Q97YS6 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97YS6 - Toluene-4-monooxygenase system protein E. (TmoE)

UniProt:	Q97YS6	Sequences: MTRLEDLEWYKRYKQMFGAFKSGPEGDPFFRDYEYRGYKKVWSTWPMLEKKLGRKKPSEYQVVTYALSYWADPRSPTYIYDKGPFELGTEHITQKWYKHFRDNSPFIKPLFERGEWHDYEDPYKLTYWTYNSMADDNETFLDKIYEEIVNTKYDWNLNEEVLELYKNVYDPLRYVFHIMQMESMYLATMAPTSSIANVFIFMGMDHLRRVQRISQRVKMLDIVYPSLGFGKETRKVFEESPIFQPTREVLEKMLVTYDVGEALVAFNLAVKFVLDELILQHLTQPFSKLGDEMIKHIHLSFYNDTLRHRHQAQELFKYAFSKEPSLKDVIKPWVKDWQEMGFKATEGFRDVLKGEYDNAIRQIRKAHSEYLGGIGL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	376 (306)
Sequences:	420 (254)
Seq/√Len:	14.5

SULSO - Q97YS6 Q97YT1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
235_K	239_E	4.982	1.00
252_K	340_M	4.565	1.00
152_K	201_F	3.663	0.99
176_F	206_H	3.597	0.99
119_Y	195_I	3.185	0.98
324_P	327_K	3.115	0.98
98_K	101_R	2.969	0.97
249_V	341_G	2.962	0.97
261_E	265_A	2.961	0.97
352_L	359_A	2.956	0.97
95_K	103_N	2.927	0.97
178_I	250_L	2.850	0.97
119_Y	315_L	2.728	0.96
320_F	330_I	2.727	0.96
241_P	245_P	2.722	0.96
195_I	259_V	2.708	0.96
245_P	297_I	2.581	0.94
268_L	316_F	2.578	0.94
248_E	343_K	2.544	0.94
261_E	337_W	2.365	0.91
161_V	286_F	2.325	0.90
109_P	184_M	2.288	0.89
84_P	194_S	2.283	0.89
130_Y	205_D	2.207	0.88
186_L	199_F	2.126	0.85
304_D	307_R	2.074	0.84
337_W	340_M	2.069	0.84
261_E	333_W	2.043	0.83
331_K	335_K	2.006	0.82
178_I	254_L	1.990	0.81
256_T	261_E	1.989	0.81
146_E	316_F	1.955	0.80
208_R	304_D	1.925	0.79
190_A	196_A	1.913	0.79
326_L	333_W	1.894	0.78
70_W	86_E	1.892	0.78
342_F	364_R	1.882	0.77
334_V	371_L	1.878	0.77
184_M	203_G	1.875	0.77
277_L	349_R	1.854	0.76
350_D	354_G	1.836	0.76
121_D	337_W	1.821	0.75
281_H	363_I	1.805	0.74
203_G	231_K	1.784	0.73
248_E	252_K	1.754	0.72
237_F	251_E	1.718	0.71
101_R	107_I	1.706	0.70
112_E	361_R	1.695	0.69
111_F	330_I	1.688	0.69
272_F	276_E	1.686	0.69
325_S	328_D	1.665	0.68
336_D	340_M	1.659	0.68
329_V	332_P	1.637	0.67
192_T	210_V	1.631	0.66
204_M	207_L	1.631	0.66
87_L	175_V	1.610	0.65
142_D	212_R	1.609	0.65
234_R	238_E	1.603	0.65
168_V	351_V	1.601	0.65
92_I	100_F	1.592	0.64
235_K	350_D	1.578	0.64
248_E	340_M	1.570	0.63
125_L	149_V	1.564	0.63
146_E	241_P	1.532	0.61
44_T	49_E	1.517	0.61
131_N	233_T	1.510	0.60
220_L	297_I	1.505	0.60
208_R	307_R	1.496	0.59
181_M	254_L	1.483	0.59
109_P	113_R	1.479	0.59
48_L	71_A	1.461	0.58
