GREMLIN Database
Q97YQ6 - Glutamine-fructose-6-phosphate transaminase (Isomerizing) (GlmS-2)
UniProt: Q97YQ6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 584 (580)
Sequences: 3769 (2062)
Seq/√Len: 85.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
110_D147_R4.9241.00
114_K133_N4.3501.00
281_K328_G4.0361.00
359_G372_S4.0191.00
218_N222_N3.9201.00
258_L432_L3.8301.00
23_K56_E3.5381.00
285_I295_G3.4941.00
141_S165_F3.4001.00
127_I148_V3.2711.00
205_T226_P3.2651.00
388_A391_T3.2601.00
348_K371_E3.2271.00
136_N139_N3.2211.00
18_I66_A3.1241.00
131_L144_V3.0831.00
256_Q260_N3.0801.00
51_N574_T3.0431.00
440_E563_K2.9161.00
197_N230_R2.7141.00
258_L397_V2.6961.00
166_A184_V2.6651.00
92_K160_D2.6371.00
89_C116_H2.6191.00
116_H132_E2.5781.00
48_I58_S2.5711.00
138_L217_Y2.5201.00
116_H133_N2.4891.00
127_I154_L2.4891.00
163_K208_V2.4811.00
334_I399_L2.4421.00
166_A207_A2.4311.00
215_Q223_E2.3891.00
137_Y165_F2.3851.00
116_H129_H2.3761.00
433_M438_E2.3731.00
175_I207_A2.3591.00
432_L555_I2.3481.00
95_V128_P2.3331.00
281_K326_T2.2241.00
48_I80_L2.2191.00
175_I214_V2.2121.00
471_A482_A2.2011.00
81_E121_T2.1671.00
89_C132_E2.1511.00
131_L156_F2.1431.00
178_T181_C2.1131.00
177_I199_I2.1041.00
428_L551_I2.1041.00
404_L421_L2.0871.00
53_S57_I2.0591.00
295_G334_I2.0571.00
252_Y440_E2.0521.00
302_F309_V2.0511.00
302_F406_T2.0471.00
20_K193_G2.0121.00
137_Y158_T1.9951.00
261_S378_I1.9941.00
155_V164_I1.9801.00
408_L418_I1.9751.00
566_V572_I1.9741.00
149_K514_D1.9661.00
302_F403_S1.9591.00
417_E420_S1.9421.00
182_K214_V1.9131.00
270_L273_A1.9071.00
108_R112_I1.9011.00
506_L520_I1.8791.00
95_V124_A1.8651.00
313_S486_Q1.8631.00
333_A347_I1.8631.00
487_L516_Y1.8561.00
468_L484_G1.8431.00
155_V184_V1.8421.00
47_K80_L1.8381.00
202_P226_P1.8371.00
138_L208_V1.8341.00
392_F466_I1.8331.00
177_I214_V1.8271.00
37_Y63_A1.8221.00
434_V438_E1.8201.00
282_N310_N1.8151.00
197_N228_I1.8091.00
349_M352_Q1.8061.00
145_M148_V1.8011.00
141_S156_F1.7941.00
312_V320_Y1.7871.00
92_K159_I1.7851.00
162_D211_W1.7781.00
290_T388_A1.7621.00
435_R552_S1.7521.00
131_L141_S1.7361.00
11_D181_C1.7331.00
542_I553_N1.7231.00
304_E322_L1.7221.00
470_G557_L1.7201.00
505_I560_L1.7191.00
325_V355_A1.7161.00
49_L79_T1.7151.00
18_I68_G1.7131.00
54_K57_I1.7041.00
424_E431_Q1.6831.00
87_T94_A1.6801.00
357_I372_S1.6661.00
58_S80_L1.6611.00
51_N571_P1.6541.00
8_V211_W1.6521.00
257_A394_S1.6431.00
414_D417_E1.6351.00
43_L94_A1.6281.00
280_A330_V1.6271.00
292_L296_F1.6261.00
326_T329_S1.6211.00
448_P567_R1.6191.00
196_E230_R1.6181.00
177_I182_K1.6181.00
139_N142_L1.6131.00
