Q97Y81 - SULSO - GREMLIN Contacts

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Q97Y81 - Glutamate dehydrogenase

UniProt:	Q97Y81	Sequences: MEELLTSNLLVQQVKKLYKVGELLGLDSETIDVLSQPERVMQVKIQIRSSDGKLRTFIGWRSQHNSALGPYKGGVRYGPNVTQDEVIALSMIMTWKNSLLLLPYGGGKGGIRVDPKKLTLKELEDLSRKYVQLIHKYLGSDVDIPAPDINTNPQTMAWFLDEYIKITGKVDFAVFTGKPSELGGIGVRLYSTGLGVATIARDAANKFIGGIEGSRVIIQGFGNVGFFTAKFLSEMGAKIIGVSDIGGGVINENGIDVNRALEVVQSTGSVVNYLEGKKVTNEELLISDCDILIPAAVENVINKFNAPKVRAKLIVEGANGPLTADADEIMKQRGVIVIPDILANAGGVVGSYVEWANNRSGGIISDEEAKKLIVDRMINAFNTLYDFHKRKFADQDLRTVAMALAVDRVVGAMKARGLL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	419 (366)
Sequences:	5273 (2550)
Seq/√Len:	133.3

ECOLI - DHE4
BACSU - DHE2 GUDB DHLE
HALSA - DHEB DHE4 DHE
SULSO - Q97Y81 Q97X22 DHE2 Q97WS2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
232_L	237_A	4.251	1.00
286_I	308_K	3.768	1.00
218_I	229_A	3.728	1.00
289_C	311_A	3.309	1.00
217_I	289_C	3.306	1.00
262_E	266_S	3.009	1.00
200_A	315_V	2.998	1.00
288_D	310_R	2.918	1.00
256_D	259_R	2.859	1.00
328_E	332_Q	2.780	1.00
114_D	117_K	2.539	1.00
97_N	348_V	2.511	1.00
104_Y	352_Y	2.496	1.00
132_Q	162_E	2.462	1.00
215_R	238_K	2.408	1.00
121_K	125_D	2.405	1.00
202_D	205_N	2.387	1.00
229_A	242_V	2.347	1.00
331_K	396_D	2.344	1.00
387_F	391_K	2.335	1.00
149_I	297_V	2.292	1.00
202_D	378_I	2.289	1.00
209_G	214_S	2.252	1.00
49_S	55_R	2.248	1.00
280_T	283_E	2.196	1.00
199_I	343_A	2.182	1.00
196_V	317_G	2.130	1.00
216_V	232_L	2.129	1.00
230_K	234_E	2.129	1.00
64_H	90_S	2.127	1.00
381_F	385_Y	2.123	1.00
206_K	389_K	2.112	1.00
396_D	399_T	2.083	1.00
152_N	155_T	2.077	1.00
315_V	343_A	2.019	1.00
303_K	325_D	2.011	1.00
387_F	407_D	1.998	1.00
216_V	237_A	1.998	1.00
407_D	411_G	1.993	1.00
46_Q	129_K	1.992	1.00
132_Q	165_K	1.956	1.00
202_D	382_N	1.953	1.00
322_L	330_M	1.938	1.00
386_D	390_R	1.936	1.00
330_M	335_V	1.934	1.00
206_K	385_Y	1.916	1.00
261_L	265_Q	1.912	1.00
338_I	343_A	1.909	1.00
241_G	284_L	1.907	1.00
75_V	159_F	1.901	1.00
368_E	372_L	1.855	1.00
187_V	366_D	1.853	1.00
113_V	118_L	1.842	1.00
197_A	235_M	1.807	1.00
306_A	329_I	1.804	1.00
62_S	90_S	1.789	1.00
252_E	277_K	1.782	1.00
285_L	292_L	1.775	1.00
203_A	313_L	1.771	1.00
68_L	101_L	1.752	1.00
71_Y	107_G	1.751	1.00
211_I	237_A	1.749	1.00
302_N	305_N	1.733	1.00
341_I	402_M	1.715	1.00
181_E	411_G	1.712	1.00
