GREMLIN Database
Q97YL1 - Ring oxydation complex/ phenylacetic acid degradation related protein
UniProt: Q97YL1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 261 (211)
Sequences: 1358 (699)
Seq/√Len: 48.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
104_K107_A4.0631.00
194_Q198_N4.0551.00
52_G93_I3.7101.00
50_V211_S3.4591.00
43_V218_L3.1341.00
106_I110_L3.0671.00
59_I86_M2.8761.00
74_D176_F2.7971.00
194_Q250_E2.7591.00
60_E63_M2.5631.00
139_L197_I2.5541.00
190_R248_G2.5091.00
125_I203_R2.4931.00
106_I112_W2.4591.00
186_E248_G2.3891.00
135_G193_A2.3361.00
190_R194_Q2.3191.00
219_A225_K2.3061.00
131_E196_L2.2911.00
181_I193_A2.2081.00
109_N112_W2.0971.00
105_K109_N2.0751.00
210_H228_R2.0541.00
138_F181_I2.0150.99
92_V159_L1.9210.99
204_G236_Y1.9190.99
95_L158_P1.8860.99
106_I109_N1.8750.99
92_V148_L1.8580.99
97_K103_G1.8510.99
142_R174_I1.8450.99
129_M192_L1.8260.99
241_A251_L1.7880.99
105_K112_W1.7450.99
103_G109_N1.7210.98
103_G106_I1.6640.98
106_I111_L1.6620.98
148_L170_E1.6210.98
135_G197_I1.5860.97
95_L156_F1.5810.97
185_V193_A1.5590.97
129_M132_D1.5220.96
210_H230_D1.5160.96
103_G110_L1.5090.96
134_L181_I1.5050.96
233_R237_I1.4890.96
141_D144_G1.4810.96
103_G112_W1.4650.96
79_S86_M1.4480.95
69_A130_W1.4470.95
194_Q244_I1.4400.95
146_Y239_D1.4210.95
217_D221_K1.4210.95
45_L99_F1.4160.95
157_G161_R1.3950.94
132_D199_K1.3780.94
194_Q248_G1.3640.94
241_A245_A1.3590.93
148_L176_F1.3230.92
138_F243_L1.3170.92
107_A110_L1.3050.92
228_R231_E1.2890.91
138_F240_V1.2840.91
214_Y219_A1.2840.91
104_K110_L1.2820.91
46_K118_H1.2810.91
135_G181_I1.2710.91
103_G107_A1.2710.91
191_D195_A1.2470.90
106_I116_G1.2460.90
50_V213_S1.2450.90
138_F177_G1.2210.89
178_Y243_L1.2160.89
237_I241_A1.2050.88
58_S136_F1.1960.88
150_A235_L1.1900.88
139_L200_W1.1900.88
144_G170_E1.1780.87
110_L116_G1.1770.87
212_K217_D1.1770.87
145_L167_L1.1730.87
242_E246_P1.1720.87
205_L233_R1.1700.87
61_Q64_P1.1550.86
105_K110_L1.1510.86
108_E112_W1.1360.85
233_R236_Y1.1260.85
123_F140_I1.1260.85
103_G111_L1.1100.84
102_E105_K1.1060.84
142_R239_D1.1020.83
185_V247_L1.0970.83
85_E170_E1.0940.83
93_I108_E1.0870.83
234_Q237_I1.0840.82
91_Q162_I1.0840.82
95_L98_E1.0800.82
167_L171_E1.0680.81
141_D177_G1.0580.81
142_R146_Y1.0550.81
44_L48_L1.0350.79
110_L115_M1.0340.79
153_D221_K1.0320.79
217_D228_R1.0070.77
144_G148_L1.0030.77
103_G108_E1.0020.77
141_D148_L0.9970.77
193_A249_L0.9920.76
141_D176_F0.9820.76
185_V190_R0.9720.75
185_V194_Q0.9570.74
92_V144_G0.9560.74
58_S137_T0.9500.73
181_I243_L0.9480.73
55_E170_E0.9410.72
122_A140_I0.9320.72
150_A231_E0.9260.71
54_T144_G0.9200.71
149_L152_E0.9150.70
165_T172_F0.9130.70
97_K100_G0.9040.69
44_L219_A0.9030.69
85_E144_G0.8970.69
195_A198_N0.8970.69
90_W105_K0.8940.68
90_W161_R0.8890.68
175_N179_T0.8880.68
107_A112_W0.8790.67
201_F252_P0.8780.67
85_E141_D0.8730.67
230_D234_Q0.8710.66
112_W116_G0.8670.66
193_A248_G0.8620.66
198_N244_I0.8600.65
251_L254_V0.8570.65
125_I199_K0.8560.65
84_D196_L0.8510.65
195_A199_K0.8490.64
174_I239_D0.8480.64
102_E106_I0.8390.64
109_N113_T0.8390.64
237_I251_L0.8360.63
135_G196_L0.8290.63
54_T219_A0.8260.62
145_L171_E0.8260.62
145_L149_L0.8220.62
81_I176_F0.8170.61
236_Y240_V0.8160.61
107_A111_L0.8130.61
139_L240_V0.8120.61
99_F102_E0.8070.61
146_Y232_M0.8020.60
61_Q73_S0.8020.60
123_F127_F0.8010.60
146_Y235_L0.7980.60
178_Y239_D0.7970.60
134_L180_G0.7930.59
67_F75_R0.7890.59
133_T137_T0.7880.59
63_M79_S0.7860.58
149_L238_K0.7790.58
230_D233_R0.7790.58
98_E158_P0.7770.58
