GREMLIN Database
Q97XS1 - Penicillin acylase
UniProt: Q97XS1 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 829 (744)
Sequences: 1593 (1200)
Seq/√Len: 44.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
476_H530_D9.2681.00
451_S454_D5.5181.00
798_F801_N5.4111.00
380_I387_Y4.7171.00
382_N385_Q4.6721.00
569_Y584_L4.5941.00
72_A78_L4.5791.00
631_E634_P4.1551.00
577_N580_D4.0311.00
319_N365_G4.0051.00
385_Q394_Q3.9921.00
308_S311_S3.9911.00
148_E152_Q3.7551.00
334_L347_S3.6041.00
393_Y413_N3.6011.00
678_Q685_W3.5731.00
137_K141_P3.5251.00
312_T577_N3.4561.00
389_N512_T3.3921.00
104_N178_Y3.3081.00
106_S113_A3.2421.00
316_I581_M3.1291.00
565_D587_N3.0971.00
805_L810_K3.0691.00
414_N515_E3.0271.00
62_I88_S3.0101.00
78_L336_L3.0011.00
89_Q332_I2.9351.00
473_S476_H2.9261.00
84_Y160_T2.8571.00
681_P684_I2.8151.00
478_G529_F2.8061.00
459_A469_L2.7971.00
379_E414_N2.7711.00
586_S809_F2.7701.00
710_G716_W2.6001.00
476_H529_F2.5991.00
104_N107_S2.5891.00
343_V354_V2.5081.00
565_D569_Y2.4941.00
568_H594_S2.4821.00
508_N514_Y2.4301.00
86_E150_F2.3901.00
94_I154_V2.3841.00
308_S315_P2.3731.00
60_I85_Y2.3471.00
399_N406_T2.3331.00
681_P686_V2.3301.00
678_Q686_V2.3171.00
308_S313_Q2.2661.00
159_N179_Y2.2621.00
305_V536_A2.2591.00
71_Y337_I2.2491.00
347_S354_V2.2281.00
385_Q392_W2.2041.00
689_N692_N2.2041.00
91_L167_P2.2031.00
678_Q684_I2.2001.00
91_L158_I2.1961.00
445_L461_Y2.1861.00
303_S470_A2.1761.00
388_Y391_K2.1701.00
397_E408_T2.1651.00
566_I749_L2.1611.00
306_I570_L2.1571.00
678_Q681_P2.1451.00
679_Y684_I2.1351.00
70_I85_Y2.0930.99
681_P685_W2.0570.99
80_L152_Q2.0560.99
679_Y685_W2.0490.99
470_A536_A2.0450.99
377_Y515_E2.0420.99
537_F563_A2.0350.99
682_T685_W2.0270.99
331_W770_S2.0050.99
303_S538_A1.9980.99
395_M417_L1.9730.99
643_E704_L1.9680.99
717_Y720_R1.9590.99
669_I674_I1.9570.99
629_Q743_F1.9480.99
124_G127_Q1.9450.99
375_D488_I1.9370.99
121_H400_Y1.9310.99
147_L185_S1.9210.99
477_A536_A1.9200.99
680_D684_I1.9120.99
450_T454_D1.9120.99
325_L768_G1.9020.99
82_E334_L1.8950.99
363_A777_P1.8900.99
480_I527_Q1.8810.99
651_K688_G1.8800.99
429_Y435_E1.8680.99
613_Q699_V1.8680.99
669_I673_F1.8630.99
214_N217_E1.8540.99
133_A144_Y1.8510.99
387_Y392_W1.8500.99
368_T467_Q1.8460.99
619_Y633_A1.8460.99
455_L471_I1.8450.99
698_F702_I1.8380.99
203_E372_S1.8220.98
99_L108_W1.8050.98
573_Q576_V1.7980.98
76_H145_S1.7910.98
69_H335_Q1.7810.98
512_T515_E1.7810.98
683_S686_V1.7700.98
682_T686_V1.7650.98
573_Q580_D1.7610.98
147_L151_S1.7430.98
541_Q563_A1.7370.98
70_I334_L1.7250.98
95_E175_V1.7240.98
317_L472_V1.7150.98
582_M811_Y1.7150.98
528_T533_R1.7120.98
151_S185_S1.7050.98
398_Y411_Y1.7040.98
56_G73_N1.7020.98
372_S375_D1.7020.98
58_V81_A1.6980.98
680_D685_W1.6900.98
369_P466_P1.6900.98
369_P481_V1.6890.98
579_S583_K1.6870.97
745_D748_T1.6710.97
61_Y71_Y1.6700.97
457_N460_K1.6610.97
215_Y219_N1.6580.97