131_V	159_F	1.646	1.00
324_A	327_D	1.643	1.00
329_I	333_R	1.636	1.00
99_L	342_L	1.632	1.00
201_R	235_M	1.618	1.00
206_K	381_F	1.605	1.00
201_R	374_V	1.604	1.00
395_Q	400_V	1.600	1.00
217_I	241_G	1.599	1.00
242_V	260_A	1.592	1.00
157_A	179_P	1.583	1.00
389_K	394_D	1.581	1.00
395_Q	403_A	1.568	1.00
50_S	119_T	1.567	1.00
135_H	167_T	1.566	1.00
198_T	201_R	1.543	1.00
366_D	370_K	1.494	1.00
301_I	322_L	1.489	1.00
59_G	130_Y	1.475	1.00
301_I	309_V	1.472	1.00
203_A	338_I	1.458	1.00
318_A	321_P	1.451	1.00
82_T	85_E	1.446	1.00
198_T	374_V	1.445	1.00
204_A	291_I	1.398	1.00
216_V	293_I	1.394	1.00
210_G	213_G	1.393	1.00
228_T	293_I	1.387	1.00
162_E	165_K	1.386	1.00
119_T	122_E	1.373	1.00
245_I	264_V	1.365	1.00
315_V	338_I	1.362	1.00
248_G	279_V	1.361	1.00
303_K	329_I	1.358	1.00
78_G	297_V	1.356	1.00
196_V	315_V	1.352	1.00
66_S	71_Y	1.348	1.00
206_K	382_N	1.338	1.00
382_N	386_D	1.336	1.00
153_P	189_L	1.335	1.00
48_R	121_K	1.328	1.00
375_D	379_N	1.327	1.00
374_V	378_I	1.318	1.00
241_G	287_S	1.313	1.00
64_H	94_T	1.297	1.00
135_H	166_I	1.275	1.00
381_F	397_L	1.269	1.00
246_G	269_S	1.267	1.00
129_K	132_Q	1.266	1.00
358_N	363_I	1.254	1.00
370_K	374_V	1.245	1.00
201_R	205_N	1.245	1.00
224_V	317_G	1.242	1.00
120_L	154_Q	1.237	1.00
215_R	236_G	1.234	1.00
307_P	329_I	1.234	1.00
390_R	407_D	1.230	1.00
198_T	370_K	1.228	1.00
342_L	384_L	1.227	1.00
228_T	295_A	1.223	1.00
204_A	211_I	1.223	1.00
216_V	239_I	1.221	1.00
294_P	318_A	1.207	1.00
292_L	309_V	1.205	1.00
232_L	239_I	1.199	1.00
94_T	409_V	1.186	0.99
217_I	287_S	1.185	0.99
328_E	331_K	1.182	0.99
124_E	128_R	1.181	0.99
263_V	267_T	1.181	0.99
113_V	126_L	1.179	0.99
95_W	341_I	1.176	0.99
118_L	126_L	1.176	0.99
209_G	312_K	1.172	0.99
248_G	281_N	1.172	0.99
379_N	383_T	1.170	0.99
301_I	330_M	1.166	0.99
207_F	312_K	1.157	0.99
215_R	252_E	1.157	0.99
329_I	332_Q	1.155	0.99
260_A	264_V	1.151	0.99
60_W	112_R	1.151	0.99
62_S	83_Q	1.149	0.99
215_R	288_D	1.148	0.99
391_K	403_A	1.146	0.99
134_I	137_Y	1.143	0.99
240_I	289_C	1.139	0.99
58_I	112_R	1.138	0.99
215_R	290_D	1.136	0.99
200_A	293_I	1.136	0.99
281_N	285_L	1.129	0.99
95_W	409_V	1.125	0.99
194_L	231_F	1.124	0.99
46_Q	56_T	1.124	0.99
367_E	371_K	1.122	0.99
257_V	261_L	1.120	0.99
216_V	291_I	1.119	0.99
230_K	261_L	1.111	0.99
233_S	258_N	1.110	0.99
79_P	114_D	1.099	0.99
100_L	349_V	1.092	0.99
387_F	404_L	1.092	0.99
