Q97YI0 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97YI0 - L-carnitine dehydratase, putative (CaiB)

UniProt:	Q97YI0	Sequences: MYRVIELGHVISAPFAGEILRHLGFEVIKIEPLLGDPSRKDDVLVDSMFVFNNRGKRSISVDLRKEKGKEVFLRLVRNSHVLIENLSPHVMDRLGLSDDVIFSTNPSLVYCSIKGYPKGKYENLPAFGTIIEAESGIMDANGKARLPASITDMNASTYCVITILWALLMKKPGHYRVSIIQANTVWLGYYLIAYQKYGKLFEAGKDELPFWAPYELFKSSEEKEFYLAVNDNEKFTKLCKALGLEDLLADERFKTNADRVRNRKILHEKLQQKFSSMKLEEIMNILRYNDIPVGKLNNLKDLISNELVEWDTFRNVQVPKLPLPGSLNSQHVPNVGEDTLYILKELGYSENEIESMIKENVINYNK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	366 (346)
Sequences:	10438 (6933)
Seq/√Len:	372.7

ECOLI - FCTA CAIB ACOCT
SULSO - Q97YI0 Q97U79

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
97_S	100_V	3.645	1.00
26_E	57_R	3.540	1.00
277_M	281_E	3.184	1.00
17_G	83_I	3.151	1.00
111_C	163_I	3.082	1.00
111_C	159_C	2.964	1.00
65_K	68_G	2.855	1.00
77_R	104_T	2.809	1.00
73_L	104_T	2.763	1.00
92_D	97_S	2.640	1.00
219_S	279_L	2.619	1.00
101_I	108_L	2.566	1.00
277_M	282_I	2.539	1.00
69_K	73_L	2.504	1.00
98_D	102_F	2.488	1.00
169_M	174_H	2.472	1.00
61_V	72_F	2.469	1.00
3_R	26_E	2.468	1.00
220_S	278_K	2.395	1.00
278_K	281_E	2.369	1.00
277_M	285_I	2.336	1.00
336_G	339_T	2.264	1.00
218_K	275_S	2.229	1.00
74_R	77_R	2.209	1.00
70_E	74_R	2.172	1.00
273_K	276_S	2.169	1.00
81_V	163_I	2.121	1.00
71_V	348_Y	2.092	1.00
7_L	72_F	2.091	1.00
262_N	265_I	1.952	1.00
268_E	272_Q	1.944	1.00
339_T	343_L	1.940	1.00
338_D	341_Y	1.940	1.00
57_R	341_Y	1.914	1.00
3_R	78_N	1.898	1.00
100_V	103_S	1.885	1.00
118_K	176_R	1.872	1.00
151_T	183_N	1.871	1.00
5_I	76_V	1.851	1.00
269_K	272_Q	1.833	1.00
169_M	172_P	1.831	1.00
23_L	165_W	1.813	1.00
244_L	273_K	1.807	1.00
161_I	164_L	1.791	1.00
169_M	327_L	1.788	1.00
124_L	287_R	1.770	1.00
298_N	301_D	1.760	1.00
62_D	65_K	1.759	1.00
215_E	267_H	1.747	1.00
91_M	96_L	1.743	1.00
121_Y	124_L	1.736	1.00
21_R	55_G	1.704	1.00
252_R	265_I	1.702	1.00
82_L	108_L	1.698	1.00
121_Y	305_N	1.689	1.00
76_V	101_I	1.685	1.00
5_I	79_S	1.679	1.00
334_N	337_E	1.673	1.00
244_L	247_L	1.673	1.00
2_Y	167_L	1.654	1.00
57_R	345_E	1.648	1.00
6_E	17_G	1.646	1.00
98_D	110_Y	1.639	1.00
280_E	284_N	1.638	1.00
181_Q	310_W	1.617	1.00
133_A	226_Y	1.611	1.00
61_V	68_G	1.586	1.00
240_K	245_E	1.547	1.00
241_A	285_I	1.531	1.00
66_E	69_K	1.528	1.00
255_T	258_D	1.525	1.00
273_K	282_I	1.523	1.00
22_H	54_R	1.514	1.00
284_N	288_Y	1.509	1.00
76_V	105_N	1.507	1.00
135_S	183_N	1.503	1.00
279_L	301_D	1.497	1.00
270_L	274_F	1.494	1.00
180_I	308_V	1.490	1.00
244_L	269_K	1.470	1.00
240_K	248_L	1.469	1.00
304_S	309_E	1.438	1.00
142_G	203_A	1.435	1.00
