GREMLIN Database
Q97Z10 - Uncharacterized protein
UniProt: Q97Z10 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 220 (199)
Sequences: 5369 (4058)
Seq/√Len: 287.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
110_N139_K3.8891.00
28_D63_Y3.7611.00
83_I115_L3.6761.00
117_D141_T3.0861.00
115_L118_K2.8901.00
202_E207_K2.8871.00
86_V121_L2.8711.00
197_N200_Y2.8031.00
67_L92_G2.7031.00
172_R203_D2.5901.00
110_N140_Y2.5481.00
66_K90_I2.5031.00
206_Y210_I2.3411.00
203_D207_K2.1901.00
117_D140_Y2.1531.00
34_R65_L2.1531.00
171_P203_D2.1191.00
68_G85_Q2.0981.00
102_F108_S2.0361.00
51_G84_R1.9851.00
171_P200_Y1.9461.00
87_D119_R1.8611.00
81_E84_R1.8541.00
115_L119_R1.8381.00
57_L66_K1.8361.00
83_I87_D1.8111.00
114_E118_K1.7991.00
25_L29_E1.7731.00
105_L135_W1.7501.00
65_L91_I1.7301.00
203_D211_E1.7141.00
84_R88_R1.6671.00
145_V212_L1.6071.00
120_G143_P1.6001.00
200_Y203_D1.5901.00
55_Q59_G1.5621.00
82_L112_V1.5561.00
86_V119_R1.5331.00
27_E35_I1.5001.00
110_N114_E1.4411.00
114_E140_Y1.4341.00
82_L93_V1.4341.00
120_G141_T1.3971.00
85_Q90_I1.3961.00
83_I119_R1.3771.00
79_Q115_L1.3411.00
54_Q58_W1.3391.00
67_L213_L1.3391.00
33_K206_Y1.3361.00
117_D142_F1.3281.00
37_L64_T1.3261.00
137_L144_V1.3241.00
83_I118_K1.2971.00
53_Y66_K1.2941.00
175_I208_N1.2821.00
113_Y136_L1.2591.00
175_I212_L1.2501.00
93_V116_I1.2451.00
74_C77_P1.2371.00
54_Q90_I1.2061.00
23_P35_I1.2011.00
203_D208_N1.1881.00
198_H202_E1.1781.00
116_I123_L1.1661.00
207_K210_I1.1631.00
126_Y179_D1.1621.00
120_G214_N1.1601.00
82_L116_I1.1591.00
209_A213_L1.1511.00
128_P146_L1.1431.00
52_F55_Q1.1431.00
19_Y22_E1.1421.00
107_S110_N1.1361.00
202_E206_Y1.1341.00
124_V147_I1.1301.00
143_P212_L1.1291.00
24_K60_R1.1211.00
111_F114_E1.1141.00
102_F109_L1.1091.00
175_I209_A1.1071.00
187_L190_S1.1061.00
68_G90_I1.1031.00
24_K28_D1.1031.00
47_C81_E1.1001.00
159_Y212_L1.0791.00
34_R62_D1.0771.00
22_E25_L1.0681.00
47_C51_G1.0531.00
21_E59_G1.0521.00
201_N205_A1.0491.00
192_K201_N1.0381.00
36_L65_L1.0371.00
210_I214_N1.0341.00
189_Q192_K1.0151.00
117_D120_G1.0141.00
189_Q193_L1.0061.00
26_T29_E1.0021.00
137_L157_R1.0021.00
185_L189_Q1.0011.00
79_Q111_F1.0011.00
127_D130_L1.0001.00
137_L158_V0.9991.00
105_L130_L0.9991.00
24_K63_Y0.9961.00
14_I17_Y0.9831.00
110_N113_Y0.9831.00
159_Y173_R0.9791.00
43_Y77_P0.9781.00
54_Q88_R0.9721.00
20_T59_G0.9721.00
113_Y123_L0.9711.00
52_F56_Y0.9711.00
76_V80_V0.9691.00
147_I161_V0.9651.00
199_G207_K0.9621.00
198_H201_N0.9601.00
27_E63_Y0.9591.00
47_C84_R0.9521.00
143_P159_Y0.9501.00
80_V83_I0.9501.00
135_W138_D0.9471.00
109_L113_Y0.9341.00
114_E117_D0.9311.00
36_L67_L0.9231.00
159_Y211_E0.9191.00
199_G203_D0.9181.00
55_Q58_W0.9181.00
75_R79_Q0.9071.00
21_E25_L0.9061.00
188_I192_K0.9011.00
160_Y169_I0.9011.00
82_L119_R0.9001.00
93_V123_L0.8981.00
170_D200_Y0.8981.00
122_I145_V0.8971.00
195_I201_N0.8921.00
172_R211_E0.8831.00
107_S139_K0.8741.00
186_N189_Q0.8711.00
94_V148_N0.8691.00
113_Y142_F0.8691.00
145_V175_I0.8651.00
102_F106_H0.8571.00
113_Y140_Y0.8511.00
191_A205_A0.8381.00
70_Y78_P0.8371.00
77_P80_V0.8361.00
25_L28_D0.8351.00
78_P112_V0.8341.00
29_E185_L0.8341.00
26_T180_A0.8241.00
124_V213_L0.8161.00
57_L64_T0.8111.00
70_Y112_V0.8101.00
124_V145_V0.8101.00