434_V536_D1.6031.00
8_V65_V1.5991.00
208_V215_Q1.5951.00
424_E546_R1.5801.00
243_F252_Y1.5771.00
36_A94_A1.5761.00
93_I158_T1.5711.00
534_A541_S1.5661.00
144_V148_V1.5601.00
537_G544_A1.5601.00
361_T369_A1.5551.00
182_K213_D1.5501.00
378_I394_S1.5391.00
216_V226_P1.5391.00
317_F325_V1.5381.00
19_N35_I1.5111.00
93_I137_Y1.5101.00
15_V35_I1.5101.00
331_I355_A1.5101.00
563_K567_R1.5091.00
441_K444_E1.5031.00
95_V127_I1.5000.99
335_S368_L1.4960.99
270_L274_S1.4930.99
245_H562_Y1.4840.99
109_E113_A1.4840.99
166_A175_I1.4830.99
427_E431_Q1.4810.99
106_K149_K1.4730.99
163_K210_S1.4700.99
405_Y409_H1.4660.99
210_S213_D1.4610.99
283_V332_I1.4490.99
199_I214_V1.4480.99
169_S204_N1.4450.99
104_Y108_R1.4430.99
364_V377_P1.4340.99
458_S523_I1.4300.99
46_K58_S1.4280.99
188_L200_I1.4100.99
140_S144_V1.4000.99
464_Y468_L1.3850.99
39_E42_S1.3850.99
49_L78_P1.3850.99
458_S506_L1.3820.99
520_I530_I1.3720.99
53_S56_E1.3610.99
145_M167_I1.3560.99
20_K23_K1.3530.99
87_T91_G1.3490.99
36_A43_L1.3480.99
431_Q545_T1.3460.99
301_Y400_K1.3250.99
299_S310_N1.3210.99
351_K373_N1.3170.99
369_A375_Y1.3170.99
466_I554_V1.3080.99
420_S546_R1.3080.99
199_I216_V1.3070.99
244_P566_V1.3060.99
284_Y317_F1.3060.99
142_L217_Y1.3050.99
138_L142_L1.2920.98
404_L418_I1.2840.98
344_I348_K1.2780.98
108_R118_F1.2770.98
201_M207_A1.2660.98
259_I433_M1.2570.98
341_S345_R1.2390.98
513_E538_D1.2370.98
158_T161_I1.2310.98
360_I399_L1.2290.98
110_D133_N1.2270.98
446_L531_V1.2220.98
109_E112_I1.2220.98
156_F165_F1.2210.98
533_V542_I1.2150.98
359_G368_L1.2120.98
439_M442_E1.2050.98
38_L157_V1.2040.98
565_G570_L1.2020.98
331_I350_A1.2020.98
450_L560_L1.1970.97
137_Y141_S1.1940.97
118_F126_V1.1910.97
430_K433_M1.1880.97
347_I368_L1.1870.97
276_I356_V1.1860.97
560_L564_L1.1790.97
92_K132_E1.1790.97
261_S398_V1.1760.97
498_T528_D1.1750.97
283_V330_V1.1690.97
138_L206_V1.1670.97
376_L398_V1.1550.97
9_C13_I1.1550.97
15_V63_A1.1500.97
208_V217_Y1.1470.97
217_Y223_E1.1460.97
305_I403_S1.1430.97
233_Y238_A1.1400.97
407_G413_N1.1360.97
240_K574_T1.1350.97
248_L252_Y1.1340.96
178_T182_K1.1320.96
7_F13_I1.1290.96
431_Q552_S1.1280.96
545_T552_S1.1280.96
89_C129_H1.1250.96
332_I402_L1.1240.96
105_E109_E1.1240.96
36_A45_I1.1200.96
42_S159_I1.1190.96
155_V166_A1.1180.96
298_S399_L1.1140.96
449_K529_V1.1110.96
458_S490_L1.1060.96
152_Y169_S1.1040.96
453_E568_K1.1020.96
509_P553_N1.0990.96
413_N418_I1.0990.96
511_E547_D1.0950.96
282_N326_T1.0920.96
131_L140_S1.0910.96
176_G195_A1.0910.96
455_L505_I1.0910.96
435_R439_M1.0880.96
177_I228_I1.0870.96
293_H296_F1.0870.96
92_K158_T1.0850.95
