GREMLIN Database
Q97YP7 - Oligo/dipeptide transport, ATP binding protein (DppF-1)
UniProt: Q97YP7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 325 (258)
Sequences: 56378 (34406)
Seq/√Len: 2142.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
50_E230_R3.8441.00
102_Y180_K3.2251.00
19_N41_G3.1481.00
16_K45_S3.0811.00
18_E79_N3.0191.00
37_K40_D2.7181.00
52_M232_I2.7151.00
22_V68_V2.6851.00
53_G228_S2.4541.00
47_K50_E2.4231.00
146_L210_K2.4181.00
230_R242_L2.4141.00
244_N247_E2.3751.00
79_N86_N2.3071.00
40_D238_K2.3051.00
23_Y37_K2.2591.00
83_K180_K2.2581.00
16_K81_Y2.2401.00
232_I239_I2.2351.00
153_L156_N2.2201.00
17_V20_L2.0991.00
21_K41_G2.0451.00
225_K246_N2.0251.00
48_E180_K2.0021.00
66_G217_I1.9941.00
21_K77_S1.9921.00
139_K178_N1.9541.00
139_K142_E1.8921.00
143_A176_V1.8841.00
18_E81_Y1.8561.00
243_G248_I1.8531.00
218_T224_A1.8051.00
24_F64_T1.7861.00
145_R151_L1.7401.00
92_N95_K1.7071.00
118_M122_D1.7041.00
141_E154_L1.6971.00
21_K37_K1.6761.00
66_G183_V1.6571.00
25_T35_V1.6531.00
86_N89_I1.6481.00
232_I242_L1.6451.00
13_Y47_K1.6261.00
13_Y16_K1.5831.00
125_A136_I1.5811.00
53_G224_A1.5781.00
243_G247_E1.5451.00
22_V73_Q1.5341.00
19_N43_T1.5331.00
121_Y155_E1.5321.00
22_V76_T1.5311.00
85_D95_K1.5211.00
24_F38_A1.5151.00
156_N160_Q1.5141.00
142_E146_L1.5131.00
23_Y76_T1.5101.00
125_A140_I1.5031.00
206_A212_F1.4951.00
137_D141_E1.4601.00
204_K226_I1.4551.00
141_E151_L1.4381.00
153_L161_L1.4351.00
17_V44_L1.4351.00
121_Y154_L1.4341.00
96_L100_S1.4321.00
20_L75_P1.4291.00
247_E251_N1.4051.00
279_K282_V1.3981.00
71_G96_L1.3871.00
178_N210_K1.3821.00
129_K136_I1.3811.00
23_Y35_V1.3761.00
184_A214_F1.3681.00
83_K102_Y1.3521.00
21_K40_D1.3301.00
124_L144_M1.3091.00
50_E229_D1.2881.00
121_Y125_A1.2881.00
17_V69_T1.2811.00
200_L223_I1.2521.00
119_R122_D1.2521.00
71_G74_K1.2411.00
46_I52_M1.2411.00
44_L232_I1.2321.00
51_I207_R1.2261.00
91_V95_K1.2231.00
106_I184_A1.2121.00
138_K142_E1.1951.00
44_L65_L1.1931.00
18_E45_S1.1901.00
161_L169_L1.1871.00
121_Y137_D1.1811.00
111_Y166_R1.1631.00
18_E43_T1.1551.00
51_I214_F1.1521.00
70_I105_M1.1521.00
52_M230_R1.1391.00
95_K98_D1.1361.00
13_Y45_S1.1231.00
144_M154_L1.1221.00
42_V65_L1.1191.00
204_K207_R1.1181.00
246_N250_K1.1131.00
52_M242_L1.1071.00
51_I228_S1.1061.00
277_E280_I1.0951.00
122_D125_A1.0941.00
203_I214_F1.0881.00
48_E83_K1.0851.00
121_Y140_I1.0841.00
137_D154_L1.0831.00
135_D138_K1.0831.00
123_V173_R1.0811.00
278_I281_K1.0761.00
54_V215_M1.0691.00
119_R155_E1.0691.00
152_E156_N1.0661.00
258_Q262_E1.0631.00
231_I245_S1.0591.00
68_V75_P1.0541.00
91_V96_L1.0271.00
141_E149_L1.0231.00
39_L68_V1.0201.00
255_P258_Q1.0191.00
142_E145_R1.0171.00
81_Y86_N1.0141.00
47_K230_R1.0111.00
99_I103_V1.0051.00
191_L199_I1.0051.00
178_N212_F1.0041.00
