GREMLIN Database
Q97XZ4 - Orf in partial transposon ISC1904
UniProt: Q97XZ4 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 191 (182)
Sequences: 479 (332)
Seq/√Len: 24.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
60_A77_L4.2161.00
56_V116_R4.2091.00
81_V118_V3.6901.00
116_R143_E3.5111.00
7_V11_L2.7740.99
102_F125_L2.7610.99
58_L147_L2.7010.99
109_I137_C2.6150.99
13_I21_Y2.5880.99
90_D101_G2.4820.99
17_T21_Y2.4290.98
5_K9_Q2.3270.98
134_E138_K2.2550.97
18_L39_F2.1970.97
110_L140_H2.1220.96
16_P19_R2.1150.96
105_L114_V2.0740.96
2_L7_V2.0170.95
84_Y145_V2.0170.95
22_V37_W1.9990.95
130_F144_I1.9460.94
97_M131_E1.9080.93
58_L77_L1.8990.93
74_V87_V1.8780.93
95_L128_F1.8080.91
130_F146_V1.7710.90
137_C142_C1.7670.90
76_Y120_A1.7570.90
3_R34_S1.7390.89
16_P24_K1.7060.88
55_K108_M1.6990.88
88_I101_G1.6830.88
22_V29_P1.6380.86
118_V131_E1.6180.86
109_I114_V1.5960.85
58_L87_V1.5960.85
109_I117_V1.5950.85
126_V130_F1.5880.84
165_V176_S1.5820.84
108_M113_E1.5750.84
74_V89_T1.5590.83
26_Y33_Q1.5430.83
12_G141_G1.5340.82
97_M166_S1.5150.81
109_I119_I1.5080.81
4_P19_R1.4720.80
17_T20_E1.4540.79
71_V75_K1.4420.78
40_N43_D1.3790.75
118_V145_V1.3740.75
137_C171_L1.3630.74
31_I37_W1.3600.74
154_E158_E1.3560.74
62_V66_Q1.3280.72
95_L129_G1.3230.72
166_S169_E1.2980.70
14_S20_E1.2550.68
165_V169_E1.2530.67
20_E23_K1.2400.67
56_V143_E1.2380.66
66_Q69_E1.2280.66
27_I30_V1.2250.66
69_E72_N1.2030.64
7_V27_I1.2010.64
8_C13_I1.1950.64
121_Y158_E1.1940.64
120_A177_H1.1860.63
4_P18_L1.1740.62
106_L110_L1.1710.62
22_V39_F1.1490.61
90_D166_S1.1400.60
94_G125_L1.1390.60
7_V44_V1.1370.60
58_L81_V1.1220.59
88_I117_V1.1100.58
158_E169_E1.1060.58
169_E174_M1.1010.57
3_R38_R1.1000.57
57_V74_V1.0980.57
15_Y19_R1.0830.56
22_V27_I1.0740.55
130_F133_L1.0660.55
75_K78_E1.0530.54
56_V92_G1.0370.53
88_I105_L1.0310.52
62_V70_L1.0210.51
77_L147_L1.0170.51
163_V173_G1.0170.51
4_P29_P1.0070.50
63_S66_Q1.0020.50
116_R145_V0.9980.50
56_V118_V0.9940.50
8_C18_L0.9940.50
8_C15_Y0.9900.49
43_D46_K0.9740.48
81_V84_Y0.9690.48
28_K43_D0.9660.48
126_V133_L0.9620.47
90_D120_A0.9590.47
155_E167_F0.9540.47
27_I43_D0.9410.46
80_Q145_V0.9410.46
14_S171_L0.9320.45
57_V88_I0.9270.45
66_Q72_N0.9220.44
97_M126_V0.9140.44
165_V177_H0.9100.44
147_L153_E0.9020.43
13_I20_E0.9020.43
74_V106_L0.9000.43
172_H175_R0.8960.43
94_G102_F0.8910.42
117_V144_I0.8830.42
128_F159_D0.8820.42
3_R33_Q0.8770.41
109_I142_C0.8760.41
7_V18_L0.8700.41
90_D182_V0.8630.40
76_Y148_N0.8590.40
169_E176_S0.8590.40
160_L164_L0.8550.40
69_E120_A0.8480.39
11_L18_L0.8420.39
42_E72_N0.8400.39
137_C168_S0.8390.39
157_V160_L0.8370.38
26_Y34_S0.8360.38
2_L38_R0.8290.38
160_L173_G0.8200.37
5_K34_S0.8180.37
170_K174_M0.8150.37
6_E43_D0.8140.37
120_A165_V0.8110.37
19_R39_F0.7940.36
18_L22_V0.7920.35
4_P15_Y0.7920.35
19_R22_V0.7920.35
39_F43_D0.7890.35
71_V74_V0.7880.35
80_Q84_Y0.7860.35
154_E157_V0.7850.35
27_I133_L0.7800.35
54_R141_G0.7770.34
78_E87_V0.7700.34
72_N161_I0.7660.34