254_I393_T1.0840.95
49_L77_W1.0820.95
417_E421_L1.0800.95
108_R126_V1.0790.95
440_E444_E1.0790.95
534_A538_D1.0770.95
10_K211_W1.0730.95
165_F208_V1.0670.95
282_N308_N1.0670.95
333_A357_I1.0660.95
378_I395_T1.0660.95
329_S355_A1.0640.95
65_V164_I1.0620.95
143_N146_K1.0600.95
6_A184_V1.0580.95
318_P345_R1.0540.95
49_L54_K1.0480.95
504_V528_D1.0480.95
38_L65_V1.0410.94
356_V373_N1.0380.94
444_E448_P1.0330.94
447_A560_L1.0330.94
439_M443_A1.0320.94
356_V374_V1.0320.94
508_K513_E1.0310.94
428_L552_S1.0300.94
333_A372_S1.0280.94
298_S302_F1.0260.94
303_S320_Y1.0230.94
432_L551_I1.0210.94
19_N56_E1.0200.94
283_V307_L1.0200.94
139_N143_N1.0180.94
521_R524_K1.0140.94
11_D183_Y1.0130.93
283_V309_V1.0130.93
200_I229_K1.0110.93
571_P574_T1.0080.93
155_V209_I1.0020.93
538_D541_S1.0010.93
559_L563_K1.0000.93
248_L440_E0.9920.93
245_H248_L0.9900.93
244_P248_L0.9880.93
535_E544_A0.9850.93
134_S139_N0.9840.92
23_K52_I0.9840.92
90_N132_E0.9810.92
266_M426_E0.9800.92
271_S274_S0.9790.92
189_P192_S0.9760.92
417_E546_R0.9750.92
490_L495_I0.9700.92
349_M353_R0.9670.92
442_E445_K0.9660.92
265_L401_V0.9650.92
77_W527_G0.9640.92
302_F402_L0.9610.92
463_N507_I0.9580.91
445_K448_P0.9550.91
47_K87_T0.9540.91
333_A350_A0.9530.91
456_Y502_Y0.9510.91
523_I530_I0.9500.91
8_V162_D0.9490.91
407_G418_I0.9490.91
392_F465_P0.9480.91
184_V209_I0.9470.91
51_N240_K0.9460.91
523_I528_D0.9440.91
397_V551_I0.9430.91
284_Y329_S0.9420.91
49_L80_L0.9400.91
65_V162_D0.9390.91
306_S403_S0.9380.91
229_K365_G0.9380.91
405_Y408_L0.9360.90
182_K212_N0.9360.90
137_Y156_F0.9360.90
454_S502_Y0.9350.90
94_A157_V0.9330.90
39_E44_V0.9310.90
168_N348_K0.9290.90
287_G291_S0.9260.90
15_V37_Y0.9260.90
111_L118_F0.9240.90
57_I61_D0.9210.90
77_W121_T0.9200.90
424_E427_E0.9190.90
110_D114_K0.9190.90
380_A394_S0.9180.90
307_L410_S0.9170.90
112_I117_K0.9150.89
285_I309_V0.9130.89
369_A377_P0.9130.89
142_L206_V0.9110.89
12_S64_R0.9110.89
285_I311_V0.9080.89
207_A214_V0.9080.89
344_I367_R0.9050.89
401_V422_K0.9050.89
385_A391_T0.9040.89
157_V164_I0.9030.89
168_N203_E0.9030.89
465_P494_P0.9020.89
297_I466_I0.9000.89
507_I557_L0.8980.89
121_T521_R0.8970.89
293_H468_L0.8960.88
152_Y219_I0.8950.88
127_I144_V0.8940.88
48_I54_K0.8930.88
151_I170_G0.8890.88
129_H132_E0.8890.88
454_S481_H0.8890.88
272_L275_M0.8870.88
323_K349_M0.8830.88
444_E563_K0.8800.88
199_I228_I0.8770.87
306_S410_S0.8750.87
262_F425_I0.8730.87
181_C195_A0.8720.87
81_E119_V0.8710.87
179_Q197_N0.8710.87
134_S140_S0.8680.87
245_H566_V0.8670.87
216_V224_V0.8660.87
24_K193_G0.8610.86
457_I474_F0.8610.86
127_I145_M0.8610.86
