Q97XP3 - SULSO - GREMLIN Contacts

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Q97XP3 - N-methylhydantoinase A related protein (HuyA-like)

UniProt:	Q97XP3	Sequences: MDMMWISYHLKKGGRRLRIRIGIDIGSTHTDAVALEGKELIVADKVMTTPDLTTGLLNAISRVMKKLGERKNEVDTLMIGTTHGLNALHQGKGLNRVATIRIGLPAGEGVPPVFDWPEQLSNFVTYRYMVRGGHEYTGEEIVELDEGKIKEIAEAINGKVDAIAISSIFSVVNSSHEIRAREILREKGINVPIVLSHEIGGIGLLERENSAILNALILKIFDNLISKIKQLLSSLGIEDVRLFFAQNDGTVASEDFIKSYPIFTVAGPVSNSIRGAHLLTGIKDAIVMDVGGTTTNVGVLHEGYPRESSSVVEIAKIRTNFRMPDIYTMALGGGTIVNKEKIGPESVGYALINKGISWGGDTLTATDVAMIVKGITIDGTNPKLVNNKFPMEYLFSAYTKMVEMWEDAIDLMKTSKDDVTVIVVGGGSIMVPEKLKGAMEVIRPRNAQYANAIGATLTKVGATIERTFSYDQITRENAIKSLINEAKSLAIRAGALNTTIEVREIEEIQIPYLPGNSVKVKVKVVGEFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	529 (495)
Sequences:	3417 (2331)
Seq/√Len:	104.7

SULSO - Q97XP3 Q97XP8 Q97UR6 Q97WV4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
167_S	180_A	6.179	1.00
146_E	179_R	5.774	1.00
150_K	186_E	4.839	1.00
135_E	139_E	4.526	1.00
132_G	140_E	4.407	1.00
131_R	148_K	4.382	1.00
181_R	195_L	4.356	1.00
149_I	180_A	4.073	1.00
179_R	182_E	3.521	1.00
154_E	187_K	3.402	1.00
150_K	187_K	3.370	1.00
338_N	345_E	3.344	1.00
154_E	157_N	3.248	1.00
166_S	208_E	3.195	1.00
181_R	185_R	3.156	1.00
385_V	388_K	3.102	1.00
146_E	183_I	3.028	1.00
153_A	184_L	2.971	1.00
181_R	198_E	2.936	1.00
150_K	183_I	2.880	1.00
97_V	156_I	2.860	1.00
89_H	294_T	2.839	1.00
135_E	141_I	2.820	1.00
126_Y	158_G	2.762	1.00
237_I	240_V	2.751	1.00
101_R	129_M	2.748	1.00
483_I	487_K	2.648	1.00
112_P	115_D	2.647	1.00
32_A	59_A	2.633	1.00
483_I	504_E	2.607	1.00
145_D	148_K	2.588	1.00
194_V	211_A	2.558	1.00
131_R	142_V	2.522	1.00
98_A	208_E	2.507	1.00
420_T	440_E	2.501	1.00
61_S	235_L	2.448	1.00
93_G	216_L	2.441	1.00
48_T	83_H	2.391	1.00
174_S	178_I	2.365	1.00
337_V	393_Y	2.336	1.00
97_V	128_Y	2.333	1.00
95_N	125_T	2.323	1.00
165_I	184_L	2.224	1.00
466_R	481_S	2.217	1.00
58_N	62_R	2.175	1.00
479_I	504_E	2.171	1.00
134_H	176_H	2.169	1.00
282_I	440_E	2.126	1.00
140_E	143_E	2.123	1.00
188_G	191_V	2.122	1.00
92_K	345_E	2.109	1.00
144_L	176_H	2.074	1.00
222_D	258_K	2.049	1.00
287_V	298_G	1.980	1.00
46_V	58_N	1.975	1.00
179_R	183_I	1.958	1.00
134_H	140_E	1.948	1.00
164_A	211_A	1.929	1.00
