GREMLIN Database
Q97Y82 - Uncharacterized protein
UniProt: Q97Y82 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 139 (117)
Sequences: 3954 (2680)
Seq/√Len: 247.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
90_D120_Y3.1161.00
82_D110_R3.0261.00
90_D119_R2.9491.00
36_I93_I2.9331.00
56_S62_V2.9031.00
53_G89_K2.8581.00
51_D90_D2.7421.00
77_E87_R2.7151.00
36_I125_L2.6231.00
53_G92_I2.6101.00
33_A68_E2.4591.00
34_E68_E2.2781.00
96_V124_V2.1571.00
33_A64_K2.1501.00
40_I54_V2.0731.00
32_V95_S1.9981.00
28_K64_K1.9951.00
99_T127_N1.9931.00
94_F114_A1.8731.00
77_E89_K1.8621.00
39_A125_L1.6551.00
91_V121_K1.6081.00
79_N83_A1.5611.00
98_A103_R1.4401.00
48_I51_D1.4371.00
89_K92_I1.4361.00
57_P81_V1.4171.00
96_V131_I1.4111.00
40_I69_L1.3601.00
53_G84_F1.3561.00
100_N130_S1.3491.00
56_S97_T1.2881.00
37_V68_E1.2601.00
62_V66_D1.2591.00
35_E125_L1.2581.00
64_K68_E1.2511.00
69_L78_V1.2411.00
39_A123_I1.2311.00
39_A93_I1.2251.00
88_E104_F1.2251.00
58_Y104_F1.1781.00
36_I54_V1.1691.00
99_T130_S1.1301.00
33_A37_V1.1081.00
41_K72_Y1.0921.00
36_I95_S1.0811.00
64_K67_Q1.0431.00
46_K50_Q1.0301.00
30_Y64_K1.0271.00
62_V78_V1.0021.00
36_I40_I1.0011.00
91_V123_I1.0001.00
55_I89_K0.9971.00
30_Y68_E0.9961.00
65_L78_V0.9711.00
84_F89_K0.9511.00
37_V41_K0.9431.00
33_A65_L0.9431.00
41_K45_S0.9411.00
44_I49_G0.9341.00
126_G131_I0.9321.00
102_L105_V0.9221.00
110_R113_V0.9041.00
115_F122_L0.9031.00
81_V114_A0.9021.00
43_L91_V0.9001.00
57_P94_F0.9001.00
128_E132_M0.8971.00
44_I52_V0.8901.00
93_I125_L0.8620.99
27_G101_G0.8610.99
60_T63_R0.8580.99
116_T121_K0.8570.99
127_N130_S0.8570.99
50_Q90_D0.8500.99
31_K34_E0.8490.99
56_S65_L0.8390.99
107_N111_L0.8320.99
58_Y98_A0.8270.99
27_G98_A0.8250.99
62_V83_A0.8230.99
72_Y75_Y0.8210.99
40_I44_I0.8180.99
30_Y34_E0.8170.99
83_A88_E0.8170.99
85_Q113_V0.8090.99
18_K22_T0.8080.99
26_S88_E0.8080.99
47_L50_Q0.8050.99
98_A110_R0.8000.99
26_S104_F0.7950.99
94_F124_V0.7860.99
47_L51_D0.7820.99
88_E103_R0.7810.99
40_I52_V0.7700.99
26_S60_T0.7660.99
94_F122_L0.7640.99
55_I83_A0.7640.99
31_K35_E0.7560.99
49_G75_Y0.7520.98
85_Q114_A0.7380.98
35_E38_K0.7320.98
38_K41_K0.7260.98
35_E39_A0.7230.98
79_N84_F0.7180.98
57_P105_V0.7170.98
27_G97_T0.7140.98
21_D28_K0.6990.98
57_P111_L0.6970.98
51_D89_K0.6950.97
19_K30_Y0.6940.97
59_R83_A0.6890.97
58_Y82_D0.6760.97
55_I92_I0.6700.97
71_N74_P0.6640.97
79_N121_K0.6630.97
118_P122_L0.6590.97
105_V131_I0.6580.97
24_Q60_T0.6490.96
70_A75_Y0.6480.96
56_S95_S0.6450.96
57_P114_A0.6440.96
104_F112_N0.6430.96
59_R62_V0.6380.96
35_E42_F0.6320.96
39_A121_K0.6310.96
34_E37_V0.6200.95
41_K71_N0.6110.95
18_K21_D0.6110.95
34_E38_K0.6090.95
59_R66_D0.6060.95
19_K22_T0.6060.95
54_V76_V0.6050.94
21_D25_A0.6010.94
129_N132_M0.5980.94
104_F110_R0.5950.94
38_K42_F0.5950.94
65_L95_S0.5920.94
20_G24_Q0.5860.94
59_R80_T0.5850.93
57_P112_N0.5820.93
20_G23_I0.5810.93
106_T116_T0.5800.93
100_N103_R0.5790.93
109_R119_R0.5750.93
18_K23_I0.5710.93
30_Y75_Y0.5680.92
19_K70_A0.5680.92
37_V65_L0.5670.92
83_A104_F0.5610.92
39_A115_F0.5610.92
70_A74_P0.5590.92
55_I114_A0.5580.92
36_I39_A0.5540.91
28_K60_T0.5510.91
37_V69_L0.5470.91
95_S118_P0.5380.90
43_L52_V0.5360.90
46_K49_G0.5360.90
20_G28_K0.5350.90
28_K33_A0.5350.90
48_I67_Q0.5330.90
97_T124_V0.5260.89
42_F47_L0.5250.89
28_K67_Q0.5190.89
48_I72_Y0.5190.89
29_A118_P0.5190.89
28_K63_R0.5180.89
49_G76_V0.5170.88
122_L130_S0.5160.88
79_N87_R0.5150.88
84_F110_R0.5130.88
102_L106_T0.5120.88
41_K74_P0.5120.88
116_T120_Y0.5040.87
22_T71_N0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4b3fX 1 0.9496 100 0.336 Contact Map
2xzlA 1 1 100 0.378 Contact Map
2wjyA 1 1 100 0.388 Contact Map
2gk6A 1 0.9784 100 0.4 Contact Map
4pj3A 1 0.9856 99.9 0.422 Contact Map
3vkwA 1 0.8993 99.7 0.612 Contact Map
3dmnA 1 0.9353 99.6 0.636 Contact Map
4n0nA 1 0.7554 99.5 0.653 Contact Map
3e1sA 1 0.9856 99.4 0.677 Contact Map
1w36D 1 0.6978 99 0.725 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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