117_I159_Y1.0031.00
69_T215_M1.0001.00
19_N77_S0.9991.00
124_L176_V0.9991.00
277_E281_K0.9971.00
85_D91_V0.9971.00
150_P153_L0.9941.00
182_I212_F0.9861.00
104_Q179_P0.9751.00
148_D205_D0.9741.00
25_T34_Y0.9691.00
141_E145_R0.9641.00
134_S138_K0.9601.00
136_I140_I0.9591.00
65_L234_L0.9561.00
139_K143_A0.9561.00
125_A129_K0.9541.00
182_I214_F0.9471.00
275_I279_K0.9421.00
25_T33_K0.9411.00
247_E250_K0.9411.00
23_Y40_D0.9371.00
120_V161_L0.9361.00
14_V83_K0.9351.00
46_I181_Y0.9351.00
118_M126_T0.9341.00
48_E211_G0.9341.00
67_R72_L0.9291.00
207_R214_F0.9231.00
146_L205_D0.9201.00
278_I282_V0.9181.00
70_I183_V0.9181.00
277_E282_V0.9161.00
22_V64_T0.9111.00
119_R157_R0.9111.00
128_L176_V0.9091.00
125_A137_D0.9021.00
13_Y48_E0.8941.00
148_D198_E0.8901.00
145_R150_P0.8861.00
60_S234_L0.8851.00
54_V232_I0.8851.00
216_Y227_I0.8821.00
17_V80_V0.8811.00
255_P259_G0.8791.00
20_L68_V0.8791.00
47_K213_S0.8781.00
143_A172_A0.8701.00
245_S256_Y0.8681.00
137_D155_E0.8661.00
54_V65_L0.8621.00
143_A147_V0.8611.00
184_A203_I0.8531.00
114_I166_R0.8521.00
68_V80_V0.8521.00
196_K223_I0.8521.00
186_E219_H0.8511.00
67_R73_Q0.8471.00
276_K280_I0.8461.00
235_Y240_V0.8451.00
132_K139_K0.8441.00
196_K220_E0.8391.00
104_Q174_A0.8341.00
106_I171_I0.8321.00
207_R229_D0.8301.00
157_R160_Q0.8291.00
14_V82_I0.8241.00
93_K96_L0.8231.00
85_D102_Y0.8211.00
257_T261_I0.8181.00
143_A146_L0.8181.00
103_V181_Y0.8171.00
94_A98_D0.8141.00
15_V69_T0.8121.00
204_K227_I0.8111.00
51_I204_K0.8081.00
147_V172_A0.8051.00
223_I227_I0.7991.00
68_V73_Q0.7991.00
266_R269_P0.7931.00
274_K277_E0.7871.00
51_I227_I0.7871.00
82_I102_Y0.7861.00
202_I205_D0.7851.00
94_A97_K0.7831.00
201_K226_I0.7821.00
42_V239_I0.7761.00
131_K177_V0.7741.00
120_V169_L0.7711.00
254_H257_T0.7681.00
137_D140_I0.7681.00
240_V254_H0.7661.00
118_M123_V0.7641.00
135_D139_K0.7631.00
233_V252_P0.7631.00
181_Y215_M0.7631.00
46_I213_S0.7621.00
128_L132_K0.7611.00
39_L42_V0.7571.00
248_I257_T0.7551.00
133_M136_I0.7541.00
22_V39_L0.7521.00
38_A64_T0.7511.00
55_V224_A0.7511.00
235_Y259_G0.7481.00
161_L165_Q0.7461.00
216_Y228_S0.7461.00
19_N22_V0.7451.00
276_K279_K0.7441.00
41_G238_K0.7411.00
140_I154_L0.7401.00
245_S249_I0.7401.00
228_S231_I0.7361.00
183_V215_M0.7331.00
127_P173_R0.7271.00
235_Y238_K0.7261.00
228_S245_S0.7261.00
275_I278_I0.7261.00
158_V169_L0.7251.00
201_K205_D0.7201.00
91_V99_I0.7161.00
249_I252_P0.7151.00
153_L165_Q0.7131.00
106_I174_A0.7101.00
127_P177_V0.7081.00
143_A175_I0.7081.00
188_T223_I0.7051.00
98_D101_N0.7011.00
200_L226_I0.7011.00
115_D118_M0.7001.00
93_K98_D0.6941.00
201_K204_K0.6931.00
69_T80_V0.6901.00
233_V248_I0.6871.00
181_Y213_S0.6861.00
239_I242_L0.6851.00
101_N132_K0.6841.00
23_Y77_S0.6831.00
132_K178_N0.6821.00
252_P257_T0.6811.00
