GREMLIN Database
Q97Y68 - Transposase, putative
UniProt: Q97Y68 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 133 (121)
Sequences: 1753 (1171)
Seq/√Len: 106.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_Y91_K4.7431.00
33_A126_W2.6531.00
40_L80_F2.6041.00
35_Y92_F2.5651.00
15_Y67_C2.3161.00
53_A123_E2.2951.00
39_V84_S2.1761.00
17_F77_A2.1191.00
40_L84_S2.0121.00
15_Y109_T1.9991.00
64_F122_I1.9301.00
49_C76_L1.9181.00
67_C73_P1.8821.00
17_F65_V1.8331.00
47_L79_Y1.7981.00
11_Y107_V1.7511.00
120_K124_E1.7471.00
20_I102_T1.6951.00
87_L90_K1.6751.00
35_Y38_E1.6701.00
89_L98_G1.6071.00
75_Y78_N1.5681.00
120_K123_E1.5551.00
86_R90_K1.5081.00
115_S119_K1.5031.00
20_I24_R1.4491.00
13_C67_C1.4441.00
35_Y39_V1.4221.00
85_A89_L1.3971.00
64_F115_S1.3671.00
36_T88_I1.3340.99
37_K41_K1.3320.99
44_A51_I1.3320.99
119_K123_E1.3310.99
65_V76_L1.3300.99
28_L36_T1.3280.99
43_I47_L1.3260.99
124_E127_R1.3190.99
48_G70_R1.3180.99
33_A37_K1.2930.99
28_L100_L1.2920.99
43_I83_K1.2600.99
73_P77_A1.2400.99
32_I94_Q1.2310.99
50_E66_N1.2200.99
68_P71_Y1.2120.99
13_C107_V1.2080.99
116_E119_K1.1950.99
15_Y73_P1.1940.99
41_K45_E1.1860.99
39_V83_K1.1770.99
44_A80_F1.1560.98
114_S117_V1.1550.98
67_C76_L1.1550.98
39_V87_L1.1390.98
110_A115_S1.1360.98
17_F73_P1.1180.98
73_P107_V1.1090.98
44_A49_C1.0780.98
14_N110_A1.0490.97
37_K56_V1.0280.97
15_Y107_V1.0120.96
44_A63_L1.0100.96
40_L54_L1.0030.96
72_A75_Y0.9990.96
42_S46_E0.9810.96
13_C73_P0.9670.95
53_A119_K0.9630.95
39_V43_I0.9590.95
11_Y66_N0.9490.95
16_H110_A0.9460.95
37_K55_E0.9430.95
56_V61_I0.9420.95
17_F107_V0.9360.95
74_S105_Y0.9350.94
14_N52_I0.9330.94
44_A76_L0.9200.94
71_Y76_L0.9150.94
79_Y82_G0.9070.94
111_G114_S0.9030.93
79_Y83_K0.9020.93
37_K54_L0.8810.93
69_P74_S0.8800.92
64_F110_A0.8710.92
12_L108_A0.8690.92
55_E126_W0.8620.92
32_I88_I0.8560.91
85_A98_G0.8500.91
40_L61_I0.8490.91
95_L98_G0.8460.91
40_L63_L0.8420.91
89_L99_K0.8410.91
14_N66_N0.8410.91
26_N59_D0.8410.91
117_V120_K0.8290.90
28_L88_I0.8140.89
19_W65_V0.8110.89
36_T40_L0.8010.88
49_C71_Y0.8000.88
30_N126_W0.7960.88
39_V42_S0.7890.88
43_I79_Y0.7850.87
38_E45_E0.7820.87
38_E88_I0.7730.87
65_V107_V0.7700.86
42_S45_E0.7650.86
31_E35_Y0.7640.86
29_V94_Q0.7640.86
33_A57_M0.7630.86
35_Y88_I0.7630.86
51_I65_V0.7580.86
85_A99_K0.7550.85
89_L96_N0.7480.85
9_T13_C0.7410.84
57_M126_W0.7300.83
12_L66_N0.7250.83
75_Y79_Y0.7170.82
38_E42_S0.7060.81
78_N103_R0.7060.81
72_A77_A0.7050.81
33_A55_E0.7030.81
65_V73_P0.7020.81
78_N82_G0.6920.80
33_A56_V0.6810.79
28_L32_I0.6770.79
44_A82_G0.6720.78
11_Y15_Y0.6560.76
88_I91_K0.6540.76
53_A61_I0.6340.74
28_L33_A0.6290.73
11_Y69_P0.6280.73
30_N34_E0.6250.73
122_I125_Q0.6210.72
41_K51_I0.6190.72
88_I95_L0.6180.72
68_P74_S0.6180.72
82_G89_L0.6150.72
14_N115_S0.6140.72
116_E120_K0.6140.72
37_K57_M0.6130.71
52_I66_N0.6110.71
33_A54_L0.6020.70
48_G96_N0.6020.70
16_H62_H0.5990.70
28_L56_V0.5940.69
38_E91_K0.5830.68
16_H60_H0.5820.67
47_L83_K0.5810.67
93_P96_N0.5800.67
34_E41_K0.5700.66
82_G85_A0.5690.66
45_E48_G0.5670.65
113_V118_I0.5610.65
13_C109_T0.5610.65
29_V33_A0.5550.64
42_S87_L0.5550.64
68_P72_A0.5540.64
40_L51_I0.5540.64
12_L122_I0.5530.64
65_V71_Y0.5490.63
24_R121_Y0.5490.63
7_R104_S0.5490.63
31_E94_Q0.5480.63
8_H103_R0.5480.63
44_A65_V0.5470.63
31_E34_E0.5400.62
34_E45_E0.5390.62
12_L106_F0.5380.61
82_G86_R0.5340.61
83_K87_L0.5310.60
32_I95_L0.5290.60
46_E83_K0.5290.60
10_K104_S0.5290.60
36_T105_Y0.5220.59
48_G75_Y0.5200.59
14_N64_F0.5180.59
93_P99_K0.5150.58
20_I55_E0.5150.58
57_M125_Q0.5150.58
108_A114_S0.5130.58
114_S122_I0.5090.57
71_Y109_T0.5000.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2f5gA 2 0.9774 100 0.316 Contact Map
2vjvA 2 0.9173 100 0.333 Contact Map
2fyxA 2 0.9398 100 0.375 Contact Map
4er8A 1 0.9398 99.9 0.493 Contact Map
4nrdA 3 0.5489 8.3 0.947 Contact Map
2x3gA 2 0.8346 7.8 0.947 Contact Map
4m8kA 2 0.5639 6.4 0.949 Contact Map
2kvvA 1 0.5038 5.3 0.951 Contact Map
2yxoA 3 0.5113 5 0.952 Contact Map
3i4sA 2 0.7744 3.9 0.954 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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