GREMLIN Database
Q97YP1 - Oligo/dipeptide transport, permease protein (DppB-2)
UniProt: Q97YP1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 333 (302)
Sequences: 20100 (12907)
Seq/√Len: 742.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
77_Q81_V3.3061.00
77_Q85_R3.2491.00
35_E82_Q3.1931.00
88_Y92_S2.8531.00
71_T76_N2.7281.00
84_I88_Y2.7211.00
63_Q67_N2.6901.00
224_M250_A2.6781.00
27_V83_F2.6171.00
237_R243_E2.4801.00
122_P204_W2.4281.00
115_Y282_I2.4201.00
245_T248_A2.4101.00
44_N70_T2.3191.00
134_V150_I2.2421.00
233_V250_A2.2301.00
28_I83_F2.2121.00
227_V232_F2.2091.00
287_Y291_I2.1391.00
80_Y84_I2.1361.00
263_G319_M2.0671.00
227_V230_S2.0521.00
108_E288_L2.0521.00
242_K245_T2.0291.00
104_Y107_N2.0291.00
244_S247_R2.0121.00
62_F65_I1.9471.00
66_I70_T1.9391.00
10_N14_K1.9351.00
228_L250_A1.9191.00
129_L133_V1.9001.00
147_D221_R1.8941.00
65_I68_D1.8931.00
126_F209_F1.8421.00
180_I198_K1.8141.00
101_H108_E1.8111.00
68_D72_L1.7931.00
174_A182_I1.7771.00
81_V85_R1.7761.00
26_L309_T1.7721.00
241_L245_T1.7671.00
141_K144_K1.7401.00
180_I201_W1.7301.00
233_V246_V1.7271.00
23_L310_L1.7241.00
259_I326_V1.6951.00
103_E107_N1.6931.00
67_N70_T1.6911.00
145_A149_I1.6881.00
105_V303_G1.6781.00
137_Y141_K1.6761.00
139_A224_M1.6641.00
141_K146_V1.6621.00
67_N71_T1.6411.00
89_A94_N1.6391.00
106_I110_L1.6351.00
235_Y239_S1.5871.00
171_V176_Y1.5821.00
146_V150_I1.5711.00
137_Y146_V1.5591.00
136_A224_M1.5591.00
185_I282_I1.5541.00
44_N47_I1.5491.00
322_I325_L1.5491.00
130_L133_V1.5451.00
8_F12_A1.5361.00
85_R88_Y1.5091.00
204_W209_F1.4971.00
130_L213_F1.4961.00
231_D234_K1.4961.00
289_G304_S1.4931.00
17_V21_I1.4721.00
260_T323_Y1.4641.00
227_V254_S1.4531.00
127_Q212_G1.4471.00
227_V233_V1.4291.00
103_E111_Q1.4161.00
232_F253_N1.4001.00
19_R313_L1.3921.00
90_L95_L1.3891.00
172_V176_Y1.3881.00
24_L83_F1.3751.00
164_F168_V1.3711.00
85_R89_A1.3641.00
128_T262_T1.3591.00
115_Y185_I1.3591.00
95_L303_G1.3421.00
292_A300_L1.3401.00
118_I185_I1.3331.00
169_L207_Q1.3321.00
227_V250_A1.3181.00
143_N147_D1.3161.00
81_V84_I1.3131.00
69_I72_L1.3021.00
69_I73_Y1.3021.00
131_A220_M1.3001.00
111_Q114_P1.2981.00
24_L28_I1.2911.00
118_I122_P1.2891.00
95_L106_I1.2881.00
131_A216_R1.2811.00
74_G77_Q1.2801.00
239_S249_I1.2781.00
115_Y118_I1.2691.00
209_F213_F1.2691.00
108_E300_L1.2651.00
216_R265_D1.2571.00
77_Q80_Y1.2561.00
46_A66_I1.2551.00
27_V86_Y1.2471.00
