GREMLIN Database
Q97YM4 - N-acetylglucosaminyltransferase related protein (NodC-like)
UniProt: Q97YM4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 422 (368)
Sequences: 9856 (7555)
Seq/√Len: 393.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
74_N103_E4.9251.00
88_N155_N4.7141.00
217_R221_L4.2671.00
65_S137_G3.5531.00
139_I158_V3.5431.00
141_V214_A3.1371.00
139_I161_F2.9751.00
222_E252_N2.9221.00
67_I96_V2.9121.00
103_E106_D2.8791.00
219_Y254_Y2.8411.00
105_V109_K2.8161.00
156_E261_T2.7391.00
96_V131_G2.6891.00
271_T274_K2.6401.00
79_E110_K2.6321.00
199_R202_N2.6201.00
92_E137_G2.5761.00
65_S92_E2.5721.00
64_V158_V2.5671.00
160_P259_Q2.5451.00
106_D110_K2.5101.00
166_V257_V2.3981.00
152_N156_E2.3971.00
68_V85_V2.3511.00
161_F214_A2.2851.00
139_I214_A2.2481.00
181_R184_Y2.2241.00
165_K255_K2.2141.00
64_V154_I2.2011.00
63_K136_I2.1501.00
317_P320_F2.1491.00
92_E114_K2.1461.00
157_I214_A2.1111.00
108_S111_Y2.1041.00
218_S222_E2.1011.00
163_D255_K2.0361.00
63_K137_G2.0181.00
167_A254_Y2.0111.00
63_K138_D2.0011.00
317_P321_A1.9681.00
303_P307_R1.9671.00
141_V154_I1.9561.00
208_I213_A1.9401.00
79_E83_R1.9381.00
313_Y317_P1.9171.00
97_H117_S1.9101.00
222_E254_Y1.9021.00
65_S94_I1.8951.00
65_S135_A1.8871.00
39_R43_L1.8691.00
97_H100_K1.8481.00
88_N152_N1.7811.00
278_Q282_W1.7751.00
392_I395_L1.7481.00
219_Y249_A1.7071.00
88_N151_D1.7051.00
107_I111_Y1.6931.00
168_G256_T1.6681.00
107_I110_K1.6651.00
191_E194_R1.6471.00
61_K90_P1.6391.00
132_W140_I1.6301.00
244_A248_Y1.6001.00
62_V158_V1.5981.00
306_Y310_M1.5961.00
108_S115_V1.5591.00
391_G395_L1.5501.00
104_V108_S1.5371.00
39_R42_L1.5331.00
190_I194_R1.5191.00
135_A217_R1.5011.00
106_D109_K1.4991.00
303_P306_Y1.4891.00
313_Y316_A1.4831.00
63_K92_E1.4571.00
306_Y309_H1.4551.00
302_M306_Y1.4461.00
139_I216_R1.4461.00
72_G100_K1.4061.00
370_S373_I1.4061.00
170_Q173_P1.4041.00
191_E195_D1.4031.00
388_I392_I1.3861.00
89_K158_V1.3811.00
190_I193_S1.3741.00
354_Y357_L1.3671.00
84_S149_M1.3651.00
95_V108_S1.3631.00
92_E136_I1.3551.00
377_K381_K1.3461.00
368_K372_G1.3361.00
103_E107_I1.3311.00
83_R111_Y1.3271.00
124_K128_L1.3191.00
79_E107_I1.3091.00
96_V127_A1.2941.00
131_G135_A1.2921.00
87_K154_I1.2761.00
29_P32_F1.2721.00
46_F50_Y1.2711.00
140_I220_L1.2691.00
156_E159_K1.2681.00
149_M153_T1.2671.00
36_F40_Q1.2651.00
62_V89_K1.2581.00
32_F36_F1.2561.00
35_F43_L1.2531.00
73_E145_S1.2451.00
36_F39_R1.2441.00
140_I217_R1.2421.00
35_F39_R1.2381.00
354_Y358_I1.2231.00
327_T330_V1.2221.00
147_T264_A1.2141.00
105_V108_S1.2131.00
31_N35_F1.2121.00
378_L381_K1.2061.00
398_I401_M1.2041.00
34_I38_F1.1981.00
321_A324_L1.1921.00
32_F39_R1.1891.00
336_A339_W1.1861.00
70_E78_F1.1851.00
358_I361_F1.1811.00
278_Q281_R1.1781.00
316_A320_F1.1771.00
66_A141_V1.1771.00
167_A216_R1.1741.00
357_L361_F1.1701.00
312_T316_A1.1701.00
97_H105_V1.1681.00
395_L399_F1.1631.00
285_S288_L1.1611.00
130_I134_N1.1601.00