325_S	350_D	1.454	0.57
343_K	351_V	1.452	0.57
237_F	344_A	1.425	0.56
211_Q	277_L	1.388	0.54
361_R	374_I	1.386	0.53
119_Y	319_A	1.380	0.53
160_E	351_V	1.354	0.52
140_F	144_I	1.342	0.51
112_E	330_I	1.336	0.51
197_N	201_F	1.335	0.51
71_A	85_F	1.334	0.51
121_D	259_V	1.327	0.50
338_Q	368_S	1.313	0.49
160_E	343_K	1.313	0.49
112_E	323_E	1.280	0.48
127_Y	173_R	1.278	0.48
90_E	106_F	1.274	0.47
104_S	184_M	1.268	0.47
346_E	361_R	1.259	0.46
236_V	240_S	1.257	0.46
260_G	319_A	1.253	0.46
320_F	327_K	1.249	0.46
226_S	325_S	1.247	0.46
111_F	114_G	1.247	0.46
195_I	315_L	1.232	0.45
333_W	344_A	1.231	0.45
231_K	362_Q	1.230	0.45
274_L	305_T	1.229	0.45
165_Y	203_G	1.229	0.45
306_L	324_P	1.229	0.45
359_A	363_I	1.226	0.45
327_K	334_V	1.225	0.45
244_Q	251_E	1.221	0.44
264_V	269_A	1.219	0.44
116_W	333_W	1.218	0.44
141_L	347_G	1.216	0.44
241_P	327_K	1.214	0.44
134_A	208_R	1.213	0.44
330_I	336_D	1.169	0.42
181_M	252_K	1.161	0.41
167_N	240_S	1.151	0.41
120_E	189_M	1.142	0.40
338_Q	364_R	1.140	0.40
88_G	192_T	1.137	0.40
43_S	365_K	1.127	0.39
168_V	278_I	1.119	0.39
251_E	344_A	1.112	0.39
185_Y	189_M	1.111	0.38
278_I	367_H	1.106	0.38
316_F	363_I	1.101	0.38
146_E	327_K	1.095	0.38
265_A	269_A	1.090	0.37
134_A	307_R	1.087	0.37
233_T	269_A	1.086	0.37
134_A	304_D	1.085	0.37
156_N	374_I	1.084	0.37
148_I	177_H	1.084	0.37
252_K	317_K	1.084	0.37
85_F	227_L	1.082	0.37
256_T	282_L	1.074	0.37
336_D	343_K	1.073	0.37
331_K	343_K	1.071	0.36
214_S	225_P	1.067	0.36
334_V	356_Y	1.062	0.36
265_A	337_W	1.062	0.36
306_L	340_M	1.058	0.36
249_V	270_V	1.055	0.36
155_W	331_K	1.050	0.35
161_V	188_T	1.049	0.35
225_P	274_L	1.041	0.35
325_S	331_K	1.038	0.35
121_D	326_L	1.031	0.34
43_S	353_K	1.031	0.34
256_T	312_A	1.030	0.34
324_P	331_K	1.022	0.34
106_F	137_N	1.020	0.34
132_S	299_L	1.004	0.33
118_D	335_K	1.003	0.33
118_D	264_V	0.990	0.32
226_S	278_I	0.988	0.32
190_A	200_I	0.986	0.32
96_W	106_F	0.974	0.32
261_E	336_D	0.973	0.32
141_L	209_R	0.971	0.31
131_N	148_I	0.970	0.31
117_H	194_S	0.967	0.31
102_D	149_V	0.963	0.31
268_L	371_L	0.961	0.31
309_R	360_I	0.956	0.31
112_E	325_S	0.955	0.31
123_Y	134_A	0.952	0.31
154_D	234_R	0.951	0.31
249_V	347_G	0.950	0.30
268_L	351_V	0.944	0.30
120_E	194_S	0.943	0.30
109_P	114_G	0.942	0.30
128_W	197_N	0.941	0.30
88_G	210_V	0.938	0.30
119_Y	157_L	0.937	0.30
244_Q	267_N	0.937	0.30
249_V	269_A	0.934	0.30
155_W	332_P	0.930	0.30