161_I165_F0.8590.86
415_R419_S0.8590.86
474_F480_T0.8570.86
457_I557_L0.8560.86
102_D515_L0.8550.86
231_V365_G0.8530.86
453_E499_N0.8510.86
252_Y436_L0.8500.86
379_T382_P0.8500.86
465_P484_G0.8480.86
282_N329_S0.8470.86
519_V522_S0.8460.85
195_A230_R0.8450.85
280_A356_V0.8440.85
45_I87_T0.8400.85
427_E430_K0.8390.85
93_I128_P0.8360.85
247_M385_A0.8360.85
385_A494_P0.8360.85
56_E60_S0.8350.85
19_N59_V0.8340.85
290_T294_A0.8320.84
385_A392_F0.8320.84
138_L215_Q0.8320.84
281_K329_S0.8320.84
279_G328_G0.8300.84
11_D17_I0.8260.84
272_L376_L0.8260.84
135_T139_N0.8240.84
420_S424_E0.8240.84
498_T504_V0.8240.84
52_I68_G0.8230.84
314_A523_I0.8230.84
393_T555_I0.8220.84
534_A539_M0.8210.84
276_I279_G0.8200.84
552_S556_P0.8190.84
17_I194_F0.8190.84
277_V406_T0.8180.83
188_L192_S0.8170.83
285_I399_L0.8160.83
296_F311_V0.8150.83
175_I201_M0.8150.83
256_Q433_M0.8150.83
37_Y66_A0.8120.83
185_S190_S0.8110.83
347_I372_S0.8100.83
119_V129_H0.8090.83
52_I59_V0.8080.83
280_A329_S0.8060.83
450_L455_L0.8030.82
184_V207_A0.8030.82
392_F554_V0.7990.82
359_G375_Y0.7950.82
298_S403_S0.7950.82
129_H133_N0.7950.82
455_L474_F0.7940.82
239_E246_F0.7940.82
182_K209_I0.7910.81
536_D544_A0.7910.81
463_N549_T0.7890.81
364_V375_Y0.7890.81
299_S303_S0.7860.81
360_I402_L0.7840.81
471_A484_G0.7830.81
89_C133_N0.7830.81
364_V369_A0.7820.81
248_L563_K0.7810.81
458_S467_A0.7800.80
322_L353_R0.7790.80
7_F17_I0.7780.80
431_Q435_R0.7740.80
196_E234_K0.7730.80
424_E548_L0.7730.80
158_T165_F0.7730.80
292_L313_S0.7700.80
248_L562_Y0.7700.80
175_I199_I0.7690.80
446_L450_L0.7680.79
258_L378_I0.7680.79
551_I556_P0.7670.79
278_Y409_H0.7660.79
512_A547_D0.7650.79
243_F248_L0.7640.79
136_N163_K0.7630.79
470_G477_A0.7620.79
423_S427_E0.7610.79
290_T496_V0.7610.79
12_S62_K0.7580.79
474_F478_S0.7560.78
534_A537_G0.7560.78
470_G554_V0.7560.78
564_L568_K0.7520.78
47_K81_E0.7510.78
118_F130_L0.7430.77
286_I317_F0.7430.77
499_N528_D0.7430.77
261_S394_S0.7420.77
45_I94_A0.7410.77
286_I331_I0.7390.77
166_A201_M0.7390.77
467_A507_I0.7390.77
506_L516_Y0.7370.77
443_A559_L0.7370.77
421_L548_L0.7360.76
325_V329_S0.7350.76
191_L198_A0.7340.76
162_D210_S0.7330.76
164_I184_V0.7330.76
65_V157_V0.7320.76
111_L115_G0.7320.76
500_K527_G0.7320.76
296_F468_L0.7310.76
202_P205_T0.7300.76
388_A496_V0.7290.76
565_G572_I0.7290.76
13_I16_S0.7270.76
301_Y403_S0.7260.75
154_L167_I0.7260.75
350_A355_A0.7260.75
163_K166_A0.7250.75
330_V358_L0.7240.75
43_L87_T0.7190.75
301_Y396_I0.7190.75
110_D113_A0.7180.75
391_T581_A0.7180.75
443_A560_L0.7160.74
205_T218_N0.7160.74
257_A261_S0.7150.74
111_L130_L0.7150.74