175_L268_A1.1581.00
379_P383_S1.1571.00
143_L149_M1.1571.00
240_A285_S1.1571.00
350_P354_Y1.1561.00
29_P33_A1.1481.00
379_P382_I1.1441.00
84_S148_I1.1421.00
70_E104_V1.1401.00
177_R184_Y1.1331.00
350_P353_L1.1271.00
387_L390_L1.1211.00
82_L111_Y1.1191.00
81_C85_V1.1121.00
169_V259_Q1.1081.00
396_F400_P1.1071.00
365_L369_I1.1001.00
367_M371_F1.0981.00
294_M297_G1.0971.00
378_L382_I1.0901.00
80_K83_R1.0841.00
394_G397_V1.0831.00
313_Y320_F1.0831.00
326_D330_V1.0801.00
66_A87_K1.0791.00
306_Y312_T1.0771.00
168_G249_A1.0751.00
109_K117_S1.0751.00
384_F388_I1.0711.00
38_F41_F1.0681.00
129_I133_L1.0671.00
320_F323_A1.0651.00
266_S269_Q1.0651.00
153_T212_I1.0591.00
386_D390_L1.0541.00
25_F36_F1.0501.00
85_V93_I1.0481.00
293_E296_S1.0461.00
61_K155_N1.0421.00
365_L370_S1.0411.00
29_P36_F1.0391.00
65_S217_R1.0341.00
128_L142_Q1.0241.00
300_F303_P1.0241.00
397_V401_M1.0221.00
23_G27_Y1.0181.00
309_H313_Y1.0161.00
192_Y195_D1.0141.00
302_M307_R1.0031.00
401_M404_Y1.0031.00
40_Q43_L1.0021.00
130_I133_L0.9991.00
67_I131_G0.9961.00
386_D395_L0.9961.00
305_K309_H0.9911.00
58_S61_K0.9871.00
36_F43_L0.9871.00
313_Y319_S0.9841.00
241_D285_S0.9841.00
309_H312_T0.9841.00
395_L398_I0.9781.00
157_I171_G0.9771.00
115_V118_L0.9771.00
368_K371_F0.9761.00
190_I279_Q0.9741.00
386_D389_T0.9731.00
300_F307_R0.9721.00
216_R254_Y0.9721.00
138_D218_S0.9641.00
32_F42_L0.9631.00
299_F303_P0.9631.00
173_P211_K0.9621.00
29_P43_L0.9621.00
323_A327_T0.9551.00
170_Q175_L0.9531.00
167_A249_A0.9531.00
353_L356_L0.9521.00
357_L360_I0.9491.00
314_L317_P0.9481.00
316_A319_S0.9471.00
132_W135_A0.9461.00
187_G190_I0.9451.00
160_P257_V0.9431.00
304_G308_F0.9411.00
228_N236_K0.9391.00
394_G398_I0.9371.00
383_S390_L0.9341.00
285_S289_Y0.9331.00
40_Q44_R0.9251.00
72_G101_R0.9151.00
116_I130_I0.9111.00
380_D383_S0.9081.00
78_F82_L0.9071.00
30_V34_I0.9061.00
102_K106_D0.9031.00
137_G217_R0.9031.00
279_Q282_W0.9021.00
154_I214_A0.9001.00
33_A37_L0.8991.00
25_F29_P0.8951.00
355_S358_I0.8941.00
28_F32_F0.8941.00
395_L402_F0.8901.00
85_V149_M0.8891.00
356_L360_I0.8871.00
161_F166_V0.8841.00
293_E297_G0.8841.00
366_S369_I0.8801.00
78_F95_V0.8751.00
223_T226_H0.8721.00
57_L60_D0.8701.00
33_A36_F0.8671.00
46_F49_S0.8671.00
369_I373_I0.8621.00
398_I402_F0.8601.00
32_F44_R0.8561.00
195_D198_V0.8551.00
377_K380_D0.8491.00
81_C86_A0.8451.00
275_F279_Q0.8421.00
168_G208_I0.8411.00
98_D121_R0.8371.00
29_P35_F0.8321.00
150_E265_K0.8311.00
395_L401_M0.8281.00
238_I244_A0.8271.00
307_R311_L0.8271.00
377_K382_I0.8271.00
119_S123_G0.8261.00
307_R317_P0.8241.00
361_F364_Y0.8221.00
391_G398_I0.8211.00
27_Y31_N0.8201.00
100_K104_V0.8151.00
394_G402_F0.8141.00
366_S371_F0.8091.00
198_V202_N0.8091.00
343_A347_F0.8071.00
365_L372_G0.8061.00
182_I185_L0.8031.00
32_F35_F0.8011.00
157_I169_V0.7941.00
299_F302_M0.7941.00
366_S370_S0.7941.00
92_E135_A0.7941.00
85_V143_L0.7921.00
365_L368_K0.7901.00
193_S196_I0.7851.00