135_G139_A1.2451.00
78_P81_V1.2431.00
221_R225_V1.2411.00
124_F262_T1.2291.00
9_L12_A1.2291.00
13_I17_V1.2251.00
140_L243_E1.2241.00
103_E108_E1.2171.00
157_Q214_P1.2091.00
97_Y104_Y1.2001.00
141_K243_E1.1981.00
288_L300_L1.1851.00
219_L261_R1.1771.00
91_F94_N1.1761.00
160_I165_I1.1731.00
135_G220_M1.1631.00
172_V177_I1.1621.00
150_I217_G1.1571.00
304_S308_L1.1551.00
220_M258_V1.1501.00
47_I66_I1.1341.00
256_I323_Y1.1301.00
118_I200_Y1.1201.00
138_A150_I1.1191.00
139_A228_L1.1141.00
28_I32_F1.0941.00
154_M217_G1.0731.00
145_A148_H1.0701.00
74_G85_R1.0671.00
321_L325_L1.0641.00
107_N111_Q1.0611.00
290_I294_T1.0591.00
267_A312_A1.0581.00
315_V319_M1.0561.00
89_A92_S1.0481.00
24_L87_L1.0441.00
162_G276_I1.0401.00
220_M224_M1.0351.00
201_W205_I1.0341.00
134_V217_G1.0331.00
23_L313_L1.0311.00
139_A225_V1.0271.00
110_L114_P1.0261.00
207_Q211_F1.0211.00
173_F177_I1.0201.00
168_V172_V1.0201.00
27_V306_F1.0131.00
100_Q295_E1.0101.00
236_A241_L1.0021.00
16_A20_I1.0011.00
186_Q199_V1.0001.00
19_R317_Y0.9971.00
123_P209_F0.9891.00
98_D297_N0.9811.00
166_L207_Q0.9811.00
108_E111_Q0.9771.00
68_D71_T0.9741.00
224_M254_S0.9731.00
31_W113_L0.9731.00
169_L202_L0.9711.00
71_T77_Q0.9671.00
9_L13_I0.9641.00
126_F204_W0.9641.00
243_E246_V0.9601.00
12_A321_L0.9591.00
180_I202_L0.9561.00
236_A246_V0.9551.00
197_L201_W0.9521.00
98_D103_E0.9521.00
323_Y327_D0.9461.00
293_A296_L0.9451.00
153_Y157_Q0.9451.00
28_I79_L0.9401.00
133_V136_A0.9381.00
35_E79_L0.9341.00
254_S257_P0.9341.00
64_N68_D0.9301.00
291_I295_E0.9241.00
107_N110_L0.9191.00
241_L246_V0.9191.00
97_Y102_H0.9181.00
16_A317_Y0.9181.00
266_L315_V0.9151.00
200_Y204_W0.9141.00
298_I302_T0.9131.00
50_A69_I0.9131.00
318_A322_I0.9121.00
147_D225_V0.9091.00
120_T269_I0.9071.00
288_L292_A0.9061.00
142_R229_D0.9031.00
39_E296_L0.9031.00
151_S217_G0.9031.00
25_G29_L0.9031.00
32_F79_L0.9021.00
173_F180_I0.8961.00
237_R246_V0.8961.00
11_Y324_P0.8951.00
259_I319_M0.8861.00
17_V321_L0.8831.00
90_L306_F0.8831.00
112_Y288_L0.8791.00
289_G292_A0.8791.00
143_N148_H0.8781.00
136_A251_R0.8671.00
149_I153_Y0.8641.00
64_N67_N0.8611.00
109_V303_G0.8601.00
131_A135_G0.8541.00
99_F299_P0.8531.00
278_Y287_Y0.8491.00
32_F35_E0.8471.00
324_P330_I0.8441.00
314_V318_A0.8421.00
88_Y91_F0.8311.00
246_V250_A0.8301.00
116_T120_T0.8281.00
236_A249_I0.8281.00
132_I220_M0.8261.00
83_F87_L0.8241.00
166_L279_I0.8221.00
50_A61_Y0.8211.00
123_P208_V0.8201.00
