GREMLIN Database
Q97YY2 - Sugar transport protein, hypothetical
UniProt: Q97YY2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 297 (254)
Sequences: 69986 (45662)
Seq/√Len: 2865.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
204_T208_T4.2251.00
73_K77_I3.1801.00
181_Y185_Q3.0051.00
39_S59_Y2.9991.00
196_D205_K2.9771.00
99_Q192_Y2.6861.00
192_Y210_T2.6611.00
195_A205_K2.5931.00
70_E73_K2.5621.00
201_N204_T2.5511.00
71_L254_Y2.5071.00
81_G165_I2.4871.00
85_T169_D2.4391.00
57_R60_L2.4301.00
183_A217_T2.3961.00
203_F207_L2.3591.00
83_L222_F2.3521.00
69_L73_K2.3371.00
249_E257_Q2.3081.00
57_R61_I2.2711.00
60_L64_Q2.2661.00
180_F218_I2.2461.00
202_A205_K2.2421.00
91_F206_F2.1331.00
102_L105_R2.1081.00
204_T207_L2.0931.00
200_A204_T2.0861.00
264_N267_L2.0721.00
98_N185_Q1.9711.00
176_F221_V1.9701.00
184_L214_L1.9641.00
191_L213_S1.8771.00
87_M222_F1.8761.00
195_A200_A1.8741.00
90_G176_F1.7701.00
79_T226_F1.7681.00
91_F214_L1.7661.00
37_Y41_T1.7661.00
196_D202_A1.7571.00
33_L37_Y1.7431.00
192_Y205_K1.7091.00
109_Y181_Y1.7061.00
70_E74_N1.7021.00
97_L177_M1.6651.00
91_F180_F1.6501.00
284_I288_K1.6131.00
77_I81_G1.6051.00
93_L177_M1.5991.00
254_Y258_E1.5821.00
36_V273_I1.5541.00
82_S229_T1.5441.00
61_I267_L1.5271.00
101_D105_R1.5191.00
192_Y196_D1.5081.00
94_A180_F1.4681.00
18_L22_I1.4521.00
30_F34_Y1.4361.00
104_G107_I1.4231.00
211_L218_I1.4231.00
98_N181_Y1.4091.00
176_F225_S1.3891.00
189_R192_Y1.3851.00
240_T248_T1.3701.00
55_G58_N1.3641.00
56_L60_L1.3641.00
233_F237_Y1.3531.00
242_G247_S1.3521.00
184_L210_T1.3491.00
78_W250_T1.3471.00
61_I64_Q1.3451.00
180_F221_V1.3311.00
99_Q189_R1.3311.00
220_F224_T1.3211.00
34_Y38_I1.3171.00
88_S92_V1.2991.00
67_Y70_E1.2721.00
86_M225_S1.2631.00
195_A209_I1.2561.00
189_R193_D1.2501.00
235_P239_L1.2441.00
91_F218_I1.2371.00
59_Y273_I1.2301.00
233_F256_Y1.2281.00
95_L184_L1.2241.00
167_T239_L1.2221.00
243_G247_S1.2171.00
201_N205_K1.2131.00
81_G84_L1.2121.00
131_W163_E1.2071.00
187_I213_S1.1951.00
75_T251_F1.1731.00
190_E193_D1.1661.00
258_E262_Y1.1531.00
249_E254_Y1.1521.00
22_I26_F1.1451.00
288_K291_R1.1321.00
84_L88_S1.1241.00
164_L236_I1.1221.00
107_I110_A1.1171.00
45_L53_Y1.1091.00
258_E264_N1.0941.00
165_I169_D1.0931.00
215_K219_A1.0901.00
35_S273_I1.0861.00
87_M218_I1.0861.00
180_F217_T1.0851.00
74_N77_I1.0851.00
63_F69_L1.0821.00
179_V221_V1.0821.00
13_S17_I1.0811.00
173_F177_M1.0781.00
107_I111_I1.0681.00
257_Q261_S1.0631.00
213_S216_R1.0561.00
95_L206_F1.0461.00
81_G85_T1.0441.00
12_F16_Y1.0381.00
15_F19_P1.0251.00
82_S86_M1.0241.00
285_I289_Y1.0241.00
98_N184_L1.0241.00
72_L251_F1.0181.00
92_V96_I1.0171.00
95_L202_A1.0121.00
82_S168_N1.0111.00
250_T253_V1.0111.00
192_Y202_A1.0071.00