197_A	232_L	1.091	0.99
251_N	259_R	1.087	0.99
259_R	262_E	1.083	0.99
313_L	336_I	1.081	0.99
151_T	156_M	1.078	0.99
158_W	161_D	1.077	0.99
200_A	291_I	1.072	0.99
123_L	126_L	1.071	0.99
194_L	370_K	1.065	0.99
77_Y	151_T	1.057	0.99
281_N	284_L	1.055	0.99
259_R	273_Y	1.054	0.99
221_F	242_V	1.049	0.99
227_F	230_K	1.049	0.99
365_S	368_E	1.048	0.99
100_L	345_A	1.043	0.99
411_G	414_K	1.041	0.99
303_K	307_P	1.040	0.99
283_E	286_I	1.039	0.99
207_F	336_I	1.039	0.99
280_T	284_L	1.037	0.99
327_D	398_R	1.035	0.99
240_I	250_I	1.035	0.99
217_I	240_I	1.030	0.98
203_A	315_V	1.029	0.98
65_N	413_M	1.028	0.98
142_V	168_G	1.018	0.98
136_K	168_G	1.017	0.98
196_V	293_I	1.014	0.98
196_V	295_A	1.014	0.98
179_P	182_L	1.011	0.98
314_I	330_M	1.007	0.98
78_G	149_I	1.003	0.98
196_V	200_A	0.991	0.98
260_A	273_Y	0.982	0.98
122_E	126_L	0.976	0.98
226_F	261_L	0.973	0.98
229_A	239_I	0.970	0.98
129_K	162_E	0.970	0.98
80_N	85_E	0.969	0.98
268_G	272_N	0.968	0.98
365_S	375_D	0.957	0.98
75_V	130_Y	0.956	0.98
301_I	306_A	0.956	0.98
406_V	409_V	0.954	0.97
292_L	300_V	0.950	0.97
194_L	374_V	0.947	0.97
201_R	211_I	0.946	0.97
189_L	227_F	0.945	0.97
371_K	375_D	0.944	0.97
77_Y	127_S	0.943	0.97
228_T	232_L	0.938	0.97
282_E	286_I	0.933	0.97
67_A	409_V	0.933	0.97
387_F	403_A	0.932	0.97
49_S	57_F	0.932	0.97
293_I	315_V	0.931	0.97
196_V	228_T	0.931	0.97
348_V	351_S	0.931	0.97
129_K	133_L	0.927	0.97
251_N	273_Y	0.926	0.97
395_Q	399_T	0.926	0.97
200_A	313_L	0.921	0.97
156_M	159_F	0.919	0.97
206_K	386_D	0.919	0.97
101_L	376_R	0.917	0.97
84_D	87_I	0.917	0.97
263_V	273_Y	0.917	0.97
385_Y	389_K	0.916	0.97
371_K	374_V	0.915	0.97
233_S	257_V	0.912	0.97
303_K	326_A	0.908	0.97
309_V	314_I	0.898	0.96
391_K	395_Q	0.872	0.96
129_K	165_K	0.872	0.96
128_R	162_E	0.870	0.96
304_F	307_P	0.863	0.95
263_V	272_N	0.863	0.95
215_R	240_I	0.860	0.95
72_K	348_V	0.857	0.95
127_S	131_V	0.856	0.95
271_V	275_E	0.856	0.95
327_D	331_K	0.855	0.95
255_I	260_A	0.854	0.95
233_S	239_I	0.845	0.95
288_D	311_A	0.844	0.95
261_L	264_V	0.840	0.95
233_S	256_D	0.839	0.95
262_E	265_Q	0.838	0.95
48_R	55_R	0.836	0.95
386_D	389_K	0.834	0.95
162_E	166_I	0.832	0.94
77_Y	111_I	0.829	0.94
240_I	287_S	0.826	0.94
185_I	364_I	0.822	0.94
120_L	124_E	0.820	0.94
199_I	384_L	0.811	0.94
108_K	319_N	0.809	0.94
75_V	145_P	0.805	0.93
116_K	245_I	0.801	0.93
373_I	377_M	0.801	0.93
