Q97XP9 - SULSO - GREMLIN Contacts

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Q97XP9 - N-methylhydantoinase B (HuyB-1)

UniProt:	Q97XP9	Sequences: MVDPFTLEIIKNGLVVASEEMFYAFGRTAKSPVIYEVLDYAVGITDSKGRGLVAQAPGVPGFSGVLDFTIREVLGKWKSDINPGDVIATNIPYSGGTHLNDVALIMPMFTKDTLVGFIVNKGHWSEIGGMHFGSWSSDATEIFQEGLQLPNIKLYIGGKPNRDVIDIISANSRMPNATLGDMEAQIASMKIAARRINTLIEKYGLDNVIEAMDKLIEDGVKLSKLKLAKLPKGKFEAEDYIDDDGISDNPVYVKVRVSITDNEFIVDFTGSSNQVNGPINSPLPATVSAVRETYMAITDPHALPNAGFFSPLKVIAPEGSIFNPRKPAPTSTYWESMSYATDLVWKALAPYIPDKLSAGHFLSILATILGGYDEKTGEPFAIVEPQPGGWGGCNDQDGESALVASGDGETYIASAEVYERKMPILVERESLNTEDGPGHGKYRGGLGIIKDYVVLSKEAYFTVSIGRSKFPPWGINGGFSGPPNYAVIYKKGEKPRVARKIAAIKLEYGDKVSLHSAGGGGWGDPLDRDPELVLQDVKNEYITHDIAQKVYGVVIENGKVNYDKTLNLRNIMRRSKILSGTVQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	583 (511)
Sequences:	2341 (1374)
Seq/√Len:	60.8

SULSO - Q97XP9 Q97WV3 Q97UR7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
427_E	453_V	5.899	1.00
263_E	313_K	4.837	1.00
82_N	157_G	4.728	1.00
395_D	442_Y	4.538	1.00
81_I	87_I	4.175	1.00
441_K	527_D	4.121	1.00
232_K	261_D	4.077	1.00
485_Y	515_H	4.021	1.00
269_T	315_I	3.872	1.00
220_V	310_S	3.810	1.00
265_I	315_I	3.763	1.00
237_A	346_K	3.754	1.00
265_I	313_K	3.605	1.00
220_V	224_K	3.322	1.00
108_M	118_I	3.303	1.00
318_E	325_R	3.295	1.00
83_P	112_D	3.182	1.00
106_M	189_M	3.049	1.00
140_T	144_Q	3.013	1.00
217_E	310_S	2.931	1.00
234_K	258_S	2.926	1.00
88_A	102_V	2.807	1.00
153_K	156_I	2.795	1.00
400_S	446_L	2.759	1.00
236_E	256_R	2.695	1.00
270_G	317_P	2.682	1.00
428_R	451_D	2.667	1.00
149_L	167_I	2.634	1.00
273_N	317_P	2.570	1.00
451_D	513_S	2.489	1.00
397_D	443_R	2.473	1.00
271_S	321_I	2.436	1.00
156_I	161_N	2.421	1.00
82_N	156_I	2.382	1.00
471_P	483_P	2.378	1.00
453_V	511_K	2.375	1.00
316_A	323_N	2.352	1.00
195_R	198_T	2.306	1.00
427_E	451_D	2.243	1.00
120_N	189_M	2.240	1.00
425_L	455_L	2.189	1.00
490_K	496_R	2.186	1.00
238_E	254_K	2.181	1.00
283_L	316_A	2.179	1.00
317_P	323_N	2.159	1.00
20_E	195_R	2.152	1.00
274_Q	328_A	2.145	1.00
224_K	263_E	2.139	1.00
439_H	479_F	2.108	1.00
255_V	266_V	2.072	1.00
449_I	515_H	2.003	1.00
141_E	144_Q	2.002	1.00
81_I	117_F	1.950	1.00
401_A	431_L	1.949	1.00
76_K	166_D	1.933	1.00
200_I	208_V	1.932	1.00
372_Y	456_S	1.921	1.00
228_A	261_D	1.920	1.00
13_G	202_K	1.912	1.00
234_K	256_R	1.901	1.00
200_I	205_L	1.873	1.00
113_T	209_I	1.870	1.00
