GREMLIN Database
Q97YU7 - Pyruvate synthase gamma chain (Pyruvic-ferredoxin oxidoreductase gamma chain) (PorG-1)
UniProt: Q97YU7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 190 (172)
Sequences: 4506 (2986)
Seq/√Len: 227.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
160_E180_E4.2511.00
128_E132_I3.5641.00
97_L101_G3.2691.00
173_E177_E2.9361.00
38_E158_S2.7631.00
125_I128_E2.6841.00
102_F120_V2.6011.00
164_K176_A2.4841.00
160_E176_A2.4721.00
163_V179_V2.4641.00
132_I181_I2.4501.00
180_E184_K2.4341.00
161_E164_K2.4011.00
38_E155_S2.2831.00
78_D98_K2.2821.00
181_I184_K2.1571.00
99_E118_Y2.0601.00
155_S158_S2.0021.00
37_L161_E1.9761.00
156_L183_Y1.9661.00
15_A96_G1.9181.00
149_R183_Y1.7891.00
138_I174_L1.7731.00
177_E181_I1.7141.00
79_G147_L1.6881.00
41_Y67_P1.6661.00
156_L180_E1.6631.00
156_L160_E1.6491.00
157_H161_E1.6161.00
40_K65_D1.6131.00
35_M63_L1.5951.00
129_L185_E1.5861.00
148_A159_L1.5831.00
98_K101_G1.5801.00
173_E176_A1.5741.00
148_A183_Y1.5721.00
32_T44_S1.5231.00
142_A178_A1.5181.00
111_K115_K1.4991.00
145_G182_G1.4921.00
129_L181_I1.4891.00
12_I79_G1.4831.00
13_E62_R1.4521.00
105_L123_T1.4491.00
156_L179_V1.4431.00
37_L165_E1.4341.00
26_T167_F1.3881.00
167_F171_I1.3821.00
111_K114_W1.3811.00
160_E164_K1.3501.00
129_L142_A1.3341.00
81_A147_L1.3321.00
133_V181_I1.3131.00
176_A180_E1.3021.00
181_I185_E1.2761.00
157_H160_E1.2751.00
108_N125_I1.2631.00
130_G142_A1.2591.00
111_K117_E1.2571.00
133_V142_A1.2551.00
177_E180_E1.2411.00
107_T125_I1.2391.00
174_L177_E1.2341.00
107_T123_T1.2261.00
106_N127_K1.2161.00
80_V103_L1.2131.00
125_I185_E1.2071.00
126_A143_M1.2061.00
129_L132_I1.2051.00
79_G104_L1.1931.00
114_W117_E1.1831.00
146_A186_V1.1561.00
122_A150_I1.1441.00
133_V138_I1.1381.00
19_R84_D1.1351.00
85_V109_T1.1201.00
15_A60_F1.0971.00
103_L121_D1.0731.00
164_K172_G1.0711.00
108_N128_E1.0671.00
148_A179_V1.0661.00
40_K63_L1.0501.00
105_L121_D1.0481.00
104_L150_I1.0351.00
124_N146_A1.0151.00
34_A162_A1.0051.00
16_L24_I1.0031.00
74_V77_P1.0001.00
100_N119_V0.9941.00
131_L136_W0.9911.00
158_S161_E0.9861.00
30_L141_T0.9721.00
33_K165_E0.9581.00
169_G172_G0.9571.00
161_E165_E0.9461.00
83_F139_V0.9421.00
172_G176_A0.9281.00
97_L103_L0.9271.00
178_A182_G0.9100.99
16_L31_M0.9030.99
113_I117_E0.9020.99
77_P80_V0.9010.99
82_I88_I0.9010.99
97_L119_V0.8960.99
16_L61_V0.8910.99
127_K139_V0.8890.99
14_L31_M0.8810.99
18_G24_I0.8790.99
47_F58_V0.8710.99
77_P96_G0.8510.99
122_A146_A0.8490.99
159_L163_V0.8480.99
100_N118_Y0.8460.99
164_K173_E0.8410.99
34_A159_L0.8400.99
126_A130_G0.8370.99
34_A158_S0.8360.99
33_K166_E0.8350.99
149_R186_V0.8350.99
126_A139_V0.8330.99
128_E131_L0.8310.99
133_V174_L0.8260.99
64_S68_I0.8170.99
27_A83_F0.8090.99
147_L151_L0.7970.99
30_L162_A0.7970.99
22_Q53_R0.7880.99
103_L119_V0.7800.98
16_L81_A0.7750.98
135_G138_I0.7700.98
28_G59_S0.7630.98
21_G53_R0.7600.98
82_I105_L0.7550.98