678_Q682_T1.6450.97
169_E728_N1.6440.97
234_T237_P1.6270.97
377_Y429_Y1.6160.97
452_F471_I1.6110.97
92_F109_V1.6010.97
684_I687_N1.5910.96
386_Y395_M1.5880.96
335_Q342_N1.5850.96
166_L177_P1.5750.96
744_G751_V1.5720.96
678_Q687_N1.5710.96
362_T471_I1.5550.96
452_F529_F1.5510.96
399_N408_T1.5510.96
361_Y450_T1.5500.96
744_G748_T1.5490.96
647_N700_K1.5450.96
744_G749_L1.5440.96
395_M412_T1.5420.96
114_L407_Y1.5340.96
109_V113_A1.5340.96
735_L744_G1.5330.96
151_S182_P1.5320.96
107_S403_M1.5280.95
678_Q683_S1.5270.95
535_F567_Y1.5230.95
750_A769_S1.5210.95
643_E700_K1.5120.95
773_F814_Y1.5070.95
306_I581_M1.5040.95
91_L170_F1.5040.95
318_A585_Q1.4990.95
674_I678_Q1.4990.95
576_V580_D1.4970.95
342_N360_A1.4960.95
361_Y474_K1.4940.95
616_A636_I1.4920.95
744_G752_G1.4880.95
54_L58_V1.4870.95
80_L156_D1.4770.95
414_N509_G1.4760.95
588_V743_F1.4740.94
302_N367_T1.4730.94
366_L469_L1.4600.94
106_S111_A1.4530.94
62_I89_Q1.4460.94
74_N78_L1.4420.94
484_L519_Y1.4410.94
452_F455_L1.4400.94
130_I134_Q1.4350.94
85_Y88_S1.4240.93
55_S74_N1.4220.93
507_L514_Y1.4190.93
731_G736_S1.4160.93
381_V395_M1.4150.93
460_K523_K1.4150.93
652_I688_G1.4120.93
647_N697_S1.4080.93
380_I510_T1.4060.93
82_E86_E1.4060.93
196_L467_Q1.4000.93
677_A685_W1.3940.93
38_S795_V1.3910.93
396_N411_Y1.3810.92
582_M783_Y1.3770.92
745_D751_V1.3650.92
417_L425_G1.3640.92
313_Q776_S1.3640.92
133_A148_E1.3570.92
196_L323_L1.3540.92
108_W175_V1.3460.91
82_E353_G1.3460.91
635_T721_V1.3350.91
679_Y683_S1.3260.91
207_A506_P1.3240.91
333_P784_G1.3240.91
646_N650_A1.3240.91
95_E170_F1.3230.91
616_A702_I1.3220.91
78_L82_E1.3160.90
506_P516_P1.3140.90
76_H80_L1.3120.90
632_V635_T1.3100.90
639_Y705_L1.3090.90
745_D752_G1.3050.90
681_P687_N1.3050.90
323_L467_Q1.3010.90
386_Y393_Y1.3010.90
148_E182_P1.2940.90
600_I640_I1.2920.90
601_I621_R1.2840.89
679_Y686_V1.2810.89
199_G203_E1.2790.89
676_I684_I1.2770.89
78_L338_A1.2750.89
71_Y818_N1.2720.89
520_I550_F1.2720.89
51_I80_L1.2700.89
593_A597_T1.2680.89
130_I183_D1.2660.89
62_I85_Y1.2660.89
680_D687_N1.2650.88
76_H149_A1.2640.88
489_N495_G1.2620.88
735_L751_V1.2620.88
410_Y420_R1.2590.88
578_I774_I1.2570.88
60_I81_A1.2570.88
49_V84_Y1.2540.88
676_I685_W1.2330.87
712_N715_Q1.2250.87
379_E412_T1.2210.87
42_V796_S1.2210.87
589_T594_S1.2200.87
470_A538_A1.2190.87
429_Y515_E1.2180.87
684_I688_G1.2170.86
101_A187_A1.2020.86
653_L661_L1.2010.86
620_L633_A1.1980.86
382_N392_W1.1970.86
372_S488_I1.1960.85
337_I342_N1.1960.85
388_Y515_E1.1920.85
462_W467_Q1.1910.85
584_L749_L1.1870.85
108_W170_F1.1870.85
805_L812_I1.1860.85
539_P566_I1.1840.85
95_E99_L1.1830.85
323_L331_W1.1810.85
569_Y572_Y1.1810.85
679_Y682_T1.1800.85
414_N427_S1.1760.85
490_E495_G1.1740.84
144_Y148_E1.1730.84
569_Y573_Q1.1720.84
145_S149_A1.1700.84
395_M410_Y1.1700.84
412_T427_S1.1700.84
115_S118_I1.1610.84
804_P808_S1.1600.84