126_Y	160_V	1.903	1.00
148_K	152_I	1.894	1.00
484_N	488_S	1.888	1.00
488_S	492_R	1.881	1.00
182_E	186_E	1.878	1.00
21_I	60_I	1.858	1.00
163_I	184_L	1.855	1.00
338_N	341_K	1.839	1.00
183_I	187_K	1.833	1.00
491_I	497_N	1.826	1.00
44_D	62_R	1.820	1.00
466_R	485_E	1.787	1.00
350_A	358_W	1.780	1.00
391_M	395_F	1.778	1.00
178_I	198_E	1.777	1.00
178_I	182_E	1.765	1.00
144_L	180_A	1.754	1.00
32_A	63_V	1.745	1.00
165_I	180_A	1.736	1.00
371_I	386_N	1.707	1.00
147_G	150_K	1.693	1.00
91_G	317_I	1.690	1.00
36_E	40_L	1.676	1.00
131_R	145_D	1.665	1.00
94_L	161_D	1.659	1.00
48_T	55_G	1.655	1.00
354_K	361_D	1.645	1.00
89_H	330_A	1.641	1.00
178_I	197_H	1.631	1.00
165_I	195_L	1.630	1.00
466_R	478_A	1.626	1.00
51_D	54_T	1.613	1.00
286_I	405_W	1.605	1.00
146_E	150_K	1.600	1.00
464_I	486_A	1.585	1.00
271_N	455_A	1.574	1.00
480_K	483_I	1.566	1.00
336_I	364_T	1.559	1.00
49_T	55_G	1.557	1.00
294_T	328_T	1.551	1.00
480_K	484_N	1.543	1.00
370_M	375_I	1.539	1.00
464_I	489_L	1.530	1.00
369_A	431_V	1.523	1.00
420_T	442_I	1.512	1.00
296_N	328_T	1.510	1.00
91_G	216_L	1.508	1.00
97_V	152_I	1.505	1.00
70_R	73_E	1.497	1.00
134_H	173_N	1.495	1.00
84_G	217_I	1.490	1.00
398_Y	431_V	1.487	1.00
479_I	483_I	1.476	1.00
192_P	218_L	1.471	1.00
132_G	142_V	1.452	1.00
266_A	296_N	1.442	1.00
144_L	179_R	1.434	1.00
229_K	255_D	1.433	1.00
262_I	321_F	1.432	1.00
225_I	254_E	1.428	1.00
423_V	432_P	1.414	1.00
149_I	152_I	1.414	1.00
476_E	480_K	1.414	1.00
365_A	397_A	1.411	1.00
105_P	127_R	1.409	1.00
79_I	224_L	1.407	1.00
203_G	519_K	1.405	1.00
273_I	298_G	1.401	1.00
95_N	161_D	1.401	1.00
34_A	63_V	1.391	1.00
54_T	58_N	1.372	1.00
194_V	214_N	1.367	1.00
183_I	186_E	1.366	1.00
487_K	500_I	1.366	1.00
33_V	449_Y	1.365	1.00
128_Y	156_I	1.363	1.00
242_L	254_E	1.361	1.00
140_E	176_H	1.360	1.00
276_A	287_V	1.357	1.00
130_V	149_I	1.352	0.99
423_V	429_I	1.346	0.99
337_V	368_V	1.345	0.99
128_Y	155_A	1.342	0.99
395_F	435_L	1.342	0.99
470_Y	474_T	1.339	0.99
374_G	394_L	1.339	0.99
266_A	328_T	1.335	0.99
288_M	295_T	1.332	0.99
266_A	294_T	1.322	0.99
509_Q	521_K	1.321	0.99
491_I	500_I	1.317	0.99
147_G	151_E	1.314	0.99
165_I	181_R	1.296	0.99
153_A	180_A	1.293	0.99
163_I	188_G	1.272	0.99
87_A	220_I	1.272	0.99
355_G	370_M	1.267	0.99
182_E	185_R	1.266	0.99
