GREMLIN Database
Q97YQ0 - Oligo/dipeptide transport, permease protein (DppB-1)
UniProt: Q97YQ0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 348 (307)
Sequences: 15782 (10243)
Seq/√Len: 584.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
83_Q87_D3.5001.00
34_Q88_K3.4871.00
83_Q91_I3.4041.00
94_Y98_R3.0031.00
90_F94_Y3.0001.00
22_L89_Y2.8581.00
69_E73_E2.8021.00
77_A82_N2.7621.00
39_K76_I2.6451.00
237_V264_V2.5961.00
23_T89_Y2.5611.00
126_N296_W2.5241.00
250_K256_A2.4631.00
133_T218_L2.4371.00
258_R262_R2.3801.00
301_L305_V2.2891.00
246_V264_V2.2811.00
86_I90_F2.2311.00
5_T9_K2.2201.00
119_I302_L2.1101.00
21_T323_T2.0881.00
189_F212_Y2.0421.00
115_E118_S2.0121.00
107_L119_I1.9991.00
277_I333_G1.9561.00
72_R76_I1.9251.00
189_F215_A1.9121.00
241_M264_V1.8991.00
240_I245_F1.8941.00
273_A340_L1.8931.00
183_A191_P1.8891.00
71_Y74_S1.8571.00
240_I243_E1.8381.00
255_P258_R1.8371.00
248_T252_R1.8311.00
137_V222_F1.8211.00
68_V71_Y1.8091.00
140_V144_I1.8011.00
74_S78_A1.7841.00
87_D91_I1.7801.00
257_S261_Y1.7741.00
114_R118_S1.7291.00
73_E76_I1.7291.00
18_L324_I1.7141.00
116_V317_G1.6801.00
274_T337_Y1.6711.00
95_N100_D1.6551.00
145_I159_I1.6481.00
73_E77_A1.6391.00
14_Y327_L1.6391.00
194_M296_W1.6351.00
91_I94_Y1.6151.00
12_L16_S1.6111.00
96_L101_F1.5941.00
246_V259_I1.5721.00
156_E234_R1.5701.00
180_A185_A1.5571.00
154_F158_V1.5571.00
19_L89_Y1.5321.00
155_W159_I1.5281.00
178_L220_T1.5261.00
19_L23_T1.5181.00
22_L92_Q1.5181.00
148_L155_W1.5121.00
117_S121_A1.5051.00
303_T318_I1.4961.00
41_I72_R1.4901.00
141_A144_I1.4831.00
114_R122_Y1.4721.00
119_I314_V1.4711.00
336_V339_L1.4711.00
252_R263_H1.4541.00
141_A226_V1.4431.00
306_A314_V1.4351.00
222_F226_V1.4321.00
254_L258_R1.4161.00
245_F267_S1.4161.00
181_A185_A1.4131.00
218_L222_F1.4091.00
173_W177_V1.4041.00
208_I212_Y1.4011.00
8_I12_L1.3871.00
129_L194_M1.3801.00
240_I246_V1.3781.00
91_I95_N1.3761.00
196_S209_S1.3761.00
138_F225_N1.3631.00
150_A237_V1.3501.00
126_N194_M1.3331.00
240_I268_G1.3291.00
270_P337_Y1.3261.00
302_L314_V1.3251.00
80_G83_Q1.3171.00
75_L79_Y1.3071.00
84_P87_D1.3001.00
147_L237_V1.2991.00
19_L93_M1.2831.00
142_G233_V1.2751.00
139_I276_A1.2671.00
244_D247_I1.2611.00
75_L78_A1.2421.00
177_V181_A1.2421.00
14_Y331_F1.2381.00
104_A311_D1.2341.00
181_A186_V1.2251.00
39_K42_N1.2241.00
129_L210_V1.2231.00
87_D90_F1.2221.00
169_I174_L1.2211.00
152_S156_E1.2181.00
233_V272_I1.2141.00
42_N72_R1.2131.00
23_T27_I1.2091.00