472_V477_A1.1570.84
453_N529_F1.1560.83
118_I407_Y1.1550.83
300_A368_T1.1530.83
671_P675_Y1.1490.83
565_D568_H1.1460.83
358_H816_G1.1440.83
313_Q577_N1.1430.83
346_W784_G1.1420.83
143_I441_I1.1360.82
619_Y622_N1.1350.82
386_Y412_T1.1340.82
170_F175_V1.1320.82
28_I32_F1.1310.82
668_Y671_P1.1230.82
770_S787_P1.1180.81
624_N628_Y1.1160.81
618_N621_R1.1160.81
597_T625_F1.1150.81
307_T310_F1.1130.81
688_G692_N1.1090.81
712_N716_W1.1080.81
619_Y632_V1.1040.81
738_G744_G1.1010.80
311_S315_P1.1000.80
665_S669_I1.0990.80
677_A684_I1.0930.80
109_V173_L1.0860.79
92_F96_L1.0840.79
388_Y393_Y1.0840.79
322_H367_T1.0830.79
594_S625_F1.0820.79
680_D683_S1.0820.79
85_Y89_Q1.0710.78
192_M467_Q1.0690.78
333_P802_Q1.0690.78
776_S782_F1.0660.78
74_N77_D1.0650.78
379_E417_L1.0640.78
688_G693_L1.0590.78
669_I678_Q1.0580.78
383_G392_W1.0570.78
386_Y413_N1.0510.77
151_S154_V1.0500.77
617_F621_R1.0490.77
66_G89_Q1.0460.77
749_L752_G1.0410.76
680_D686_V1.0410.76
358_H782_F1.0410.76
302_N322_H1.0390.76
306_I311_S1.0380.76
321_P356_I1.0340.76
748_T752_G1.0330.76
127_Q398_Y1.0320.76
590_D627_F1.0320.76
335_Q344_T1.0310.76
92_F173_L1.0290.76
456_I480_I1.0290.76
666_I670_V1.0270.75
366_L465_P1.0260.75
705_L709_L1.0260.75
709_L721_V1.0230.75
679_Y687_N1.0200.75
214_N218_I1.0170.75
54_L77_D1.0150.75
804_P807_L1.0150.75
334_L354_V1.0110.74
304_W566_I1.0090.74
676_I679_Y1.0090.74
735_L752_G1.0090.74
300_A430_W1.0080.74
362_T455_L1.0070.74
346_W771_L1.0060.74
692_N696_Q0.9960.73
677_A686_V0.9950.73
79_F341_F0.9950.73
593_A637_Y0.9950.73
485_Y525_L0.9940.73
59_N71_Y0.9920.73
59_N818_N0.9920.73
675_Y678_Q0.9890.73
32_F36_W0.9890.73
554_G557_W0.9810.72
70_I78_L0.9790.72
721_V763_P0.9780.72
65_N805_L0.9770.72
392_W799_R0.9760.72
531_P534_G0.9710.71
133_A186_L0.9700.71
22_F26_L0.9660.71
375_D516_P0.9610.70
51_I54_L0.9610.70
233_L237_P0.9560.70
680_D688_G0.9540.70
379_E427_S0.9540.70
29_L32_F0.9530.70
75_L448_N0.9460.69
92_F729_P0.9460.69
312_T575_S0.9450.69
310_F576_V0.9450.69
310_F535_F0.9450.69
157_Y161_L0.9430.69
446_L455_L0.9430.69
486_P516_P0.9410.69
75_L338_A0.9390.69
570_L584_L0.9370.69
590_D745_D0.9340.68
503_A516_P0.9330.68
783_Y811_Y0.9310.68
200_F204_L0.9300.68
180_W185_S0.9280.68
355_L366_L0.9280.68
451_S707_Q0.9280.68
99_L170_F0.9230.67
41_N795_V0.9220.67
362_T452_F0.9220.67
676_I680_D0.9200.67
146_Y444_L0.9190.67
401_T406_T0.9180.67
203_E506_P0.9170.67
193_G432_A0.9170.67
195_S467_Q0.9130.66
25_S29_L0.9120.66
351_I355_L0.9110.66
27_S30_N0.9100.66
566_I570_L0.9100.66
67_I812_I0.9090.66
785_I812_I0.9090.66
318_A774_I0.9080.66
452_F478_G0.9060.66
535_F571_E0.9050.66
308_S314_G0.9050.66
588_V626_T0.9050.66
114_L118_I0.9040.66
386_Y392_W0.9040.66
320_D772_R0.9030.66
452_F476_H0.9030.66
123_I428_L0.9010.65
137_K143_I0.9010.65
576_V581_M0.8990.65
643_E646_N0.8980.65
60_I67_I0.8980.65
87_A157_Y0.8970.65
301_S540_N0.8960.65