82_I103_L0.7550.98
158_S162_A0.7530.98
84_D87_M0.7520.98
93_V96_G0.7520.98
102_F122_A0.7500.98
142_A181_I0.7460.98
56_P84_D0.7440.98
24_I83_F0.7430.98
92_N95_E0.7390.98
36_V42_A0.7390.98
95_E99_E0.7370.98
11_L64_S0.7330.98
135_G174_L0.7290.98
113_I116_N0.7150.97
145_G183_Y0.7120.97
67_P70_L0.7120.97
179_V183_Y0.7090.97
142_A182_G0.7080.97
74_V95_E0.7020.97
104_L126_A0.6950.97
60_F73_E0.6940.97
146_A150_I0.6930.97
168_P172_G0.6920.97
76_N98_K0.6900.97
20_G49_G0.6900.97
58_V93_V0.6890.97
138_I178_A0.6780.96
163_V172_G0.6760.96
171_I174_L0.6710.96
33_K36_V0.6710.96
46_P51_E0.6700.96
20_G57_V0.6690.96
80_V97_L0.6660.96
25_V50_G0.6660.96
167_F172_G0.6610.96
151_L154_P0.6580.96
159_L179_V0.6560.95
15_A77_P0.6440.95
124_N129_L0.6430.95
35_M61_V0.6410.95
12_I63_L0.6390.95
56_P87_M0.6350.95
80_V93_V0.6320.94
29_E44_S0.6310.94
44_S59_S0.6300.94
139_V143_M0.6280.94
56_P93_V0.6270.94
14_L79_G0.6270.94
130_G139_V0.6250.94
30_L166_E0.6240.94
76_N99_E0.6210.94
46_P59_S0.6210.94
50_G57_V0.6190.94
148_A156_L0.6140.94
37_L162_A0.6140.94
25_V46_P0.6120.93
148_A153_Q0.6120.93
106_N125_I0.6100.93
51_E54_G0.6090.93
82_I93_V0.6060.93
46_P52_R0.6050.93
163_V168_P0.6010.93
13_E78_D0.6010.93
13_E98_K0.5930.92
18_G55_A0.5920.92
83_F143_M0.5910.92
27_A144_I0.5900.92
94_T103_L0.5890.92
13_E76_N0.5860.92
31_M159_L0.5850.92
162_A166_E0.5850.92
133_V177_E0.5840.92
156_L159_L0.5810.92
17_R87_M0.5810.92
25_V57_V0.5800.92
108_N127_K0.5770.91
85_V107_T0.5750.91
29_E166_E0.5740.91
19_R87_M0.5730.91
29_E33_K0.5710.91
55_A87_M0.5710.91
129_L133_V0.5700.91
35_M40_K0.5690.91
72_R77_P0.5680.91
79_G102_F0.5650.90
47_F73_E0.5650.90
133_V182_G0.5600.90
102_F150_I0.5580.90
20_G25_V0.5580.90
26_T30_L0.5570.90
47_F50_G0.5500.89
44_S58_V0.5490.89
145_G178_A0.5460.89
52_R57_V0.5450.89
21_G31_M0.5430.89
85_V89_Q0.5430.89
41_Y66_K0.5420.89
28_G44_S0.5400.88
11_L62_R0.5390.88
106_N126_A0.5390.88
49_G52_R0.5380.88
44_S61_V0.5360.88
25_V44_S0.5330.88
16_L83_F0.5320.88
34_A38_E0.5300.88
52_R55_A0.5300.88
86_S101_G0.5270.87
130_G134_A0.5240.87
49_G57_V0.5240.87
13_E77_P0.5230.87
16_L28_G0.5230.87
154_P159_L0.5230.87
102_F128_E0.5220.87
104_L146_A0.5200.87
24_I29_E0.5170.86
150_I186_V0.5170.86
44_S48_F0.5140.86
38_E154_P0.5100.85
124_N142_A0.5080.85
43_Q62_R0.5080.85
154_P158_S0.5080.85
13_E74_V0.5040.85
30_L102_F0.5020.85
25_V29_E0.5000.84
48_F54_G0.5000.84
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3on3A 2 0.9158 100 0.169 Contact Map
3g2eA 4 0.9421 100 0.174 Contact Map
2raaA 1 0.9158 100 0.178 Contact Map
2c42A 2 1 100 0.204 Contact Map
5c4iB 1 0.9421 100 0.284 Contact Map
3fwzA 2 0.6895 63 0.92 Contact Map
1dxyA 5 0.8684 58.6 0.922 Contact Map
3wnvA 2 0.8684 58.4 0.922 Contact Map
1id1A 2 0.7368 57.9 0.922 Contact Map
3pp8A 2 0.8737 55.8 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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