490_K	510_D	1.868	1.00
294_Y	312_L	1.867	1.00
235_F	351_Y	1.860	1.00
228_A	262_N	1.860	1.00
252_Y	272_S	1.846	1.00
88_A	104_L	1.843	1.00
458_E	508_Y	1.832	1.00
130_M	138_D	1.828	1.00
232_K	262_N	1.826	1.00
397_D	442_Y	1.824	1.00
124_W	185_Q	1.804	1.00
451_D	511_K	1.801	1.00
393_C	396_Q	1.797	1.00
115_V	200_I	1.779	0.99
439_H	443_R	1.758	0.99
155_Y	186_I	1.751	0.99
487_V	495_P	1.738	0.99
318_E	323_N	1.736	0.99
110_T	201_E	1.736	0.99
232_K	259_I	1.734	0.99
238_E	252_Y	1.731	0.99
390_W	399_E	1.716	0.99
458_E	507_E	1.716	0.99
74_L	117_F	1.706	0.99
431_L	446_L	1.705	0.99
485_Y	497_V	1.703	0.99
427_E	511_K	1.673	0.99
34_I	122_G	1.652	0.99
488_I	506_L	1.648	0.99
216_I	310_S	1.646	0.99
387_P	448_I	1.643	0.99
236_E	254_K	1.640	0.99
253_V	343_L	1.639	0.99
507_E	510_D	1.623	0.99
430_S	449_I	1.621	0.99
476_N	522_W	1.614	0.99
220_V	311_P	1.582	0.99
266_V	312_L	1.580	0.99
434_E	446_L	1.573	0.99
432_N	435_D	1.559	0.99
87_I	153_K	1.554	0.99
266_V	290_V	1.554	0.99
524_D	527_D	1.554	0.99
466_G	501_I	1.549	0.99
106_M	193_A	1.548	0.99
88_A	149_L	1.530	0.98
41_A	62_F	1.518	0.98
10_I	211_A	1.515	0.98
165_I	176_N	1.512	0.98
113_T	205_L	1.509	0.98
368_I	461_F	1.506	0.98
225_L	228_A	1.499	0.98
8_E	11_K	1.498	0.98
230_L	235_F	1.495	0.98
258_S	261_D	1.495	0.98
239_D	343_L	1.485	0.98
415_A	426_V	1.480	0.98
111_K	201_E	1.477	0.98
317_P	320_S	1.465	0.98
473_W	480_S	1.445	0.98
47_S	209_I	1.436	0.98
53_V	212_M	1.436	0.98
226_K	229_K	1.432	0.98
489_Y	493_E	1.428	0.97
386_Q	514_L	1.421	0.97
86_V	106_M	1.419	0.97
239_D	467_R	1.413	0.97
88_A	154_L	1.396	0.97
130_M	144_Q	1.393	0.97
148_Q	326_K	1.393	0.97
110_T	114_L	1.391	0.97
274_Q	325_R	1.376	0.97
292_E	406_G	1.375	0.97
22_F	58_G	1.372	0.97
296_A	345_W	1.370	0.97
156_I	159_K	1.369	0.97
214_K	217_E	1.369	0.97
390_W	405_S	1.369	0.97
162_R	166_D	1.355	0.97
487_V	513_S	1.349	0.96
342_D	467_R	1.343	0.96
432_N	482_P	1.343	0.96
428_R	449_I	1.340	0.96
136_S	139_A	1.340	0.96
353_P	473_W	1.340	0.96
273_N	320_S	1.336	0.96
484_N	517_A	1.331	0.96
283_L	323_N	1.324	0.96
102_V	127_I	1.323	0.96
77_W	151_N	1.322	0.96
488_I	504_I	1.318	0.96
250_P	470_F	1.314	0.96
293_T	344_V	1.312	0.96
13_G	199_L	1.310	0.96
82_N	153_K	1.303	0.96
110_T	115_V	1.302	0.96
197_N	201_E	1.293	0.95
425_L	453_V	1.293	0.95
235_F	259_I	1.292	0.95
454_V	459_A	1.290	0.95
274_Q	319_G	1.288	0.95
258_S	265_I	1.282	0.95
205_L	209_I	1.280	0.95
