GREMLIN Database
Q97XR7 - Uncharacterized protein
UniProt: Q97XR7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 129 (117)
Sequences: 461 (421)
Seq/√Len: 38.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_K118_E6.1211.00
13_L125_K4.8141.00
15_D41_K3.7241.00
58_D85_T2.9131.00
107_K111_E2.8391.00
42_A121_I2.6901.00
22_T34_W2.4351.00
18_T22_T2.3911.00
87_H105_Y2.3791.00
11_Q29_Y2.3541.00
80_E116_K2.2971.00
30_A34_W2.2691.00
43_L59_L2.2270.99
15_D34_W1.8210.98
115_K118_E1.7220.97
63_L81_V1.6450.96
13_L121_I1.6390.96
9_L42_A1.6370.96
11_Q105_Y1.5920.95
21_D27_H1.5600.94
86_L109_D1.5570.94
46_L66_I1.5450.94
71_G74_V1.5330.94
21_D25_T1.5280.94
39_A84_L1.5190.93
14_E29_Y1.4760.92
28_Y110_A1.4550.92
87_H113_L1.4380.91
17_A27_H1.4070.91
46_L74_V1.3990.90
59_L81_V1.3750.89
114_V118_E1.3440.88
50_G66_I1.3270.88
18_T30_A1.3070.87
18_T34_W1.2400.84
74_V123_W1.1980.82
35_A117_A1.1920.81
9_L45_A1.1800.81
106_S109_D1.1720.80
38_A114_V1.1700.80
12_A42_A1.1510.79
41_K94_P1.1500.79
115_K119_K1.1480.79
22_T30_A1.1450.79
85_T88_Y1.1430.79
18_T27_H1.1350.78
59_L85_T1.1230.77
83_K112_E1.1150.77
35_A115_K1.0980.76
10_R103_S1.0780.74
32_A113_L1.0730.74
84_L117_A1.0510.72
85_T90_I1.0430.72
33_F88_Y1.0300.71
19_A35_A1.0300.71
23_I110_A1.0240.70
15_D22_T0.9850.67
44_K57_H0.9740.67
16_L117_A0.9710.66
122_E126_R0.9700.66
118_E122_E0.9550.65
7_K34_W0.9210.62
80_E119_K0.9050.61
23_I32_A0.9030.61
77_I120_V0.8890.59
14_E22_T0.8870.59
17_A20_K0.8740.58
33_F92_R0.8600.57
41_K55_R0.8590.57
5_A12_A0.8470.56
22_T41_K0.8470.56
39_A120_V0.8430.55
23_I114_V0.8350.55
114_V121_I0.8220.53
23_I107_K0.8210.53
7_K48_I0.8200.53
47_L66_I0.8110.52
109_D113_L0.8090.52
47_L62_L0.7900.51
14_E104_L0.7820.50
14_E30_A0.7810.50
15_D94_P0.7810.50
20_K114_V0.7790.50
109_D116_K0.7780.49
39_A81_V0.7750.49
31_S110_A0.7680.49
47_L109_D0.7660.48
77_I81_V0.7520.47
112_E115_K0.7510.47
27_H33_F0.7400.46
36_E110_A0.7370.46
32_A109_D0.7360.46
63_L73_S0.7360.46
111_E115_K0.7360.46
88_Y96_A0.7340.46
20_K24_T0.7320.45
19_A114_V0.7280.45
33_F89_T0.7240.45
88_Y91_S0.7220.44
9_L125_K0.6980.42
15_D18_T0.6970.42
28_Y31_S0.6900.42
90_I95_D0.6860.41
34_W41_K0.6840.41
47_L52_K0.6770.40
33_F39_A0.6690.40
68_E76_E0.6680.40
51_G85_T0.6630.39
83_K113_L0.6550.39
7_K56_T0.6520.38
47_L65_I0.6510.38
38_A121_I0.6480.38
11_Q102_Y0.6480.38
46_L71_G0.6470.38
63_L77_I0.6340.37
36_E87_H0.6330.37
16_L20_K0.6300.36
87_H91_S0.6250.36
8_W93_Y0.6210.36
12_A79_S0.6170.35
12_A38_A0.6170.35
105_Y113_L0.6160.35
80_E83_K0.6140.35
51_G117_A0.6130.35
11_Q54_E0.6120.35
5_A49_A0.6100.35
40_E57_H0.6090.35
59_L86_L0.6080.35
57_H93_Y0.5980.34
40_E94_P0.5980.34
37_Q84_L0.5950.34
38_A68_E0.5940.33
86_L106_S0.5940.33
83_K87_H0.5880.33
14_E27_H0.5880.33
46_L124_V0.5870.33
16_L51_G0.5810.32
27_H30_A0.5780.32
64_E83_K0.5670.31
93_Y126_R0.5670.31
46_L79_S0.5660.31
56_T90_I0.5620.31
85_T89_T0.5590.31
43_L56_T0.5580.31
6_E23_I0.5560.30
121_I125_K0.5490.30
67_K74_V0.5470.30
10_R73_S0.5460.30
97_A104_L0.5440.30
71_G108_E0.5430.29
81_V85_T0.5420.29
27_H34_W0.5400.29
32_A87_H0.5390.29
10_R118_E0.5360.29
66_I74_V0.5340.29
89_T97_A0.5320.29
56_T66_I0.5310.29
82_I105_Y0.5310.29
76_E120_V0.5300.29
38_A75_E0.5260.28
81_V120_V0.5250.28
85_T104_L0.5250.28
75_E108_E0.5240.28
66_I123_W0.5240.28
50_G91_S0.5240.28
41_K48_I0.5230.28
80_E112_E0.5230.28
8_W94_P0.5140.27
108_E120_V0.5100.27
28_Y33_F0.5080.27
43_L60_N0.5030.27
66_I71_G0.5020.26
6_E107_K0.5010.26
32_A37_Q0.5010.26
36_E94_P0.5000.26
27_H31_S0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1ufbA 3 0.9767 100 0.264 Contact Map
3o10A 2 0.9922 100 0.272 Contact Map
1wolA 1 0.938 100 0.297 Contact Map
1o3uA 2 0.907 100 0.336 Contact Map
4nqfA 2 0.9457 100 0.351 Contact Map
2hsbA 2 0.9302 99.9 0.399 Contact Map
2jpuA 1 0.8682 91.3 0.87 Contact Map
1knyA 2 0.845 40.1 0.916 Contact Map
3mfnA 2 0.8992 33.8 0.919 Contact Map
4hpqC 2 0.9457 25.1 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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