250_I	287_S	0.797	0.93
68_L	98_S	0.793	0.93
227_F	231_F	0.792	0.93
141_D	359_R	0.791	0.93
131_V	175_F	0.787	0.93
108_K	192_T	0.787	0.93
307_P	333_R	0.786	0.93
109_G	130_Y	0.784	0.93
301_I	314_I	0.783	0.92
160_L	170_V	0.783	0.92
120_L	123_L	0.780	0.92
394_D	399_T	0.776	0.92
351_S	354_E	0.774	0.92
244_D	247_G	0.766	0.92
128_R	161_D	0.766	0.92
269_S	272_N	0.765	0.92
90_S	94_T	0.765	0.92
232_L	293_I	0.762	0.91
249_V	270_V	0.760	0.91
301_I	340_D	0.758	0.91
249_V	260_A	0.755	0.91
314_I	322_L	0.755	0.91
267_T	270_V	0.754	0.91
211_I	216_V	0.754	0.91
120_L	126_L	0.754	0.91
207_F	313_L	0.751	0.91
263_V	268_G	0.751	0.91
244_D	264_V	0.750	0.91
109_G	127_S	0.749	0.91
131_V	162_E	0.748	0.91
388_H	395_Q	0.747	0.91
191_S	373_I	0.738	0.90
387_F	400_V	0.738	0.90
250_I	277_K	0.737	0.90
132_Q	166_I	0.737	0.90
133_L	136_K	0.734	0.90
231_F	370_K	0.734	0.90
166_I	175_F	0.732	0.90
226_F	265_Q	0.731	0.90
356_A	362_G	0.730	0.90
55_R	117_K	0.729	0.90
49_S	53_K	0.728	0.89
241_G	248_G	0.725	0.89
388_H	391_K	0.723	0.89
72_K	104_Y	0.721	0.89
192_T	347_G	0.721	0.89
96_K	319_N	0.719	0.89
150_N	224_V	0.718	0.89
311_A	314_I	0.712	0.88
244_D	269_S	0.711	0.88
291_I	313_L	0.708	0.88
270_V	273_Y	0.707	0.88
131_V	134_I	0.706	0.88
159_F	175_F	0.706	0.88
309_V	330_M	0.704	0.88
160_L	164_I	0.702	0.88
154_Q	157_A	0.702	0.88
238_K	253_N	0.701	0.88
380_A	384_L	0.701	0.88
381_F	384_L	0.700	0.88
388_H	397_L	0.700	0.88
267_T	272_N	0.697	0.87
345_A	349_V	0.692	0.87
279_V	287_S	0.688	0.87
336_I	397_L	0.688	0.87
405_A	409_V	0.687	0.87
372_L	375_D	0.687	0.87
199_I	315_V	0.684	0.86
50_S	125_D	0.684	0.86
218_I	242_V	0.684	0.86
140_S	169_K	0.683	0.86
167_T	171_D	0.683	0.86
248_G	286_I	0.683	0.86
311_A	335_V	0.682	0.86
263_V	274_L	0.680	0.86
47_I	57_F	0.680	0.86
391_K	394_D	0.679	0.86
197_A	231_F	0.679	0.86
378_I	382_N	0.676	0.86
81_V	110_G	0.674	0.86
156_M	182_L	0.674	0.86
376_R	379_N	0.673	0.85
264_V	278_K	0.673	0.85
193_G	228_T	0.672	0.85
322_L	326_A	0.672	0.85
350_G	364_I	0.671	0.85
114_D	119_T	0.671	0.85
229_A	257_V	0.668	0.85
330_M	337_V	0.668	0.85
101_L	379_N	0.666	0.85
337_V	340_D	0.665	0.85
349_V	353_V	0.665	0.85
322_L	337_V	0.664	0.85
224_V	245_I	0.664	0.85
293_I	317_G	0.663	0.85
260_A	263_V	0.662	0.85
387_F	390_R	0.660	0.84
303_K	327_D	0.659	0.84
349_V	377_M	0.659	0.84
92_I	320_G	0.656	0.84
385_Y	388_H	0.656	0.84