400_K	403_E	1.262	0.99
174_S	197_H	1.256	0.99
285_A	422_I	1.247	0.99
487_K	491_I	1.240	0.99
36_E	42_V	1.235	0.99
221_F	264_T	1.232	0.99
175_S	178_I	1.230	0.99
346_S	349_Y	1.226	0.99
50_P	349_Y	1.219	0.99
150_K	154_E	1.217	0.99
128_Y	152_I	1.217	0.99
283_K	302_E	1.210	0.99
178_I	181_R	1.210	0.99
166_S	196_S	1.208	0.99
464_I	485_E	1.201	0.99
496_L	499_T	1.198	0.99
399_T	435_L	1.184	0.99
149_I	183_I	1.182	0.99
505_I	521_K	1.180	0.99
99_T	152_I	1.178	0.99
482_L	485_E	1.176	0.99
88_L	213_L	1.174	0.99
99_T	130_V	1.168	0.98
21_I	74_V	1.168	0.98
277_H	305_P	1.165	0.98
151_E	154_E	1.163	0.98
474_T	477_N	1.159	0.98
155_A	158_G	1.156	0.98
229_K	258_K	1.155	0.98
166_S	211_A	1.153	0.98
196_S	211_A	1.152	0.98
64_M	71_K	1.146	0.98
477_N	480_K	1.143	0.98
265_V	319_T	1.127	0.98
130_V	152_I	1.124	0.98
376_T	379_G	1.121	0.98
376_T	380_T	1.118	0.98
503_R	523_K	1.112	0.98
478_A	481_S	1.111	0.98
184_L	187_K	1.110	0.98
104_L	212_I	1.107	0.98
31_D	45_K	1.096	0.98
222_D	226_S	1.096	0.98
87_A	92_K	1.095	0.98
103_G	204_L	1.089	0.98
149_I	153_A	1.080	0.97
71_K	74_V	1.080	0.97
200_G	320_N	1.077	0.97
151_E	155_A	1.072	0.97
53_T	227_K	1.072	0.97
96_R	162_A	1.066	0.97
170_S	197_H	1.064	0.97
153_A	183_I	1.061	0.97
88_L	265_V	1.055	0.97
168_I	204_L	1.051	0.97
152_I	184_L	1.048	0.97
369_A	398_Y	1.048	0.97
23_I	77_L	1.046	0.97
25_I	52_L	1.046	0.97
44_D	63_V	1.041	0.97
20_R	76_T	1.041	0.97
483_I	502_V	1.036	0.97
210_S	262_I	1.036	0.97
511_P	519_K	1.031	0.97
350_A	354_K	1.031	0.97
194_V	199_I	1.030	0.97
225_I	244_F	1.027	0.97
175_S	179_R	1.027	0.97
226_S	230_Q	1.022	0.96
304_Y	503_R	1.019	0.96
349_Y	353_N	1.018	0.96
85_L	90_Q	1.015	0.96
51_D	227_K	1.006	0.96
148_K	151_E	1.004	0.96
485_E	488_S	1.003	0.96
248_D	463_T	1.000	0.96
46_V	59_A	0.999	0.96
32_A	44_D	0.996	0.96
481_S	485_E	0.993	0.96
347_V	364_T	0.991	0.96
330_A	335_T	0.991	0.96
22_G	456_T	0.988	0.96
290_V	431_V	0.988	0.96
46_V	55_G	0.983	0.96
250_T	461_G	0.981	0.96
97_V	160_V	0.979	0.96
231_L	234_S	0.977	0.95
329_M	404_M	0.975	0.95
246_Q	263_F	0.973	0.95
278_L	457_L	0.973	0.95
144_L	149_I	0.973	0.95
44_D	59_A	0.967	0.95
161_D	187_K	0.963	0.95
226_S	258_K	0.961	0.95
167_S	176_H	0.960	0.95
160_V	163_I	0.959	0.95
487_K	497_N	0.956	0.95
46_V	62_R	0.955	0.95
152_I	156_I	0.954	0.95