94_Q197_I0.7740.57
94_Q97_K0.7680.57
129_M196_L0.7680.57
127_F132_D0.7660.57
197_I242_E0.7570.56
84_D165_T0.7570.56
178_Y182_K0.7520.55
180_G183_R0.7510.55
127_F133_T0.7490.55
97_K101_E0.7370.54
188_G201_F0.7320.53
87_R169_E0.7130.51
130_W184_L0.7050.50
103_G116_G0.7030.50
49_T101_E0.7020.50
80_R83_V0.6990.50
65_W128_N0.6990.50
50_V214_Y0.6980.50
143_V147_Q0.6970.50
112_W115_M0.6920.49
133_T162_I0.6920.49
144_G176_F0.6900.49
71_K130_W0.6890.49
182_K246_P0.6870.49
62_H130_W0.6830.48
48_L158_P0.6790.48
75_R82_M0.6780.48
105_K108_E0.6750.47
85_E88_H0.6720.47
58_S123_F0.6720.47
156_F166_M0.6710.47
176_F180_G0.6670.47
46_K213_S0.6660.46
162_I166_M0.6640.46
45_L48_L0.6620.46
132_D255_N0.6600.46
218_L221_K0.6580.46
92_V141_D0.6540.45
231_E234_Q0.6520.45
55_E254_V0.6490.45
158_P161_R0.6470.45
63_M82_M0.6460.45
137_T141_D0.6460.45
143_V148_L0.6410.44
79_S82_M0.6360.44
90_W94_Q0.6360.44
92_V176_F0.6340.43
88_H156_F0.6340.43
199_K202_P0.6310.43
101_E111_L0.6300.43
211_S214_Y0.6270.43
71_K176_F0.6260.43
145_L239_D0.6260.43
59_I114_R0.6250.42
243_L247_L0.6240.42
198_N250_E0.6220.42
62_H82_M0.6210.42
222_Y253_D0.6200.42
234_Q241_A0.6140.41
229_N234_Q0.6130.41
83_V87_R0.6120.41
132_D196_L0.6090.41
54_T129_M0.6080.41
153_D245_A0.6060.41
191_D238_K0.6050.40
143_V171_E0.6040.40
44_L95_L0.6020.40
132_D200_W0.6010.40
113_T116_G0.5990.40
84_D172_F0.5980.40
205_L209_G0.5980.40
137_T177_G0.5960.40
94_Q161_R0.5930.39
125_I132_D0.5920.39
106_I117_R0.5920.39
242_E254_V0.5920.39
165_T196_L0.5900.39
145_L174_I0.5880.39
184_L193_A0.5880.39
55_E85_E0.5880.39
131_E184_L0.5850.39
208_F232_M0.5840.38
153_D195_A0.5820.38
182_K247_L0.5810.38
108_E111_L0.5800.38
164_P171_E0.5780.38
220_Y228_R0.5770.38
48_L95_L0.5760.38
57_A126_P0.5730.37
75_R79_S0.5730.37
69_A85_E0.5720.37
174_I178_Y0.5710.37
87_R172_F0.5710.37
59_I140_I0.5670.37
131_E190_R0.5650.37
122_A125_I0.5640.37
162_I165_T0.5620.36
164_P167_L0.5610.36
50_V236_Y0.5610.36
69_A79_S0.5600.36
147_Q170_E0.5600.36
102_E112_W0.5580.36
141_D224_I0.5580.36
130_W156_F0.5550.36
183_R186_E0.5550.36
235_L239_D0.5540.36
71_K74_D0.5530.36
126_P203_R0.5510.35
198_N253_D0.5500.35
77_T184_L0.5480.35
139_L204_G0.5480.35
69_A76_V0.5440.35
152_E164_P0.5430.35
210_H231_E0.5420.35
95_L137_T0.5380.34
64_P98_E0.5370.34
66_L79_S0.5350.34
63_M133_T0.5350.34
210_H229_N0.5350.34
195_A250_E0.5330.34
97_K104_K0.5320.34
176_F179_T0.5310.34
55_E88_H0.5310.34
133_T246_P0.5300.33
102_E108_E0.5230.33
121_D137_T0.5230.33
239_D242_E0.5210.33
154_S223_G0.5190.32
176_F236_Y0.5190.32
71_K76_V0.5190.32
59_I147_Q0.5190.32
142_R240_V0.5180.32
186_E189_K0.5150.32
47_L226_R0.5140.32
99_F222_Y0.5130.32
80_R165_T0.5100.32
197_I244_I0.5090.32
66_L91_Q0.5070.31
55_E71_K0.5070.31
152_E155_S0.5070.31
62_H86_M0.5070.31
59_I143_V0.5060.31
66_L179_T0.5050.31
214_Y217_D0.5050.31
74_D192_L0.5050.31
224_I231_E0.5030.31
49_T96_L0.5020.31
75_R136_F0.5020.31
104_K111_L0.5020.31
109_N115_M0.5010.31
46_K50_V0.5010.31
242_E250_E0.5010.31
243_L246_P0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3pf7A 1 0.9885 100 0.186 Contact Map
1otkA 2 0.8314 100 0.245 Contact Map
3pvtA 1 0.9502 100 0.289 Contact Map
4mudA 2 0.8467 100 0.358 Contact Map
3ge3A 2 0.977 98.7 0.864 Contact Map
2incA 2 0.977 98.7 0.866 Contact Map
1mtyB 2 0.9732 98.4 0.877 Contact Map
3ez0A 2 0.8008 98.3 0.881 Contact Map
1mtyD 2 0.9732 98.1 0.887 Contact Map
1mhyB 2 0.977 98 0.889 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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