168_V	356_Y	0.916	0.29
152_K	155_W	0.913	0.29
264_V	352_L	0.902	0.28
110_L	372_G	0.901	0.28
125_L	133_M	0.893	0.28
176_F	294_I	0.888	0.28
174_Y	210_V	0.884	0.27
89_T	279_L	0.880	0.27
154_D	216_R	0.876	0.27
253_M	368_S	0.874	0.27
184_M	363_I	0.870	0.27
370_Y	373_G	0.869	0.27
181_M	186_L	0.866	0.27
127_Y	171_P	0.866	0.27
308_H	312_A	0.864	0.27
305_T	312_A	0.858	0.26
112_E	260_G	0.856	0.26
172_L	271_K	0.855	0.26
47_M	145_Y	0.855	0.26
264_V	330_I	0.854	0.26
169_Y	210_V	0.847	0.26
82_K	178_I	0.842	0.26
207_L	264_V	0.839	0.26
327_K	331_K	0.837	0.25
111_F	119_Y	0.832	0.25
237_F	243_F	0.829	0.25
186_L	262_A	0.828	0.25
367_H	371_L	0.828	0.25
356_Y	360_I	0.827	0.25
206_H	286_F	0.826	0.25
83_G	89_T	0.826	0.25
358_N	369_E	0.824	0.25
105_P	230_G	0.824	0.25
365_K	368_S	0.821	0.25
48_L	86_E	0.818	0.25
47_M	50_K	0.815	0.25
355_E	359_A	0.811	0.24
201_F	211_Q	0.811	0.24
155_W	201_F	0.809	0.24
322_K	326_L	0.806	0.24
111_F	351_V	0.806	0.24
172_L	246_T	0.805	0.24
278_I	335_K	0.803	0.24
335_K	342_F	0.803	0.24
201_F	205_D	0.800	0.24
231_K	327_K	0.798	0.24
126_T	215_Q	0.793	0.24
49_E	199_F	0.793	0.24
160_E	306_L	0.792	0.24
110_L	226_S	0.790	0.24
176_F	216_R	0.786	0.23
265_A	315_L	0.778	0.23
278_I	309_R	0.774	0.23
172_L	275_D	0.774	0.23
242_I	316_F	0.770	0.23
133_M	307_R	0.769	0.23
355_E	368_S	0.766	0.23
109_P	243_F	0.766	0.23
113_R	322_K	0.765	0.23
324_P	343_K	0.765	0.23
104_S	177_H	0.765	0.23
249_V	321_S	0.762	0.22
121_D	205_D	0.761	0.22
267_N	330_I	0.758	0.22
282_L	363_I	0.754	0.22
232_E	245_P	0.754	0.22
222_I	225_P	0.753	0.22
247_R	344_A	0.752	0.22
281_H	368_S	0.751	0.22
112_E	364_R	0.750	0.22
317_K	321_S	0.749	0.22
150_N	176_F	0.749	0.22
357_D	365_K	0.748	0.22
219_M	341_G	0.748	0.22
127_Y	201_F	0.748	0.22
108_K	243_F	0.745	0.22
198_V	282_L	0.745	0.22
186_L	362_Q	0.740	0.22
186_L	324_P	0.740	0.22
275_D	304_D	0.739	0.22
237_F	247_R	0.739	0.22
155_W	342_F	0.736	0.21
91_H	114_G	0.735	0.21
268_L	312_A	0.733	0.21
165_Y	303_N	0.731	0.21
185_Y	305_T	0.729	0.21
47_M	279_L	0.728	0.21
110_L	152_K	0.728	0.21
361_R	372_G	0.728	0.21
232_E	342_F	0.727	0.21
94_Q	134_A	0.724	0.21
161_V	371_L	0.722	0.21
87_L	178_I	0.720	0.21
283_T	294_I	0.719	0.21
137_N	307_R	0.719	0.21
170_D	213_I	0.718	0.21
91_H	248_E	0.717	0.21
127_Y	131_N	0.715	0.21
305_T	309_R	0.714	0.21
43_S	324_P	0.711	0.21
104_S	293_M	0.709	0.20
95_K	100_F	0.709	0.20
