Q97YQ6 - SULSO - GREMLIN Contacts

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Q97YQ6 - Glutamine-fructose-6-phosphate transaminase (Isomerizing) (GlmS-2)

UniProt:	Q97YQ6	Sequences: MGGIFAFVCKDSIDVSIINKGLKKLIYRGYDSAGIAYLEDDSLVIKKILGNISKNEISVSDKARVAIGHTRYASRGWPTLENAHPLTDCNGKIAVVMDGILDDYEKIREDLIAKGHKFVSTTDAEVIPHLLENSTNYLNSSLNVMKRVKGIYSLVFVTIDIDKIFAINSGQPLMIGITQECKYVSSDLPSLSGFAENAIIMPENTVAVISWNDVQVYNIEGNEVKPEIKRVKYKEEIAEKGGFPHFMLKEIYDIPQALINSFNSLMEKYLSLASMIVYGAKNVYIIGNGTSLHAGFISSYYFSEISLNVNVVSAAEFPYYALKNVTTGSVIIAISQSGETSDVIRSIKMAKQRGAVILGITNSVGSRLALESNVYLPITAGPEMAVPATKTFTSTIVVLKVLSLYTGLHSGKNDRSEISSLKSEIEELAKQLMVRLPEMEKEAEKLAPKLDKESLYISSSGINYPIALEGALKFKEASMTHAEGIQLGELLHGPIVLTNKGYPVILIKPVEAEDLYNKVIRSIKERGDVIVTVAEDGDMKSIKATRDLTPISNVIPLHLLAYKLGVRKGLPIDTPPGLVKAVIV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	584 (580)
Sequences:	3769 (2062)
Seq/√Len:	85.6

ECOLI - GLMS
BACSU - GLMS
HALSA - GLMS
SULSO - Q97YQ6 Q980D3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
110_D	147_R	4.924	1.00
114_K	133_N	4.350	1.00
281_K	328_G	4.036	1.00
359_G	372_S	4.019	1.00
218_N	222_N	3.920	1.00
258_L	432_L	3.830	1.00
23_K	56_E	3.538	1.00
285_I	295_G	3.494	1.00
141_S	165_F	3.400	1.00
127_I	148_V	3.271	1.00
205_T	226_P	3.265	1.00
388_A	391_T	3.260	1.00
348_K	371_E	3.227	1.00
136_N	139_N	3.221	1.00
18_I	66_A	3.124	1.00
131_L	144_V	3.083	1.00
256_Q	260_N	3.080	1.00
51_N	574_T	3.043	1.00
440_E	563_K	2.916	1.00
197_N	230_R	2.714	1.00
258_L	397_V	2.696	1.00
166_A	184_V	2.665	1.00
92_K	160_D	2.637	1.00
89_C	116_H	2.619	1.00
116_H	132_E	2.578	1.00
48_I	58_S	2.571	1.00
138_L	217_Y	2.520	1.00
116_H	133_N	2.489	1.00
127_I	154_L	2.489	1.00
163_K	208_V	2.481	1.00
334_I	399_L	2.442	1.00
166_A	207_A	2.431	1.00
215_Q	223_E	2.389	1.00
137_Y	165_F	2.385	1.00
116_H	129_H	2.376	1.00
433_M	438_E	2.373	1.00
175_I	207_A	2.359	1.00
432_L	555_I	2.348	1.00
95_V	128_P	2.333	1.00
281_K	326_T	2.224	1.00
48_I	80_L	2.219	1.00
175_I	214_V	2.212	1.00
471_A	482_A	2.201	1.00
81_E	121_T	2.167	1.00
89_C	132_E	2.151	1.00
131_L	156_F	2.143	1.00
178_T	181_C	2.113	1.00
177_I	199_I	2.104	1.00
428_L	551_I	2.104	1.00
404_L	421_L	2.087	1.00
53_S	57_I	2.059	1.00
295_G	334_I	2.057	1.00
252_Y	440_E	2.052	1.00
302_F	309_V	2.051	1.00
302_F	406_T	2.047	1.00
20_K	193_G	2.012	1.00
137_Y	158_T	1.995	1.00
261_S	378_I	1.994	1.00
155_V	164_I	1.980	1.00
408_L	418_I	1.975	1.00
566_V	572_I	1.974	1.00
149_K	514_D	1.966	1.00
302_F	403_S	1.959	1.00
417_E	420_S	1.942	1.00
182_K	214_V	1.913	1.00
270_L	273_A	1.907	1.00
108_R	112_I	1.901	1.00
506_L	520_I	1.879	1.00
95_V	124_A	1.865	1.00
313_S	486_Q	1.863	1.00
333_A	347_I	1.863	1.00
487_L	516_Y	1.856	1.00
468_L	484_G	1.843	1.00