219_S	225_F	1.432	1.00
109_V	170_K	1.429	1.00
331_H	337_E	1.420	1.00
340_L	344_K	1.412	1.00
59_I	342_I	1.407	1.00
154_N	186_W	1.407	1.00
218_K	271_Q	1.403	1.00
258_D	261_R	1.396	1.00
61_V	71_V	1.394	1.00
107_S	170_K	1.393	1.00
59_I	339_T	1.389	1.00
74_R	348_Y	1.384	1.00
84_E	112_S	1.381	1.00
281_E	285_I	1.369	1.00
174_H	326_S	1.357	1.00
333_P	338_D	1.355	1.00
265_I	268_E	1.353	1.00
247_L	269_K	1.350	1.00
217_F	267_H	1.341	1.00
279_L	295_K	1.329	1.00
254_K	258_D	1.327	1.00
75_L	346_L	1.320	1.00
218_K	224_E	1.320	1.00
236_T	249_A	1.317	1.00
238_L	242_L	1.315	1.00
121_Y	134_E	1.304	1.00
73_L	100_V	1.303	1.00
113_I	159_C	1.300	1.00
162_T	323_L	1.293	1.00
4_V	81_V	1.293	1.00
300_K	304_S	1.284	1.00
274_F	282_I	1.282	1.00
237_K	240_K	1.275	1.00
174_H	328_N	1.275	1.00
73_L	96_L	1.272	1.00
236_T	240_K	1.256	1.00
164_L	168_L	1.247	1.00
242_L	273_K	1.246	1.00
241_A	289_N	1.234	1.00
90_V	93_R	1.234	1.00
235_F	239_C	1.233	1.00
232_N	236_T	1.222	1.00
33_L	60_S	1.221	1.00
128_G	132_E	1.200	1.00
7_L	82_L	1.199	1.00
178_S	181_Q	1.196	1.00
67_K	70_E	1.194	1.00
218_K	274_F	1.193	1.00
168_L	171_K	1.190	1.00
184_T	308_V	1.183	1.00
233_E	237_K	1.167	1.00
158_Y	185_V	1.162	1.00
55_G	330_Q	1.146	1.00
120_K	307_L	1.141	1.00
225_F	282_I	1.136	1.00
283_M	293_V	1.132	1.00
91_M	110_Y	1.128	1.00
63_L	94_L	1.118	1.00
281_E	284_N	1.116	1.00
229_V	238_L	1.113	1.00
80_H	170_K	1.113	1.00
200_L	300_K	1.104	1.00
60_S	339_T	1.104	1.00
162_T	175_Y	1.101	1.00
71_V	346_L	1.101	1.00
16_A	160_V	1.100	1.00
132_E	151_T	1.092	1.00
126_A	131_I	1.091	1.00
2_Y	168_L	1.090	1.00
297_N	305_N	1.087	1.00
76_V	104_T	1.084	1.00
64_R	94_L	1.082	1.00
126_A	179_I	1.078	1.00
167_L	170_K	1.068	1.00
36_D	39_R	1.065	1.00
184_T	302_L	1.062	1.00
134_E	305_N	1.058	1.00
222_E	279_L	1.049	1.00
225_F	274_F	1.039	1.00
116_Y	134_E	1.039	1.00
283_M	295_K	1.029	1.00
19_I	161_I	1.027	1.00
200_L	298_N	1.025	1.00
252_R	262_N	1.024	1.00
58_S	333_P	1.018	1.00
214_Y	228_A	1.018	1.00
280_E	283_M	1.014	1.00
5_I	72_F	1.011	1.00
330_Q	338_D	1.009	1.00
101_I	110_Y	1.009	1.00
272_Q	276_S	1.007	1.00
238_L	270_L	1.000	1.00
265_I	269_K	0.997	1.00
174_H	327_L	0.994	1.00
3_R	28_I	0.992	1.00
71_V	74_R	0.989	1.00
84_E	91_M	0.985	1.00
16_A	159_C	0.982	1.00
187_L	299_L	0.979	1.00
218_K	222_E	0.972	1.00
285_I	288_Y	0.971	1.00
73_L	77_R	0.970	1.00
286_L	293_V	0.961	1.00
72_F	96_L	0.960	1.00
7_L	91_M	0.960	1.00
8_G	13_A	0.958	1.00
3_R	79_S	0.950	1.00
31_E	39_R	0.948	1.00
77_R	105_N	0.948	1.00
18_E	22_H	0.947	1.00
240_K	289_N	0.946	1.00
166_A	174_H	0.942	1.00
81_V	109_V	0.942	1.00
280_E	295_K	0.936	1.00
