GREMLIN Database
Q97Z60 - First ORF in transposon ISC1904
UniProt: Q97Z60 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 146 (132)
Sequences: 477 (298)
Seq/√Len: 25.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_V70_R4.1591.00
13_A31_L3.7591.00
70_R97_E3.5861.00
35_V72_V3.5551.00
56_F79_L2.9061.00
11_L101_I2.6950.99
63_I91_Y2.5990.99
88_E92_K2.5520.99
64_L94_H2.5080.99
44_D55_G2.4760.99
28_V41_V2.2460.98
30_Y74_A2.1620.97
11_L31_L2.1370.97
51_M85_E1.9950.95
11_L41_V1.9440.95
59_L68_V1.8990.94
84_F98_I1.8750.93
42_I55_G1.8450.93
28_V43_T1.6970.89
40_Q62_M1.6840.89
91_Y96_C1.6490.88
49_L82_F1.6030.87
8_K62_M1.5720.85
115_L119_L1.4880.82
91_Y123_S1.4790.82
25_V29_K1.4760.82
75_Y113_E1.4720.81
51_M121_S1.4370.80
60_L64_L1.4230.79
35_V38_Y1.4140.79
49_L83_G1.4100.78
72_V99_V1.3930.78
44_D74_A1.3450.75
9_V97_E1.3440.75
38_Y95_G1.3320.74
80_V87_L1.3250.74
29_K32_E1.3190.74
91_Y126_L1.3120.73
63_I71_V1.3120.73
62_M67_E1.3070.73
63_I68_V1.3030.73
72_V85_E1.2740.71
63_I96_C1.2350.68
121_S124_G1.2290.68
15_V24_L1.2130.67
82_F114_D1.2020.66
48_K79_L1.1980.66
95_G115_L1.1860.65
9_V72_V1.1850.65
10_I59_L1.1780.65
11_L35_V1.1440.62
111_L122_F1.1380.62
15_V20_Q1.1280.61
61_R93_A1.1030.59
51_M80_V1.1000.59
109_E113_E1.0970.59
20_Q23_D1.0900.59
74_A132_H1.0830.58
70_R99_V1.0820.58
120_V131_S1.0700.57
80_V84_F1.0650.57
29_K33_E1.0580.56
84_F100_V1.0530.56
50_N94_H1.0280.54
71_V98_I1.0270.54
86_I108_P0.9990.52
7_R96_C0.9900.51
12_Y15_V0.9890.51
37_E72_V0.9890.51
63_I73_V0.9760.50
64_L90_T0.9610.49
127_Y130_R0.9600.49
71_V137_V0.9570.49
34_Q99_V0.9530.49
34_Q102_N0.9490.48
44_D121_S0.9440.48
131_S137_V0.9300.47
10_I42_I0.9190.46
10_I28_V0.9100.45
23_D26_N0.9080.45
31_L101_I0.9050.45
73_V98_I0.9030.45
46_G117_S0.8980.44
7_R65_N0.8970.44
118_T128_G0.8940.44
9_V69_S0.8770.43
8_K69_S0.8610.42
26_N29_K0.8470.41
42_I59_L0.8430.41
19_T75_Y0.8280.39
34_Q101_I0.8280.39
39_D56_F0.8260.39
80_V117_S0.8200.39
75_Y107_T0.8140.38
56_F121_S0.8000.37
30_Y132_H0.7860.37
73_V97_E0.7730.36
30_Y102_N0.7700.35
106_K129_M0.7680.35
52_K125_K0.7550.34
100_V119_L0.7520.34
107_T132_H0.7460.34
26_N116_V0.7440.34
56_F80_V0.7420.34
87_L91_Y0.7390.33
82_F118_T0.7360.33
88_E105_D0.7350.33
16_S20_Q0.7270.33
60_L99_V0.7260.33
110_E122_F0.7250.32
25_V28_V0.7240.32
120_V124_G0.7160.32
57_L87_L0.7050.31
100_V108_P0.7000.31
64_L86_I0.6990.31
102_N106_K0.6920.30
125_K129_M0.6900.30
57_L89_E0.6900.30
52_K116_V0.6900.30
18_N66_N0.6840.30
46_G100_V0.6820.30
42_I71_V0.6820.30
7_R95_G0.6810.30
114_D128_G0.6770.29
71_V113_E0.6760.29
7_R110_E0.6760.29
111_L120_V0.6740.29
17_S26_N0.6690.29
92_K125_K0.6670.29
31_L96_C0.6670.29
105_D119_L0.6570.28
114_D118_T0.6530.28
50_N59_L0.6480.28
39_D72_V0.6420.27
135_E139_K0.6360.27
8_K39_D0.6350.27
30_Y117_S0.6350.27
17_S20_Q0.6330.27
34_Q70_R0.6330.27
83_G123_S0.6290.27
74_A120_V0.6290.27
71_V79_L0.6290.27
55_G73_V0.6230.26
115_L128_G0.6220.26
18_N21_K0.6190.26
28_V32_E0.6170.26
124_G129_M0.6170.26
58_K126_L0.6030.25
42_I57_L0.6000.25
88_E99_V0.5910.24
52_K94_H0.5890.24
82_F128_G0.5890.24
49_L110_E0.5860.24
8_K40_Q0.5860.24
54_K69_S0.5810.24
51_M57_L0.5790.24
51_M71_V0.5770.24
88_E98_I0.5760.24
39_D69_S0.5700.23
48_K56_F0.5670.23
112_V128_G0.5660.23
9_V46_G0.5630.23
87_L111_L0.5620.23
96_C110_E0.5600.23
80_V128_G0.5600.23
42_I62_M0.5600.23
61_R89_E0.5580.23
35_V74_A0.5570.23
11_L102_N0.5540.22
111_L114_D0.5520.22
67_E107_T0.5500.22
72_V101_I0.5500.22
82_F111_L0.5490.22
90_T93_A0.5480.22
33_E37_E0.5470.22
76_P119_L0.5450.22
22_D26_N0.5440.22
124_G128_G0.5420.22
59_L138_K0.5390.22
132_H138_K0.5350.22
113_E124_G0.5350.22
21_K97_E0.5330.21
46_G97_E0.5310.21
13_A24_L0.5300.21
125_K128_G0.5290.21
22_D58_K0.5220.21
45_I53_R0.5210.21
101_I108_P0.5200.21
76_P115_L0.5160.21
20_Q47_S0.5140.21
74_A124_G0.5130.20
53_R80_V0.5120.20
25_V43_T0.5110.20
38_Y53_R0.5060.20
41_V64_L0.5050.20
124_G131_S0.5020.20
22_D118_T0.5000.20
56_F69_S0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ilxA 2 0.9521 99.9 0.547 Contact Map
3lhkA 2 0.9658 99.9 0.554 Contact Map
3g13A 2 0.9658 99.8 0.648 Contact Map
3bvpA 4 0.8562 99.8 0.657 Contact Map
3guvA 2 0.9315 99.8 0.663 Contact Map
4bqqA 2 0.911 99.8 0.671 Contact Map
2mhcA 1 0.7397 99.8 0.675 Contact Map
2gm5A 4 0.8356 99.7 0.679 Contact Map
1gdtA 2 0.911 99.7 0.679 Contact Map
3pkzA 4 0.774 99.7 0.692 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0058 seconds.