466_R	482_L	0.954	0.95
354_K	363_L	0.953	0.95
428_S	447_A	0.950	0.95
266_A	326_I	0.949	0.95
369_A	374_G	0.946	0.95
57_L	231_L	0.942	0.94
19_I	34_A	0.941	0.94
64_M	74_V	0.940	0.94
95_N	126_Y	0.936	0.94
477_N	481_S	0.935	0.94
153_A	187_K	0.934	0.94
488_S	491_I	0.932	0.94
460_V	495_A	0.929	0.94
146_E	182_E	0.928	0.94
284_D	418_D	0.926	0.94
130_V	180_A	0.924	0.94
462_A	489_L	0.924	0.94
377_I	380_T	0.922	0.94
143_E	179_R	0.918	0.94
132_G	176_H	0.917	0.94
474_T	478_A	0.912	0.93
397_A	401_M	0.911	0.93
156_I	160_V	0.909	0.93
156_I	163_I	0.907	0.93
346_S	353_N	0.897	0.93
57_L	61_S	0.892	0.93
290_V	397_A	0.888	0.93
84_G	264_T	0.887	0.92
70_R	74_V	0.883	0.92
214_N	218_L	0.883	0.92
20_R	75_D	0.882	0.92
432_P	441_V	0.882	0.92
140_E	175_S	0.882	0.92
230_Q	234_S	0.881	0.92
169_F	172_V	0.880	0.92
184_L	188_G	0.876	0.92
282_I	420_T	0.874	0.92
202_I	467_T	0.872	0.92
34_A	67_L	0.869	0.92
88_L	315_A	0.868	0.92
56_L	228_I	0.868	0.92
423_V	443_R	0.865	0.92
52_L	83_H	0.862	0.91
245_A	455_A	0.853	0.91
486_A	502_V	0.850	0.91
368_V	390_P	0.848	0.91
43_A	446_N	0.848	0.91
501_E	504_E	0.847	0.91
246_Q	252_A	0.846	0.91
125_T	160_V	0.846	0.91
472_Q	476_E	0.845	0.91
229_K	233_S	0.843	0.90
95_N	160_V	0.842	0.90
284_D	302_E	0.842	0.90
152_I	155_A	0.841	0.90
363_L	371_I	0.841	0.90
279_L	450_A	0.841	0.90
287_V	294_T	0.840	0.90
491_I	494_G	0.838	0.90
252_A	257_I	0.837	0.90
363_L	389_F	0.836	0.90
80_G	271_N	0.835	0.90
356_I	388_K	0.834	0.90
170_S	196_S	0.831	0.90
20_R	35_L	0.831	0.90
60_I	77_L	0.830	0.90
218_L	261_P	0.829	0.90
473_I	477_N	0.829	0.90
296_N	312_V	0.828	0.90
99_T	167_S	0.826	0.90
165_I	193_I	0.825	0.90
231_L	235_L	0.821	0.89
327_Y	407_D	0.821	0.89
481_S	484_N	0.818	0.89
184_L	191_V	0.816	0.89
485_E	489_L	0.815	0.89
365_A	393_Y	0.814	0.89
23_I	56_L	0.813	0.89
423_V	441_V	0.811	0.89
130_V	144_L	0.809	0.89
34_A	42_V	0.807	0.88
214_N	262_I	0.807	0.88
272_S	424_V	0.806	0.88
96_R	212_I	0.806	0.88
52_L	55_G	0.804	0.88
91_G	122_N	0.803	0.88
339_K	389_F	0.798	0.88
476_E	504_E	0.797	0.88
287_V	424_V	0.792	0.88
290_V	369_A	0.791	0.87
288_M	421_V	0.790	0.87
276_A	285_A	0.789	0.87
208_E	212_I	0.789	0.87
90_Q	345_E	0.785	0.87
290_V	427_G	0.782	0.87
103_G	208_E	0.778	0.87
334_G	346_S	0.778	0.87
146_E	149_I	0.778	0.87