206_V217_Y0.7130.74
142_L221_G0.7130.74
77_W81_E0.7130.74
285_I332_I0.7120.74
201_M205_T0.7100.74
450_L564_L0.7100.74
248_L559_L0.7090.74
91_G132_E0.7080.74
456_Y499_N0.7070.74
402_L406_T0.7060.73
421_L424_E0.7050.73
294_A399_L0.7050.73
333_A343_V0.7040.73
175_I216_V0.7000.73
455_L564_L0.6990.73
270_L275_M0.6970.73
485_I494_P0.6970.73
298_S301_Y0.6970.73
408_L415_R0.6950.72
360_I378_I0.6950.72
93_I160_D0.6940.72
257_A380_A0.6930.72
422_K426_E0.6930.72
149_K169_S0.6920.72
456_Y572_I0.6920.72
7_F181_C0.6910.72
192_S233_Y0.6890.72
8_V209_I0.6880.72
192_S195_A0.6870.71
452_K529_V0.6870.71
490_L523_I0.6860.71
333_A359_G0.6840.71
93_I140_S0.6820.71
318_P515_L0.6820.71
6_A155_V0.6820.71
89_C117_K0.6810.71
12_S15_V0.6810.71
96_V174_M0.6810.71
22_L33_A0.6800.71
396_I551_I0.6790.71
12_S16_S0.6780.70
299_S311_V0.6750.70
138_L165_F0.6740.70
457_I561_A0.6740.70
233_Y365_G0.6740.70
221_G224_V0.6730.70
46_K59_V0.6710.70
87_T129_H0.6710.70
423_S426_E0.6700.70
465_P468_L0.6700.70
64_R211_W0.6690.69
302_F306_S0.6690.69
134_S143_N0.6660.69
48_I52_I0.6650.69
508_K520_I0.6640.69
396_I400_K0.6640.69
413_N417_E0.6630.69
513_E541_S0.6620.69
193_G196_E0.6620.69
348_K367_R0.6600.68
218_N221_G0.6600.68
351_K371_E0.6600.68
368_L377_P0.6600.68
393_T551_I0.6590.68
143_N147_R0.6570.68
1_M4_I0.6560.68
397_V425_I0.6550.68
393_T554_V0.6550.68
444_E567_R0.6540.68
418_I422_K0.6530.68
100_I518_K0.6530.68
262_F397_V0.6530.68
454_S485_I0.6520.67
231_V238_A0.6500.67
91_G119_V0.6500.67
171_Q341_S0.6490.67
107_I148_V0.6490.67
313_S488_G0.6480.67
478_S570_L0.6470.67
260_N378_I0.6450.67
376_L402_L0.6440.66
127_I156_F0.6440.66
18_I35_I0.6420.66
174_M344_I0.6410.66
435_R443_A0.6410.66
403_S407_G0.6410.66
404_L407_G0.6390.66
203_E348_K0.6370.66
47_K119_V0.6370.66
427_E545_T0.6360.66
105_E108_R0.6360.66
400_K421_L0.6350.65
510_V535_E0.6340.65
175_I184_V0.6320.65
291_S334_I0.6320.65
258_L435_R0.6320.65
392_F494_P0.6310.65
218_N224_V0.6300.65
397_V428_L0.6300.65
183_Y194_F0.6290.65
532_T541_S0.6280.65
268_K273_A0.6270.64
447_A567_R0.6260.64
463_N553_N0.6260.64
174_M191_L0.6250.64
392_F463_N0.6250.64
192_S196_E0.6250.64
200_I385_A0.6250.64
455_L482_A0.6240.64
264_S379_T0.6230.64
431_Q434_V0.6230.64
332_I358_L0.6200.64
313_S490_L0.6190.63
247_M477_A0.6180.63
57_I60_S0.6170.63
418_I421_L0.6170.63
136_N161_I0.6170.63
407_G411_G0.6150.63
174_M188_L0.6150.63
367_R371_E0.6140.63
465_P471_A0.6140.63
535_E549_T0.6140.63
180_E183_Y0.6130.63
130_L148_V0.6130.63
173_L184_V0.6120.63
97_M171_Q0.6120.63
443_A556_P0.6110.62
365_G369_A0.6090.62
291_S490_L0.6090.62
293_H361_T0.6080.62