152_N155_N0.7851.00
47_S50_Y0.7841.00
367_M373_I0.7821.00
36_F42_L0.7811.00
171_G212_I0.7781.00
183_P187_G0.7771.00
400_P403_I0.7751.00
249_A254_Y0.7721.00
25_F32_F0.7691.00
81_C84_S0.7671.00
34_I42_L0.7621.00
349_I353_L0.7601.00
390_L394_G0.7601.00
97_H118_L0.7591.00
26_I29_P0.7581.00
275_F278_Q0.7581.00
352_I356_L0.7571.00
22_Y28_F0.7571.00
147_T266_S0.7541.00
317_P326_D0.7521.00
74_N107_I0.7491.00
400_P404_Y0.7471.00
36_F44_R0.7471.00
347_F350_P0.7461.00
37_L41_F0.7411.00
250_N256_T0.7391.00
344_Y352_I0.7371.00
356_L359_F0.7351.00
353_L357_L0.7351.00
307_R310_M0.7311.00
98_D118_L0.7301.00
125_R129_I0.7291.00
387_L391_G0.7291.00
352_I359_F0.7281.00
324_L327_T0.7281.00
157_I212_I0.7231.00
337_L340_S0.7211.00
148_I176_F0.7211.00
71_Y121_R0.7191.00
212_I264_A0.7181.00
336_A340_S0.7181.00
393_L396_F0.7161.00
349_I360_I0.7161.00
378_L383_S0.7151.00
70_E145_S0.7131.00
62_V162_A0.7121.00
364_Y367_M0.7111.00
397_V400_P0.7111.00
345_Y349_I0.7091.00
303_P309_H0.7081.00
211_K266_S0.7081.00
120_R123_G0.7071.00
22_Y25_F0.7061.00
181_R185_L0.7031.00
273_L277_N0.6991.00
95_V98_D0.6981.00
384_F387_L0.6971.00
251_M296_S0.6971.00
191_E196_I0.6971.00
345_Y354_Y0.6961.00
239_A285_S0.6961.00
240_A243_K0.6961.00
215_Y249_A0.6951.00
248_Y251_M0.6931.00
104_V107_I0.6911.00
125_R241_D0.6901.00
324_L330_V0.6890.99
184_Y188_Q0.6850.99
47_S51_K0.6840.99
366_S372_G0.6830.99
33_A43_L0.6830.99
351_I358_I0.6820.99
118_L130_I0.6820.99
363_L369_I0.6820.99
129_I132_W0.6810.99
223_T248_Y0.6790.99
317_P324_L0.6770.99
167_A219_Y0.6710.99
364_Y368_K0.6700.99
320_F327_T0.6680.99
349_I356_L0.6670.99
369_I372_G0.6670.99
170_Q208_I0.6660.99
301_K304_G0.6650.99
396_F399_F0.6640.99
383_S386_D0.6640.99
317_P322_L0.6630.99
224_I227_F0.6630.99
320_F329_L0.6620.99
49_S53_Y0.6610.99
141_V157_I0.6600.99
307_R313_Y0.6590.99
87_K153_T0.6580.99
246_T256_T0.6550.99
348_N355_S0.6510.99
363_L366_S0.6510.99
221_L224_I0.6510.99
395_L400_P0.6510.99
82_L95_V0.6500.99
352_I355_S0.6500.99
392_I396_F0.6500.99
68_V143_L0.6480.99
119_S122_V0.6470.99
122_V126_G0.6450.99
381_K388_I0.6440.99
367_M370_S0.6420.99
328_L332_G0.6410.99
345_Y348_N0.6410.99
35_F42_L0.6410.99
190_I197_V0.6400.99
393_L397_V0.6370.99
190_I195_D0.6350.99
35_F38_F0.6350.99
387_L395_L0.6340.99
34_I39_R0.6330.99
66_A154_I0.6320.99
317_P330_V0.6300.99
31_N34_I0.6250.99
35_F40_Q0.6240.99
166_V255_K0.6240.99
30_V37_L0.6230.99
125_R128_L0.6220.99
22_Y26_I0.6200.99
351_I354_Y0.6190.99
132_W220_L0.6180.99
399_F402_F0.6180.99
377_K383_S0.6180.99
46_F53_Y0.6160.99
388_I391_G0.6150.99
373_I377_K0.6140.99
380_D390_L0.6140.99
105_V117_S0.6140.99
80_K148_I0.6120.99
141_V153_T0.6110.99
45_H49_S0.6110.99
100_K105_V0.6110.99
309_H317_P0.6110.99
306_Y317_P0.6100.99
128_L227_F0.6100.99
320_F324_L0.6090.99
301_K306_Y0.6080.99
94_I114_K0.6070.99
372_G377_K0.6070.99
74_N104_V0.6060.99
304_G309_H0.6050.99
343_A346_G0.6040.99
269_Q278_Q0.6020.99