232_N236_I1.0061.00
162_I166_A1.0031.00
200_A205_K1.0021.00
76_L80_I1.0011.00
105_R185_Q1.0001.00
236_I250_T0.9891.00
136_G139_N0.9821.00
168_N229_T0.9761.00
85_T165_I0.9751.00
249_E253_V0.9721.00
242_G248_T0.9701.00
42_N45_L0.9651.00
205_K208_T0.9651.00
183_A214_L0.9461.00
103_K106_S0.9451.00
232_N235_P0.9421.00
50_T53_Y0.9381.00
14_L18_L0.9351.00
127_W239_L0.9331.00
77_I162_I0.9261.00
141_L248_T0.9221.00
68_F271_W0.9161.00
34_Y37_Y0.9111.00
254_Y271_W0.9101.00
113_I178_T0.9101.00
215_K218_I0.9061.00
58_N266_A0.9001.00
17_I21_V0.8991.00
206_F211_L0.8981.00
80_I84_L0.8961.00
259_A268_A0.8951.00
237_Y253_V0.8941.00
82_S165_I0.8921.00
162_I165_I0.8921.00
94_A98_N0.8901.00
72_L76_L0.8891.00
77_I80_I0.8841.00
12_F15_F0.8831.00
41_T45_L0.8831.00
180_F214_L0.8821.00
207_L211_L0.8801.00
15_F18_L0.8761.00
44_S47_H0.8731.00
25_V29_V0.8731.00
124_I234_Y0.8731.00
38_I269_A0.8671.00
214_L217_T0.8651.00
137_M162_I0.8641.00
90_G177_M0.8631.00
40_F54_V0.8621.00
85_T88_S0.8561.00
167_T235_P0.8531.00
62_I274_I0.8521.00
84_L222_F0.8511.00
176_F180_F0.8491.00
65_Y69_L0.8441.00
61_I65_Y0.8421.00
191_L209_I0.8321.00
94_A177_M0.8301.00
106_S109_Y0.8281.00
94_A184_L0.8191.00
61_I264_N0.8151.00
225_S229_T0.8131.00
138_M141_L0.8131.00
120_G171_L0.8121.00
81_G169_D0.8091.00
86_M90_G0.8071.00
78_W168_N0.8061.00
38_I41_T0.8061.00
39_S43_L0.8051.00
254_Y257_Q0.8001.00
285_I288_K0.7931.00
205_K210_T0.7931.00
73_K76_L0.7911.00
30_F33_L0.7901.00
97_L109_Y0.7901.00
97_L108_F0.7891.00
38_I42_N0.7881.00
206_F210_T0.7811.00
35_S269_A0.7811.00
124_I238_V0.7781.00
187_I214_L0.7781.00
127_W167_T0.7751.00
40_F55_G0.7721.00
163_E167_T0.7711.00
256_Y260_F0.7681.00
258_E271_W0.7651.00
96_I102_L0.7651.00
180_F184_L0.7591.00
267_L271_W0.7511.00
243_G249_E0.7491.00
281_V285_I0.7491.00
279_V283_G0.7481.00
200_A208_T0.7471.00
113_I116_W0.7461.00
71_L74_N0.7451.00
269_A273_I0.7451.00
90_G180_F0.7431.00
202_A206_F0.7421.00
163_E239_L0.7401.00
79_T83_L0.7371.00
189_R196_D0.7341.00
134_P137_M0.7311.00
83_L226_F0.7271.00
87_M180_F0.7271.00
75_T252_I0.7261.00
86_M172_S0.7251.00
255_A271_W0.7251.00
19_P22_I0.7241.00
258_E267_L0.7211.00
139_N242_G0.7211.00
86_M176_F0.7191.00
42_N52_S0.7141.00
137_M140_R0.7131.00
215_K289_Y0.7121.00
236_I253_V0.7101.00
16_Y20_I0.7071.00
60_L63_F0.7051.00
27_L31_P0.7041.00
43_L47_H0.7041.00
54_V57_R0.6991.00
240_T249_E0.6981.00
62_I267_L0.6951.00
218_I221_V0.6941.00
269_A272_S0.6881.00
137_M141_L0.6881.00
83_L87_M0.6881.00
210_T213_S0.6861.00
35_S272_S0.6851.00
71_L251_F0.6841.00
45_L52_S0.6821.00
97_L181_Y0.6771.00
69_L72_L0.6741.00
286_V289_Y0.6741.00
101_D106_S0.6731.00
120_G234_Y0.6711.00
24_T28_F0.6661.00
56_L59_Y0.6641.00
164_L168_N0.6641.00
53_Y56_L0.6551.00