86_E347_S0.8940.65
677_A683_S0.8910.65
329_S786_F0.8900.64
378_L506_P0.8870.64
533_R536_A0.8870.64
383_G395_M0.8830.64
669_I685_W0.8820.64
460_K480_I0.8810.64
569_Y749_L0.8800.64
41_N793_S0.8800.64
742_I765_V0.8800.64
597_T620_L0.8790.64
381_V392_W0.8780.63
147_L182_P0.8780.63
28_I33_L0.8780.63
576_V584_L0.8770.63
158_I170_F0.8770.63
366_L538_A0.8760.63
336_L343_V0.8740.63
477_A531_P0.8740.63
161_L167_P0.8720.63
509_G515_E0.8710.63
92_F169_E0.8700.63
330_V467_Q0.8690.63
23_T27_S0.8690.63
745_D749_L0.8680.63
713_I716_W0.8680.63
371_G481_V0.8670.62
323_L368_T0.8670.62
612_I703_S0.8660.62
65_N812_I0.8660.62
738_G751_V0.8610.62
744_G763_P0.8610.62
285_A288_N0.8600.62
315_P472_V0.8590.62
126_P130_I0.8580.62
380_I424_Y0.8570.62
774_I811_Y0.8530.61
381_V425_G0.8520.61
456_I527_Q0.8510.61
613_Q698_F0.8510.61
650_A655_K0.8510.61
127_Q186_L0.8500.61
488_I516_P0.8500.61
99_L107_S0.8490.61
45_L798_F0.8480.61
690_F736_S0.8470.61
507_L515_E0.8440.60
738_G749_L0.8440.60
195_S368_T0.8430.60
310_F534_G0.8410.60
362_T451_S0.8400.60
508_N511_V0.8380.60
567_Y571_E0.8380.60
654_N658_L0.8370.60
785_I805_L0.8370.60
614_G618_N0.8370.60
639_Y701_A0.8370.60
321_P771_L0.8350.60
366_L443_I0.8350.60
154_V351_I0.8340.59
79_F146_Y0.8340.59
375_D503_A0.8330.59
24_T34_G0.8320.59
569_Y587_N0.8310.59
693_L697_S0.8300.59
616_A633_A0.8300.59
589_T626_T0.8290.59
359_T362_T0.8270.59
791_S796_S0.8270.59
605_V621_R0.8270.59
323_L367_T0.8270.59
232_N236_I0.8260.59
320_D539_P0.8260.59
233_L236_I0.8260.59
640_I702_I0.8230.58
211_T408_T0.8220.58
216_S221_I0.8210.58
311_S581_M0.8180.58
667_P671_P0.8180.58
303_S467_Q0.8170.58
344_T814_Y0.8130.57
154_V185_S0.8130.57
147_L186_L0.8130.57
311_S575_S0.8130.57
748_T751_V0.8110.57
388_Y413_N0.8110.57
774_I783_Y0.8080.57
98_G184_Y0.8060.57
135_Y404_G0.8030.57
728_N768_G0.8020.56
114_L402_L0.8020.56
518_G710_G0.7990.56
644_M694_V0.7980.56
704_L708_N0.7940.56
735_L794_L0.7920.55
82_E347_S0.7920.55
740_I803_L0.7920.55
651_K693_L0.7900.55
439_T462_W0.7890.55
438_L461_Y0.7870.55
616_A698_F0.7870.55
683_S687_N0.7870.55
210_Y505_T0.7860.55
304_W581_M0.7860.55
568_H589_T0.7850.55
379_E509_G0.7850.55
206_S556_F0.7840.55
322_H540_N0.7840.55
666_I669_I0.7830.55
107_S180_W0.7830.55
669_I677_A0.7820.55
451_S473_S0.7810.54
780_S817_Y0.7810.54
55_S76_H0.7800.54
182_P470_A0.7790.54
92_F728_N0.7770.54
97_F188_F0.7770.54
387_Y390_G0.7770.54
113_A116_S0.7760.54
647_N696_Q0.7760.54
376_A428_L0.7740.54
69_H337_I0.7730.54
506_P510_T0.7720.54
397_E410_Y0.7720.54
300_A752_G0.7710.53
303_S369_P0.7710.53
459_A482_A0.7700.53
28_I31_P0.7700.53
196_L432_A0.7690.53
469_L482_A0.7690.53
356_I366_L0.7670.53
776_S780_S0.7660.53
367_T540_N0.7660.53
634_P721_V0.7650.53
666_I674_I0.7630.53
485_Y553_I0.7620.53
521_P524_Y0.7610.53
87_A158_I0.7610.53
578_I783_Y0.7610.53
366_L770_S0.7610.53
42_V795_V0.7600.52
133_A182_P0.7600.52
106_S114_L0.7590.52