199_I	338_I	0.651	0.84
290_D	312_K	0.649	0.83
116_K	119_T	0.649	0.83
247_G	270_V	0.649	0.83
352_Y	356_A	0.646	0.83
406_V	410_V	0.642	0.83
357_N	364_I	0.641	0.83
283_E	305_N	0.640	0.83
67_A	413_M	0.639	0.82
138_L	159_F	0.638	0.82
63_Q	142_V	0.638	0.82
159_F	162_E	0.638	0.82
177_G	351_S	0.637	0.82
205_N	382_N	0.635	0.82
188_R	350_G	0.635	0.82
276_G	281_N	0.633	0.82
251_N	276_G	0.632	0.82
140_S	171_D	0.630	0.82
116_K	264_V	0.630	0.82
86_V	90_S	0.628	0.81
404_L	408_R	0.627	0.81
55_R	118_L	0.626	0.81
196_V	343_A	0.626	0.81
48_R	54_L	0.624	0.81
202_D	206_K	0.624	0.81
194_L	230_K	0.623	0.81
191_S	223_N	0.622	0.81
260_A	270_V	0.622	0.81
217_I	284_L	0.622	0.81
272_N	278_K	0.621	0.81
248_G	287_S	0.620	0.80
204_A	208_I	0.619	0.80
260_A	278_K	0.619	0.80
203_A	336_I	0.618	0.80
204_A	214_S	0.617	0.80
317_G	343_A	0.617	0.80
63_Q	71_Y	0.615	0.80
247_G	271_V	0.614	0.80
77_Y	113_V	0.611	0.80
67_A	412_A	0.606	0.79
197_A	228_T	0.606	0.79
203_A	385_Y	0.605	0.79
391_K	407_D	0.604	0.79
314_I	335_V	0.604	0.79
372_L	376_R	0.604	0.79
190_Y	227_F	0.603	0.79
302_N	322_L	0.603	0.79
188_R	223_N	0.603	0.79
338_I	397_L	0.602	0.79
205_N	378_I	0.600	0.78
68_L	408_R	0.599	0.78
327_D	330_M	0.599	0.78
219_Q	300_V	0.598	0.78
124_E	158_W	0.597	0.78
88_A	320_G	0.596	0.78
246_G	271_V	0.595	0.78
126_L	129_K	0.593	0.77
197_A	201_R	0.593	0.77
47_I	50_S	0.593	0.77
273_Y	276_G	0.592	0.77
86_V	110_G	0.591	0.77
221_F	260_A	0.591	0.77
229_A	260_A	0.591	0.77
286_I	305_N	0.591	0.77
387_F	395_Q	0.589	0.77
199_I	342_L	0.588	0.77
349_V	376_R	0.586	0.77
298_E	320_G	0.586	0.77
385_Y	397_L	0.585	0.77
147_P	223_N	0.582	0.76
302_N	323_T	0.582	0.76
91_M	95_W	0.581	0.76
403_A	406_V	0.581	0.76
208_I	214_S	0.581	0.76
292_L	314_I	0.580	0.76
398_R	402_M	0.580	0.76
127_S	159_F	0.579	0.76
118_L	122_E	0.577	0.76
96_K	108_K	0.577	0.76
82_T	112_R	0.577	0.76
228_T	317_G	0.576	0.75
282_E	304_F	0.576	0.75
370_K	377_M	0.575	0.75
327_D	337_V	0.575	0.75
185_I	350_G	0.574	0.75
204_A	209_G	0.574	0.75
147_P	188_R	0.573	0.75
258_N	261_L	0.572	0.75
307_P	332_Q	0.571	0.75
303_K	330_M	0.571	0.75
350_G	369_A	0.570	0.75
400_V	403_A	0.570	0.75
157_A	161_D	0.570	0.75
248_G	280_T	0.569	0.75
123_L	267_T	0.569	0.75
62_S	107_G	0.567	0.74
221_F	257_V	0.566	0.74
278_K	281_N	0.565	0.74
369_A	372_L	0.565	0.74
87_I	90_S	0.564	0.74
264_V	270_V	0.563	0.74