52_M215_M0.6811.00
46_I215_M0.6801.00
57_E235_Y0.6751.00
221_L249_I0.6731.00
82_I181_Y0.6711.00
149_L153_L0.6701.00
15_V82_I0.6701.00
17_V65_L0.6651.00
13_Y83_K0.6641.00
124_L140_I0.6591.00
24_F73_Q0.6591.00
55_V233_V0.6591.00
140_I143_A0.6581.00
41_G77_S0.6541.00
14_V48_E0.6511.00
68_V76_T0.6501.00
14_V181_Y0.6491.00
50_E242_L0.6491.00
259_G263_V0.6471.00
121_Y141_E0.6461.00
92_N96_L0.6441.00
138_K141_E0.6421.00
70_I103_V0.6411.00
63_T67_R0.6391.00
49_R213_S0.6381.00
51_I229_D0.6361.00
57_E256_Y0.6351.00
39_L65_L0.6301.00
114_I169_L0.6301.00
72_L107_Y0.6281.00
259_G262_E0.6281.00
15_V181_Y0.6271.00
138_K145_R0.6251.00
268_D271_L0.6241.00
241_E251_N0.6221.00
14_V47_K0.6221.00
171_I199_I0.6211.00
67_R105_M0.6201.00
197_G201_K0.6171.00
121_Y124_L0.6171.00
80_V89_I0.6121.00
241_E252_P0.6101.00
139_K146_L0.6081.00
264_Y267_I0.6061.00
163_G168_R0.6051.00
264_Y268_D0.6051.00
188_T199_I0.6021.00
243_G252_P0.6011.00
119_R123_V0.6011.00
82_I99_I0.5981.00
247_E253_L0.5961.00
109_D112_S0.5931.00
275_I280_I0.5931.00
151_L154_L0.5921.00
58_S186_E0.5901.00
23_Y38_A0.5851.00
175_I212_F0.5831.00
113_S170_S0.5831.00
144_M153_L0.5831.00
149_L165_Q0.5811.00
144_M149_L0.5801.00
123_V158_V0.5801.00
114_I123_V0.5781.00
37_K41_G0.5761.00
124_L127_P0.5751.00
57_E60_S0.5741.00
241_E248_I0.5711.00
48_E213_S0.5681.00
127_P130_Y0.5661.00
112_S166_R0.5641.00
66_G70_I0.5601.00
276_K282_V0.5601.00
224_A231_I0.5591.00
135_D149_L0.5581.00
270_S274_K0.5521.00
81_Y84_A0.5461.00
135_D142_E0.5461.00
156_N161_L0.5461.00
235_Y254_H0.5441.00
45_S242_L0.5411.00
14_V45_S0.5381.00
85_D98_D0.5361.00
108_Q163_G0.5331.00
262_E276_K0.5331.00
256_Y260_L0.5311.00
274_K278_I0.5301.00
207_R210_K0.5291.00
134_S137_D0.5291.00
152_E155_E0.5271.00
206_A210_K0.5271.00
162_S165_Q0.5261.00
96_L99_I0.5251.00
273_D277_E0.5251.00
120_V124_L0.5231.00
253_L258_Q0.5231.00
21_K76_T0.5221.00
128_L177_V0.5221.00
120_V144_M0.5221.00
14_V213_S0.5211.00
218_T223_I0.5201.00
243_G249_I0.5181.00
224_A228_S0.5171.00
126_T130_Y0.5171.00
19_N78_G0.5171.00
269_P272_R0.5171.00
180_K212_F0.5141.00
167_Q190_M0.5141.00
98_D102_Y0.5131.00
116_P159_Y0.5101.00
241_E253_L0.5091.00
225_K245_S0.5091.00
142_E178_N0.5051.00
125_A154_L0.5051.00
128_L136_I0.5011.00
252_P261_I0.5011.00
241_E257_T0.5011.00
89_I92_N0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4fwiB 1 0.9046 100 0.234 Contact Map
3tuiC 2 0.9108 100 0.259 Contact Map
4ry2A 2 0.7385 100 0.271 Contact Map
4ymuJ 2 0.7292 100 0.273 Contact Map
2yyzA 1 0.88 100 0.274 Contact Map
2oljA 2 0.7354 100 0.275 Contact Map
4u00A 1 0.7323 100 0.276 Contact Map
4mkiB 2 0.8738 100 0.276 Contact Map
1oxxK 1 0.92 100 0.276 Contact Map
4f4cA 1 0.72 100 0.277 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0125 seconds.