GREMLIN Database
Q97XY3 - Nitric oxide reductase, subunit I (Cytochrome B) (NorB-2)
UniProt: Q97XY3 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 194 (181)
Sequences: 417 (337)
Seq/√Len: 25.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
113_I121_W3.6621.00
46_E125_N3.6411.00
89_L93_V3.0611.00
43_V121_W3.0321.00
96_Q104_K2.8251.00
47_N125_N2.8020.99
123_V128_V2.7340.99
101_P105_V2.6890.99
139_C159_N2.4250.98
136_N140_N2.3980.98
115_D118_T2.3340.98
171_G175_F2.3020.98
45_T128_V2.2840.98
59_S163_N2.2300.97
69_L83_G2.2240.97
41_S119_S2.1920.97
41_S54_G2.1820.97
52_F166_A2.0590.96
143_Y161_L2.0100.95
56_E163_N1.9620.94
113_I177_Q1.8860.93
69_L86_F1.8830.93
45_T123_V1.8320.92
152_K155_L1.8010.91
95_N98_T1.7870.91
83_G86_F1.7720.91
76_W174_V1.7160.89
72_Y151_L1.7140.89
108_P124_S1.6930.89
144_N154_N1.6480.87
15_L70_F1.5780.85
43_V123_V1.5580.84
123_V131_Y1.5520.84
43_V51_L1.5150.82
67_Y142_L1.4890.81
17_A26_I1.4850.81
26_I63_L1.4620.80
157_S161_L1.4600.80
46_E122_V1.4580.80
45_T49_T1.4470.79
75_F160_D1.4280.78
42_V120_R1.4270.78
19_V23_V1.3990.77
115_D181_F1.3820.76
15_L74_S1.3820.76
70_F75_F1.3790.76
123_V169_L1.3730.75
90_A169_L1.3590.74
109_A176_H1.3560.74
8_D98_T1.3420.74
27_A80_G1.3420.74
97_T100_P1.3400.73
95_N107_G1.3320.73
176_H185_N1.3290.73
72_Y155_L1.3120.72
112_S142_L1.3110.72
63_L142_L1.2750.70
69_L150_G1.2560.68
80_G109_A1.2560.68
142_L164_I1.2430.68
117_E120_R1.2420.68
27_A172_A1.2250.66
145_N151_L1.2170.66
70_F171_G1.2160.66
43_V128_V1.2130.66
96_Q99_D1.1910.64
173_V186_I1.1900.64
42_V50_V1.1850.64
57_V65_Q1.1750.63
64_M127_Y1.1520.62
98_T105_V1.1520.62
64_M69_L1.1510.61
72_Y83_G1.1340.60
47_N119_S1.1300.60
64_M83_G1.1220.59
95_N103_I1.1210.59
100_P103_I1.1130.59
11_S150_G1.1060.58
49_T183_R1.1050.58
51_L123_V1.1050.58
122_V125_N1.1000.58
128_V132_N1.0950.58
51_L111_S1.0790.56
23_V28_L1.0490.54
17_A52_F1.0460.54
80_G168_I1.0440.54
65_Q70_F1.0420.54
51_L56_E1.0420.54
41_S51_L1.0380.53
44_E50_V1.0340.53
180_S185_N1.0310.53
94_I127_Y1.0270.53
83_G150_G1.0050.51
43_V116_S1.0010.51
26_I176_H1.0010.51
41_S120_R0.9960.50
10_W14_V0.9900.50
39_I53_T0.9810.49
112_S177_Q0.9770.49
64_M150_G0.9650.48
50_V122_V0.9640.48
64_M86_F0.9580.48
7_G80_G0.9570.48
52_F181_F0.9510.47
89_L138_L0.9460.47
59_S175_F0.9340.46
56_E162_R0.9300.46
63_L156_V0.9210.45
8_D30_G0.9130.44
113_I124_S0.9020.44
17_A61_K0.9020.44
140_N145_N0.9010.44
29_A64_M0.8990.43
54_G58_I0.8910.43
152_K161_L0.8870.43
21_V82_Y0.8830.42
139_C165_T0.8790.42
84_T112_S0.8720.42
108_P126_N0.8630.41
87_T117_E0.8610.41
33_L36_L0.8570.40
76_W87_T0.8560.40
20_L54_G0.8550.40
69_L72_Y0.8520.40
98_T101_P0.8510.40
76_W86_F0.8490.40
55_G59_S0.8400.39
164_I168_I0.8390.39
40_P53_T0.8380.39
50_V126_N0.8360.39
111_S185_N0.8360.39
66_K83_G0.8320.39
90_A94_I0.8250.38
114_T118_T0.8040.37
53_T131_Y0.7990.36
121_W176_H0.7970.36
95_N175_F0.7960.36
51_L159_N0.7920.36
86_F150_G0.7900.36
103_I107_G0.7890.36
72_Y161_L0.7870.36
61_K78_F0.7860.36
46_E119_S0.7850.36