154_L	186_I	1.277	0.95
193_A	197_N	1.276	0.95
489_Y	510_D	1.265	0.95
433_T	446_L	1.263	0.95
489_Y	492_G	1.260	0.95
320_S	323_N	1.256	0.95
263_E	311_P	1.252	0.95
93_Y	327_P	1.251	0.95
241_I	279_I	1.250	0.95
489_Y	513_S	1.238	0.94
147_L	168_I	1.210	0.94
432_N	515_H	1.205	0.93
257_V	266_V	1.201	0.93
83_P	197_N	1.198	0.93
259_I	262_N	1.198	0.93
471_P	480_S	1.195	0.93
268_F	290_V	1.192	0.93
140_T	276_N	1.189	0.93
346_K	473_W	1.186	0.93
436_G	446_L	1.183	0.93
110_T	200_I	1.183	0.93
74_L	114_L	1.181	0.93
316_A	322_F	1.165	0.92
283_L	287_V	1.164	0.92
487_V	515_H	1.159	0.92
373_D	376_T	1.157	0.92
10_I	14_L	1.156	0.92
21_M	192_A	1.153	0.92
108_M	193_A	1.153	0.92
221_K	225_L	1.151	0.92
250_P	272_S	1.145	0.92
322_F	340_A	1.143	0.91
491_K	507_E	1.141	0.91
102_V	124_W	1.137	0.91
371_G	380_F	1.134	0.91
491_K	510_D	1.131	0.91
432_N	449_I	1.127	0.91
224_K	311_P	1.125	0.91
236_E	252_Y	1.124	0.91
231_P	259_I	1.120	0.91
339_Y	466_G	1.118	0.91
190_K	194_R	1.117	0.90
289_A	341_T	1.108	0.90
217_E	220_V	1.108	0.90
33_V	37_V	1.107	0.90
86_V	155_Y	1.095	0.90
287_V	314_V	1.094	0.90
108_M	196_I	1.092	0.89
232_K	260_T	1.092	0.89
269_T	317_P	1.088	0.89
227_L	259_I	1.087	0.89
221_K	262_N	1.086	0.89
401_A	448_I	1.085	0.89
88_A	164_V	1.081	0.89
139_A	329_P	1.077	0.89
444_G	518_G	1.077	0.89
489_Y	495_P	1.071	0.89
152_I	164_V	1.070	0.88
198_T	202_K	1.070	0.88
208_V	212_M	1.066	0.88
3_D	6_T	1.064	0.88
492_G	495_P	1.064	0.88
465_I	486_A	1.059	0.88
434_E	439_H	1.054	0.88
230_L	259_I	1.053	0.88
213_D	217_E	1.052	0.88
115_V	205_L	1.044	0.87
199_L	203_Y	1.040	0.87
169_S	179_L	1.036	0.87
143_F	326_K	1.027	0.86
71_R	306_A	1.026	0.86
48_K	213_D	1.023	0.86
172_S	175_P	1.022	0.86
194_R	198_T	1.020	0.86
13_G	17_A	1.019	0.86
432_N	447_G	1.016	0.86
52_L	55_Q	1.016	0.86
160_P	165_I	1.016	0.86
426_V	452_Y	1.013	0.86
381_A	413_A	1.013	0.86
256_R	270_G	1.013	0.86
274_Q	327_P	1.009	0.85
86_V	189_M	1.009	0.85
331_S	464_S	1.008	0.85
156_I	163_D	1.008	0.85
103_A	121_K	1.007	0.85
110_T	197_N	1.005	0.85
451_D	489_Y	1.002	0.85
268_F	340_A	0.997	0.85
120_N	188_S	0.992	0.84
359_G	362_L	0.986	0.84
249_N	272_S	0.985	0.84
91_I	150_P	0.983	0.84
361_F	388_G	0.983	0.84
239_D	339_Y	0.982	0.84
368_I	512_V	0.970	0.83
460_Y	505_K	0.970	0.83
271_S	320_S	0.968	0.83
454_V	506_L	0.968	0.83
449_I	513_S	0.968	0.83
160_P	179_L	0.968	0.83
479_F	525_P	0.965	0.83
197_N	200_I	0.964	0.83
