GREMLIN Database
Q97YL0 - Ring oxydation complex/ phenylacetic acid degradation related protein
UniProt: Q97YL0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 234 (206)
Sequences: 1333 (715)
Seq/√Len: 49.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
163_Q167_N3.7331.00
26_A67_V3.5661.00
77_D80_E3.2511.00
24_L180_T2.9831.00
79_I82_I2.8961.00
78_V81_R2.7731.00
17_T187_H2.7401.00
92_L176_M2.6111.00
81_R85_A2.5691.00
48_S148_F2.5521.00
33_V60_L2.5351.00
79_I83_S2.5061.00
163_Q219_N2.5031.00
34_E37_S2.4771.00
111_L166_I2.4551.00
82_I85_A2.3891.00
107_A162_M2.3711.00
97_L172_R2.2581.00
81_R86_R2.2131.00
79_I85_A2.1801.00
159_K217_G2.1761.00
82_I86_R2.1341.00
83_S86_R2.1231.00
188_L194_S2.1211.00
103_E165_A2.0671.00
159_K163_Q2.0271.00
78_V82_I2.0101.00
78_V85_A2.0051.00
153_L162_M1.9650.99
78_V83_S1.9560.99
110_F153_L1.9030.99
85_A89_I1.8560.99
173_A205_Y1.8360.99
114_G146_I1.8220.99
66_L131_L1.8220.99
179_M197_T1.8200.99
77_D83_S1.7520.99
69_L130_P1.6670.98
19_V73_F1.6390.98
66_L120_L1.6350.98
79_I86_R1.6080.98
101_N161_R1.6050.98
210_N220_E1.5790.97
106_I153_L1.5350.97
76_K83_S1.4810.96
20_N90_H1.4710.96
69_L128_F1.4510.96
120_L142_E1.4430.96
160_N164_G1.4040.95
107_A166_I1.3830.95
202_I206_I1.3810.94
101_N104_D1.3570.94
186_T190_D1.3530.94
76_K82_I1.3400.94
104_D168_F1.3370.93
113_D116_G1.3320.93
179_M199_N1.3110.93
78_V86_R1.3060.93
129_E133_T1.2810.92
163_Q217_G1.2730.92
22_I73_F1.2710.92
43_A102_W1.2650.91
79_I89_I1.2600.91
157_Q162_M1.2500.91
86_R89_I1.2490.91
197_T200_D1.2420.91
110_F212_E1.2330.90
35_Q38_P1.2230.90
210_N214_K1.1970.89
80_E83_S1.1910.89
118_Y208_T1.1900.89
110_F149_S1.1880.89
185_E188_L1.1800.88
120_L148_F1.1790.88
81_R84_N1.1790.88
163_Q213_L1.1770.88
77_D81_R1.1750.88
181_W186_T1.1700.88
117_L139_I1.1650.88
53_A60_L1.1520.87
111_L169_W1.1500.87
65_Q134_L1.1380.86
110_F209_T1.1300.86
71_E77_D1.1300.86
82_I87_L1.1090.85
116_G142_E1.1080.85
206_I210_N1.1020.84
76_K79_I1.0930.84
122_I204_G1.0930.84
82_I89_I1.0900.84
77_D82_I1.0890.84
79_I84_N1.0860.84
79_I88_G1.0730.83
211_E215_K1.0720.83
76_K86_R1.0710.83
32_M108_F1.0580.82
157_Q216_C1.0510.82
114_G118_Y1.0260.80
59_E142_E1.0170.79
95_S112_V1.0060.79
72_E130_P1.0050.79
24_L184_N1.0000.78
18_L188_L0.9960.78
150_Q212_E0.9960.78
202_I205_Y0.9930.78
174_V202_I0.9870.77
139_I143_E0.9820.77
203_N206_I0.9750.76
170_F221_V0.9660.76
147_F151_N0.9590.75
107_A153_L0.9590.75
157_Q163_Q0.9540.75
122_I200_D0.9520.75
79_I87_L0.9510.75
69_L72_E0.9390.74
32_M109_T0.9350.73
64_W78_V0.9290.73
116_G120_L0.9290.73
199_N203_N0.9220.72
114_G208_T0.9110.71
18_L22_I0.9020.71
113_D120_L0.8980.70
206_I220_E0.8910.70
180_T184_N0.8900.70
66_L116_G0.8880.69
75_V80_E0.8800.69
162_M217_G0.8760.68
107_A165_A0.8740.68
94_V112_V0.8730.68
162_M218_Y0.8680.68
150_Q208_T0.8630.67
113_D149_S0.8630.67
150_Q154_R0.8610.67
113_D148_F0.8540.66
153_L212_E0.8480.66
117_L121_K0.8440.65
137_S144_S0.8430.65
78_V89_I0.8360.65
80_E84_N0.8360.65
29_E142_E0.8300.64
152_E155_N0.8240.64
67_V81_R0.8180.63
83_S87_L0.8110.62
164_G167_N0.8070.62
59_E116_G0.8050.62
205_Y209_T0.8030.62
31_A98_P0.8020.61
59_E113_D0.8020.61
166_I213_L0.7960.61
105_V109_T0.7950.61
97_L168_F0.7940.61
106_I152_E0.7880.60
28_F116_G0.7870.60
125_D190_D0.7760.59
37_S53_A0.7740.59
92_L112_V0.7740.59
71_E76_K0.7730.59
28_F92_L0.7730.59
58_D165_A0.7640.58
186_T197_T0.7630.58
41_V49_R0.7610.57