77_L142_C0.7660.34
7_V38_R0.7600.33
119_I144_I0.7590.33
92_G162_S0.7540.33
107_R139_A0.7500.33
83_E118_V0.7470.33
22_V31_I0.7270.31
6_E145_V0.7260.31
133_L137_C0.7210.31
39_F44_V0.7200.31
174_M181_K0.7150.31
64_S72_N0.7120.30
159_D173_G0.6990.30
8_C170_K0.6940.29
156_L165_V0.6890.29
2_L11_L0.6880.29
30_V38_R0.6800.28
96_N140_H0.6780.28
156_L159_D0.6780.28
100_K153_E0.6720.28
63_S127_R0.6720.28
4_P7_V0.6700.28
99_R126_V0.6690.28
48_M51_V0.6680.28
50_I75_K0.6670.28
160_L163_V0.6600.27
86_L99_R0.6580.27
44_V117_V0.6520.27
19_R36_K0.6510.27
128_F163_V0.6510.27
106_L145_V0.6500.27
177_H181_K0.6470.27
90_D144_I0.6460.27
152_K174_M0.6430.26
13_I16_P0.6380.26
118_V135_E0.6350.26
9_Q67_K0.6340.26
80_Q148_N0.6310.26
37_W44_V0.6290.26
117_V146_V0.6230.25
19_R37_W0.6220.25
160_L167_F0.6210.25
102_F126_V0.6210.25
159_D163_V0.6200.25
138_K170_K0.6200.25
134_E144_I0.6130.25
54_R142_C0.6120.25
15_Y37_W0.6120.25
14_S22_V0.6110.25
57_V114_V0.6100.25
33_Q112_N0.6100.25
50_I115_S0.6070.24
75_K79_E0.5990.24
168_S174_M0.5980.24
122_P164_L0.5980.24
57_V105_L0.5950.24
91_I99_R0.5950.24
110_L136_T0.5940.24
76_Y162_S0.5930.24
85_D118_V0.5920.24
128_F173_G0.5920.24
133_L156_L0.5910.24
31_I36_K0.5900.24
72_N75_K0.5900.24
134_E151_E0.5860.23
7_V84_Y0.5840.23
19_R31_I0.5840.23
4_P8_C0.5830.23
22_V32_L0.5830.23
136_T139_A0.5820.23
102_F166_S0.5820.23
98_K161_I0.5790.23
64_S173_G0.5760.23
10_R89_T0.5750.23
80_Q147_L0.5750.23
65_K120_A0.5720.23
54_R111_N0.5720.23
57_V149_Q0.5670.22
102_F115_S0.5670.22
156_L167_F0.5650.22
34_S112_N0.5620.22
98_K140_H0.5550.22
27_I52_K0.5550.22
8_C12_G0.5520.22
82_K105_L0.5520.22
126_V162_S0.5520.22
95_L132_I0.5500.22
55_K115_S0.5470.21
6_E32_L0.5450.21
56_V115_S0.5450.21
6_E156_L0.5450.21
12_G128_F0.5440.21
98_K170_K0.5420.21
8_C102_F0.5420.21
46_K121_Y0.5380.21
180_E183_K0.5380.21
76_Y177_H0.5370.21
6_E10_R0.5370.21
89_T136_T0.5340.21
45_E48_M0.5320.21
84_Y147_L0.5320.21
177_H183_K0.5310.21
100_K115_S0.5310.21
146_V164_L0.5290.20
122_P178_E0.5290.20
92_G143_E0.5280.20
63_S128_F0.5260.20
39_F168_S0.5260.20
4_P21_Y0.5250.20
114_V142_C0.5240.20
5_K8_C0.5220.20
76_Y90_D0.5180.20
23_K100_K0.5180.20
2_L13_I0.5170.20
129_G168_S0.5160.20
129_G145_V0.5160.20
176_S179_Y0.5160.20
23_K31_I0.5140.20
85_D147_L0.5130.20
10_R144_I0.5110.20
151_E164_L0.5090.20
90_D97_M0.5090.20
118_V180_E0.5080.20
117_V125_L0.5040.19
123_D127_R0.5030.19
30_V43_D0.5010.19
100_K164_L0.5010.19
118_V133_L0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ilxA 2 0.7173 99.9 0.657 Contact Map
3lhkA 2 0.7277 99.9 0.667 Contact Map
3g13A 2 0.7277 99.8 0.743 Contact Map
3bvpA 4 0.623 99.8 0.751 Contact Map
4bqqA 2 0.6963 99.7 0.752 Contact Map
2mhcA 1 0.5602 99.7 0.753 Contact Map
3guvA 2 0.6859 99.7 0.759 Contact Map
2gm5A 4 0.6178 99.7 0.766 Contact Map
1gdtA 2 0.6911 99.7 0.77 Contact Map
3pkzA 4 0.5864 99.7 0.771 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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