89_Q786_F0.7590.52
735_L738_G0.7580.52
404_G409_V0.7570.52
33_L37_Y0.7540.52
590_D748_T0.7530.52
275_F689_N0.7530.52
471_I476_H0.7520.52
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367_T468_N0.7380.50
391_K394_Q0.7380.50
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241_T244_G0.7300.50
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301_S367_T0.6910.46
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366_L467_Q0.6870.45
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604_M617_F0.6860.45
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768_G787_P0.6850.45
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172_L735_L0.6620.43
29_L33_L0.6620.43
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374_S428_L0.6600.43
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36_W39_S0.6590.43
242_V245_Y0.6570.43
456_I522_F0.6570.43
360_A816_G0.6560.42
736_S744_G0.6550.42
751_V763_P0.6550.42
487_L518_G0.6540.42
489_N517_I0.6540.42
390_G509_G0.6530.42
742_I807_L0.6530.42
180_W806_W0.6520.42
106_S354_V0.6500.42
744_G747_H0.6480.42
377_Y509_G0.6480.42
451_S529_F0.6480.42
124_G398_Y0.6470.42
108_W136_L0.6470.42
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320_D585_Q0.6460.42
74_N448_N0.6450.41
82_E354_V0.6430.41
127_Q131_M0.6430.41
523_K676_I0.6430.41
465_P768_G0.6410.41
701_A705_L0.6410.41
785_I802_Q0.6410.41
133_A183_D0.6410.41
91_L157_Y0.6410.41
601_I617_F0.6400.41
533_R567_Y0.6390.41
805_L808_S0.6380.41
388_Y512_T0.6380.41
442_S462_W0.6380.41
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321_P593_A0.6360.41
781_Q813_S0.6360.41
275_F282_M0.6350.41
645_V648_S0.6350.41
504_R555_G0.6340.40
359_T468_N0.6330.40
237_P241_T0.6330.40
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313_Q777_P0.6320.40
427_S512_T0.6320.40
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678_Q688_G0.6310.40
82_E336_L0.6310.40
462_W482_A0.6300.40
371_G412_T0.6270.40
303_S731_G0.6260.40
93_E349_V0.6250.40
216_S703_S0.6250.40
60_I64_S0.6240.40
158_I177_P0.6240.40
743_F751_V0.6240.40
738_G748_T0.6240.40
188_F416_P0.6230.39
643_E701_A0.6220.39
379_E510_T0.6220.39
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438_L441_I0.6200.39
321_P770_S0.6200.39
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584_L809_F0.6180.39
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26_L33_L0.6120.38
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453_N618_N0.6120.38
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566_I569_Y0.6120.38
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639_Y704_L0.6110.38
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301_S322_H0.6070.38
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219_N311_S0.6060.38
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467_Q806_W0.6050.38
597_T600_I0.6050.38
368_T430_W0.6040.38