140_L247_R0.8201.00
124_F266_L0.8181.00
63_Q66_I0.8121.00
247_R250_A0.8101.00
134_V213_F0.8101.00
118_I121_L0.8061.00
121_L125_I0.8041.00
148_H151_S0.8041.00
46_A50_A0.8031.00
84_I87_L0.7971.00
205_I209_F0.7961.00
226_D230_S0.7961.00
128_T133_V0.7931.00
223_T254_S0.7881.00
123_P127_Q0.7841.00
146_V149_I0.7831.00
267_A315_V0.7811.00
122_P282_I0.7811.00
21_I24_L0.7781.00
44_N50_A0.7771.00
87_L91_F0.7771.00
213_F217_G0.7751.00
131_A217_G0.7741.00
158_Y214_P0.7711.00
35_E298_I0.7691.00
86_Y90_L0.7671.00
135_G224_M0.7651.00
323_Y330_I0.7621.00
29_L33_V0.7611.00
45_P48_W0.7581.00
223_T227_V0.7581.00
220_M254_S0.7581.00
165_I210_I0.7551.00
212_G215_V0.7551.00
142_R225_V0.7551.00
87_L90_L0.7541.00
273_I276_I0.7501.00
109_V304_S0.7491.00
133_V137_Y0.7481.00
119_L204_W0.7481.00
46_A69_I0.7461.00
61_Y66_I0.7431.00
185_I200_Y0.7361.00
310_L314_V0.7361.00
132_I258_V0.7361.00
28_I80_Y0.7341.00
173_F202_L0.7341.00
303_G307_F0.7311.00
201_W204_W0.7291.00
121_L266_L0.7271.00
30_L305_F0.7261.00
173_F179_A0.7251.00
236_A239_S0.7221.00
321_L324_P0.7221.00
117_I121_L0.7161.00
223_T226_D0.7111.00
150_I154_M0.7101.00
105_V300_L0.7081.00
127_Q209_F0.7081.00
162_G210_I0.7071.00
130_L134_V0.7011.00
220_M223_T0.7011.00
170_W182_I0.7011.00
114_P118_I0.7001.00
88_Y93_F0.6981.00
114_P117_I0.6971.00
31_W35_E0.6971.00
49_Y69_I0.6961.00
61_Y65_I0.6881.00
207_Q276_I0.6881.00
105_V288_L0.6841.00
302_T305_F0.6841.00
278_Y290_I0.6731.00
130_L209_F0.6661.00
176_Y179_A0.6641.00
17_V20_I0.6611.00
312_A316_L0.6581.00
110_L113_L0.6541.00
20_I24_L0.6531.00
292_A301_L0.6531.00
324_P331_K0.6521.00
214_P217_G0.6481.00
15_R18_D0.6461.00
108_E112_Y0.6451.00
291_I294_T0.6431.00
23_L27_V0.6421.00
149_I152_N0.6421.00
288_L304_S0.6421.00
259_I322_I0.6411.00
138_A147_D0.6401.00
113_L117_I0.6401.00
162_G166_L0.6371.00
308_L312_A0.6351.00
183_S281_G0.6331.00
234_K237_R0.6321.00
46_A70_T0.6311.00
162_G165_I0.6311.00
184_G199_V0.6281.00
154_M214_P0.6281.00
157_Q210_I0.6271.00
283_P287_Y0.6251.00
38_P107_N0.6251.00
20_I314_V0.6241.00
181_P184_G0.6231.00
70_T76_N0.6221.00
171_V175_V0.6171.00
57_K61_Y0.6151.00
123_P273_I0.6121.00
216_R261_R0.6111.00
128_T216_R0.6101.00
112_Y287_Y0.6101.00
289_G308_L0.6061.00
202_L207_Q0.6051.00
241_L249_I0.6051.00
129_L132_I0.6041.00
301_L305_F0.6041.00
70_T75_F0.6041.00
46_A49_Y0.6041.00
93_F97_Y0.6021.00
21_I25_G0.6021.00
181_P199_V0.6021.00
98_D101_H0.5981.00