169_M	328_N	0.931	1.00
207_E	263_R	0.930	1.00
18_E	54_R	0.929	1.00
172_P	327_L	0.928	1.00
69_K	96_L	0.923	1.00
66_E	70_E	0.921	1.00
160_V	164_L	0.920	1.00
235_F	259_R	0.916	1.00
297_N	301_D	0.913	1.00
284_N	287_R	0.906	1.00
82_L	101_I	0.903	1.00
253_F	265_I	0.901	1.00
129_T	228_A	0.897	1.00
318_V	334_N	0.897	1.00
86_L	90_V	0.891	1.00
161_I	168_L	0.890	1.00
21_R	27_V	0.890	1.00
68_G	71_V	0.890	1.00
237_K	241_A	0.889	1.00
158_Y	182_A	0.888	1.00
253_F	262_N	0.888	1.00
53_N	56_K	0.887	1.00
236_T	248_L	0.885	1.00
285_I	289_N	0.882	1.00
45_V	318_V	0.881	1.00
72_F	76_V	0.879	1.00
114_K	117_P	0.878	1.00
271_Q	275_S	0.876	1.00
81_V	167_L	0.874	1.00
279_L	283_M	0.873	1.00
70_E	73_L	0.872	1.00
10_V	127_F	0.872	1.00
256_N	260_V	0.871	1.00
341_Y	345_E	0.868	1.00
71_V	343_L	0.867	1.00
30_I	72_F	0.866	1.00
12_S	113_I	0.865	1.00
30_I	59_I	0.864	1.00
271_Q	274_F	0.862	1.00
82_L	91_M	0.855	1.00
225_F	283_M	0.854	1.00
20_L	163_I	0.851	1.00
194_Y	300_K	0.851	1.00
26_E	341_Y	0.850	1.00
181_Q	312_T	0.844	1.00
216_L	226_Y	0.844	1.00
115_G	126_A	0.844	1.00
225_F	279_L	0.841	1.00
28_I	342_I	0.839	1.00
226_Y	294_G	0.839	1.00
269_K	273_K	0.838	1.00
3_R	57_R	0.836	1.00
129_T	226_Y	0.835	1.00
15_F	19_I	0.835	1.00
307_L	310_W	0.834	1.00
133_A	294_G	0.833	1.00
72_F	82_L	0.833	1.00
92_D	99_D	0.832	1.00
134_E	297_N	0.830	1.00
49_F	53_N	0.828	1.00
97_S	110_Y	0.824	1.00
73_L	105_N	0.822	1.00
194_Y	200_L	0.821	1.00
68_G	343_L	0.820	1.00
220_S	281_E	0.817	1.00
23_L	161_I	0.816	1.00
8_G	17_G	0.813	1.00
78_N	345_E	0.811	1.00
82_L	110_Y	0.809	1.00
144_A	224_E	0.803	1.00
107_S	172_P	0.798	1.00
326_S	329_S	0.797	1.00
73_L	76_V	0.795	1.00
60_S	335_V	0.794	1.00
251_E	254_K	0.792	1.00
92_D	112_S	0.790	1.00
131_I	151_T	0.789	1.00
69_K	95_G	0.789	1.00
278_K	282_I	0.788	1.00
242_L	270_L	0.788	1.00
139_D	298_N	0.783	1.00
283_M	287_R	0.783	1.00
100_V	104_T	0.781	1.00
243_G	285_I	0.779	1.00
119_G	307_L	0.779	1.00
111_C	175_Y	0.774	1.00
220_S	276_S	0.774	1.00
59_I	71_V	0.773	1.00
99_D	102_F	0.772	1.00
71_V	347_G	0.771	1.00
333_P	337_E	0.770	1.00
68_G	348_Y	0.770	1.00
109_V	166_A	0.768	1.00
90_V	94_L	0.767	1.00
314_R	320_K	0.766	1.00
5_I	82_L	0.765	1.00
133_A	138_M	0.765	1.00
35_G	39_R	0.764	1.00
26_E	345_E	0.761	1.00
225_F	293_V	0.760	1.00
87_S	90_V	0.759	1.00
237_K	289_N	0.757	1.00
143_K	215_E	0.755	1.00
30_I	61_V	0.753	1.00
69_K	94_L	0.750	1.00
216_L	296_L	0.749	1.00
161_I	165_W	0.747	1.00
320_K	324_P	0.747	1.00
59_I	343_L	0.745	1.00
98_D	108_L	0.745	1.00
312_T	324_P	0.743	1.00
58_S	336_G	0.742	1.00
308_V	312_T	0.741	1.00
253_F	269_K	0.740	1.00