736_S749_L0.6020.37
786_F802_Q0.6020.37
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84_Y157_Y0.6010.37
443_I466_P0.6010.37
307_T315_P0.6000.37
24_T29_L0.6000.37
216_S457_N0.6000.37
191_Y195_S0.6000.37
318_A322_H0.6000.37
722_H776_S0.5990.37
643_E697_S0.5990.37
672_D676_I0.5990.37
386_Y509_G0.5980.37
458_A472_V0.5970.37
174_N405_R0.5960.37
802_Q805_L0.5960.37
753_S767_I0.5950.37
391_K413_N0.5950.37
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333_P771_L0.5950.37
89_Q798_F0.5950.37
152_Q453_N0.5940.37
333_P346_W0.5940.37
387_Y698_F0.5930.37
427_S507_L0.5930.37
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579_S783_Y0.5920.37
670_V674_I0.5920.37
579_S582_M0.5920.37
413_N428_L0.5920.37
309_D571_E0.5910.37
598_P637_Y0.5900.36
442_S463_V0.5900.36
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771_L784_G0.5890.36
441_I461_Y0.5870.36
792_E799_R0.5860.36
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31_P34_G0.5800.36
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328_P792_E0.5790.35
600_I641_V0.5790.35
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448_N620_L0.5570.34
331_W366_L0.5570.34
241_T245_Y0.5560.33
385_Q395_M0.5560.33
399_N412_T0.5550.33
196_L368_T0.5540.33
336_L644_M0.5540.33
612_I616_A0.5540.33
53_G701_A0.5540.33
103_G117_D0.5530.33
63_D84_Y0.5530.33
414_N716_W0.5530.33
304_W322_H0.5520.33
532_V707_Q0.5520.33
216_S316_I0.5520.33
136_L584_L0.5510.33
679_Y688_G0.5510.33
204_L639_Y0.5510.33
737_V740_I0.5500.33
348_L430_W0.5500.33
368_T541_Q0.5490.33
323_L788_G0.5490.33
398_Y409_V0.5480.33
115_S517_I0.5480.33
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120_M194_W0.5470.33
592_W747_H0.5470.33
389_N511_V0.5460.33
539_P749_L0.5460.33
726_I787_P0.5460.33
468_N479_I0.5460.33
374_S508_N0.5460.33
29_L114_L0.5450.33
63_D69_H0.5450.33
195_S355_L0.5450.33
180_W354_V0.5450.33
736_S739_P0.5440.32
354_V364_W0.5440.32
603_A774_I0.5440.32
57_N703_S0.5440.32
506_P514_Y0.5440.32
773_F784_G0.5440.32
725_E739_P0.5430.32
192_M355_L0.5430.32
234_T809_F0.5430.32
318_A539_P0.5420.32
445_L457_N0.5420.32
330_V368_T0.5420.32
123_I175_V0.5410.32
35_I42_V0.5400.32
450_T618_N0.5400.32
723_F739_P0.5400.32
102_M192_M0.5400.32
358_H542_P0.5390.32
452_F473_S0.5390.32
48_I818_N0.5390.32
206_S557_W0.5390.32
626_T697_S0.5380.32
359_T455_L0.5380.32
696_Q700_K0.5380.32
97_F440_V0.5370.32
386_Y518_G0.5370.32
311_S418_V0.5370.32
726_I788_G0.5360.32
97_F382_N0.5360.32
362_T426_I0.5360.32
513_K692_N0.5360.32
741_P745_D0.5360.32
147_L364_W0.5360.32
136_L144_Y0.5350.32
284_Y288_N0.5340.32
197_T374_S0.5340.32
726_I806_W0.5330.32
740_I807_L0.5330.32
121_H516_P0.5330.32
61_Y818_N0.5330.32
281_L572_Y0.5330.32
618_N708_N0.5320.31
304_W585_Q0.5320.31
346_W356_I0.5310.31
42_V794_L0.5310.31
84_Y314_G0.5300.31
542_P546_I0.5300.31
310_F570_L0.5300.31
480_I522_F0.5300.31
176_R804_P0.5300.31