224_K	262_N	0.964	0.83
189_M	193_A	0.960	0.82
227_L	232_K	0.958	0.82
237_A	473_W	0.958	0.82
45_T	119_V	0.957	0.82
53_V	56_A	0.954	0.82
230_L	351_Y	0.953	0.82
384_E	450_K	0.951	0.82
488_I	498_A	0.947	0.81
100_N	409_E	0.944	0.81
278_P	329_P	0.943	0.81
461_F	506_L	0.943	0.81
455_L	458_E	0.940	0.81
412_I	429_E	0.939	0.81
220_V	263_E	0.933	0.81
23_Y	26_G	0.930	0.80
115_V	209_I	0.929	0.80
232_K	235_F	0.929	0.80
17_A	199_L	0.929	0.80
86_V	186_I	0.926	0.80
201_E	228_A	0.921	0.80
271_S	317_P	0.921	0.80
435_D	518_G	0.920	0.80
164_V	167_I	0.917	0.79
460_Y	503_A	0.916	0.79
44_I	118_I	0.915	0.79
118_I	193_A	0.912	0.79
161_N	164_V	0.910	0.79
152_I	167_I	0.905	0.78
285_A	333_Y	0.904	0.78
37_V	385_P	0.903	0.78
217_E	221_K	0.897	0.78
2_V	214_K	0.890	0.77
359_G	473_W	0.888	0.77
152_I	161_N	0.885	0.77
380_F	459_A	0.882	0.77
271_S	322_F	0.882	0.77
154_L	161_N	0.882	0.77
227_L	235_F	0.876	0.76
237_A	343_L	0.866	0.75
443_R	446_L	0.864	0.75
325_R	328_A	0.860	0.75
240_Y	252_Y	0.858	0.75
191_I	195_R	0.857	0.75
172_S	178_T	0.856	0.74
62_F	65_V	0.852	0.74
275_V	279_I	0.850	0.74
251_V	275_V	0.844	0.73
224_K	232_K	0.843	0.73
238_E	250_P	0.842	0.73
441_K	524_D	0.840	0.73
68_F	287_V	0.840	0.73
475_I	522_W	0.837	0.73
394_N	442_Y	0.833	0.72
179_L	183_E	0.833	0.72
290_V	314_V	0.833	0.72
83_P	193_A	0.830	0.72
240_Y	470_F	0.828	0.72
65_V	97_T	0.826	0.72
73_V	87_I	0.818	0.71
342_D	388_G	0.817	0.71
479_F	521_G	0.814	0.71
105_I	117_F	0.813	0.71
335_E	360_H	0.813	0.71
461_F	512_V	0.812	0.71
234_K	238_E	0.811	0.70
91_I	151_N	0.802	0.70
71_R	75_G	0.801	0.69
67_D	306_A	0.798	0.69
114_L	117_F	0.797	0.69
226_K	230_L	0.796	0.69
169_S	176_N	0.794	0.69
349_A	476_N	0.792	0.69
26_G	40_Y	0.791	0.68
216_I	220_V	0.791	0.68
388_G	391_G	0.791	0.68
153_K	161_N	0.791	0.68
204_G	207_N	0.788	0.68
251_V	321_I	0.787	0.68
25_F	122_G	0.782	0.68
418_Y	426_V	0.781	0.68
234_K	254_K	0.779	0.67
324_P	328_A	0.778	0.67
441_K	526_L	0.776	0.67
379_P	456_S	0.776	0.67
91_I	148_Q	0.775	0.67
65_V	69_T	0.774	0.67
224_K	261_D	0.773	0.67
335_E	383_V	0.771	0.67
335_E	363_S	0.771	0.67
397_D	524_D	0.771	0.67
443_R	521_G	0.769	0.66
216_I	306_A	0.768	0.66
37_V	403_V	0.767	0.66
165_I	175_P	0.765	0.66
104_L	186_I	0.764	0.66
190_K	193_A	0.764	0.66
191_I	194_R	0.764	0.66
467_R	472_P	0.764	0.66
27_R	512_V	0.762	0.66
499_R	502_A	0.761	0.65
149_L	154_L	0.760	0.65
302_A	308_F	0.758	0.65
21_M	42_V	0.754	0.65