346_S	351_L	0.778	0.87
153_A	188_G	0.778	0.87
143_E	176_H	0.776	0.86
406_E	409_I	0.776	0.86
414_T	419_V	0.772	0.86
99_T	184_L	0.770	0.86
89_H	328_T	0.765	0.86
335_T	342_I	0.759	0.85
290_V	365_A	0.759	0.85
178_I	477_N	0.758	0.85
85_L	328_T	0.756	0.85
71_K	240_V	0.755	0.85
64_M	69_E	0.752	0.85
348_G	359_G	0.751	0.85
91_G	119_Q	0.748	0.84
252_A	256_F	0.748	0.84
59_A	63_V	0.746	0.84
63_V	67_L	0.746	0.84
266_A	327_Y	0.746	0.84
405_W	408_A	0.743	0.84
97_V	163_I	0.742	0.84
151_E	157_N	0.741	0.84
195_L	198_E	0.741	0.84
287_V	451_N	0.741	0.84
164_A	215_A	0.738	0.84
84_G	221_F	0.736	0.83
60_I	64_M	0.736	0.83
433_E	441_V	0.736	0.83
99_T	180_A	0.734	0.83
163_I	191_V	0.732	0.83
433_E	438_A	0.732	0.83
98_A	127_R	0.731	0.83
156_I	159_K	0.729	0.83
80_G	455_A	0.728	0.83
69_E	73_E	0.727	0.83
135_E	173_N	0.727	0.83
25_I	56_L	0.726	0.83
421_V	438_A	0.726	0.83
108_E	115_D	0.724	0.82
429_I	447_A	0.723	0.82
487_K	502_V	0.723	0.82
187_K	191_V	0.721	0.82
161_D	191_V	0.719	0.82
284_D	301_H	0.718	0.82
107_G	168_I	0.717	0.82
297_V	329_M	0.714	0.82
490_A	495_A	0.713	0.81
180_A	183_I	0.713	0.81
98_A	166_S	0.711	0.81
103_G	107_G	0.711	0.81
297_V	404_M	0.711	0.81
495_A	499_T	0.711	0.81
154_E	161_D	0.709	0.81
465_E	509_Q	0.709	0.81
369_A	430_M	0.709	0.81
495_A	500_I	0.706	0.81
64_M	70_R	0.706	0.81
157_N	187_K	0.705	0.81
102_I	105_P	0.704	0.81
145_D	149_I	0.704	0.81
287_V	296_N	0.699	0.80
295_T	328_T	0.699	0.80
152_I	159_K	0.698	0.80
43_A	448_Q	0.698	0.80
363_L	368_V	0.696	0.80
475_R	479_I	0.694	0.80
325_D	412_M	0.693	0.80
354_K	359_G	0.689	0.79
462_A	493_A	0.688	0.79
42_V	67_L	0.686	0.79
53_T	231_L	0.686	0.79
170_S	211_A	0.685	0.79
371_I	384_L	0.685	0.79
323_M	328_T	0.681	0.78
490_A	500_I	0.681	0.78
103_G	116_W	0.681	0.78
110_V	114_F	0.680	0.78
85_L	270_S	0.680	0.78
91_G	315_A	0.678	0.78
424_V	451_N	0.678	0.78
157_N	477_N	0.677	0.78
22_G	305_P	0.676	0.78
334_G	365_A	0.676	0.78
230_Q	233_S	0.676	0.78
312_V	315_A	0.675	0.78
87_A	217_I	0.675	0.78
128_Y	149_I	0.674	0.78
185_R	226_S	0.672	0.77
154_E	182_E	0.671	0.77
491_I	495_A	0.670	0.77
99_T	156_I	0.670	0.77
275_G	450_A	0.668	0.77
203_G	206_E	0.667	0.77
126_Y	156_I	0.665	0.77
19_I	69_E	0.665	0.77
69_E	74_V	0.660	0.76
225_I	257_I	0.659	0.76
350_A	353_N	0.658	0.76