135_T276_A1.2091.00
146_G233_V1.1951.00
103_T115_E1.1951.00
146_G150_A1.1911.00
18_L327_L1.1861.00
150_A238_T1.1831.00
22_L320_Y1.1781.00
4_T7_M1.1511.00
80_G91_I1.1371.00
166_H227_G1.1351.00
122_Y125_P1.1301.00
23_T85_I1.1241.00
335_L339_L1.1171.00
234_R238_T1.1131.00
83_Q86_I1.1101.00
38_A310_N1.1051.00
189_F216_L1.1041.00
45_V75_L1.1031.00
182_L186_V1.0981.00
211_L215_A1.0931.00
142_G229_F1.0921.00
304_Y308_T1.0911.00
329_G333_G1.0901.00
114_R119_I1.0891.00
206_Y209_S1.0751.00
4_T8_I1.0741.00
137_V218_L1.0741.00
126_N129_L1.0741.00
159_I230_A1.0711.00
220_T224_V1.0701.00
178_L216_L1.0661.00
149_S159_I1.0631.00
7_M335_L1.0621.00
106_F309_L1.0591.00
118_S122_Y1.0561.00
209_S213_H1.0531.00
305_V309_L1.0481.00
256_A259_I1.0481.00
171_T290_T1.0381.00
318_I322_L1.0371.00
74_S77_A1.0351.00
119_I122_Y1.0341.00
27_I85_I1.0301.00
129_L214_M1.0291.00
96_L320_Y1.0261.00
11_V331_F1.0211.00
121_A125_P1.0161.00
182_L189_F1.0151.00
34_Q85_I1.0021.00
281_A326_L1.0021.00
175_G293_V1.0001.00
232_I275_Q0.9981.00
89_Y93_M0.9911.00
254_L259_I0.9871.00
332_L336_V0.9861.00
92_Q96_L0.9861.00
195_T213_H0.9811.00
118_S121_A0.9761.00
77_A83_Q0.9751.00
129_L133_T0.9751.00
145_I230_A0.9741.00
240_I264_V0.9731.00
215_A219_I0.9711.00
209_S212_Y0.9701.00
41_I45_V0.9651.00
6_Y338_G0.9631.00
101_F317_G0.9631.00
156_E238_T0.9571.00
101_F117_S0.9441.00
214_M218_L0.9421.00
175_G220_T0.9421.00
132_T136_I0.9421.00
95_N98_R0.9411.00
280_L329_G0.9321.00
105_Y313_P0.9311.00
135_T280_L0.9301.00
273_A333_G0.9291.00
150_A241_M0.9281.00
152_S157_K0.9281.00
94_Y97_M0.9231.00
196_S213_H0.9231.00
195_T206_Y0.9171.00
229_F279_A0.9161.00
131_F283_S0.9141.00
25_L319_T0.9111.00
142_G230_A0.9061.00
34_Q312_L0.9051.00
302_L306_A0.9041.00
134_A222_F0.9041.00
236_L268_G0.9041.00
292_V301_L0.8921.00
45_V67_A0.8911.00
123_Y302_L0.8901.00
41_I76_I0.8901.00
154_F157_K0.8901.00
151_K242_K0.8861.00
233_V237_V0.8851.00
250_K259_I0.8851.00
20_A24_I0.8831.00
120_I317_G0.8801.00
107_L114_R0.8771.00
70_K74_S0.8731.00
261_Y264_V0.8731.00
16_S19_L0.8701.00
142_G146_G0.8701.00
144_I147_L0.8691.00
174_L223_I0.8671.00
338_G344_I0.8611.00
335_L338_G0.8601.00
162_I166_H0.8501.00
120_I318_I0.8501.00
127_T131_F0.8491.00
64_I67_A0.8481.00
94_Y99_F0.8481.00
90_F93_M0.8471.00
70_K73_E0.8421.00
259_I264_V0.8391.00
147_L260_L0.8391.00
41_I75_L0.8381.00
27_I34_Q0.8381.00
328_L332_L0.8371.00
163_A230_A0.8371.00
132_T280_L0.8281.00
11_V15_F0.8231.00
144_I148_L0.8171.00
134_A221_I0.8161.00