222_I	226_S	0.709	0.20
141_L	293_M	0.708	0.20
49_E	143_K	0.706	0.20
71_A	86_E	0.706	0.20
280_Q	374_I	0.702	0.20
50_K	101_R	0.701	0.20
287_S	351_V	0.701	0.20
107_I	315_L	0.699	0.20
206_H	216_R	0.699	0.20
268_L	303_N	0.698	0.20
99_H	102_D	0.696	0.20
121_D	251_E	0.696	0.20
287_S	295_K	0.695	0.20
203_G	317_K	0.695	0.20
186_L	307_R	0.692	0.20
161_V	278_I	0.691	0.20
168_V	240_S	0.690	0.20
46_P	295_K	0.690	0.20
203_G	296_H	0.689	0.20
101_R	188_T	0.689	0.20
246_T	249_V	0.689	0.20
112_E	290_G	0.688	0.20
130_Y	201_F	0.688	0.20
158_N	190_A	0.686	0.20
171_P	180_Q	0.684	0.20
286_F	291_D	0.680	0.19
107_I	185_Y	0.679	0.19
352_L	356_Y	0.679	0.19
127_Y	180_Q	0.679	0.19
43_S	48_L	0.678	0.19
43_S	354_G	0.677	0.19
86_E	141_L	0.675	0.19
338_Q	354_G	0.674	0.19
290_G	294_I	0.673	0.19
346_E	349_R	0.669	0.19
42_W	72_D	0.669	0.19
278_I	353_K	0.668	0.19
156_N	201_F	0.668	0.19
244_Q	258_D	0.666	0.19
266_F	370_Y	0.663	0.19
211_Q	253_M	0.662	0.19
338_Q	367_H	0.661	0.19
46_P	49_E	0.660	0.19
176_F	198_V	0.657	0.19
160_E	285_P	0.657	0.19
206_H	271_K	0.657	0.19
212_R	301_F	0.657	0.19
232_E	278_I	0.656	0.19
231_K	235_K	0.655	0.19
316_F	330_I	0.655	0.19
324_P	340_M	0.655	0.19
359_A	375_G	0.654	0.19
259_V	337_W	0.652	0.19
332_P	362_Q	0.651	0.18
226_S	369_E	0.650	0.18
96_W	221_D	0.645	0.18
145_Y	301_F	0.645	0.18
331_K	336_D	0.643	0.18
251_E	263_L	0.643	0.18
128_W	204_M	0.641	0.18
130_Y	303_N	0.641	0.18
193_S	203_G	0.638	0.18
93_T	233_T	0.638	0.18
175_V	208_R	0.637	0.18
98_K	178_I	0.636	0.18
206_H	294_I	0.634	0.18
111_F	319_A	0.634	0.18
167_N	368_S	0.630	0.18
199_F	203_G	0.629	0.18
190_A	194_S	0.628	0.18
335_K	339_E	0.627	0.18
235_K	332_P	0.626	0.18
178_I	247_R	0.626	0.18
232_E	358_N	0.624	0.18
248_E	339_E	0.623	0.18
220_L	269_A	0.622	0.18
268_L	294_I	0.622	0.18
343_K	355_E	0.621	0.17
160_E	361_R	0.619	0.17
119_Y	198_V	0.619	0.17
239_E	357_D	0.618	0.17
334_V	346_E	0.617	0.17
115_E	260_G	0.615	0.17
351_V	365_K	0.612	0.17
321_S	362_Q	0.610	0.17
235_K	327_K	0.609	0.17
241_P	363_I	0.607	0.17
232_E	303_N	0.607	0.17
327_K	343_K	0.605	0.17
173_R	244_Q	0.605	0.17
162_L	314_E	0.604	0.17
164_L	324_P	0.603	0.17
299_L	310_H	0.599	0.17
83_G	160_E	0.598	0.17
123_Y	326_L	0.597	0.17
83_G	155_W	0.594	0.17
80_Y	134_A	0.591	0.17
215_Q	266_F	0.591	0.17
154_D	201_F	0.589	0.16
157_L	282_L	0.589	0.16
239_E	365_K	0.588	0.16
291_D	294_I	0.587	0.16