155_V	184_V	1.842	1.00
47_K	80_L	1.838	1.00
202_P	226_P	1.837	1.00
138_L	208_V	1.834	1.00
392_F	466_I	1.833	1.00
177_I	214_V	1.827	1.00
37_Y	63_A	1.822	1.00
434_V	438_E	1.820	1.00
282_N	310_N	1.815	1.00
197_N	228_I	1.809	1.00
349_M	352_Q	1.806	1.00
145_M	148_V	1.801	1.00
141_S	156_F	1.794	1.00
312_V	320_Y	1.787	1.00
92_K	159_I	1.785	1.00
162_D	211_W	1.778	1.00
290_T	388_A	1.762	1.00
435_R	552_S	1.752	1.00
131_L	141_S	1.736	1.00
11_D	181_C	1.733	1.00
542_I	553_N	1.723	1.00
304_E	322_L	1.722	1.00
470_G	557_L	1.720	1.00
505_I	560_L	1.719	1.00
325_V	355_A	1.716	1.00
49_L	79_T	1.715	1.00
18_I	68_G	1.713	1.00
54_K	57_I	1.704	1.00
424_E	431_Q	1.683	1.00
87_T	94_A	1.680	1.00
357_I	372_S	1.666	1.00
58_S	80_L	1.661	1.00
51_N	571_P	1.654	1.00
8_V	211_W	1.652	1.00
257_A	394_S	1.643	1.00
414_D	417_E	1.635	1.00
43_L	94_A	1.628	1.00
280_A	330_V	1.627	1.00
292_L	296_F	1.626	1.00
326_T	329_S	1.621	1.00
448_P	567_R	1.619	1.00
196_E	230_R	1.618	1.00
177_I	182_K	1.618	1.00
139_N	142_L	1.613	1.00
434_V	536_D	1.603	1.00
8_V	65_V	1.599	1.00
208_V	215_Q	1.595	1.00
424_E	546_R	1.580	1.00
243_F	252_Y	1.577	1.00
36_A	94_A	1.576	1.00
93_I	158_T	1.571	1.00
534_A	541_S	1.566	1.00
144_V	148_V	1.560	1.00
537_G	544_A	1.560	1.00
361_T	369_A	1.555	1.00
182_K	213_D	1.550	1.00
378_I	394_S	1.539	1.00
216_V	226_P	1.539	1.00
317_F	325_V	1.538	1.00
19_N	35_I	1.511	1.00
93_I	137_Y	1.510	1.00
15_V	35_I	1.510	1.00
331_I	355_A	1.510	1.00
563_K	567_R	1.509	1.00
441_K	444_E	1.503	1.00
95_V	127_I	1.500	0.99
335_S	368_L	1.496	0.99
270_L	274_S	1.493	0.99
245_H	562_Y	1.484	0.99
109_E	113_A	1.484	0.99
166_A	175_I	1.483	0.99
427_E	431_Q	1.481	0.99
106_K	149_K	1.473	0.99
163_K	210_S	1.470	0.99
405_Y	409_H	1.466	0.99
210_S	213_D	1.461	0.99
283_V	332_I	1.449	0.99
199_I	214_V	1.448	0.99
169_S	204_N	1.445	0.99
104_Y	108_R	1.443	0.99
364_V	377_P	1.434	0.99
458_S	523_I	1.430	0.99
46_K	58_S	1.428	0.99
188_L	200_I	1.410	0.99
140_S	144_V	1.400	0.99
464_Y	468_L	1.385	0.99
39_E	42_S	1.385	0.99
49_L	78_P	1.385	0.99
458_S	506_L	1.382	0.99
520_I	530_I	1.372	0.99
53_S	56_E	1.361	0.99
145_M	167_I	1.356	0.99
20_K	23_K	1.353	0.99
87_T	91_G	1.349	0.99
36_A	43_L	1.348	0.99
431_Q	545_T	1.346	0.99
301_Y	400_K	1.325	0.99
299_S	310_N	1.321	0.99
351_K	373_N	1.317	0.99
369_A	375_Y	1.317	0.99
466_I	554_V	1.308	0.99
420_S	546_R	1.308	0.99
199_I	216_V	1.307	0.99
244_P	566_V	1.306	0.99
284_Y	317_F	1.306	0.99
142_L	217_Y	1.305	0.99
138_L	142_L	1.292	0.98
404_L	418_I	1.284	0.98
344_I	348_K	1.278	0.98
108_R	118_F	1.277	0.98
201_M	207_A	1.266	0.98
259_I	433_M	1.257	0.98
341_S	345_R	1.239	0.98
513_E	538_D	1.237	0.98
158_T	161_I	1.231	0.98
360_I	399_L	1.229	0.98
110_D	133_N	1.227	0.98
446_L	531_V	1.222	0.98
