GREMLIN Database
Q97Z29 - Uncharacterized protein
UniProt: Q97Z29 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 154 (128)
Sequences: 2257 (1597)
Seq/√Len: 141.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
63_S66_D3.6621.00
88_D117_K3.1351.00
67_V71_V2.3951.00
39_M58_K2.3891.00
116_E120_K2.3241.00
62_P66_D2.2621.00
44_N58_K2.2601.00
17_N44_N2.2351.00
65_L92_E2.2111.00
37_F135_Y2.1951.00
65_L89_Q2.1581.00
15_Y73_I2.1261.00
36_K40_D2.0421.00
97_V100_V1.9731.00
61_Y68_P1.9401.00
84_P111_N1.9251.00
87_V103_I1.8521.00
23_F35_P1.8291.00
107_E133_K1.8091.00
26_D29_K1.8051.00
48_V67_V1.8021.00
44_N69_D1.7201.00
9_K13_L1.6871.00
91_L121_A1.6461.00
10_E14_K1.5551.00
17_N69_D1.4961.00
46_I69_D1.4771.00
115_A127_Q1.4721.00
70_K101_K1.4721.00
87_V114_A1.4621.00
134_E137_K1.4411.00
83_V105_M1.4161.00
85_K88_D1.4071.00
91_L117_K1.3691.00
84_P117_K1.3551.00
11_V102_V1.3531.00
25_K52_A1.3481.00
55_I60_S1.3361.00
54_E59_K1.3031.00
64_I97_V1.2521.00
115_A119_R1.2401.00
15_Y102_V1.2301.00
110_R128_D1.2301.00
129_R134_E1.2301.00
17_N46_I1.2171.00
76_I105_M1.1991.00
78_R82_E1.1951.00
88_D92_E1.1751.00
82_E85_K1.1620.99
102_V124_V1.1530.99
52_A55_I1.1480.99
79_P82_E1.1220.99
117_K121_A1.1180.99
63_S89_Q1.1170.99
52_A60_S1.1170.99
112_D127_Q1.1120.99
87_V118_A1.1110.99
41_H135_Y1.0980.99
20_T45_V1.0970.99
112_D116_E1.0840.99
84_P88_D1.0670.99
116_E119_R1.0610.99
33_Q132_Y1.0560.99
115_A125_V1.0410.99
73_I131_M1.0240.99
18_I73_I1.0180.99
21_V74_V1.0080.99
53_S62_P1.0040.99
71_V97_V0.9920.98
15_Y72_E0.9880.98
132_Y136_M0.9880.98
77_F106_Q0.9840.98
39_M56_L0.9760.98
20_T35_P0.9750.98
91_L123_L0.9650.98
21_V86_I0.9650.98
110_R127_Q0.9590.98
73_I102_V0.9520.98
23_F55_I0.9380.98
118_A125_V0.9330.98
32_F36_K0.9320.98
107_E134_E0.9260.97
24_S31_A0.9250.97
29_K79_P0.9230.97
30_A34_V0.9160.97
30_A33_Q0.9060.97
103_I118_A0.8900.97
83_V109_I0.8890.97
75_E131_M0.8780.97
47_P60_S0.8740.96
84_P113_E0.8730.96
32_F56_L0.8690.96
85_K89_Q0.8680.96
118_A123_L0.8600.96
37_F132_Y0.8590.96
7_V124_V0.8570.96
87_V117_K0.8560.96
28_S33_Q0.8400.96
10_E124_V0.8310.95
11_V126_I0.8270.95
47_P59_K0.8220.95
46_I67_V0.8100.95
21_V90_V0.8090.95
61_Y67_V0.8010.94
76_I86_I0.7800.93
38_L45_V0.7760.93
100_V123_L0.7710.93
54_E57_G0.7640.93
25_K55_I0.7630.93
113_E116_E0.7520.92
49_N52_A0.7510.92
76_I103_I0.7480.92
91_L100_V0.7470.92
98_G123_L0.7460.92
34_V77_F0.7420.92
26_D51_S0.7210.90
76_I83_V0.7210.90
74_V90_V0.7140.90
18_I131_M0.7060.89
33_Q36_K0.7040.89
35_P58_K0.6970.89
25_K51_S0.6940.89
18_I43_Y0.6910.88
34_V106_Q0.6720.87
8_I129_R0.6700.87
8_I12_L0.6660.87
90_V123_L0.6650.86
10_E13_L0.6580.86
37_F136_M0.6560.86
83_V111_N0.6540.86
27_P32_F0.6530.85
49_N60_S0.6510.85
49_N62_P0.6490.85
111_N114_A0.6420.84
112_D115_A0.6410.84
31_A35_P0.6400.84
105_M125_V0.6310.83
35_P45_V0.6290.83
107_E132_Y0.6260.83
27_P36_K0.6260.83
46_I61_Y0.6230.83
88_D113_E0.6220.83
35_P38_L0.6180.82
24_S52_A0.6130.82
53_S59_K0.6100.81
111_N117_K0.6090.81
23_F45_V0.6090.81
37_F41_H0.6080.81
39_M44_N0.6080.81
67_V97_V0.6070.81
104_W114_A0.6030.81
90_V100_V0.6010.80
54_E60_S0.6000.80
49_N79_P0.5930.80
14_K101_K0.5930.80
101_K124_V0.5920.79
24_S86_I0.5890.79
35_P39_M0.5890.79
78_R86_I0.5850.79
106_Q109_I0.5830.78
9_K138_K0.5810.78
80_S109_I0.5810.78
91_L98_G0.5800.78
88_D91_L0.5780.78
33_Q37_F0.5660.76
7_V14_K0.5650.76
34_V75_E0.5600.76
25_K49_N0.5580.75
29_K109_I0.5560.75
87_V91_L0.5560.75
23_F60_S0.5480.74
6_E9_K0.5480.74
75_E106_Q0.5420.73
86_I89_Q0.5410.73
6_E10_E0.5390.73
52_A62_P0.5310.72
20_T23_F0.5270.71
88_D120_K0.5270.71
70_K97_V0.5250.71
45_V58_K0.5210.70
7_V10_E0.5200.70
23_F39_M0.5180.70
30_A77_F0.5180.70
64_I90_V0.5160.70
38_L131_M0.5130.69
24_S49_N0.5110.69
39_M45_V0.5090.69
69_D97_V0.5040.68
35_P56_L0.5000.67
80_S110_R0.5000.67
72_E101_K0.5000.67
19_A71_V0.5000.67
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ff4A 1 0.7857 100 0.423 Contact Map
2csuA 2 0.9156 100 0.44 Contact Map
1iukA 1 0.8701 99.9 0.526 Contact Map
2duwA 1 0.8766 99.9 0.534 Contact Map
1y81A 1 0.7532 99.9 0.553 Contact Map
2d59A 1 0.8896 99.9 0.563 Contact Map
3pffA 2 0.8831 99.9 0.567 Contact Map
3mwdB 1 0.8896 99.8 0.602 Contact Map
2fp4A 1 0.9416 99.8 0.604 Contact Map
2yv1A 1 0.8896 99.8 0.613 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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