104_L	189_M	0.754	0.65
222_L	299_D	0.752	0.65
353_P	358_A	0.748	0.64
41_A	63_S	0.747	0.64
466_G	500_K	0.744	0.64
77_W	87_I	0.743	0.64
259_I	264_F	0.741	0.63
490_K	493_E	0.740	0.63
75_G	83_P	0.738	0.63
6_T	203_Y	0.735	0.63
35_Y	421_K	0.735	0.63
219_G	305_N	0.734	0.63
69_T	89_T	0.733	0.63
61_G	407_D	0.733	0.63
394_N	522_W	0.733	0.63
106_M	120_N	0.732	0.62
24_A	191_I	0.731	0.62
266_V	294_Y	0.728	0.62
286_T	316_A	0.726	0.62
490_K	494_K	0.725	0.62
74_L	81_I	0.724	0.62
451_D	515_H	0.723	0.62
339_Y	472_P	0.723	0.62
453_V	509_G	0.723	0.62
75_G	340_A	0.723	0.62
270_G	316_A	0.722	0.61
270_G	273_N	0.722	0.61
487_V	497_V	0.721	0.61
6_T	207_N	0.720	0.61
219_G	223_S	0.718	0.61
391_G	444_G	0.716	0.61
243_D	501_I	0.716	0.61
121_K	333_Y	0.714	0.61
155_Y	160_P	0.712	0.60
359_G	472_P	0.712	0.60
68_F	284_P	0.711	0.60
492_G	496_R	0.710	0.60
221_K	228_A	0.710	0.60
493_E	496_R	0.709	0.60
85_D	153_K	0.708	0.60
49_G	74_L	0.706	0.60
243_D	500_K	0.706	0.60
294_Y	348_L	0.705	0.60
192_A	344_V	0.704	0.59
45_T	66_L	0.703	0.59
228_A	232_K	0.702	0.59
244_D	277_G	0.702	0.59
281_S	285_A	0.701	0.59
61_G	289_A	0.700	0.59
73_V	105_I	0.700	0.59
153_K	157_G	0.699	0.59
149_L	152_I	0.698	0.59
74_L	78_K	0.698	0.59
72_E	75_G	0.693	0.58
83_P	157_G	0.691	0.58
8_E	12_N	0.689	0.58
118_I	192_A	0.689	0.58
260_T	265_I	0.689	0.58
234_K	260_T	0.689	0.58
41_A	55_Q	0.689	0.58
429_E	450_K	0.689	0.58
291_R	309_F	0.687	0.58
77_W	156_I	0.686	0.57
367_T	370_G	0.686	0.57
2_V	6_T	0.686	0.57
81_I	114_L	0.686	0.57
382_I	452_Y	0.686	0.57
159_K	469_K	0.683	0.57
85_D	157_G	0.682	0.57
218_D	222_L	0.680	0.57
147_L	171_N	0.678	0.57
99_L	146_G	0.678	0.57
462_T	503_A	0.677	0.56
110_T	205_L	0.677	0.56
439_H	525_P	0.676	0.56
366_A	383_V	0.674	0.56
368_I	514_L	0.673	0.56
160_P	183_E	0.672	0.56
69_T	282_P	0.672	0.56
166_D	318_E	0.670	0.56
285_A	337_M	0.670	0.56
403_V	410_T	0.668	0.55
295_M	300_P	0.666	0.55
30_K	180_G	0.665	0.55
230_L	352_I	0.663	0.55
108_M	192_A	0.662	0.55
63_S	409_E	0.659	0.54
487_V	506_L	0.659	0.54
241_I	466_G	0.659	0.54
342_D	359_G	0.658	0.54
9_I	203_Y	0.658	0.54
37_V	410_T	0.658	0.54
164_V	491_K	0.655	0.54
59_V	410_T	0.654	0.54
75_G	111_K	0.653	0.54
111_K	260_T	0.653	0.54
269_T	318_E	0.652	0.54
251_V	343_L	0.651	0.54
387_P	403_V	0.651	0.54
243_D	275_V	0.651	0.54
7_L	10_I	0.651	0.54
45_T	52_L	0.651	0.54
142_I	327_P	0.650	0.53
369_L	461_F	0.649	0.53
263_E	310_S	0.648	0.53