42_N53_Y0.6541.00
232_N250_T0.6531.00
93_L173_F0.6521.00
16_Y19_P0.6501.00
252_I275_S0.6491.00
41_T51_Y0.6481.00
78_W165_I0.6471.00
194_I198_D0.6391.00
253_V257_Q0.6391.00
55_G59_Y0.6351.00
116_W174_P0.6341.00
179_V217_T0.6331.00
123_S170_W0.6331.00
218_I222_F0.6321.00
251_F275_S0.6301.00
66_G70_E0.6291.00
164_L240_T0.6281.00
86_M229_T0.6281.00
102_L108_F0.6271.00
89_L169_D0.6241.00
78_W164_L0.6181.00
109_Y178_T0.6181.00
172_S225_S0.6171.00
201_N207_L0.6151.00
129_G134_P0.6121.00
172_S228_F0.6111.00
25_V28_F0.6061.00
58_N61_I0.6061.00
66_G69_L0.6051.00
116_W175_Y0.6041.00
104_G108_F0.6031.00
217_T221_V0.5961.00
75_T230_W0.5961.00
59_Y270_A0.5951.00
96_I100_T0.5931.00
194_I197_L0.5911.00
135_Y138_M0.5901.00
253_V256_Y0.5901.00
41_T53_Y0.5881.00
234_Y238_V0.5861.00
227_V231_N0.5851.00
112_L174_P0.5851.00
205_K209_I0.5841.00
127_W130_L0.5831.00
248_T252_I0.5831.00
39_S270_A0.5811.00
36_V40_F0.5811.00
83_L229_T0.5791.00
131_W138_M0.5781.00
62_I271_W0.5781.00
31_P35_S0.5771.00
135_Y140_R0.5761.00
121_F238_V0.5741.00
93_L112_L0.5711.00
120_G124_I0.5711.00
21_V25_V0.5701.00
118_F122_I0.5681.00
79_T229_T0.5681.00
20_I24_T0.5671.00
280_I284_I0.5641.00
133_D136_G0.5631.00
77_I165_I0.5631.00
187_I192_Y0.5631.00
86_M169_D0.5621.00
39_S273_I0.5601.00
255_A272_S0.5601.00
26_F30_F0.5601.00
130_L138_M0.5571.00
275_S279_V0.5561.00
94_A181_Y0.5531.00
41_T52_S0.5531.00
82_S169_D0.5511.00
219_A222_F0.5501.00
103_K107_I0.5501.00
50_T54_V0.5461.00
87_M91_F0.5451.00
108_F112_L0.5441.00
31_P38_I0.5431.00
228_F231_N0.5421.00
53_Y57_R0.5401.00
78_W82_S0.5391.00
101_D189_R0.5381.00
31_P39_S0.5381.00
284_I287_I0.5381.00
128_Q133_D0.5371.00
86_M173_F0.5361.00
267_L270_A0.5351.00
79_T230_W0.5351.00
278_F281_V0.5341.00
51_Y54_V0.5341.00
14_L17_I0.5341.00
77_I141_L0.5271.00
266_A269_A0.5261.00
168_N232_N0.5261.00
38_I43_L0.5261.00
18_L21_V0.5261.00
100_T202_A0.5211.00
87_M92_V0.5211.00
67_Y249_E0.5201.00
265_F268_A0.5201.00
93_L96_I0.5201.00
89_L173_F0.5191.00
265_F269_A0.5161.00
106_S110_A0.5151.00
31_P36_V0.5111.00
193_D196_D0.5111.00
29_V33_L0.5101.00
282_L286_V0.5091.00
110_A114_L0.5091.00
63_F274_I0.5081.00
97_L102_L0.5041.00
214_L218_I0.5041.00
243_G248_T0.5011.00
221_V225_S0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4tquM 1 0.9461 100 0.288 Contact Map
2onkC 2 0.8451 100 0.325 Contact Map
3rlfF 1 0.9394 100 0.326 Contact Map
3d31C 2 0.835 100 0.34 Contact Map
3rlfG 1 0.899 100 0.363 Contact Map
4tquN 1 0.8855 100 0.37 Contact Map
4ymuD 2 0.7205 99.9 0.515 Contact Map
3tuiA 2 0.7003 99.9 0.539 Contact Map
2a65A 2 0.798 14 0.947 Contact Map
2m20A 2 0.1246 6 0.955 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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