GREMLIN Database
Q97YV0 - Pyruvate synthase beta chain (Pyruvic-ferredoxin oxidoreductase beta chain) (PorB-1)
UniProt: Q97YV0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 300 (282)
Sequences: 1961 (964)
Seq/√Len: 57.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
123_D199_R5.2521.00
166_P237_F4.7811.00
180_A188_Y3.7041.00
125_L202_R3.5861.00
220_L223_D3.2611.00
197_Q242_G2.8981.00
164_P167_F2.8761.00
17_Y55_I2.6771.00
32_L100_W2.5771.00
224_I268_L2.5651.00
284_Q288_D2.5191.00
281_K285_E2.4281.00
84_V88_R2.4171.00
197_Q240_E2.3961.00
118_A169_I2.3781.00
145_T149_A2.3581.00
215_R270_G2.2191.00
117_A124_I2.1481.00
231_T260_K2.1401.00
35_A192_M2.1221.00
99_V124_I2.0471.00
209_P221_T2.0431.00
132_E162_K2.0101.00
263_A284_Q1.9961.00
128_C203_Y1.9681.00
193_R197_Q1.9311.00
114_V126_Y1.8501.00
118_A201_F1.8481.00
80_G99_V1.8410.99
187_D191_K1.8290.99
44_V87_L1.8270.99
89_M92_D1.8090.99
32_L129_Y1.7990.99
181_S225_A1.7340.99
261_P284_Q1.7280.99
130_D162_K1.7030.99
169_I203_Y1.6990.99
35_A100_W1.6970.99
227_L268_L1.6830.99
262_V283_I1.6800.99
166_P203_Y1.6590.99
263_A267_K1.6510.99
182_I222_I1.6340.99
180_A192_M1.6050.99
166_P177_V1.5890.98
261_P264_E1.5820.98
226_K230_E1.5800.98
229_V236_L1.5780.98
188_Y192_M1.5690.98
285_E289_E1.5670.98
88_R122_E1.5530.98
100_W129_Y1.5240.98
43_T96_I1.5220.98
243_E248_S1.5080.98
284_Q287_I1.5070.98
280_I286_E1.5060.98
282_G285_E1.4950.98
240_E252_T1.4920.98
195_A204_I1.4910.98
270_G274_Q1.4820.98
49_A70_H1.4680.97
267_K276_T1.4670.97
180_A206_L1.4630.97
118_A126_Y1.4630.97
262_V287_I1.4570.97
181_S229_V1.4460.97
288_D292_E1.4430.97
69_V79_I1.4430.97
106_T128_C1.4420.97
125_L196_K1.4230.97
35_A127_I1.4150.97
44_V97_V1.4080.97
28_I129_Y1.4050.97
230_E259_R1.4040.97
230_E260_K1.3960.97
282_G286_E1.3930.96
286_E290_M1.3710.96
162_K179_T1.3630.96
224_I269_Q1.3620.96
127_I204_I1.3540.96
131_N135_M1.3400.96
87_L97_V1.3250.95
121_N201_F1.3250.95
262_V284_Q1.3180.95
192_M204_I1.3170.95
232_G259_R1.3120.95
212_P215_R1.3070.95
212_P217_D1.3060.95
240_E243_E1.3060.95
130_D205_H1.2790.94
46_V80_G1.2730.94
287_I291_W1.2600.94
147_K286_E1.2590.94
86_S90_R1.2550.94
233_V265_Y1.2500.94
80_G97_V1.2470.94
46_V99_V1.2430.93
280_I287_I1.2430.93
181_S207_L1.2290.93
84_V122_E1.2280.93
285_E288_D1.2270.93
214_W217_D1.2170.93
35_A43_T1.2170.93
47_V68_V1.2110.93
231_T261_P1.2050.92
233_V262_V1.2030.92
31_E206_L1.1900.92
247_T250_S1.1770.91
33_D37_E1.1760.91
169_I177_V1.1660.91
167_F293_E1.1660.91
156_E159_R1.1590.91
83_I97_V1.1580.91
228_A265_Y1.1530.91
55_I129_Y1.1480.90
166_P179_T1.1470.90
194_K240_E1.1420.90
286_E289_E1.1420.90
46_V83_I1.1320.90
32_L55_I1.1310.90
180_A191_K1.1290.90
53_T57_G1.1280.90
198_I202_R1.1260.89
259_R288_D1.1220.89
182_I188_Y1.1210.89
49_A53_T1.1200.89
283_I287_I1.1190.89
39_L196_K1.1190.89
107_G144_L1.1180.89
81_S122_E1.1160.89
39_L98_A1.1070.89
289_E293_E1.1020.88
76_A99_V1.0850.88
49_A54_I1.0770.87
127_I192_M1.0660.87
147_K282_G1.0660.87
32_L64_S1.0650.87
128_C165_L1.0620.87
260_K264_E1.0600.86
243_E252_T1.0550.86