109_E	112_I	1.222	0.98
156_F	165_F	1.221	0.98
533_V	542_I	1.215	0.98
359_G	368_L	1.212	0.98
439_M	442_E	1.205	0.98
38_L	157_V	1.204	0.98
565_G	570_L	1.202	0.98
331_I	350_A	1.202	0.98
450_L	560_L	1.197	0.97
137_Y	141_S	1.194	0.97
118_F	126_V	1.191	0.97
430_K	433_M	1.188	0.97
347_I	368_L	1.187	0.97
276_I	356_V	1.186	0.97
560_L	564_L	1.179	0.97
92_K	132_E	1.179	0.97
261_S	398_V	1.176	0.97
498_T	528_D	1.175	0.97
283_V	330_V	1.169	0.97
138_L	206_V	1.167	0.97
376_L	398_V	1.155	0.97
9_C	13_I	1.155	0.97
15_V	63_A	1.150	0.97
208_V	217_Y	1.147	0.97
217_Y	223_E	1.146	0.97
305_I	403_S	1.143	0.97
233_Y	238_A	1.140	0.97
407_G	413_N	1.136	0.97
240_K	574_T	1.135	0.97
248_L	252_Y	1.134	0.96
178_T	182_K	1.132	0.96
7_F	13_I	1.129	0.96
431_Q	552_S	1.128	0.96
545_T	552_S	1.128	0.96
89_C	129_H	1.125	0.96
332_I	402_L	1.124	0.96
105_E	109_E	1.124	0.96
36_A	45_I	1.120	0.96
42_S	159_I	1.119	0.96
155_V	166_A	1.118	0.96
298_S	399_L	1.114	0.96
449_K	529_V	1.111	0.96
458_S	490_L	1.106	0.96
152_Y	169_S	1.104	0.96
453_E	568_K	1.102	0.96
509_P	553_N	1.099	0.96
413_N	418_I	1.099	0.96
511_E	547_D	1.095	0.96
282_N	326_T	1.092	0.96
131_L	140_S	1.091	0.96
176_G	195_A	1.091	0.96
455_L	505_I	1.091	0.96
435_R	439_M	1.088	0.96
177_I	228_I	1.087	0.96
293_H	296_F	1.087	0.96
92_K	158_T	1.085	0.95
254_I	393_T	1.084	0.95
49_L	77_W	1.082	0.95
417_E	421_L	1.080	0.95
108_R	126_V	1.079	0.95
440_E	444_E	1.079	0.95
534_A	538_D	1.077	0.95
10_K	211_W	1.073	0.95
165_F	208_V	1.067	0.95
282_N	308_N	1.067	0.95
333_A	357_I	1.066	0.95
378_I	395_T	1.066	0.95
329_S	355_A	1.064	0.95
65_V	164_I	1.062	0.95
143_N	146_K	1.060	0.95
6_A	184_V	1.058	0.95
318_P	345_R	1.054	0.95
49_L	54_K	1.048	0.95
504_V	528_D	1.048	0.95
38_L	65_V	1.041	0.94
356_V	373_N	1.038	0.94
444_E	448_P	1.033	0.94
447_A	560_L	1.033	0.94
439_M	443_A	1.032	0.94
356_V	374_V	1.032	0.94
508_K	513_E	1.031	0.94
428_L	552_S	1.030	0.94
333_A	372_S	1.028	0.94
298_S	302_F	1.026	0.94
303_S	320_Y	1.023	0.94
432_L	551_I	1.021	0.94
19_N	56_E	1.020	0.94
283_V	307_L	1.020	0.94
139_N	143_N	1.018	0.94
521_R	524_K	1.014	0.94
11_D	183_Y	1.013	0.93
283_V	309_V	1.013	0.93
200_I	229_K	1.011	0.93
571_P	574_T	1.008	0.93
155_V	209_I	1.002	0.93
538_D	541_S	1.001	0.93
559_L	563_K	1.000	0.93
248_L	440_E	0.992	0.93
245_H	248_L	0.990	0.93
244_P	248_L	0.988	0.93
535_E	544_A	0.985	0.93
134_S	139_N	0.984	0.92
23_K	52_I	0.984	0.92
90_N	132_E	0.981	0.92
266_M	426_E	0.980	0.92
271_S	274_S	0.979	0.92
189_P	192_S	0.976	0.92
417_E	546_R	0.975	0.92
490_L	495_I	0.970	0.92
349_M	353_R	0.967	0.92
442_E	445_K	0.966	0.92
265_L	401_V	0.965	0.92
77_W	527_G	0.964	0.92
302_F	402_L	0.961	0.92
463_N	507_I	0.958	0.91
445_K	448_P	0.955	0.91
47_K	87_T	0.954	0.91