238_E	469_K	0.648	0.53
38_L	57_P	0.647	0.53
226_K	298_T	0.646	0.53
351_Y	357_S	0.646	0.53
385_P	410_T	0.646	0.53
333_Y	407_D	0.646	0.53
78_K	117_F	0.646	0.53
26_G	38_L	0.645	0.53
22_F	40_Y	0.645	0.53
488_I	512_V	0.643	0.53
391_G	519_G	0.641	0.52
33_V	385_P	0.640	0.52
279_I	329_P	0.640	0.52
75_G	198_T	0.639	0.52
343_L	467_R	0.639	0.52
229_K	232_K	0.638	0.52
392_G	442_Y	0.638	0.52
490_K	495_P	0.638	0.52
380_F	456_S	0.638	0.52
397_D	521_G	0.637	0.52
255_V	343_L	0.636	0.52
206_D	210_E	0.634	0.52
113_T	206_D	0.634	0.52
384_E	409_E	0.633	0.52
395_D	441_K	0.631	0.51
172_S	177_A	0.630	0.51
58_G	62_F	0.629	0.51
73_V	77_W	0.629	0.51
29_A	342_D	0.628	0.51
159_K	260_T	0.628	0.51
385_P	403_V	0.627	0.51
243_D	250_P	0.627	0.51
372_Y	379_P	0.626	0.51
157_G	325_R	0.624	0.51
206_D	505_K	0.624	0.51
108_M	116_G	0.623	0.50
363_S	383_V	0.622	0.50
306_A	310_S	0.621	0.50
28_T	40_Y	0.620	0.50
489_Y	511_K	0.619	0.50
363_S	366_A	0.617	0.50
88_A	168_I	0.617	0.50
24_A	106_M	0.617	0.50
187_A	305_N	0.616	0.50
470_F	483_P	0.616	0.50
35_Y	333_Y	0.616	0.50
124_W	409_E	0.614	0.49
196_I	496_R	0.614	0.49
236_E	441_K	0.613	0.49
24_A	28_T	0.612	0.49
282_P	324_P	0.609	0.49
151_N	204_G	0.608	0.49
196_I	200_I	0.608	0.49
105_I	119_V	0.606	0.49
434_E	524_D	0.606	0.49
223_S	282_P	0.606	0.49
176_N	378_E	0.605	0.48
126_E	466_G	0.605	0.48
75_G	166_D	0.605	0.48
83_P	113_T	0.604	0.48
384_E	410_T	0.602	0.48
441_K	476_N	0.602	0.48
403_V	408_G	0.602	0.48
443_R	479_F	0.601	0.48
120_N	185_Q	0.601	0.48
255_V	268_F	0.600	0.48
344_V	502_A	0.600	0.48
110_T	113_T	0.598	0.48
201_E	508_Y	0.596	0.47
131_H	136_S	0.595	0.47
143_F	172_S	0.593	0.47
73_V	89_T	0.593	0.47
339_Y	342_D	0.593	0.47
393_C	399_E	0.592	0.47
43_G	58_G	0.592	0.47
236_E	350_P	0.592	0.47
29_A	148_Q	0.590	0.47
235_F	262_N	0.590	0.47
244_D	275_V	0.590	0.47
124_W	295_M	0.589	0.47
44_I	196_I	0.588	0.46
30_K	249_N	0.588	0.46
111_K	206_D	0.586	0.46
474_G	480_S	0.586	0.46
474_G	478_G	0.585	0.46
281_S	286_T	0.585	0.46
34_I	403_V	0.585	0.46
442_Y	511_K	0.584	0.46
172_S	182_M	0.583	0.46
229_K	261_D	0.583	0.46
198_T	522_W	0.583	0.46
239_D	473_W	0.582	0.46
4_P	24_A	0.582	0.46
60_P	66_L	0.581	0.46
279_I	321_I	0.581	0.46
459_A	506_L	0.581	0.46
109_F	114_L	0.581	0.46
302_A	317_P	0.580	0.46
93_Y	97_T	0.579	0.45
14_L	212_M	0.579	0.45
201_E	526_L	0.579	0.45
315_I	318_E	0.576	0.45
226_K	306_A	0.575	0.45