35_I64_T0.8080.99
128_P158_V0.8040.99
161_V177_G0.7990.99
38_N67_L0.7990.99
86_V115_L0.7920.99
112_V116_I0.7840.99
79_Q83_I0.7840.99
56_Y64_T0.7830.99
75_R78_P0.7820.99
67_L145_V0.7790.99
81_E85_Q0.7780.99
188_I205_A0.7780.99
36_L213_L0.7750.99
122_I212_L0.7730.99
186_N190_S0.7710.99
148_N179_D0.7670.99
192_K205_A0.7560.99
94_V126_Y0.7560.99
196_K200_Y0.7540.99
51_G81_E0.7490.99
146_L158_V0.7460.99
133_L146_L0.7410.99
95_L123_L0.7320.99
171_P204_V0.7310.99
82_L86_V0.7300.99
60_R63_Y0.7300.99
197_N201_N0.7290.99
21_E60_R0.7280.99
67_L124_V0.7230.99
164_H182_Y0.7140.99
185_L188_I0.7140.99
70_Y93_V0.7140.99
105_L132_E0.7140.99
149_S165_S0.7130.99
143_P211_E0.7110.99
72_P112_V0.7100.99
131_D137_L0.7090.99
27_E32_I0.7070.99
26_T30_I0.7000.99
44_S48_C0.6970.98
61_K64_T0.6950.98
134_R155_N0.6910.98
108_S111_F0.6910.98
207_K211_E0.6830.98
22_E26_T0.6800.98
51_G55_Q0.6800.98
94_V179_D0.6790.98
135_W139_K0.6780.98
38_N124_V0.6760.98
95_L125_L0.6720.98
98_K101_N0.6720.98
160_Y174_S0.6670.98
78_P82_L0.6640.98
95_L102_F0.6640.98
34_R210_I0.6560.98
196_K201_N0.6560.98
143_P173_R0.6560.98
96_S99_H0.6500.98
57_L90_I0.6480.98
82_L115_L0.6470.98
68_G82_L0.6460.98
196_K204_V0.6460.98
149_S162_V0.6440.97
27_E64_T0.6420.97
94_V124_V0.6380.97
67_L147_I0.6370.97
137_L155_N0.6360.97
148_N153_V0.6320.97
50_D81_E0.6290.97
133_L137_L0.6280.97
85_Q88_R0.6250.97
94_V147_I0.6190.97
125_L146_L0.6190.97
53_Y57_L0.6170.97
129_S133_L0.6150.97
208_N211_E0.6150.97
138_D155_N0.6130.97
24_K27_E0.6090.97
58_W89_G0.6060.96
80_V115_L0.6030.96
159_Y208_N0.5960.96
20_T24_K0.5950.96
38_N148_N0.5950.96
23_P180_A0.5950.96
151_H154_D0.5910.96
71_N81_E0.5910.96
90_I93_V0.5900.96
122_I213_L0.5900.96
50_D54_Q0.5880.96
26_T184_S0.5840.96
131_D135_W0.5840.96
160_Y163_N0.5810.95
155_N160_Y0.5760.95
36_L92_G0.5740.95
136_L142_F0.5730.95
123_L144_V0.5710.95
56_Y59_G0.5710.95
38_N213_L0.5690.95
116_I119_R0.5680.95
74_C78_P0.5560.94
103_S127_D0.5560.94
57_L91_I0.5560.94
191_A201_N0.5510.94
42_K46_D0.5510.94
28_D62_D0.5500.94
48_C51_G0.5500.94
49_V52_F0.5480.94
86_V120_G0.5470.94
124_V161_V0.5460.94
70_Y82_L0.5450.94
68_G93_V0.5450.94
42_K45_C0.5440.94
132_E135_W0.5430.94
161_V179_D0.5430.94
206_Y209_A0.5400.93
38_N161_V0.5390.93
145_V213_L0.5380.93
105_L136_L0.5380.93
38_N179_D0.5340.93
72_P96_S0.5330.93
72_P109_L0.5320.93
155_N161_V0.5320.93
155_N169_I0.5310.93
111_F115_L0.5300.93
75_R112_V0.5250.92
156_E159_Y0.5240.92
19_Y25_L0.5240.92
93_V121_L0.5220.92
93_V112_V0.5220.92
86_V93_V0.5210.92
152_V166_S0.5190.92
30_I185_L0.5180.92
149_S153_V0.5160.92
91_I121_L0.5140.92
40_I69_I0.5140.92
33_K36_L0.5140.92
39_P49_V0.5140.92
54_Q57_L0.5140.92
95_L116_I0.5130.91
41_Y44_S0.5110.91
148_N154_D0.5090.91
18_N22_E0.5030.91
131_D136_L0.5000.90
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ofcA 4 0.9864 100 0.328 Contact Map
2hbvA 3 0.9727 100 0.331 Contact Map
3nurA 2 0.9636 100 0.332 Contact Map
3irsA 3 0.9818 100 0.34 Contact Map
2gwgA 2 0.9682 100 0.34 Contact Map
2f6kA 4 0.9636 100 0.35 Contact Map
4qrnA 2 0.9773 100 0.351 Contact Map
4lanA 2 0.9682 100 0.352 Contact Map
4l6dA 4 0.9773 100 0.361 Contact Map
2ffiA 1 0.9636 100 0.362 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0081 seconds.