208_I211_L0.8151.00
133_T296_W0.8141.00
146_G237_V0.8121.00
158_V162_I0.8111.00
337_Y344_I0.8101.00
268_G271_S0.8091.00
155_W158_V0.8091.00
160_A230_A0.8081.00
206_Y210_V0.8061.00
287_S290_T0.7971.00
249_A259_I0.7971.00
139_I144_I0.7961.00
17_V327_L0.7941.00
220_T290_T0.7941.00
207_G210_V0.7901.00
145_I226_V0.7891.00
258_R261_Y0.7891.00
125_P128_I0.7881.00
93_M97_M0.7881.00
194_M210_V0.7851.00
249_A254_L0.7831.00
103_T108_Q0.7811.00
171_T223_I0.7801.00
207_G211_L0.7781.00
219_I222_F0.7781.00
166_H223_I0.7771.00
256_A260_L0.7761.00
157_K160_A0.7741.00
41_I79_Y0.7661.00
210_V213_H0.7631.00
6_Y346_V0.7591.00
69_E72_R0.7571.00
23_T86_I0.7561.00
133_T214_M0.7531.00
273_A336_V0.7511.00
151_K238_T0.7501.00
179_I191_P0.7491.00
182_L188_V0.7471.00
67_A72_R0.7441.00
128_I132_T0.7381.00
10_K334_E0.7351.00
324_I328_L0.7341.00
143_T233_V0.7311.00
73_E82_N0.7281.00
134_A138_F0.7241.00
129_L132_T0.7231.00
233_V265_L0.7181.00
194_M214_M0.7171.00
15_F19_L0.7121.00
127_T287_S0.7111.00
245_F249_A0.7111.00
302_L318_I0.7101.00
93_M96_L0.7071.00
292_V305_V0.7061.00
130_L218_L0.7051.00
192_G295_E0.7021.00
124_L128_I0.7021.00
233_V236_L0.7011.00
212_Y215_A0.7011.00
292_V304_Y0.6981.00
147_L261_Y0.6921.00
141_A222_F0.6921.00
196_S210_V0.6921.00
312_L316_L0.6911.00
215_A218_L0.6901.00
288_L304_Y0.6901.00
182_L216_L0.6891.00
233_V268_G0.6881.00
316_L319_T0.6871.00
133_T211_L0.6821.00
180_A184_Y0.6821.00
138_F222_F0.6811.00
195_T210_V0.6801.00
281_A329_G0.6801.00
303_T322_L0.6781.00
185_A188_V0.6781.00
141_A145_I0.6771.00
221_I287_S0.6761.00
40_S312_L0.6751.00
190_P213_H0.6741.00
149_S156_E0.6731.00
305_V308_T0.6711.00
12_L15_F0.6691.00
195_T209_S0.6681.00
306_A315_I0.6671.00
133_T137_V0.6671.00
44_Q75_L0.6671.00
27_I35_E0.6661.00
133_T215_A0.6661.00
226_V230_A0.6611.00
76_I82_N0.6601.00
338_G345_K0.6591.00
123_Y301_L0.6581.00
342_P345_K0.6571.00
249_A252_R0.6571.00
34_Q316_L0.6531.00
159_I163_A0.6531.00
193_G213_H0.6531.00
120_I299_V0.6511.00
137_V219_I0.6501.00
326_L330_L0.6501.00
178_L219_I0.6491.00
119_I123_Y0.6471.00
297_P301_L0.6451.00
260_L264_V0.6431.00
6_Y10_K0.6411.00
269_S273_A0.6401.00
169_I173_W0.6391.00
333_G337_Y0.6361.00
325_V329_G0.6361.00
317_G321_V0.6351.00
171_T224_V0.6331.00
261_Y266_R0.6291.00
104_A107_L0.6261.00
22_L93_M0.6251.00
131_F280_L0.6251.00
229_F233_V0.6221.00
237_V268_G0.6201.00
131_F135_T0.6181.00
125_P129_L0.6151.00
107_L314_V0.6131.00
67_A71_Y0.6111.00
85_I88_K0.6111.00