304_E417_E0.6060.62
424_E428_L0.6060.62
501_G527_G0.6060.62
323_K388_A0.6040.62
495_I498_T0.6040.62
510_V513_E0.6030.61
170_G511_E0.6030.61
63_A66_A0.6000.61
450_L505_I0.6000.61
67_I155_V0.6000.61
457_I487_L0.5990.61
195_A228_I0.5990.61
510_V538_D0.5980.61
495_I528_D0.5970.61
183_Y191_L0.5960.61
148_V152_Y0.5960.61
286_I333_A0.5940.60
35_I59_V0.5940.60
533_V553_N0.5940.60
233_Y364_V0.5930.60
303_S311_V0.5930.60
315_A488_G0.5930.60
388_A528_D0.5920.60
451_D568_K0.5920.60
495_I499_N0.5920.60
455_L502_Y0.5920.60
545_T548_L0.5900.60
297_I550_P0.5900.60
333_A368_L0.5890.60
456_Y498_T0.5890.60
452_K503_P0.5890.60
428_L548_L0.5880.59
102_D345_R0.5870.59
170_G203_E0.5860.59
384_M574_T0.5850.59
508_K516_Y0.5830.59
79_T83_A0.5820.59
171_Q523_I0.5820.59
275_M552_S0.5820.59
90_N116_H0.5810.59
141_S144_V0.5800.58
95_V154_L0.5800.58
24_K239_E0.5790.58
456_Y528_D0.5790.58
234_K237_I0.5790.58
395_T399_L0.5770.58
266_M422_K0.5770.58
463_N509_P0.5760.58
22_L68_G0.5760.58
35_I68_G0.5760.58
494_P507_I0.5750.58
291_S311_V0.5740.58
244_P574_T0.5740.58
96_V277_V0.5710.57
16_S56_E0.5710.57
205_T224_V0.5710.57
533_V557_L0.5700.57
104_Y521_R0.5700.57
297_I300_Y0.5690.57
322_L512_A0.5680.57
511_E544_A0.5670.57
108_R128_P0.5670.57
15_V19_N0.5670.57
515_L518_K0.5660.57
18_I37_Y0.5660.57
277_V280_A0.5660.57
68_G335_S0.5630.56
368_L372_S0.5630.56
118_F129_H0.5630.56
167_I204_N0.5620.56
579_V583_I0.5610.56
16_S20_K0.5610.56
298_S421_L0.5590.56
296_F461_G0.5580.56
27_Y187_D0.5570.55
6_A354_G0.5570.55
507_I553_N0.5550.55
210_S214_V0.5550.55
474_F564_L0.5550.55
293_H395_T0.5550.55
465_P482_A0.5550.55
471_A496_V0.5540.55
432_L436_L0.5540.55
142_L146_K0.5530.55
407_G412_K0.5520.55
284_Y310_N0.5520.55
69_H84_H0.5520.55
319_Y345_R0.5520.55
161_I208_V0.5510.55
291_S391_T0.5510.55
287_G311_V0.5500.55
257_A265_L0.5500.55
13_I17_I0.5500.55
210_S215_Q0.5490.54
351_K357_I0.5480.54
80_L83_A0.5480.54
10_K180_E0.5470.54
388_A498_T0.5470.54
283_V302_F0.5460.54
168_N365_G0.5460.54
511_E549_T0.5460.54
110_D444_E0.5460.54
365_G375_Y0.5460.54
189_P365_G0.5450.54
401_V404_L0.5450.54
354_G365_G0.5450.54
284_Y326_T0.5450.54
435_R543_K0.5450.54
414_D418_I0.5440.54
17_I183_Y0.5440.54
174_M189_P0.5440.54
520_I532_T0.5440.54
93_I156_F0.5430.54
277_V307_L0.5430.54
300_Y465_P0.5430.54
137_Y161_I0.5420.53
391_T498_T0.5420.53
188_L198_A0.5420.53
279_G356_V0.5420.53
363_S378_I0.5400.53
196_E365_G0.5390.53
178_T195_A0.5380.53
365_G377_P0.5380.53
200_I369_A0.5370.53
177_I197_N0.5370.53
153_S363_S0.5370.53
575_P580_K0.5370.53
470_G507_I0.5370.53
474_F550_P0.5370.53