333_A	350_A	0.953	0.91
456_Y	502_Y	0.951	0.91
523_I	530_I	0.950	0.91
8_V	162_D	0.949	0.91
407_G	418_I	0.949	0.91
392_F	465_P	0.948	0.91
184_V	209_I	0.947	0.91
51_N	240_K	0.946	0.91
523_I	528_D	0.944	0.91
397_V	551_I	0.943	0.91
284_Y	329_S	0.942	0.91
49_L	80_L	0.940	0.91
65_V	162_D	0.939	0.91
306_S	403_S	0.938	0.91
229_K	365_G	0.938	0.91
405_Y	408_L	0.936	0.90
182_K	212_N	0.936	0.90
137_Y	156_F	0.936	0.90
454_S	502_Y	0.935	0.90
94_A	157_V	0.933	0.90
39_E	44_V	0.931	0.90
168_N	348_K	0.929	0.90
287_G	291_S	0.926	0.90
15_V	37_Y	0.926	0.90
111_L	118_F	0.924	0.90
57_I	61_D	0.921	0.90
77_W	121_T	0.920	0.90
424_E	427_E	0.919	0.90
110_D	114_K	0.919	0.90
380_A	394_S	0.918	0.90
307_L	410_S	0.917	0.90
112_I	117_K	0.915	0.89
285_I	309_V	0.913	0.89
369_A	377_P	0.913	0.89
142_L	206_V	0.911	0.89
12_S	64_R	0.911	0.89
285_I	311_V	0.908	0.89
207_A	214_V	0.908	0.89
344_I	367_R	0.905	0.89
401_V	422_K	0.905	0.89
385_A	391_T	0.904	0.89
157_V	164_I	0.903	0.89
168_N	203_E	0.903	0.89
465_P	494_P	0.902	0.89
297_I	466_I	0.900	0.89
507_I	557_L	0.898	0.89
121_T	521_R	0.897	0.89
293_H	468_L	0.896	0.88
152_Y	219_I	0.895	0.88
127_I	144_V	0.894	0.88
48_I	54_K	0.893	0.88
151_I	170_G	0.889	0.88
129_H	132_E	0.889	0.88
454_S	481_H	0.889	0.88
272_L	275_M	0.887	0.88
323_K	349_M	0.883	0.88
444_E	563_K	0.880	0.88
199_I	228_I	0.877	0.87
306_S	410_S	0.875	0.87
262_F	425_I	0.873	0.87
181_C	195_A	0.872	0.87
81_E	119_V	0.871	0.87
179_Q	197_N	0.871	0.87
134_S	140_S	0.868	0.87
245_H	566_V	0.867	0.87
216_V	224_V	0.866	0.87
24_K	193_G	0.861	0.86
457_I	474_F	0.861	0.86
127_I	145_M	0.861	0.86
161_I	165_F	0.859	0.86
415_R	419_S	0.859	0.86
474_F	480_T	0.857	0.86
457_I	557_L	0.856	0.86
102_D	515_L	0.855	0.86
231_V	365_G	0.853	0.86
453_E	499_N	0.851	0.86
252_Y	436_L	0.850	0.86
379_T	382_P	0.850	0.86
465_P	484_G	0.848	0.86
282_N	329_S	0.847	0.86
519_V	522_S	0.846	0.85
195_A	230_R	0.845	0.85
280_A	356_V	0.844	0.85
45_I	87_T	0.840	0.85
427_E	430_K	0.839	0.85
93_I	128_P	0.836	0.85
247_M	385_A	0.836	0.85
385_A	494_P	0.836	0.85
56_E	60_S	0.835	0.85
19_N	59_V	0.834	0.85
290_T	294_A	0.832	0.84
385_A	392_F	0.832	0.84
138_L	215_Q	0.832	0.84
281_K	329_S	0.832	0.84
279_G	328_G	0.830	0.84
11_D	17_I	0.826	0.84
272_L	376_L	0.826	0.84
135_T	139_N	0.824	0.84
420_S	424_E	0.824	0.84
498_T	504_V	0.824	0.84
52_I	68_G	0.823	0.84
314_A	523_I	0.823	0.84
393_T	555_I	0.822	0.84
534_A	539_M	0.821	0.84
276_I	279_G	0.820	0.84
552_S	556_P	0.819	0.84
17_I	194_F	0.819	0.84
277_V	406_T	0.818	0.83
188_L	192_S	0.817	0.83
285_I	399_L	0.816	0.83
296_F	311_V	0.815	0.83
175_I	201_M	0.815	0.83
256_Q	433_M	0.815	0.83
37_Y	66_A	0.812	0.83
185_S	190_S	0.811	0.83
347_I	372_S	0.810	0.83
119_V	129_H	0.809	0.83