286_I	409_I	0.657	0.76
78_M	251_V	0.655	0.76
146_E	187_K	0.654	0.76
32_A	55_G	0.654	0.76
351_L	356_I	0.653	0.75
128_Y	158_G	0.653	0.75
237_I	241_R	0.651	0.75
21_I	34_A	0.650	0.75
100_I	103_G	0.649	0.75
102_I	110_V	0.649	0.75
377_I	381_N	0.649	0.75
297_V	408_A	0.647	0.75
170_S	174_S	0.645	0.75
266_A	295_T	0.645	0.75
363_L	393_Y	0.645	0.75
77_L	242_L	0.644	0.74
372_V	394_L	0.643	0.74
185_R	198_E	0.642	0.74
376_T	381_N	0.642	0.74
297_V	450_A	0.642	0.74
455_A	519_K	0.639	0.74
85_L	269_V	0.638	0.74
286_I	416_K	0.638	0.74
77_L	237_I	0.638	0.74
19_I	39_E	0.638	0.74
353_N	356_I	0.637	0.74
162_A	192_P	0.637	0.74
245_A	271_N	0.636	0.74
184_L	193_I	0.636	0.74
99_T	188_G	0.635	0.73
276_A	422_I	0.635	0.73
199_I	211_A	0.634	0.73
202_I	519_K	0.634	0.73
226_S	229_K	0.634	0.73
513_L	520_V	0.633	0.73
433_E	436_K	0.632	0.73
349_Y	352_I	0.632	0.73
130_V	148_K	0.630	0.73
98_A	164_A	0.629	0.73
144_L	167_S	0.627	0.72
20_R	37_G	0.627	0.72
84_G	90_Q	0.626	0.72
401_M	431_V	0.626	0.72
152_I	180_A	0.623	0.72
62_R	66_K	0.623	0.72
181_R	193_I	0.623	0.72
56_L	242_L	0.622	0.72
336_I	345_E	0.621	0.72
185_R	193_I	0.618	0.71
58_N	61_S	0.618	0.71
371_I	387_N	0.618	0.71
244_F	264_T	0.617	0.71
312_V	328_T	0.616	0.71
85_L	449_Y	0.616	0.71
343_G	347_V	0.615	0.71
54_T	231_L	0.615	0.71
284_D	419_V	0.613	0.71
96_R	164_A	0.612	0.71
462_A	486_A	0.612	0.71
280_T	450_A	0.611	0.71
162_A	218_L	0.611	0.71
394_L	397_A	0.611	0.71
503_R	508_I	0.611	0.71
428_S	448_Q	0.610	0.70
473_I	484_N	0.609	0.70
367_D	452_A	0.608	0.70
47_M	349_Y	0.608	0.70
257_I	264_T	0.608	0.70
49_T	58_N	0.608	0.70
78_M	217_I	0.607	0.70
213_L	264_T	0.606	0.70
51_D	364_T	0.605	0.70
80_G	326_I	0.605	0.70
505_I	523_K	0.604	0.70
85_L	295_T	0.601	0.69
485_E	522_V	0.601	0.69
50_P	350_A	0.601	0.69
90_Q	451_N	0.600	0.69
213_L	313_E	0.600	0.69
85_L	296_N	0.600	0.69
280_T	285_A	0.598	0.69
290_V	328_T	0.597	0.69
229_K	254_E	0.596	0.69
243_F	251_V	0.595	0.69
465_E	519_K	0.593	0.68
468_F	478_A	0.592	0.68
270_S	324_P	0.592	0.68
473_I	480_K	0.592	0.68
331_L	404_M	0.591	0.68
396_S	400_K	0.591	0.68
134_H	167_S	0.589	0.68
510_I	522_V	0.588	0.68
195_L	199_I	0.588	0.68
297_V	328_T	0.588	0.68
477_N	484_N	0.587	0.67
336_I	347_V	0.586	0.67
214_N	257_I	0.585	0.67
145_D	150_K	0.584	0.67
