57_H135_P0.7270.17
10_V34_T0.7260.17
36_K117_Q0.7240.17
53_L110_I0.7230.17
64_R121_E0.7200.17
112_F120_K0.7170.17
28_D68_S0.7150.17
25_N126_L0.7110.17
20_L24_S0.6980.17
98_F128_P0.6940.17
15_D20_L0.6840.16
116_Y122_I0.6830.16
104_E109_A0.6830.16
26_F132_H0.6780.16
71_K129_K0.6760.16
46_E81_T0.6710.16
13_S17_N0.6620.16
79_G92_A0.6550.16
60_L135_P0.6500.15
96_L134_V0.6480.15
55_K58_R0.6410.15
25_N85_M0.6330.15
52_S77_I0.6300.15
59_V63_E0.6260.15
26_F135_P0.6160.15
4_V32_M0.6120.15
6_V72_Y0.6060.14
99_V126_L0.6040.14
11_R26_F0.6040.14
16_V112_F0.6020.14
20_L34_T0.6020.14
23_I28_D0.6000.14
60_L97_S0.5900.14
19_V56_F0.5900.14
61_R128_P0.5900.14
76_G113_Y0.5840.14
53_L81_T0.5770.14
98_F130_T0.5740.14
18_K106_P0.5690.14
17_N115_E0.5670.13
73_L80_N0.5630.13
13_S65_I0.5630.13
55_K59_V0.5600.13
65_I128_P0.5580.13
21_S45_L0.5510.13
98_F127_A0.5500.13
33_N58_R0.5460.13
70_R130_T0.5440.13
11_R115_E0.5390.13
20_L32_M0.5380.13
38_G113_Y0.5380.13
63_E133_G0.5350.13
25_N32_M0.5320.13
124_D134_V0.5320.13
57_H124_D0.5300.13
28_D54_L0.5250.13
90_A93_V0.5250.13
67_D128_P0.5160.12
80_N123_V0.5110.12
23_I76_G0.5100.12
32_M75_K0.5070.12
38_G43_L0.5070.12
19_V100_D0.5060.12
105_S119_P0.5000.12
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2nwuA 2 0.9241 100 0.219 Contact Map
3d7aA 2 0.9241 100 0.274 Contact Map
3c9gA 2 0.8759 100 0.278 Contact Map
2pzzA 2 0.8897 100 0.313 Contact Map
2ogkA 4 0.8552 100 0.496 Contact Map
2wnyA 1 0.8276 100 0.528 Contact Map
2nrqA 1 0.8069 100 0.533 Contact Map
2fgcA 2 0.4828 21.8 0.947 Contact Map
1sflA 2 0.9448 8.9 0.955 Contact Map
4cu7A 1 0.7379 8.1 0.956 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0064 seconds.