59_N324_P0.5290.31
537_F584_L0.5290.31
754_T763_P0.5290.31
317_L343_V0.5290.31
481_V763_P0.5290.31
319_N584_L0.5290.31
416_P718_W0.5290.31
65_N815_S0.5280.31
185_S774_I0.5280.31
30_N34_G0.5280.31
613_Q695_R0.5280.31
639_Y763_P0.5280.31
202_D556_F0.5270.31
452_F522_F0.5270.31
316_I723_F0.5260.31
157_Y160_T0.5260.31
642_A704_L0.5260.31
226_P811_Y0.5260.31
502_G630_N0.5250.31
427_S731_G0.5250.31
565_D748_T0.5240.31
149_A152_Q0.5230.31
231_G235_V0.5230.31
100_L120_M0.5230.31
515_E653_L0.5230.31
585_Q811_Y0.5230.31
677_A687_N0.5220.31
396_N405_R0.5220.31
460_K522_F0.5220.31
63_D300_A0.5210.31
616_A713_I0.5210.31
323_L566_I0.5210.31
635_T709_L0.5210.31
427_S818_N0.5210.31
578_I582_M0.5200.30
92_F104_N0.5200.30
746_P752_G0.5190.30
192_M465_P0.5190.30
457_N579_S0.5190.30
22_F49_V0.5180.30
702_I713_I0.5180.30
52_P141_P0.5170.30
216_S572_Y0.5170.30
380_I386_Y0.5170.30
129_A469_L0.5160.30
442_S697_S0.5160.30
176_R450_T0.5160.30
239_D457_N0.5150.30
331_W467_Q0.5150.30
312_T396_N0.5150.30
203_E488_I0.5150.30
132_S189_G0.5150.30
615_T798_F0.5150.30
639_Y721_V0.5140.30
154_V188_F0.5140.30
84_Y811_Y0.5140.30
172_L572_Y0.5130.30
68_A798_F0.5130.30
651_K687_N0.5130.30
100_L647_N0.5120.30
333_P773_F0.5120.30
126_P187_A0.5120.30
486_P518_G0.5120.30
68_A94_I0.5120.30
480_I690_F0.5110.30
79_F91_L0.5110.30
735_L747_H0.5110.30
538_A768_G0.5110.30
348_L366_L0.5110.30
22_F25_S0.5100.30
77_D449_S0.5100.30
187_A364_W0.5090.30
133_A363_A0.5090.30
368_T538_A0.5080.29
414_N512_T0.5080.29
121_H336_L0.5080.29
158_I393_Y0.5080.29
108_W768_G0.5080.29
530_D804_P0.5080.29
300_A749_L0.5080.29
509_G512_T0.5070.29
413_N512_T0.5070.29
309_D611_S0.5070.29
26_L30_N0.5070.29
187_A790_P0.5070.29
414_N513_K0.5060.29
507_L512_T0.5060.29
95_E98_G0.5060.29
342_N698_F0.5050.29
431_S439_T0.5050.29
373_S467_Q0.5050.29
111_A532_V0.5050.29
118_I706_E0.5050.29
690_F738_G0.5050.29
22_F804_P0.5050.29
715_Q810_K0.5050.29
379_E515_E0.5050.29
193_G439_T0.5040.29
94_I722_H0.5040.29
735_L763_P0.5040.29
390_G576_V0.5040.29
199_G556_F0.5040.29
459_A568_H0.5040.29
185_S698_F0.5040.29
78_L334_L0.5040.29
92_F502_G0.5030.29
752_G763_P0.5030.29
308_S475_H0.5030.29
319_N367_T0.5030.29
42_V793_S0.5020.29
284_Y741_P0.5020.29
75_L447_D0.5020.29
303_S537_F0.5020.29
305_V481_V0.5020.29
417_L693_L0.5020.29
450_T532_V0.5010.29
32_F44_M0.5010.29
72_A77_D0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4e57A 2 0.7793 100 0.268 Contact Map
4hstB 1 0.6104 100 0.442 Contact Map
1fm2B 1 0.5899 100 0.473 Contact Map
4wksC 1 0.6019 100 0.49 Contact Map
3k3wB 1 0.6007 100 0.494 Contact Map
1gk9B 1 0.6007 100 0.496 Contact Map
1cp9B 1 0.5995 100 0.497 Contact Map
4pemA 1 0.2992 100 0.757 Contact Map
4hstA 1 0.2593 100 0.764 Contact Map
1cp9A 2 0.228 100 0.783 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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