524_K530_I0.5350.53
291_S361_T0.5340.52
178_T183_Y0.5340.52
181_C320_Y0.5340.52
24_K235_E0.5340.52
173_L373_N0.5340.52
504_V523_I0.5340.52
20_K244_P0.5330.52
285_I302_F0.5330.52
455_L480_T0.5330.52
494_P561_A0.5320.52
466_I552_S0.5320.52
480_T564_L0.5320.52
385_A496_V0.5320.52
286_I350_A0.5310.52
254_I555_I0.5310.52
550_P556_P0.5290.52
141_S167_I0.5290.52
490_L574_T0.5290.52
438_E444_E0.5280.52
92_K134_S0.5280.52
246_F364_V0.5280.52
285_I514_D0.5270.51
361_T496_V0.5260.51
6_A486_Q0.5260.51
415_R418_I0.5250.51
347_I357_I0.5250.51
458_S516_Y0.5250.51
93_I132_E0.5240.51
552_S555_I0.5240.51
361_T528_D0.5230.51
169_S219_I0.5230.51
245_H570_L0.5230.51
482_A509_P0.5230.51
151_I171_Q0.5230.51
400_K548_L0.5220.51
408_L413_N0.5220.51
40_D114_K0.5220.51
305_I421_L0.5210.51
295_G466_I0.5210.51
305_I404_L0.5210.51
8_V163_K0.5210.51
516_Y520_I0.5200.50
177_I212_N0.5200.50
74_S86_L0.5200.50
490_L502_Y0.5190.50
554_V557_L0.5190.50
262_F549_T0.5160.50
369_A372_S0.5160.50
465_P509_P0.5150.50
293_H561_A0.5140.50
537_G541_S0.5140.50
187_D581_A0.5140.50
87_T159_I0.5140.50
173_L201_M0.5140.50
171_Q203_E0.5130.50
543_K553_N0.5130.50
463_N511_E0.5130.50
366_S369_A0.5120.49
92_K116_H0.5120.49
46_K63_A0.5120.49
236_E244_P0.5120.49
499_N521_R0.5120.49
301_Y305_I0.5120.49
265_L377_P0.5110.49
112_I121_T0.5110.49
133_N144_V0.5110.49
435_R542_I0.5110.49
131_L154_L0.5100.49
243_F440_E0.5100.49
463_N510_V0.5090.49
542_I552_S0.5090.49
244_P444_E0.5080.49
308_N324_N0.5080.49
291_S395_T0.5080.49
294_A496_V0.5080.49
294_A388_A0.5080.49
5_F25_L0.5070.49
232_K235_E0.5070.49
573_D580_K0.5070.49
453_E501_G0.5070.49
290_T494_P0.5070.49
138_L163_K0.5060.49
407_G414_D0.5060.49
346_S530_I0.5060.49
498_T523_I0.5050.48
525_E574_T0.5050.48
141_S145_M0.5050.48
11_D194_F0.5050.48
43_L157_V0.5040.48
305_I505_I0.5040.48
234_K365_G0.5040.48
93_I164_I0.5020.48
10_K64_R0.5020.48
42_S117_K0.5020.48
511_E535_E0.5020.48
521_R525_E0.5010.48
146_K219_I0.5010.48
392_F456_Y0.5010.48
155_V196_E0.5010.48
451_D500_K0.5010.48
283_V324_N0.5010.48
297_I313_S0.5010.48
345_R518_K0.5000.48
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4amvA 2 0.988 100 0.331 Contact Map
2zj3A 2 0.5873 100 0.594 Contact Map
3tbfA 2 0.5771 100 0.596 Contact Map
1moqA 2 0.589 100 0.598 Contact Map
4s1wA 2 0.5616 100 0.603 Contact Map
2pocA 4 0.5651 100 0.603 Contact Map
3knzA 2 0.536 100 0.636 Contact Map
1j5xA 2 0.5411 100 0.638 Contact Map
2amlA 2 0.5942 100 0.642 Contact Map
3g68A 3 0.5753 100 0.643 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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