52_I	59_V	0.808	0.83
280_A	329_S	0.806	0.83
450_L	455_L	0.803	0.82
184_V	207_A	0.803	0.82
392_F	554_V	0.799	0.82
359_G	375_Y	0.795	0.82
298_S	403_S	0.795	0.82
129_H	133_N	0.795	0.82
455_L	474_F	0.794	0.82
239_E	246_F	0.794	0.82
182_K	209_I	0.791	0.81
536_D	544_A	0.791	0.81
463_N	549_T	0.789	0.81
364_V	375_Y	0.789	0.81
299_S	303_S	0.786	0.81
360_I	402_L	0.784	0.81
471_A	484_G	0.783	0.81
89_C	133_N	0.783	0.81
364_V	369_A	0.782	0.81
248_L	563_K	0.781	0.81
458_S	467_A	0.780	0.80
322_L	353_R	0.779	0.80
7_F	17_I	0.778	0.80
431_Q	435_R	0.774	0.80
196_E	234_K	0.773	0.80
424_E	548_L	0.773	0.80
158_T	165_F	0.773	0.80
292_L	313_S	0.770	0.80
248_L	562_Y	0.770	0.80
175_I	199_I	0.769	0.80
446_L	450_L	0.768	0.79
258_L	378_I	0.768	0.79
551_I	556_P	0.767	0.79
278_Y	409_H	0.766	0.79
512_A	547_D	0.765	0.79
243_F	248_L	0.764	0.79
136_N	163_K	0.763	0.79
470_G	477_A	0.762	0.79
423_S	427_E	0.761	0.79
290_T	496_V	0.761	0.79
12_S	62_K	0.758	0.79
474_F	478_S	0.756	0.78
534_A	537_G	0.756	0.78
470_G	554_V	0.756	0.78
564_L	568_K	0.752	0.78
47_K	81_E	0.751	0.78
118_F	130_L	0.743	0.77
286_I	317_F	0.743	0.77
499_N	528_D	0.743	0.77
261_S	394_S	0.742	0.77
45_I	94_A	0.741	0.77
286_I	331_I	0.739	0.77
166_A	201_M	0.739	0.77
467_A	507_I	0.739	0.77
506_L	516_Y	0.737	0.77
443_A	559_L	0.737	0.77
421_L	548_L	0.736	0.76
325_V	329_S	0.735	0.76
191_L	198_A	0.734	0.76
162_D	210_S	0.733	0.76
164_I	184_V	0.733	0.76
65_V	157_V	0.732	0.76
111_L	115_G	0.732	0.76
500_K	527_G	0.732	0.76
296_F	468_L	0.731	0.76
202_P	205_T	0.730	0.76
388_A	496_V	0.729	0.76
565_G	572_I	0.729	0.76
13_I	16_S	0.727	0.76
301_Y	403_S	0.726	0.75
154_L	167_I	0.726	0.75
350_A	355_A	0.726	0.75
163_K	166_A	0.725	0.75
330_V	358_L	0.724	0.75
43_L	87_T	0.719	0.75
301_Y	396_I	0.719	0.75
110_D	113_A	0.718	0.75
391_T	581_A	0.718	0.75
443_A	560_L	0.716	0.74
205_T	218_N	0.716	0.74
257_A	261_S	0.715	0.74
111_L	130_L	0.715	0.74
206_V	217_Y	0.713	0.74
142_L	221_G	0.713	0.74
77_W	81_E	0.713	0.74
285_I	332_I	0.712	0.74
201_M	205_T	0.710	0.74
450_L	564_L	0.710	0.74
248_L	559_L	0.709	0.74
91_G	132_E	0.708	0.74
456_Y	499_N	0.707	0.74
402_L	406_T	0.706	0.73
421_L	424_E	0.705	0.73
294_A	399_L	0.705	0.73
333_A	343_V	0.704	0.73
175_I	216_V	0.700	0.73
455_L	564_L	0.699	0.73
270_L	275_M	0.697	0.73
485_I	494_P	0.697	0.73
298_S	301_Y	0.697	0.73
408_L	415_R	0.695	0.72
360_I	378_I	0.695	0.72
93_I	160_D	0.694	0.72
257_A	380_A	0.693	0.72
422_K	426_E	0.693	0.72
149_K	169_S	0.692	0.72
456_Y	572_I	0.692	0.72
7_F	181_C	0.691	0.72
192_S	233_Y	0.689	0.72
8_V	209_I	0.688	0.72
192_S	195_A	0.687	0.71
452_K	529_V	0.687	0.71
490_L	523_I	0.686	0.71
333_A	359_G	0.684	0.71
93_I	140_S	0.682	0.71
318_P	515_L	0.682	0.71
6_A	155_V	0.682	0.71