84_E	118_K	0.740	1.00
305_N	308_V	0.739	1.00
287_R	293_V	0.739	1.00
35_G	335_V	0.738	1.00
308_V	313_F	0.734	1.00
191_L	195_Q	0.734	1.00
268_E	271_Q	0.732	1.00
184_T	312_T	0.729	1.00
157_T	161_I	0.728	1.00
267_H	271_Q	0.726	1.00
191_L	303_I	0.724	1.00
29_K	36_D	0.722	1.00
140_A	187_L	0.720	1.00
16_A	83_I	0.715	1.00
11_I	52_N	0.715	1.00
76_V	96_L	0.714	1.00
89_H	92_D	0.712	1.00
74_R	78_N	0.712	1.00
176_R	310_W	0.709	0.99
23_L	325_G	0.705	0.99
130_I	294_G	0.702	0.99
68_G	72_F	0.697	0.99
151_T	155_A	0.697	0.99
311_D	324_P	0.696	0.99
212_A	260_V	0.696	0.99
295_K	301_D	0.696	0.99
89_H	123_N	0.695	0.99
28_I	79_S	0.694	0.99
22_H	55_G	0.692	0.99
215_E	271_Q	0.691	0.99
104_T	107_S	0.690	0.99
121_Y	307_L	0.690	0.99
155_A	182_A	0.689	0.99
14_P	152_D	0.688	0.99
6_E	13_A	0.687	0.99
134_E	295_K	0.687	0.99
212_A	267_H	0.687	0.99
272_Q	275_S	0.686	0.99
70_E	104_T	0.686	0.99
264_K	268_E	0.683	0.99
276_S	282_I	0.679	0.99
87_S	125_P	0.679	0.99
5_I	78_N	0.678	0.99
117_P	176_R	0.677	0.99
303_I	313_F	0.676	0.99
154_N	157_T	0.674	0.99
234_K	292_P	0.671	0.99
109_V	168_L	0.670	0.99
266_L	270_L	0.669	0.99
50_V	332_V	0.668	0.99
155_A	179_I	0.668	0.99
19_I	160_V	0.666	0.99
194_Y	198_G	0.666	0.99
231_D	234_K	0.665	0.99
98_D	112_S	0.665	0.99
227_L	274_F	0.665	0.99
207_E	267_H	0.664	0.99
105_N	108_L	0.663	0.99
237_K	290_D	0.663	0.99
60_S	336_G	0.663	0.99
61_V	343_L	0.662	0.99
141_N	147_P	0.659	0.99
78_N	346_L	0.658	0.99
177_V	182_A	0.657	0.99
84_E	89_H	0.656	0.99
114_K	176_R	0.654	0.99
6_E	9_H	0.653	0.99
50_V	318_V	0.652	0.99
15_F	153_M	0.649	0.99
140_A	299_L	0.647	0.99
134_E	294_G	0.647	0.99
253_F	266_L	0.646	0.99
68_G	347_G	0.644	0.99
239_C	245_E	0.643	0.99
174_H	325_G	0.642	0.99
9_H	37_P	0.641	0.99
15_F	185_V	0.640	0.99
137_I	187_L	0.640	0.99
74_R	346_L	0.638	0.99
20_L	160_V	0.636	0.99
125_P	290_D	0.636	0.99
154_N	182_A	0.635	0.99
99_D	103_S	0.635	0.99
5_I	75_L	0.631	0.99
57_R	330_Q	0.628	0.99
257_A	261_R	0.627	0.99
227_L	293_V	0.626	0.99
180_I	307_L	0.625	0.99
137_I	146_L	0.623	0.99
129_T	214_Y	0.623	0.99
127_F	292_P	0.623	0.99
260_V	263_R	0.622	0.99
166_A	175_Y	0.622	0.99
63_L	72_F	0.620	0.99
45_V	50_V	0.618	0.99
219_S	282_I	0.617	0.99
11_I	149_S	0.615	0.99
127_F	231_D	0.614	0.99
156_S	160_V	0.611	0.99
137_I	183_N	0.608	0.98
159_C	177_V	0.607	0.98
207_E	215_E	0.607	0.98
311_D	314_R	0.605	0.98
256_N	259_R	0.603	0.98
17_G	56_K	0.603	0.98
330_Q	341_Y	0.602	0.98
2_Y	170_K	0.600	0.98
227_L	238_L	0.600	0.98
302_L	308_V	0.598	0.98
92_D	100_V	0.597	0.98
81_V	170_K	0.596	0.98
58_S	337_E	0.595	0.98
58_S	335_V	0.595	0.98
221_E	279_L	0.595	0.98