241_G	255_I	0.563	0.74
213_G	236_G	0.560	0.73
217_I	311_A	0.558	0.73
191_S	350_G	0.558	0.73
232_L	291_I	0.557	0.73
192_T	223_N	0.556	0.73
192_T	344_N	0.555	0.73
217_I	288_D	0.555	0.73
95_W	406_V	0.554	0.73
271_V	278_K	0.553	0.72
206_K	336_I	0.553	0.72
215_R	250_I	0.552	0.72
338_I	381_F	0.552	0.72
99_L	383_T	0.552	0.72
217_I	248_G	0.550	0.72
379_N	382_N	0.549	0.72
243_S	285_L	0.548	0.72
188_R	351_S	0.548	0.72
156_M	175_F	0.548	0.72
108_K	146_A	0.547	0.72
104_Y	355_W	0.546	0.72
203_A	381_F	0.545	0.71
151_T	191_S	0.544	0.71
79_P	115_P	0.544	0.71
383_T	386_D	0.541	0.71
388_H	394_D	0.541	0.71
154_Q	158_W	0.539	0.71
204_A	313_L	0.538	0.70
226_F	257_V	0.538	0.70
322_L	327_D	0.538	0.70
301_I	337_V	0.535	0.70
377_M	380_A	0.535	0.70
218_I	232_L	0.533	0.70
72_K	97_N	0.533	0.70
141_D	361_G	0.533	0.70
334_G	394_D	0.532	0.70
57_F	113_V	0.531	0.69
127_S	155_T	0.531	0.69
180_S	186_G	0.530	0.69
65_N	94_T	0.530	0.69
306_A	330_M	0.530	0.69
301_I	305_N	0.529	0.69
384_L	388_H	0.529	0.69
226_F	263_V	0.529	0.69
377_M	381_F	0.528	0.69
68_L	105_G	0.524	0.68
176_T	351_S	0.522	0.68
384_L	387_F	0.522	0.68
53_K	56_T	0.522	0.68
226_F	230_K	0.521	0.68
295_A	317_G	0.521	0.68
146_A	223_N	0.521	0.68
128_R	131_V	0.521	0.68
301_I	329_I	0.520	0.68
374_V	377_M	0.519	0.68
356_A	360_S	0.519	0.68
200_A	317_G	0.518	0.68
201_R	378_I	0.518	0.68
378_I	381_F	0.516	0.67
214_S	291_I	0.516	0.67
72_K	355_W	0.514	0.67
248_G	284_L	0.513	0.67
353_V	368_E	0.511	0.67
272_N	275_E	0.511	0.67
98_S	405_A	0.510	0.66
251_N	275_E	0.510	0.66
147_P	351_S	0.510	0.66
297_V	300_V	0.509	0.66
72_K	351_S	0.509	0.66
304_F	308_K	0.509	0.66
285_L	300_V	0.506	0.66
131_V	137_Y	0.505	0.66
314_I	326_A	0.504	0.65
193_G	317_G	0.503	0.65
231_F	234_E	0.502	0.65
259_R	263_V	0.502	0.65
125_D	161_D	0.502	0.65
251_N	255_I	0.501	0.65
193_G	224_V	0.500	0.65

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2yfqA	5	0.9332	100	0.07	Contact Map
4xgiA	6	0.9809	100	0.07	Contact Map
2tmgA	5	0.9714	100	0.084	Contact Map
1v9lA	4	0.9833	100	0.088	Contact Map
3aogA	8	0.9905	100	0.09	Contact Map
3aoeE	3	0.9833	100	0.092	Contact Map
3k92A	5	0.9881	100	0.093	Contact Map
3r3jA	5	0.9928	100	0.093	Contact Map
4fccA	5	0.9857	100	0.096	Contact Map
2bmaA	5	0.9928	100	0.097	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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