55_L148_F0.7540.57
91_K96_N0.7520.57
83_S89_I0.7470.56
199_N202_I0.7460.56
35_Q47_D0.7450.56
121_K124_K0.7420.55
164_G168_F0.7400.55
184_N187_H0.7390.55
130_P133_T0.7360.55
115_A119_Q0.7350.55
111_L209_T0.7340.55
117_L208_T0.7320.54
77_D86_R0.7310.54
49_R53_A0.7300.54
76_K85_A0.7300.54
71_E78_V0.7300.54
28_F188_L0.7260.54
20_N184_N0.7260.54
85_A88_G0.7210.53
61_N141_E0.7170.53
117_L143_E0.7150.53
76_K81_R0.7140.53
121_K207_K0.7130.53
100_F105_V0.7070.52
78_V87_L0.7030.52
78_V84_N0.6930.51
58_D137_S0.6910.50
77_D85_A0.6880.50
167_N213_L0.6850.50
146_I208_T0.6840.50
118_Y204_G0.6800.49
23_E75_V0.6780.49
64_W68_R0.6730.48
220_E223_Y0.6700.48
37_S56_V0.6690.48
101_N165_A0.6670.48
81_R89_I0.6660.48
89_I222_N0.6640.48
160_N207_K0.6630.47
62_H128_F0.6630.47
97_L104_D0.6600.47
68_R71_E0.6590.47
94_V213_L0.6590.47
187_H190_D0.6550.47
27_D35_Q0.6520.46
146_I150_Q0.6520.46
179_M200_D0.6510.46
168_F171_P0.6430.45
99_L104_D0.6420.45
207_K210_N0.6410.45
39_W100_F0.6350.45
66_L148_F0.6350.45
54_K57_S0.6340.44
64_W133_T0.6330.44
76_K80_E0.6310.44
80_E86_R0.6300.44
115_A143_E0.6300.44
212_E216_C0.6300.44
103_E156_Y0.6260.44
200_D203_N0.6250.44
191_L222_N0.6230.43
34_E84_N0.6230.43
24_L185_E0.6220.43
116_G148_F0.6220.43
68_R166_I0.6170.43
80_E89_I0.6160.43
148_F152_E0.6150.43
102_W156_Y0.6130.42
113_D193_I0.6120.42
66_L113_D0.6020.41
125_D214_K0.6000.41
102_W128_F0.5990.41
45_T102_W0.5940.40
128_F138_M0.5930.40
134_L138_M0.5930.40
118_Y201_L0.5930.40
157_Q218_Y0.5860.40
83_S88_G0.5860.40
59_E62_H0.5840.40
58_D144_S0.5830.39
92_L205_Y0.5820.39
154_R215_K0.5810.39
179_M198_K0.5800.39
93_E109_T0.5780.39
73_F128_F0.5770.39
166_I211_E0.5770.39
109_T113_D0.5740.39
148_F151_N0.5730.38
43_A59_E0.5710.38
167_N222_N0.5700.38
111_L173_A0.5700.38
61_N144_S0.5660.38
19_V22_I0.5660.38
28_F101_N0.5650.38
76_K87_L0.5610.37
157_Q217_G0.5590.37
82_I88_G0.5590.37
18_L73_F0.5580.37
189_R197_T0.5570.37
22_I130_P0.5540.37
36_Y102_W0.5520.36
179_M186_T0.5520.36
29_E116_G0.5480.36
29_E62_H0.5470.36
57_S61_N0.5470.36
154_R216_C0.5440.36
167_N219_N0.5430.36
77_D87_L0.5420.35
73_F191_L0.5420.35
99_L105_V0.5410.35
36_Y60_L0.5410.35
45_T148_F0.5410.35
167_N181_W0.5380.35
156_Y162_M0.5370.35
43_A53_A0.5360.35
16_N20_N0.5330.35
158_N161_R0.5320.35
67_V170_F0.5320.35
166_I218_Y0.5320.35
188_L193_I0.5310.34
22_I69_L0.5310.34
208_T211_E0.5280.34
165_A169_W0.5270.34
36_Y56_V0.5250.34
177_L202_I0.5250.34
104_D169_W0.5230.34
136_S139_I0.5230.34
134_L137_S0.5220.34
174_V178_H0.5200.33
213_L220_E0.5190.33
81_R88_G0.5180.33
55_L131_L0.5180.33
125_D210_N0.5170.33
162_M165_A0.5150.33
37_S105_V0.5140.33
104_D165_A0.5130.33
191_L196_L0.5130.33
51_F156_Y0.5130.33
20_N24_L0.5110.33
74_K157_Q0.5100.33
54_K137_S0.5070.32
95_S157_Q0.5050.32
198_K203_N0.5050.32
213_L217_G0.5040.32
109_T149_S0.5020.32
124_K136_S0.5010.32
54_K141_E0.5000.32
62_H102_W0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1otkA 2 0.9316 100 0.181 Contact Map
3pf7A 1 1 100 0.203 Contact Map
3pvtA 1 0.9957 100 0.227 Contact Map
4mudA 2 0.9487 100 0.252 Contact Map
2incA 2 0.9701 98.5 0.86 Contact Map
3ge3A 2 0.9786 98.5 0.861 Contact Map
1mtyB 2 0.9402 98.2 0.871 Contact Map
1mtyD 2 0.9786 98.1 0.875 Contact Map
3ez0A 2 0.8846 98.1 0.876 Contact Map
1mhyB 2 0.9744 98 0.878 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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