343_G	346_S	0.584	0.67
499_T	504_E	0.584	0.67
164_A	194_V	0.581	0.67
402_V	406_E	0.580	0.67
390_P	393_Y	0.580	0.67
265_V	321_F	0.579	0.66
488_S	496_L	0.578	0.66
88_L	316_K	0.578	0.66
73_E	76_T	0.578	0.66
484_N	487_K	0.578	0.66
471_D	513_L	0.577	0.66
151_E	473_I	0.576	0.66
150_K	157_N	0.574	0.66
51_D	231_L	0.574	0.66
120_L	123_F	0.572	0.66
378_D	381_N	0.572	0.66
396_S	399_T	0.572	0.66
238_E	241_R	0.571	0.65
288_M	369_A	0.570	0.65
451_N	455_A	0.570	0.65
147_G	154_E	0.569	0.65
61_S	64_M	0.569	0.65
313_E	316_K	0.567	0.65
266_A	270_S	0.567	0.65
351_L	354_K	0.565	0.65
209_N	318_R	0.565	0.65
375_I	429_I	0.565	0.65
71_K	235_L	0.564	0.64
369_A	394_L	0.564	0.64
99_T	128_Y	0.564	0.64
331_L	401_M	0.563	0.64
85_L	245_A	0.563	0.64
137_T	141_I	0.563	0.64
257_I	271_N	0.563	0.64
71_K	96_R	0.562	0.64
27_S	30_T	0.562	0.64
464_I	493_A	0.562	0.64
175_S	487_K	0.562	0.64
155_A	492_R	0.562	0.64
352_I	355_G	0.561	0.64
124_V	314_I	0.561	0.64
247_N	266_A	0.561	0.64
400_K	404_M	0.560	0.64
413_K	417_D	0.560	0.64
490_A	493_A	0.559	0.64
343_G	359_G	0.559	0.64
237_I	283_K	0.557	0.63
42_V	66_K	0.556	0.63
483_I	501_E	0.556	0.63
26_G	31_D	0.555	0.63
399_T	403_E	0.554	0.63
217_I	220_I	0.554	0.63
62_R	65_K	0.554	0.63
145_D	183_I	0.553	0.63
467_T	518_V	0.552	0.63
455_A	517_S	0.552	0.63
72_N	238_E	0.552	0.63
24_D	28_T	0.549	0.62
24_D	31_D	0.549	0.62
232_L	242_L	0.547	0.62
268_P	296_N	0.547	0.62
331_L	365_A	0.547	0.62
88_L	217_I	0.547	0.62
343_G	352_I	0.547	0.62
496_L	500_I	0.546	0.62
374_G	398_Y	0.546	0.62
171_V	202_I	0.544	0.62
89_H	266_A	0.544	0.62
369_A	424_V	0.544	0.62
36_E	382_P	0.543	0.62
299_V	414_T	0.543	0.62
31_D	296_N	0.543	0.62
23_I	60_I	0.543	0.62
276_A	300_L	0.542	0.61
289_D	367_D	0.541	0.61
479_I	502_V	0.541	0.61
327_Y	408_A	0.541	0.61
202_I	450_A	0.541	0.61
52_L	224_L	0.540	0.61
283_K	418_D	0.539	0.61
494_G	498_T	0.539	0.61
299_V	330_A	0.539	0.61
351_L	359_G	0.539	0.61
386_N	390_P	0.539	0.61
266_A	312_V	0.539	0.61
149_I	184_L	0.538	0.61
482_L	486_A	0.538	0.61
422_I	444_P	0.538	0.61
127_R	208_E	0.537	0.61
44_D	66_K	0.537	0.61
41_I	446_N	0.537	0.61
372_V	390_P	0.536	0.61
464_I	482_L	0.535	0.60
113_V	117_P	0.534	0.60
237_I	242_L	0.534	0.60
24_D	27_S	0.534	0.60
348_G	351_L	0.533	0.60
22_G	35_L	0.533	0.60