254_K	270_G	0.575	0.45
45_T	62_F	0.574	0.45
33_V	403_V	0.574	0.45
232_K	263_E	0.574	0.45
256_R	315_I	0.574	0.45
488_I	495_P	0.574	0.45
397_D	525_P	0.574	0.45
283_L	318_E	0.573	0.45
256_R	269_T	0.571	0.45
11_K	15_V	0.570	0.44
148_Q	151_N	0.570	0.44
249_N	257_V	0.568	0.44
19_E	22_F	0.568	0.44
292_E	338_S	0.567	0.44
490_K	507_E	0.566	0.44
47_S	113_T	0.566	0.44
135_W	334_W	0.566	0.44
131_H	138_D	0.565	0.44
203_Y	208_V	0.564	0.44
144_Q	171_N	0.564	0.44
471_P	482_P	0.564	0.44
363_S	517_A	0.564	0.44
458_E	505_K	0.563	0.44
334_W	383_V	0.562	0.44
142_I	274_Q	0.561	0.43
17_A	288_S	0.561	0.43
333_Y	337_M	0.561	0.43
37_V	408_G	0.560	0.43
163_D	166_D	0.560	0.43
128_G	173_R	0.560	0.43
194_R	197_N	0.559	0.43
341_T	407_D	0.557	0.43
44_I	108_M	0.557	0.43
255_V	347_A	0.556	0.43
111_K	114_L	0.556	0.43
86_V	104_L	0.555	0.43
267_D	315_I	0.554	0.43
80_D	153_K	0.553	0.43
131_H	139_A	0.551	0.42
91_I	94_S	0.551	0.42
106_M	190_K	0.550	0.42
456_S	508_Y	0.550	0.42
261_D	265_I	0.550	0.42
29_A	36_E	0.550	0.42
369_L	459_A	0.550	0.42
93_Y	150_P	0.550	0.42
93_Y	192_A	0.549	0.42
157_G	234_K	0.549	0.42
279_I	331_S	0.549	0.42
383_V	464_S	0.549	0.42
80_D	162_R	0.549	0.42
218_D	221_K	0.549	0.42
244_D	279_I	0.548	0.42
78_K	81_I	0.548	0.42
76_K	94_S	0.548	0.42
289_A	337_M	0.548	0.42
59_V	519_G	0.547	0.42
387_P	401_A	0.547	0.42
260_T	313_K	0.546	0.42
55_Q	96_G	0.546	0.42
194_R	228_A	0.546	0.42
130_M	136_S	0.546	0.42
237_A	347_A	0.544	0.42
264_F	294_Y	0.544	0.42
168_I	254_K	0.544	0.42
243_D	249_N	0.544	0.42
494_K	497_V	0.543	0.41
134_S	384_E	0.543	0.41
228_A	263_E	0.543	0.41
125_S	383_V	0.542	0.41
244_D	250_P	0.542	0.41
162_R	165_I	0.542	0.41
162_R	183_E	0.542	0.41
119_V	342_D	0.541	0.41
25_F	33_V	0.540	0.41
166_D	169_S	0.540	0.41
237_A	467_R	0.540	0.41
241_I	432_N	0.539	0.41
47_S	114_L	0.539	0.41
474_G	520_G	0.539	0.41
169_S	266_V	0.538	0.41
82_N	112_D	0.538	0.41
21_M	40_Y	0.538	0.41
71_R	74_L	0.538	0.41
228_A	524_D	0.537	0.41
126_E	137_S	0.537	0.41
266_V	348_L	0.537	0.41
506_L	510_D	0.536	0.41
281_S	333_Y	0.535	0.41
34_I	410_T	0.534	0.40
95_G	100_N	0.533	0.40
333_Y	403_V	0.533	0.40
252_Y	469_K	0.533	0.40
491_K	495_P	0.532	0.40
521_G	525_P	0.532	0.40
312_L	343_L	0.531	0.40
465_I	502_A	0.531	0.40
467_R	473_W	0.529	0.40
49_G	129_G	0.529	0.40
111_K	205_L	0.529	0.40
236_E	250_P	0.529	0.40
429_E	448_I	0.529	0.40
265_I	269_T	0.528	0.40
206_D	254_K	0.527	0.40