243_F	333_W	0.585	0.16
245_P	359_A	0.585	0.16
276_E	353_K	0.584	0.16
87_L	100_F	0.581	0.16
236_V	339_E	0.580	0.16
170_D	292_E	0.578	0.16
139_T	343_K	0.578	0.16
286_F	334_V	0.573	0.16
341_G	366_A	0.573	0.16
162_L	261_E	0.573	0.16
132_S	201_F	0.571	0.16
269_A	335_K	0.570	0.16
320_F	332_P	0.570	0.16
256_T	262_A	0.570	0.16
328_D	371_L	0.568	0.16
154_D	337_W	0.566	0.16
235_K	336_D	0.565	0.16
208_R	214_S	0.564	0.16
135_D	203_G	0.564	0.16
335_K	357_D	0.563	0.16
179_M	306_L	0.562	0.16
145_Y	165_Y	0.562	0.16
139_T	277_L	0.562	0.16
281_H	362_Q	0.561	0.16
353_K	361_R	0.561	0.16
282_L	337_W	0.560	0.16
174_Y	326_L	0.558	0.16
109_P	115_E	0.557	0.16
109_P	195_I	0.557	0.16
364_R	368_S	0.555	0.15
126_T	211_Q	0.553	0.15
250_L	281_H	0.553	0.15
253_M	352_L	0.549	0.15
177_H	185_Y	0.548	0.15
143_K	332_P	0.546	0.15
226_S	316_F	0.546	0.15
157_L	269_A	0.545	0.15
339_E	368_S	0.542	0.15
270_V	341_G	0.542	0.15
328_D	368_S	0.540	0.15
152_K	253_M	0.540	0.15
110_L	332_P	0.540	0.15
185_Y	188_T	0.538	0.15
98_K	270_V	0.538	0.15
296_H	303_N	0.538	0.15
243_F	267_N	0.538	0.15
130_Y	225_P	0.537	0.15
210_V	326_L	0.537	0.15
171_P	217_V	0.536	0.15
152_K	156_N	0.536	0.15
178_I	184_M	0.535	0.15
267_N	356_Y	0.534	0.15
329_V	351_V	0.533	0.15
339_E	364_R	0.532	0.15
100_F	232_E	0.528	0.15
190_A	198_V	0.528	0.15
96_W	332_P	0.526	0.15
236_V	348_F	0.525	0.15
195_I	291_D	0.523	0.15
240_S	368_S	0.522	0.15
126_T	212_R	0.520	0.15
167_N	232_E	0.519	0.14
316_F	365_K	0.518	0.14
107_I	162_L	0.516	0.14
169_Y	321_S	0.516	0.14
338_Q	361_R	0.516	0.14
118_D	175_V	0.514	0.14
273_V	367_H	0.510	0.14
104_S	297_I	0.510	0.14
144_I	282_L	0.509	0.14
240_S	372_G	0.508	0.14
169_Y	351_V	0.507	0.14
121_D	311_Q	0.507	0.14
114_G	322_K	0.507	0.14
174_Y	237_F	0.507	0.14
82_K	123_Y	0.507	0.14
91_H	291_D	0.505	0.14
93_T	104_S	0.502	0.14
119_Y	259_V	0.502	0.14
145_Y	199_F	0.501	0.14
99_H	207_L	0.500	0.14
214_S	230_G	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1mhyB	2	0.9255	100	0.328	Contact Map
1mtyB	2	0.9309	100	0.331	Contact Map
3u52C	2	0.859	100	0.333	Contact Map
2incB	2	0.8564	100	0.335	Contact Map
3ge3B	2	0.8085	100	0.349	Contact Map
3u52A	2	0.7846	100	0.436	Contact Map
3ge3A	2	0.7793	100	0.438	Contact Map
2incA	2	0.7846	100	0.441	Contact Map
1mtyD	2	0.7926	100	0.469	Contact Map
4mudA	2	0.5532	99.5	0.879	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.