316_A327_T0.6000.99
316_A321_A0.6000.99
94_I131_G0.5990.99
391_G397_V0.5940.99
160_P169_V0.5930.98
385_V389_T0.5920.98
313_Y318_F0.5920.98
306_Y313_Y0.5910.98
223_T249_A0.5900.98
314_L318_F0.5900.98
368_K373_I0.5880.98
49_S54_I0.5870.98
351_I357_L0.5870.98
84_S87_K0.5850.98
150_E263_V0.5830.98
29_P40_Q0.5820.98
166_V169_V0.5810.98
70_E95_V0.5810.98
37_L40_Q0.5800.98
87_K149_M0.5790.98
317_P325_I0.5790.98
22_Y32_F0.5790.98
67_I132_W0.5780.98
132_W142_Q0.5780.98
311_L316_A0.5770.98
38_F42_L0.5760.98
363_L372_G0.5760.98
384_F391_G0.5750.98
382_I386_D0.5750.98
68_V95_V0.5750.98
342_L347_F0.5740.98
394_G401_M0.5740.98
68_V81_C0.5720.98
94_I135_A0.5710.98
198_V201_L0.5710.98
187_G191_E0.5700.98
397_V402_F0.5690.98
351_I355_S0.5680.98
171_G175_L0.5680.98
319_S323_A0.5670.98
63_K91_D0.5650.98
390_L402_F0.5650.98
325_I329_L0.5630.98
363_L367_M0.5630.98
32_F41_F0.5600.98
389_T396_F0.5590.98
399_F404_Y0.5590.98
346_G357_L0.5590.98
127_A131_G0.5540.98
47_S52_P0.5530.98
317_P323_A0.5490.98
241_D244_A0.5490.98
389_T392_I0.5480.97
282_W285_S0.5460.97
94_I97_H0.5460.97
372_G379_P0.5460.97
381_K384_F0.5450.97
306_Y311_L0.5440.97
355_S359_F0.5430.97
322_L330_V0.5430.97
241_D289_Y0.5410.97
143_L212_I0.5410.97
386_D391_G0.5400.97
147_T211_K0.5400.97
32_F40_Q0.5380.97
326_D331_P0.5370.97
28_F35_F0.5370.97
392_I400_P0.5370.97
304_G307_R0.5360.97
23_G29_P0.5360.97
172_R258_Y0.5340.97
305_K313_Y0.5340.97
24_V28_F0.5330.97
33_A39_R0.5300.97
312_T317_P0.5290.97
67_I135_A0.5290.97
347_F352_I0.5270.97
393_L400_P0.5270.97
399_F403_I0.5270.97
389_T395_L0.5260.97
357_L365_L0.5250.97
71_Y101_R0.5250.97
49_S52_P0.5250.97
316_A330_V0.5240.97
265_K269_Q0.5230.97
176_F267_A0.5230.97
26_I39_R0.5220.97
142_Q208_I0.5220.97
346_G350_P0.5210.97
251_M293_E0.5200.97
207_V243_K0.5190.97
62_V138_D0.5190.97
349_I361_F0.5180.96
81_C143_L0.5180.96
70_E81_C0.5170.96
393_L402_F0.5170.96
354_Y359_F0.5160.96
362_G367_M0.5150.96
351_I356_L0.5140.96
367_M372_G0.5130.96
22_Y33_A0.5130.96
362_G366_S0.5110.96
70_E73_E0.5110.96
24_V32_F0.5100.96
32_F37_L0.5100.96
305_K312_T0.5090.96
361_F365_L0.5080.96
345_Y350_P0.5080.96
61_K89_K0.5080.96
284_R288_L0.5070.96
352_I357_L0.5070.96
363_L373_I0.5070.96
124_K144_D0.5060.96
65_S136_I0.5050.96
346_G349_I0.5050.96
30_V36_F0.5050.96
348_N353_L0.5040.96
243_K247_Y0.5040.96
318_F326_D0.5030.96
184_Y187_G0.5010.96
362_G373_I0.5010.96
309_H316_A0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4p02A 1 0.9455 100 0.391 Contact Map
2z86A 2 0.6825 100 0.58 Contact Map
1qg8A 1 0.5071 100 0.603 Contact Map
1xhbA 1 0.8531 100 0.604 Contact Map
3bcvA 2 0.4147 100 0.613 Contact Map
2d7iA 1 0.8839 100 0.627 Contact Map
2bo4A 4 0.7938 100 0.63 Contact Map
5ajoA 1 0.8412 100 0.638 Contact Map
3ckjA 2 0.6374 100 0.64 Contact Map
3l7iA 4 0.1232 100 0.642 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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