101_A126_Y1.0550.86
263_A276_T1.0510.86
280_I283_I1.0490.86
262_V266_L1.0440.86
71_S79_I1.0440.86
276_T280_I1.0420.85
283_I286_E1.0420.85
264_E267_K1.0260.85
22_A29_P1.0250.85
191_K238_E1.0250.85
242_G252_T1.0250.85
291_W294_I1.0210.84
160_E174_V1.0210.84
31_E208_S1.0110.84
216_F220_L1.0020.83
224_I227_L0.9930.83
263_A266_L0.9920.83
263_A277_E0.9830.82
244_F289_E0.9810.82
98_A196_K0.9790.82
60_N73_F0.9740.81
165_L203_Y0.9720.81
170_A237_F0.9710.81
243_E246_L0.9660.81
281_K289_E0.9620.81
39_L125_L0.9600.80
42_K96_I0.9550.80
53_T75_A0.9500.80
262_V272_F0.9480.80
170_A239_I0.9400.79
73_F109_I0.9380.79
280_I284_Q0.9350.79
49_A68_V0.9250.78
151_T154_T0.9090.77
178_A191_K0.9050.76
54_I70_H0.9030.76
146_P149_A0.8990.76
49_A75_A0.8980.76
141_R154_T0.8980.76
45_L100_W0.8960.76
54_I57_G0.8920.75
262_V288_D0.8910.75
27_P30_K0.8900.75
106_T126_Y0.8840.75
16_F56_M0.8830.75
96_I123_D0.8810.74
107_G205_H0.8790.74
121_N174_V0.8680.73
221_T225_A0.8640.73
219_K223_D0.8630.73
101_A106_T0.8560.72
283_I288_D0.8540.72
266_L272_F0.8540.72
236_L255_E0.8530.72
267_K280_I0.8520.72
286_E291_W0.8520.72
32_L36_L0.8490.72
36_L64_S0.8440.71
114_V169_I0.8420.71
227_L269_Q0.8410.71
49_A64_S0.8300.70
100_W127_I0.8300.70
179_T205_H0.8280.70
53_T70_H0.8250.69
145_T151_T0.8240.69
284_Q294_I0.8230.69
187_D238_E0.8220.69
194_K238_E0.8220.69
164_P290_M0.8190.69
266_L283_I0.8140.68
227_L230_E0.8130.68
22_A55_I0.8110.68
217_D220_L0.8070.68
223_D227_L0.8070.68
72_A75_A0.8060.68
242_G245_K0.8030.67
119_E141_R0.7980.67
216_F224_I0.7940.66
199_R242_G0.7940.66
87_L95_A0.7920.66
280_I291_W0.7880.66
230_E261_P0.7860.66
176_Y194_K0.7850.66
287_I294_I0.7840.65
96_I196_K0.7820.65
235_P251_K0.7820.65
167_F170_A0.7820.65
59_T62_M0.7810.65
165_L177_V0.7790.65
290_M294_I0.7780.65
30_K222_I0.7770.65
35_A188_Y0.7770.65
273_K277_E0.7730.64
115_S172_H0.7710.64
260_K273_K0.7690.64
168_I171_E0.7680.64
84_V97_V0.7660.64
107_G128_C0.7630.63
263_A273_K0.7550.63
85_R122_E0.7490.62
150_W274_Q0.7460.62
81_S120_R0.7420.61
89_M273_K0.7380.61
212_P216_F0.7370.61
44_V83_I0.7300.60
54_I80_G0.7280.60
161_V273_K0.7280.60
162_K233_V0.7270.60
132_E265_Y0.7260.60
107_G165_L0.7230.59
45_L64_S0.7220.59
198_I242_G0.7190.59
20_N29_P0.7180.59
216_F268_L0.7110.58
213_G217_D0.7110.58
179_T235_P0.7100.58
77_A113_A0.7060.57
133_A139_I0.7050.57
23_C26_C0.7050.57
87_L93_N0.7040.57
30_K34_V0.7030.57
170_A226_K0.7000.57
150_W275_L0.7000.57
290_M293_E0.7000.57
262_V267_K0.6960.56
88_R293_E0.6960.56
257_K270_G0.6900.56
80_G124_I0.6900.56
37_E189_E0.6880.55
71_S75_A0.6870.55
17_Y32_L0.6820.55
94_D123_D0.6800.55
161_V171_E0.6760.54
229_V265_Y0.6750.54
53_T64_S0.6730.54
243_E250_S0.6720.54
278_E285_E0.6690.53
279_Q292_E0.6670.53
14_P65_T0.6620.53
156_E160_E0.6610.52
260_K284_Q0.6590.52
276_T279_Q0.6580.52
139_I215_R0.6540.52
107_G143_G0.6520.51
56_M70_H0.6500.51
23_C210_C0.6480.51
268_L272_F0.6460.51
286_E294_I0.6450.51
281_K292_E0.6440.51
139_I150_W0.6420.50
262_V280_I0.6410.50
263_A288_D0.6390.50
175_P198_I0.6390.50
34_V37_E0.6380.50