147_D151_S0.5971.00
26_L30_L0.5971.00
57_K60_S0.5951.00
32_F36_A0.5931.00
215_V261_R0.5921.00
152_N156_L0.5911.00
27_V87_L0.5891.00
152_N155_I0.5881.00
67_N76_N0.5871.00
122_P201_W0.5871.00
278_Y291_I0.5871.00
79_L82_Q0.5861.00
22_L313_L0.5841.00
148_H152_N0.5841.00
255_I259_I0.5831.00
122_P126_F0.5821.00
44_N49_Y0.5821.00
56_G61_Y0.5821.00
11_Y317_Y0.5801.00
116_T277_E0.5781.00
65_I69_I0.5781.00
169_L205_I0.5781.00
216_R258_V0.5771.00
35_E302_T0.5761.00
44_N48_W0.5751.00
45_P49_Y0.5751.00
232_F236_A0.5751.00
216_R220_M0.5741.00
261_R265_D0.5731.00
198_K202_L0.5721.00
181_P198_K0.5691.00
14_K17_V0.5691.00
220_M251_R0.5681.00
180_I184_G0.5671.00
263_G315_V0.5651.00
199_V202_L0.5641.00
319_M323_Y0.5631.00
219_L223_T0.5621.00
234_K238_L0.5621.00
288_L291_I0.5621.00
162_G211_F0.5611.00
164_F167_A0.5601.00
174_A198_K0.5591.00
209_F212_G0.5551.00
133_V247_R0.5551.00
125_I129_L0.5541.00
120_T273_I0.5521.00
265_D268_F0.5521.00
274_Y278_Y0.5481.00
302_T306_F0.5471.00
274_Y290_I0.5471.00
128_T132_I0.5461.00
81_V88_Y0.5461.00
205_I210_I0.5441.00
138_A151_S0.5431.00
215_V265_D0.5431.00
141_K147_D0.5411.00
18_D21_I0.5391.00
118_I282_I0.5381.00
34_V301_L0.5381.00
46_A73_Y0.5381.00
256_I330_I0.5371.00
215_V219_L0.5371.00
100_Q291_I0.5371.00
95_L109_V0.5341.00
255_I258_V0.5341.00
136_A247_R0.5341.00
198_K201_W0.5331.00
19_R22_L0.5331.00
211_F214_P0.5301.00
311_Y315_V0.5301.00
119_L277_E0.5301.00
247_R252_R0.5281.00
144_K147_D0.5261.00
122_P125_I0.5251.00
317_Y321_L0.5241.00
242_K246_V0.5201.00
177_I180_I0.5201.00
144_K149_I0.5191.00
160_I164_F0.5191.00
124_F128_T0.5191.00
233_V237_R0.5181.00
18_D22_L0.5181.00
72_L102_H0.5171.00
90_L93_F0.5151.00
136_A140_L0.5151.00
122_P197_L0.5141.00
164_F207_Q0.5141.00
116_T273_I0.5131.00
126_F205_I0.5131.00
300_L304_S0.5121.00
309_T313_L0.5121.00
224_M228_L0.5091.00
50_A56_G0.5081.00
101_H300_L0.5071.00
230_S234_K0.5021.00
62_F67_N0.5001.00
247_R251_R0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3tuiA 2 0.6246 99.9 0.686 Contact Map
4tquM 1 0.8078 99.8 0.696 Contact Map
2onkC 2 0.7447 99.8 0.712 Contact Map
3rlfF 1 0.8258 99.8 0.714 Contact Map
3d31C 2 0.7387 99.8 0.715 Contact Map
4ymuD 2 0.6276 99.8 0.721 Contact Map
4tquN 1 0.7778 99.7 0.734 Contact Map
3rlfG 1 0.8228 99.6 0.754 Contact Map
3j9tb 1 0 5 0.967 Contact Map
2yevC 1 0.0871 4.8 0.967 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0095 seconds.