64_M70_F0.7840.35
25_Y32_T0.7830.35
30_G162_R0.7730.35
101_P104_K0.7720.35
61_K173_V0.7700.35
76_W112_S0.7680.34
78_F173_V0.7660.34
44_E120_R0.7520.33
71_D178_I0.7520.33
66_K94_I0.7510.33
68_G78_F0.7450.33
48_G124_S0.7430.33
94_I146_S0.7410.33
170_W173_V0.7390.33
32_T86_F0.7260.32
43_V52_F0.7240.32
159_N162_R0.7210.31
39_I57_V0.7150.31
108_P172_A0.7150.31
59_S62_V0.7030.30
29_A169_L0.7030.30
84_T92_K0.7000.30
64_M94_I0.6990.30
62_V75_F0.6970.30
61_K156_V0.6950.30
81_Y85_D0.6930.30
140_N162_R0.6930.30
133_T147_S0.6920.30
52_F56_E0.6900.29
15_L185_N0.6870.29
136_N139_C0.6870.29
51_L181_F0.6870.29
29_A32_T0.6860.29
129_K132_N0.6860.29
153_P157_S0.6840.29
20_L24_V0.6800.29
89_L110_Y0.6800.29
14_V134_L0.6750.29
45_T122_V0.6730.28
39_I61_K0.6730.28
55_G134_L0.6700.28
127_Y150_G0.6680.28
54_G104_K0.6650.28
20_L144_N0.6630.28
112_S121_W0.6620.28
37_P76_W0.6620.28
63_L124_S0.6590.28
75_F78_F0.6580.28
61_K121_W0.6530.27
163_N166_A0.6480.27
47_N132_N0.6480.27
153_P177_Q0.6430.27
14_V93_V0.6420.27
162_R165_T0.6420.27
22_Y78_F0.6420.27
90_A131_Y0.6400.27
35_H165_T0.6380.26
49_T132_N0.6350.26
99_D158_P0.6340.26
64_M90_A0.6340.26
72_Y87_T0.6310.26
29_A92_K0.6300.26
97_T115_D0.6260.26
42_V129_K0.6240.26
94_I110_Y0.6240.26
51_L148_N0.6220.26
55_G118_T0.6220.26
119_S183_R0.6190.25
114_T119_S0.6170.25
39_I59_S0.6150.25
33_L61_K0.6130.25
100_P181_F0.6080.25
90_A101_P0.6070.25
19_V148_N0.6060.25
96_Q107_G0.6010.24
76_W92_K0.6000.24
133_T136_N0.5980.24
80_G148_N0.5970.24
151_L155_L0.5970.24
107_G136_N0.5930.24
66_K174_V0.5930.24
151_L161_L0.5900.24
116_S133_T0.5880.24
19_V30_G0.5870.24
95_N122_V0.5860.24
15_L183_R0.5770.23
59_S160_D0.5770.23
64_M146_S0.5760.23
31_Y35_H0.5670.23
65_Q184_Y0.5670.23
37_P174_V0.5650.23
131_Y135_Y0.5620.22
86_F94_I0.5610.22
76_W115_D0.5600.22
134_L137_E0.5560.22
108_P181_F0.5560.22
122_V129_K0.5530.22
66_K69_L0.5530.22
25_Y89_L0.5520.22
87_T139_C0.5510.22
177_Q185_N0.5500.22
66_K86_F0.5470.22
7_G109_A0.5450.22
35_H59_S0.5430.21
25_Y29_A0.5430.21
28_L185_N0.5420.21
67_Y89_L0.5410.21
27_A154_N0.5410.21
17_A156_V0.5390.21
124_S131_Y0.5390.21
107_G111_S0.5340.21
167_F171_G0.5330.21
69_L94_I0.5280.21
67_Y171_G0.5240.21
148_N171_G0.5220.20
20_L49_T0.5190.20
78_F83_G0.5180.20
82_Y109_A0.5110.20
96_Q100_P0.5090.20
139_C162_R0.5070.20
132_N136_N0.5070.20
116_S120_R0.5050.20
116_S132_N0.5050.20
142_L168_I0.5050.20
9_V138_L0.5050.20
110_Y146_S0.5010.19
116_S128_V0.5010.19
7_G21_V0.5000.19
83_G94_I0.5000.19
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3ayfA 2 0.9742 100 0.139 Contact Map
3wfdC 1 0.732 98 0.893 Contact Map
4pj0V 1 0.6907 87.4 0.939 Contact Map
3mk7B 1 0.7629 76.6 0.946 Contact Map
2bn5A 1 0.1289 53.6 0.954 Contact Map
4xxlA 1 0.4433 52.4 0.954 Contact Map
4pwaA 3 0.4175 51.3 0.955 Contact Map
3oa8A 1 0.5619 41.8 0.957 Contact Map
4j20A 1 0.4227 38.4 0.958 Contact Map
3hq9A 2 0.7784 37.1 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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