58_D61_G0.6380.50
223_D226_K0.6370.50
53_T56_M0.6360.50
120_R174_V0.6360.50
51_C82_G0.6330.49
90_R122_E0.6330.49
42_K93_N0.6330.49
257_K273_K0.6320.49
267_K273_K0.6310.49
33_D146_P0.6280.49
183_A229_V0.6280.49
274_Q278_E0.6280.49
50_S75_A0.6270.49
48_P101_A0.6270.49
193_R199_R0.6260.49
227_L264_E0.6250.49
49_A73_F0.6250.49
20_N33_D0.6250.49
137_T210_C0.6240.48
186_Y190_A0.6240.48
264_E285_E0.6240.48
256_K259_R0.6200.48
57_G75_A0.6190.48
281_K284_Q0.6180.48
147_K161_V0.6170.48
144_L162_K0.6160.48
184_Y188_Y0.6150.47
39_L43_T0.6120.47
257_K288_D0.6110.47
87_L91_G0.6100.47
87_L90_R0.6090.47
246_L291_W0.6080.47
216_F273_K0.6080.47
207_L233_V0.6070.47
156_E286_E0.6060.46
179_T283_I0.6050.46
165_L205_H0.6030.46
148_G286_E0.6020.46
275_L283_I0.6020.46
161_V286_E0.5980.46
177_V203_Y0.5970.45
114_V118_A0.5960.45
47_V118_A0.5950.45
270_G273_K0.5950.45
235_P291_W0.5920.45
179_T237_F0.5890.45
266_L270_G0.5870.44
23_C51_C0.5870.44
118_A203_Y0.5870.44
47_V53_T0.5850.44
39_L96_I0.5830.44
220_L268_L0.5810.44
179_T262_V0.5760.43
118_A175_P0.5750.43
51_C210_C0.5740.43
36_L56_M0.5720.43
115_S163_K0.5710.43
130_D183_A0.5700.43
216_F227_L0.5690.42
288_D291_W0.5670.42
60_N70_H0.5670.42
183_A236_L0.5670.42
243_E247_T0.5600.41
181_S236_L0.5590.41
50_S68_V0.5570.41
162_K265_Y0.5560.41
124_I169_I0.5550.41
223_D245_K0.5550.41
227_L260_K0.5540.41
125_L192_M0.5530.41
239_I242_G0.5530.41
274_Q279_Q0.5510.41
28_I72_A0.5510.41
32_L52_T0.5500.40
52_T129_Y0.5500.40
59_T90_R0.5500.40
109_I138_G0.5490.40
34_V188_Y0.5490.40
108_D163_K0.5480.40
104_G210_C0.5480.40
176_Y238_E0.5470.40
268_L286_E0.5470.40
253_L294_I0.5460.40
239_I247_T0.5450.40
288_D294_I0.5440.40
185_I222_I0.5440.40
76_A124_I0.5430.40
276_T291_W0.5430.40
276_T285_E0.5430.40
188_Y206_L0.5410.39
20_N24_P0.5410.39
276_T284_Q0.5400.39
173_K198_I0.5380.39
46_V79_I0.5370.39
50_S157_G0.5370.39
223_D230_E0.5360.39
111_F168_I0.5360.39
247_T254_V0.5340.39
282_G287_I0.5320.39
276_T282_G0.5310.38
108_D136_N0.5290.38
239_I273_K0.5270.38
248_S252_T0.5240.38
266_L276_T0.5230.38
227_L235_P0.5220.37
13_M292_E0.5200.37
72_A203_Y0.5190.37
267_K287_I0.5120.36
15_K177_V0.5120.36
268_L292_E0.5100.36
139_I213_G0.5100.36
69_V126_Y0.5100.36
144_L266_L0.5090.36
32_L186_Y0.5080.36
178_A200_G0.5080.36
44_V67_P0.5070.36
184_Y189_E0.5070.36
84_V124_I0.5060.36
30_K33_D0.5050.36
42_K94_D0.5050.36
119_E172_H0.5040.36
88_R283_I0.5040.36
280_I290_M0.5030.36
70_H79_I0.5030.36
81_S84_V0.5020.35
209_P225_A0.5000.35
190_A193_R0.5000.35
27_P31_E0.5000.35
281_K286_E0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c42A 2 1 100 0.312 Contact Map
5c4iC 2 0.9733 100 0.475 Contact Map
4kgdA 4 0.81 100 0.747 Contact Map
1v5eA 4 0.8133 99.9 0.768 Contact Map
1umdA 2 0.82 99.9 0.78 Contact Map
1w85A 2 0.84 99.9 0.785 Contact Map
2panA 3 0.7967 99.9 0.786 Contact Map
1qs0A 2 0.82 99.9 0.792 Contact Map
4rjjA 5 0.71 99.9 0.797 Contact Map
1ybhA 4 0.7467 99.9 0.797 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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