GREMLIN Database
Q97Z17 - Uncharacterized protein
UniProt: Q97Z17 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 143 (135)
Sequences: 713 (370)
Seq/√Len: 31.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
100_K123_D4.7811.00
131_F140_T3.9421.00
13_V40_L3.9201.00
21_L49_A3.7981.00
30_G128_V3.7031.00
105_S125_V3.6751.00
77_K80_E2.9241.00
32_A99_V2.5041.00
37_E100_K2.4050.99
8_K37_E2.3740.99
135_A139_T2.3540.99
29_S96_I2.2740.99
15_S20_K2.1310.98
84_P88_Q2.0960.98
25_G42_F1.9500.97
22_M75_M1.8650.96
102_F126_V1.8270.96
93_A99_V1.8110.96
25_G40_L1.7630.95
25_G90_V1.7560.95
13_V24_V1.7230.94
10_S131_F1.7200.94
39_N102_F1.6680.93
108_M118_L1.6630.93
91_Q95_E1.6600.93
61_P72_P1.6310.92
131_F139_T1.6240.92
40_L101_V1.5970.91
131_F135_A1.5640.91
113_I118_L1.5280.90
42_F50_I1.5160.89
29_S93_A1.5010.89
27_L128_V1.5000.89
122_V125_V1.4910.88
9_L36_Y1.4080.85
83_Y106_T1.4010.85
73_I76_Q1.3640.83
72_P76_Q1.3420.82
100_K134_R1.3360.82
72_P75_M1.3240.81
7_K36_Y1.3070.81
36_Y138_G1.2940.80
27_L132_L1.2760.79
14_F19_D1.2340.77
11_I143_I1.2240.76
32_A129_A1.1950.74
29_S89_L1.1880.74
94_K121_F1.1770.73
47_L103_A1.1620.72
9_L27_L1.1570.72
8_K136_E1.1490.71
11_I27_L1.1460.71
61_P65_K1.1310.70
26_I89_L1.1300.70
88_Q92_Q1.1080.68
12_I27_L1.0780.66
10_S140_T1.0780.66
94_K123_D1.0770.66
107_T110_F1.0100.61
26_I75_M1.0070.61
67_Y72_P1.0060.61
110_F125_V0.9760.58
36_Y139_T0.9630.57
39_N100_K0.9580.57
13_V42_F0.9530.57
18_I76_Q0.9390.55
75_M110_F0.9370.55
85_M88_Q0.9310.55
128_V138_G0.9090.53
39_N131_F0.9090.53
14_F23_P0.8940.52
61_P64_D0.8820.51
20_K45_W0.8750.50
53_R95_E0.8740.50
8_K134_R0.8540.48
14_F20_K0.8500.48
50_I119_A0.8480.48
127_G130_T0.8470.48
105_S127_G0.8470.48
66_N72_P0.8430.48
39_N134_R0.8260.46
61_P122_V0.8230.46
84_P92_Q0.8190.46
59_Q115_R0.8150.45
52_K80_E0.8150.45
12_I52_K0.8100.45
52_K120_E0.8010.44
7_K138_G0.7850.43
51_T113_I0.7760.42
65_K86_W0.7760.42
66_N71_G0.7740.42
12_I43_T0.7670.41
97_G111_F0.7660.41
47_L111_F0.7620.41
19_D45_W0.7540.40
30_G129_A0.7510.40
51_T143_I0.7510.40
9_L139_T0.7490.40
47_L109_E0.7470.40
16_G26_I0.7390.39
56_N59_Q0.7350.39
29_S92_Q0.7340.39
16_G19_D0.7320.39
27_L36_Y0.7310.39
102_F135_A0.7270.38
72_P90_V0.7210.38
34_S134_R0.7170.38
70_M80_E0.7090.37
18_I67_Y0.6990.36
91_Q96_I0.6990.36
10_S138_G0.6970.36
88_Q135_A0.6920.36
91_Q116_E0.6910.36
17_T66_N0.6850.35
96_I130_T0.6820.35
22_M89_L0.6790.35
34_S40_L0.6770.35
91_Q94_K0.6700.34
102_F134_R0.6700.34
82_K106_T0.6680.34
32_A93_A0.6660.34
8_K84_P0.6660.34
65_K69_Q0.6620.33
47_L108_M0.6580.33
33_A127_G0.6530.33
105_S109_E0.6490.32
68_E72_P0.6480.32
70_M73_I0.6450.32
54_S111_F0.6370.32
102_F130_T0.6370.32
76_Q85_M0.6360.32
40_L90_V0.6340.31
14_F43_T0.6340.31
17_T63_I0.6290.31
44_F107_T0.6280.31
21_L86_W0.6260.31
9_L138_G0.6230.31
54_S58_Q0.6220.31
37_E126_V0.6190.30
32_A96_I0.6180.30
17_T45_W0.6170.30
7_K80_E0.6130.30
102_F132_L0.6060.29
28_T43_T0.6020.29
49_A101_V0.5980.29
13_V27_L0.5940.29
67_Y85_M0.5910.28
20_K23_P0.5910.28
108_M126_V0.5900.28
56_N60_P0.5850.28
41_F106_T0.5850.28
88_Q95_E0.5810.28
67_Y70_M0.5770.28
89_L107_T0.5730.27
22_M49_A0.5710.27
46_G103_A0.5710.27
83_Y110_F0.5710.27
49_A94_K0.5710.27
14_F22_M0.5690.27
101_V143_I0.5680.27
62_Q69_Q0.5660.27
16_G34_S0.5640.27
26_I143_I0.5620.27
81_M110_F0.5620.27
57_S80_E0.5620.27
33_A129_A0.5570.26
22_M44_F0.5560.26
101_V122_V0.5510.26
107_T117_D0.5460.26
8_K36_Y0.5390.25
84_P105_S0.5390.25
57_S100_K0.5390.25
30_G45_W0.5370.25
24_V40_L0.5360.25
55_L143_I0.5360.25
56_N91_Q0.5350.25
63_I66_N0.5340.25
36_Y132_L0.5340.25
51_T117_D0.5310.25
45_W71_G0.5290.25
82_K105_S0.5260.24
23_P71_G0.5250.24
25_G50_I0.5250.24
23_P128_V0.5240.24
38_V41_F0.5230.24
27_L30_G0.5180.24
64_D70_M0.5180.24
18_I22_M0.5180.24
49_A122_V0.5160.24
29_S129_A0.5160.24
96_I101_V0.5160.24
58_Q103_A0.5160.24
29_S32_A0.5150.24
9_L97_G0.5150.24
42_F119_A0.5140.24
45_W111_F0.5120.24
88_Q138_G0.5090.23
17_T64_D0.5070.23
17_T68_E0.5020.23
37_E130_T0.5010.23
78_M128_V0.5000.23
87_H114_K0.5000.23
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pnxA 4 0.972 100 0.335 Contact Map
2qs7A 3 0.965 100 0.341 Contact Map
3mc3A 3 0.7343 99.8 0.649 Contact Map
1jx7A 5 0.7762 99.5 0.726 Contact Map
1l1sA 3 0.7413 99.4 0.738 Contact Map
2hy5B 1 0.7902 99.3 0.745 Contact Map
2d1pB 1 0.7902 99 0.781 Contact Map
2pd2A 3 0.7133 98.9 0.79 Contact Map
2hy5A 2 0.7832 98.8 0.799 Contact Map
2fb6A 3 0.7692 98.6 0.808 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.006 seconds.