89_C	117_K	0.681	0.71
12_S	15_V	0.681	0.71
96_V	174_M	0.681	0.71
22_L	33_A	0.680	0.71
396_I	551_I	0.679	0.71
12_S	16_S	0.678	0.70
299_S	311_V	0.675	0.70
138_L	165_F	0.674	0.70
457_I	561_A	0.674	0.70
233_Y	365_G	0.674	0.70
221_G	224_V	0.673	0.70
46_K	59_V	0.671	0.70
87_T	129_H	0.671	0.70
423_S	426_E	0.670	0.70
465_P	468_L	0.670	0.70
64_R	211_W	0.669	0.69
302_F	306_S	0.669	0.69
134_S	143_N	0.666	0.69
48_I	52_I	0.665	0.69
508_K	520_I	0.664	0.69
396_I	400_K	0.664	0.69
413_N	417_E	0.663	0.69
513_E	541_S	0.662	0.69
193_G	196_E	0.662	0.69
348_K	367_R	0.660	0.68
218_N	221_G	0.660	0.68
351_K	371_E	0.660	0.68
368_L	377_P	0.660	0.68
393_T	551_I	0.659	0.68
143_N	147_R	0.657	0.68
1_M	4_I	0.656	0.68
397_V	425_I	0.655	0.68
393_T	554_V	0.655	0.68
444_E	567_R	0.654	0.68
418_I	422_K	0.653	0.68
100_I	518_K	0.653	0.68
262_F	397_V	0.653	0.68
454_S	485_I	0.652	0.67
231_V	238_A	0.650	0.67
91_G	119_V	0.650	0.67
171_Q	341_S	0.649	0.67
107_I	148_V	0.649	0.67
313_S	488_G	0.648	0.67
478_S	570_L	0.647	0.67
260_N	378_I	0.645	0.67
376_L	402_L	0.644	0.66
127_I	156_F	0.644	0.66
18_I	35_I	0.642	0.66
174_M	344_I	0.641	0.66
435_R	443_A	0.641	0.66
403_S	407_G	0.641	0.66
404_L	407_G	0.639	0.66
203_E	348_K	0.637	0.66
47_K	119_V	0.637	0.66
427_E	545_T	0.636	0.66
105_E	108_R	0.636	0.66
400_K	421_L	0.635	0.65
510_V	535_E	0.634	0.65
175_I	184_V	0.632	0.65
291_S	334_I	0.632	0.65
258_L	435_R	0.632	0.65
392_F	494_P	0.631	0.65
218_N	224_V	0.630	0.65
397_V	428_L	0.630	0.65
183_Y	194_F	0.629	0.65
532_T	541_S	0.628	0.65
268_K	273_A	0.627	0.64
447_A	567_R	0.626	0.64
463_N	553_N	0.626	0.64
174_M	191_L	0.625	0.64
392_F	463_N	0.625	0.64
192_S	196_E	0.625	0.64
200_I	385_A	0.625	0.64
455_L	482_A	0.624	0.64
264_S	379_T	0.623	0.64
431_Q	434_V	0.623	0.64
332_I	358_L	0.620	0.64
313_S	490_L	0.619	0.63
247_M	477_A	0.618	0.63
57_I	60_S	0.617	0.63
418_I	421_L	0.617	0.63
136_N	161_I	0.617	0.63
407_G	411_G	0.615	0.63
174_M	188_L	0.615	0.63
367_R	371_E	0.614	0.63
465_P	471_A	0.614	0.63
535_E	549_T	0.614	0.63
180_E	183_Y	0.613	0.63
130_L	148_V	0.613	0.63
173_L	184_V	0.612	0.63
97_M	171_Q	0.612	0.63
443_A	556_P	0.611	0.62
365_G	369_A	0.609	0.62
291_S	490_L	0.609	0.62
293_H	361_T	0.608	0.62
304_E	417_E	0.606	0.62
424_E	428_L	0.606	0.62
501_G	527_G	0.606	0.62
323_K	388_A	0.604	0.62
495_I	498_T	0.604	0.62
510_V	513_E	0.603	0.61
170_G	511_E	0.603	0.61
63_A	66_A	0.600	0.61
450_L	505_I	0.600	0.61
67_I	155_V	0.600	0.61
457_I	487_L	0.599	0.61
195_A	228_I	0.599	0.61
510_V	538_D	0.598	0.61
495_I	528_D	0.597	0.61
183_Y	191_L	0.596	0.61
148_V	152_Y	0.596	0.61
286_I	333_A	0.594	0.60
35_I	59_V	0.594	0.60
533_V	553_N	0.594	0.60
233_Y	364_V	0.593	0.60
303_S	311_V	0.593	0.60
315_A	488_G	0.593	0.60