225_F	286_L	0.594	0.98
159_C	163_I	0.593	0.98
12_S	155_A	0.592	0.98
160_V	165_W	0.591	0.98
219_S	222_E	0.584	0.98
250_D	253_F	0.583	0.98
221_E	278_K	0.582	0.98
39_R	49_F	0.581	0.98
88_P	114_K	0.578	0.98
219_S	274_F	0.577	0.98
28_I	78_N	0.577	0.98
10_V	37_P	0.575	0.98
84_E	110_Y	0.575	0.98
73_L	95_G	0.574	0.98
325_G	328_N	0.573	0.98
252_R	269_K	0.573	0.98
15_F	156_S	0.570	0.98
113_I	155_A	0.570	0.98
221_E	280_E	0.570	0.98
123_N	287_R	0.568	0.98
13_A	83_I	0.568	0.98
76_V	82_L	0.567	0.98
153_M	188_G	0.566	0.98
112_S	118_K	0.565	0.98
246_D	269_K	0.565	0.98
43_V	47_S	0.565	0.98
325_G	329_S	0.562	0.97
89_H	97_S	0.561	0.97
232_N	259_R	0.560	0.97
52_N	153_M	0.560	0.97
31_E	35_G	0.559	0.97
258_D	262_N	0.559	0.97
220_S	275_S	0.559	0.97
193_A	210_F	0.559	0.97
341_Y	344_K	0.557	0.97
102_F	110_Y	0.555	0.97
7_L	63_L	0.555	0.97
58_S	338_D	0.554	0.97
127_F	130_I	0.553	0.97
104_T	108_L	0.552	0.97
92_D	118_K	0.552	0.97
135_S	180_I	0.551	0.97
16_A	156_S	0.550	0.97
319_P	334_N	0.548	0.97
151_T	179_I	0.547	0.97
17_G	27_V	0.547	0.97
60_S	71_V	0.545	0.97
76_V	79_S	0.545	0.97
141_N	145_R	0.542	0.97
89_H	93_R	0.542	0.97
306_E	309_E	0.542	0.97
343_L	346_L	0.541	0.97
29_K	35_G	0.541	0.97
57_R	338_D	0.539	0.97
45_V	334_N	0.538	0.97
6_E	56_K	0.538	0.97
270_L	273_K	0.537	0.97
241_A	288_Y	0.537	0.97
330_Q	337_E	0.536	0.97
245_E	248_L	0.531	0.96
238_L	286_L	0.531	0.96
342_I	345_E	0.530	0.96
342_I	346_L	0.528	0.96
165_W	325_G	0.527	0.96
165_W	168_L	0.526	0.96
242_L	245_E	0.526	0.96
241_A	291_I	0.524	0.96
87_S	290_D	0.522	0.96
155_A	177_V	0.519	0.96
319_P	337_E	0.515	0.96
175_Y	325_G	0.515	0.96
31_E	58_S	0.514	0.96
73_L	91_M	0.514	0.96
282_I	285_I	0.514	0.96
138_M	216_L	0.514	0.96
81_V	164_L	0.514	0.96
34_L	40_K	0.513	0.96
131_I	179_I	0.512	0.96
130_I	292_P	0.512	0.96
28_I	75_L	0.512	0.96
146_L	150_I	0.512	0.96
97_S	103_S	0.511	0.96
212_A	263_R	0.510	0.96
339_T	344_K	0.509	0.95
3_R	346_L	0.509	0.95
13_A	113_I	0.505	0.95
153_M	186_W	0.505	0.95
65_K	69_K	0.505	0.95
98_D	174_H	0.503	0.95
234_K	237_K	0.503	0.95
2_Y	164_L	0.502	0.95
259_R	262_N	0.500	0.95
88_P	118_K	0.500	0.95
102_F	107_S	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1q7eA	2	0.9699	100	0.092	Contact Map
2vjqA	2	0.9863	100	0.096	Contact Map
3ubmA	2	0.9918	100	0.1	Contact Map
1xk7A	2	0.9863	100	0.113	Contact Map
4ed9A	2	0.9454	100	0.128	Contact Map
4hl6A	2	0.9481	100	0.141	Contact Map
2yimA	2	0.8989	100	0.191	Contact Map
2g04A	2	0.8907	100	0.221	Contact Map
1vl6A	4	0.5219	93.9	0.947	Contact Map
2a9fA	2	0.5328	85.1	0.956	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0115 seconds.