222_L	225_L	0.527	0.40
123_H	181_D	0.527	0.40
385_P	407_D	0.527	0.40
47_S	312_L	0.526	0.40
116_G	208_V	0.526	0.40
41_A	60_P	0.526	0.40
70_I	105_I	0.526	0.40
161_N	166_D	0.526	0.40
2_V	210_E	0.525	0.40
306_A	312_L	0.525	0.40
41_A	61_G	0.525	0.40
240_Y	340_A	0.525	0.40
259_I	313_K	0.524	0.39
434_E	443_R	0.524	0.39
270_G	323_N	0.524	0.39
38_L	421_K	0.524	0.39
113_T	159_K	0.524	0.39
41_A	288_S	0.524	0.39
35_Y	409_E	0.523	0.39
237_A	471_P	0.521	0.39
178_T	417_V	0.521	0.39
201_E	433_T	0.521	0.39
223_S	308_F	0.521	0.39
231_P	235_F	0.521	0.39
127_I	172_S	0.521	0.39
286_T	293_T	0.521	0.39
157_G	194_R	0.520	0.39
14_L	208_V	0.519	0.39
402_L	409_E	0.519	0.39
207_N	211_A	0.517	0.39
285_A	332_T	0.517	0.39
463_V	512_V	0.516	0.39
242_D	251_V	0.515	0.38
338_S	407_D	0.515	0.38
69_T	72_E	0.515	0.38
289_A	344_V	0.514	0.38
201_E	213_D	0.514	0.38
268_F	317_P	0.513	0.38
268_F	322_F	0.513	0.38
482_P	515_H	0.513	0.38
255_V	346_K	0.512	0.38
112_D	260_T	0.512	0.38
357_S	362_L	0.511	0.38
417_V	421_K	0.511	0.38
58_G	63_S	0.511	0.38
229_K	469_K	0.511	0.38
447_G	515_H	0.511	0.38
249_N	321_I	0.510	0.38
443_R	449_I	0.510	0.38
206_D	524_D	0.509	0.38
113_T	480_S	0.509	0.38
112_D	397_D	0.509	0.38
31_S	122_G	0.509	0.38
47_S	74_L	0.509	0.38
72_E	105_I	0.509	0.38
497_V	515_H	0.508	0.38
40_Y	57_P	0.508	0.38
167_I	171_N	0.508	0.38
153_K	480_S	0.507	0.38
266_V	344_V	0.507	0.38
242_D	321_I	0.507	0.38
129_G	305_N	0.507	0.38
112_D	152_I	0.506	0.37
491_K	494_K	0.506	0.37
87_I	117_F	0.506	0.37
443_R	524_D	0.505	0.37
154_L	158_G	0.505	0.37
163_D	201_E	0.504	0.37
61_G	188_S	0.504	0.37
27_R	71_R	0.504	0.37
243_D	466_G	0.504	0.37
71_R	91_I	0.503	0.37
36_E	484_N	0.502	0.37
19_E	57_P	0.502	0.37
104_L	141_E	0.502	0.37
293_T	297_I	0.502	0.37
32_P	55_Q	0.502	0.37
426_V	434_E	0.502	0.37
201_E	206_D	0.501	0.37
110_T	194_R	0.501	0.37
266_V	469_K	0.501	0.37
60_P	64_G	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1j5kA	1	0.1132	26.2	0.984	Contact Map
2kzxA	1	0.2041	24.9	0.984	Contact Map
3o6uA	1	0.2024	22	0.985	Contact Map
3by8A	2	0.2024	17	0.985	Contact Map
4xlgB	1	0.0669	16.1	0.985	Contact Map
2ia7A	1	0.1818	12.5	0.986	Contact Map
3dvaI	1	0	12	0.986	Contact Map
2e28A	3	0.1475	10.5	0.987	Contact Map
3cwfA	2	0.1732	10.4	0.987	Contact Map
2yfqA	5	0.3225	10.3	0.987	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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