388_A	528_D	0.592	0.60
451_D	568_K	0.592	0.60
495_I	499_N	0.592	0.60
455_L	502_Y	0.592	0.60
545_T	548_L	0.590	0.60
297_I	550_P	0.590	0.60
333_A	368_L	0.589	0.60
456_Y	498_T	0.589	0.60
452_K	503_P	0.589	0.60
428_L	548_L	0.588	0.59
102_D	345_R	0.587	0.59
170_G	203_E	0.586	0.59
384_M	574_T	0.585	0.59
508_K	516_Y	0.583	0.59
79_T	83_A	0.582	0.59
171_Q	523_I	0.582	0.59
275_M	552_S	0.582	0.59
90_N	116_H	0.581	0.59
141_S	144_V	0.580	0.58
95_V	154_L	0.580	0.58
24_K	239_E	0.579	0.58
456_Y	528_D	0.579	0.58
234_K	237_I	0.579	0.58
395_T	399_L	0.577	0.58
266_M	422_K	0.577	0.58
463_N	509_P	0.576	0.58
22_L	68_G	0.576	0.58
35_I	68_G	0.576	0.58
494_P	507_I	0.575	0.58
291_S	311_V	0.574	0.58
244_P	574_T	0.574	0.58
96_V	277_V	0.571	0.57
16_S	56_E	0.571	0.57
205_T	224_V	0.571	0.57
533_V	557_L	0.570	0.57
104_Y	521_R	0.570	0.57
297_I	300_Y	0.569	0.57
322_L	512_A	0.568	0.57
511_E	544_A	0.567	0.57
108_R	128_P	0.567	0.57
15_V	19_N	0.567	0.57
515_L	518_K	0.566	0.57
18_I	37_Y	0.566	0.57
277_V	280_A	0.566	0.57
68_G	335_S	0.563	0.56
368_L	372_S	0.563	0.56
118_F	129_H	0.563	0.56
167_I	204_N	0.562	0.56
579_V	583_I	0.561	0.56
16_S	20_K	0.561	0.56
298_S	421_L	0.559	0.56
296_F	461_G	0.558	0.56
27_Y	187_D	0.557	0.55
6_A	354_G	0.557	0.55
507_I	553_N	0.555	0.55
210_S	214_V	0.555	0.55
474_F	564_L	0.555	0.55
293_H	395_T	0.555	0.55
465_P	482_A	0.555	0.55
471_A	496_V	0.554	0.55
432_L	436_L	0.554	0.55
142_L	146_K	0.553	0.55
407_G	412_K	0.552	0.55
284_Y	310_N	0.552	0.55
69_H	84_H	0.552	0.55
319_Y	345_R	0.552	0.55
161_I	208_V	0.551	0.55
291_S	391_T	0.551	0.55
287_G	311_V	0.550	0.55
257_A	265_L	0.550	0.55
13_I	17_I	0.550	0.55
210_S	215_Q	0.549	0.54
351_K	357_I	0.548	0.54
80_L	83_A	0.548	0.54
10_K	180_E	0.547	0.54
388_A	498_T	0.547	0.54
283_V	302_F	0.546	0.54
168_N	365_G	0.546	0.54
511_E	549_T	0.546	0.54
110_D	444_E	0.546	0.54
365_G	375_Y	0.546	0.54
189_P	365_G	0.545	0.54
401_V	404_L	0.545	0.54
354_G	365_G	0.545	0.54
284_Y	326_T	0.545	0.54
435_R	543_K	0.545	0.54
414_D	418_I	0.544	0.54
17_I	183_Y	0.544	0.54
174_M	189_P	0.544	0.54
520_I	532_T	0.544	0.54
93_I	156_F	0.543	0.54
277_V	307_L	0.543	0.54
300_Y	465_P	0.543	0.54
137_Y	161_I	0.542	0.53
391_T	498_T	0.542	0.53
188_L	198_A	0.542	0.53
279_G	356_V	0.542	0.53
363_S	378_I	0.540	0.53
196_E	365_G	0.539	0.53
178_T	195_A	0.538	0.53
365_G	377_P	0.538	0.53
200_I	369_A	0.537	0.53
177_I	197_N	0.537	0.53
153_S	363_S	0.537	0.53
575_P	580_K	0.537	0.53
470_G	507_I	0.537	0.53
474_F	550_P	0.537	0.53
524_K	530_I	0.535	0.53
291_S	361_T	0.534	0.52
178_T	183_Y	0.534	0.52
181_C	320_Y	0.534	0.52
24_K	235_E	0.534	0.52
173_L	373_N	0.534	0.52
504_V	523_I	0.534	0.52
20_K	244_P	0.533	0.52
285_I	302_F	0.533	0.52
455_L	480_T	0.533	0.52