277_I329_G0.6091.00
229_F275_Q0.6081.00
33_L315_I0.6081.00
315_I319_T0.6071.00
225_N228_G0.6061.00
270_P344_I0.6051.00
147_L265_L0.6041.00
143_T272_I0.6031.00
261_Y265_L0.6021.00
249_A263_H0.5961.00
314_V318_I0.5951.00
167_S227_G0.5941.00
20_A23_T0.5941.00
153_K157_K0.5931.00
255_P259_I0.5891.00
229_F276_A0.5881.00
327_L330_L0.5881.00
158_V161_I0.5861.00
323_T327_L0.5861.00
254_L263_H0.5851.00
173_W176_F0.5851.00
322_L326_L0.5841.00
41_I44_Q0.5831.00
121_A124_L0.5831.00
138_F229_F0.5811.00
236_L240_I0.5811.00
303_T306_A0.5791.00
71_Y75_L0.5781.00
229_F272_I0.5781.00
9_K13_I0.5761.00
129_L296_W0.5751.00
76_I81_L0.5751.00
281_A325_V0.5731.00
135_T139_I0.5721.00
156_E160_A0.5721.00
288_L303_T0.5701.00
222_F225_N0.5691.00
153_K156_E0.5681.00
131_F287_S0.5651.00
279_A282_G0.5651.00
153_K158_V0.5630.99
291_E298_G0.5630.99
161_I165_I0.5590.99
37_I310_N0.5580.99
87_D94_Y0.5550.99
288_L292_V0.5520.99
78_A108_Q0.5510.99
240_I267_S0.5470.99
117_S120_I0.5470.99
219_I223_I0.5450.99
243_E248_T0.5450.99
269_S272_I0.5400.99
281_A285_G0.5390.99
116_V314_V0.5390.99
273_A337_Y0.5370.99
228_G232_I0.5360.99
41_I67_A0.5350.99
68_V73_E0.5340.99
313_P316_L0.5320.99
99_F103_T0.5320.99
139_I229_F0.5310.99
269_S340_L0.5310.99
163_A227_G0.5310.99
307_I315_I0.5280.99
149_S234_R0.5270.99
171_T174_L0.5270.99
33_L36_V0.5260.99
108_Q115_E0.5260.99
183_A187_K0.5240.99
236_L272_I0.5230.99
194_M297_P0.5220.99
136_I140_V0.5190.99
211_L218_L0.5150.99
225_N279_A0.5140.99
228_G275_Q0.5140.99
130_L296_W0.5130.99
173_W293_V0.5130.99
26_Y89_Y0.5120.99
150_A156_E0.5110.99
103_T107_L0.5110.99
139_I143_T0.5110.99
164_V168_S0.5100.99
14_Y18_L0.5090.99
149_S160_A0.5090.99
41_I64_I0.5080.99
13_I17_V0.5080.99
23_T93_M0.5080.99
27_I86_I0.5080.99
138_F226_V0.5080.99
6_Y331_F0.5060.99
232_I236_L0.5060.99
299_V322_L0.5040.99
216_L220_T0.5040.99
336_V340_L0.5030.99
221_I290_T0.5020.99
7_M331_F0.5010.99
228_G279_A0.5010.99
227_G230_A0.5000.99
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tuiA 2 0.5948 99.9 0.709 Contact Map
4tquM 1 0.7787 99.8 0.733 Contact Map
3rlfF 1 0.7902 99.8 0.737 Contact Map
4ymuD 2 0.6006 99.8 0.739 Contact Map
2onkC 2 0.7098 99.8 0.74 Contact Map
3d31C 2 0.6839 99.8 0.747 Contact Map
4tquN 1 0.7414 99.7 0.764 Contact Map
3rlfG 1 0.7931 99.7 0.772 Contact Map
2p02A 2 0.2816 25.2 0.96 Contact Map
4odjA 2 0.2787 22.3 0.961 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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