494_P	561_A	0.532	0.52
466_I	552_S	0.532	0.52
480_T	564_L	0.532	0.52
385_A	496_V	0.532	0.52
286_I	350_A	0.531	0.52
254_I	555_I	0.531	0.52
550_P	556_P	0.529	0.52
141_S	167_I	0.529	0.52
490_L	574_T	0.529	0.52
438_E	444_E	0.528	0.52
92_K	134_S	0.528	0.52
246_F	364_V	0.528	0.52
285_I	514_D	0.527	0.51
361_T	496_V	0.526	0.51
6_A	486_Q	0.526	0.51
415_R	418_I	0.525	0.51
347_I	357_I	0.525	0.51
458_S	516_Y	0.525	0.51
93_I	132_E	0.524	0.51
552_S	555_I	0.524	0.51
361_T	528_D	0.523	0.51
169_S	219_I	0.523	0.51
245_H	570_L	0.523	0.51
482_A	509_P	0.523	0.51
151_I	171_Q	0.523	0.51
400_K	548_L	0.522	0.51
408_L	413_N	0.522	0.51
40_D	114_K	0.522	0.51
305_I	421_L	0.521	0.51
295_G	466_I	0.521	0.51
305_I	404_L	0.521	0.51
8_V	163_K	0.521	0.51
516_Y	520_I	0.520	0.50
177_I	212_N	0.520	0.50
74_S	86_L	0.520	0.50
490_L	502_Y	0.519	0.50
554_V	557_L	0.519	0.50
262_F	549_T	0.516	0.50
369_A	372_S	0.516	0.50
465_P	509_P	0.515	0.50
293_H	561_A	0.514	0.50
537_G	541_S	0.514	0.50
187_D	581_A	0.514	0.50
87_T	159_I	0.514	0.50
173_L	201_M	0.514	0.50
171_Q	203_E	0.513	0.50
543_K	553_N	0.513	0.50
463_N	511_E	0.513	0.50
366_S	369_A	0.512	0.49
92_K	116_H	0.512	0.49
46_K	63_A	0.512	0.49
236_E	244_P	0.512	0.49
499_N	521_R	0.512	0.49
301_Y	305_I	0.512	0.49
265_L	377_P	0.511	0.49
112_I	121_T	0.511	0.49
133_N	144_V	0.511	0.49
435_R	542_I	0.511	0.49
131_L	154_L	0.510	0.49
243_F	440_E	0.510	0.49
463_N	510_V	0.509	0.49
542_I	552_S	0.509	0.49
244_P	444_E	0.508	0.49
308_N	324_N	0.508	0.49
291_S	395_T	0.508	0.49
294_A	496_V	0.508	0.49
294_A	388_A	0.508	0.49
5_F	25_L	0.507	0.49
232_K	235_E	0.507	0.49
573_D	580_K	0.507	0.49
453_E	501_G	0.507	0.49
290_T	494_P	0.507	0.49
138_L	163_K	0.506	0.49
407_G	414_D	0.506	0.49
346_S	530_I	0.506	0.49
498_T	523_I	0.505	0.48
525_E	574_T	0.505	0.48
141_S	145_M	0.505	0.48
11_D	194_F	0.505	0.48
43_L	157_V	0.504	0.48
305_I	505_I	0.504	0.48
234_K	365_G	0.504	0.48
93_I	164_I	0.502	0.48
10_K	64_R	0.502	0.48
42_S	117_K	0.502	0.48
511_E	535_E	0.502	0.48
521_R	525_E	0.501	0.48
146_K	219_I	0.501	0.48
392_F	456_Y	0.501	0.48
155_V	196_E	0.501	0.48
451_D	500_K	0.501	0.48
283_V	324_N	0.501	0.48
297_I	313_S	0.501	0.48
345_R	518_K	0.500	0.48

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4amvA	2	0.988	100	0.331	Contact Map
2zj3A	2	0.5873	100	0.594	Contact Map
3tbfA	2	0.5771	100	0.596	Contact Map
1moqA	2	0.589	100	0.598	Contact Map
4s1wA	2	0.5616	100	0.603	Contact Map
2pocA	4	0.5651	100	0.603	Contact Map
3knzA	2	0.536	100	0.636	Contact Map
1j5xA	2	0.5411	100	0.638	Contact Map
2amlA	2	0.5942	100	0.642	Contact Map
3g68A	3	0.5753	100	0.643	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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