343_G	351_L	0.533	0.60
142_V	480_K	0.532	0.60
151_E	492_R	0.532	0.60
416_K	419_V	0.531	0.60
429_I	448_Q	0.531	0.60
40_L	122_N	0.531	0.60
56_L	237_I	0.530	0.60
341_K	345_E	0.530	0.60
133_G	168_I	0.530	0.60
23_I	30_T	0.530	0.60
273_I	422_I	0.530	0.60
51_D	371_I	0.530	0.60
484_N	491_I	0.529	0.60
243_F	460_V	0.529	0.60
221_F	320_N	0.529	0.60
28_T	292_G	0.529	0.60
107_G	127_R	0.529	0.60
476_E	483_I	0.528	0.59
182_E	238_E	0.528	0.59
473_I	488_S	0.527	0.59
473_I	476_E	0.527	0.59
296_N	452_A	0.526	0.59
421_V	433_E	0.525	0.59
342_I	396_S	0.524	0.59
38_K	234_S	0.524	0.59
113_V	116_W	0.524	0.59
280_T	442_I	0.523	0.59
151_E	179_R	0.521	0.58
57_L	234_S	0.521	0.58
314_I	328_T	0.520	0.58
472_Q	488_S	0.520	0.58
192_P	222_D	0.520	0.58
162_A	215_A	0.519	0.58
172_V	200_G	0.519	0.58
351_L	357_S	0.519	0.58
371_I	421_V	0.519	0.58
83_H	290_V	0.518	0.58
83_H	275_G	0.518	0.58
432_P	443_R	0.518	0.58
346_S	352_I	0.518	0.58
405_W	409_I	0.518	0.58
85_L	217_I	0.517	0.58
296_N	323_M	0.517	0.58
150_K	153_A	0.516	0.58
28_T	31_D	0.516	0.58
435_L	438_A	0.516	0.58
30_T	48_T	0.515	0.58
89_H	221_F	0.514	0.57
175_S	382_P	0.514	0.57
154_E	183_I	0.513	0.57
221_F	324_P	0.513	0.57
75_D	226_S	0.513	0.57
157_N	238_E	0.512	0.57
26_G	30_T	0.512	0.57
296_N	326_I	0.512	0.57
481_S	488_S	0.512	0.57
94_L	219_K	0.512	0.57
19_I	37_G	0.511	0.57
84_G	245_A	0.511	0.57
398_Y	419_V	0.510	0.57
332_G	367_D	0.510	0.57
395_F	399_T	0.509	0.57
266_A	287_V	0.509	0.57
210_S	320_N	0.509	0.57
82_T	86_N	0.509	0.57
40_L	178_I	0.508	0.56
209_N	316_K	0.508	0.56
213_L	319_T	0.507	0.56
366_T	377_I	0.507	0.56
171_V	424_V	0.506	0.56
164_A	196_S	0.506	0.56
261_P	264_T	0.505	0.56
273_I	287_V	0.505	0.56
248_D	464_I	0.505	0.56
312_V	517_S	0.505	0.56
32_A	316_K	0.505	0.56
213_L	317_I	0.505	0.56
134_H	175_S	0.504	0.56
99_T	163_I	0.503	0.56
299_V	419_V	0.503	0.56
491_I	498_T	0.502	0.56
172_V	468_F	0.502	0.56
301_H	414_T	0.502	0.56
128_Y	184_L	0.501	0.55
27_S	31_D	0.501	0.55
201_G	211_A	0.501	0.55
37_G	75_D	0.501	0.55
108_E	294_T	0.501	0.55
482_L	502_V	0.501	0.55
117_P	120_L	0.501	0.55
216_L	257_I	0.500	0.55
52_L	247_N	0.500	0.55
298_G	409_I	0.500	0.55
78_M	455_A	0.500	0.55
250_T	416_K	0.500	0.55

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3cetA	2	0.5595	100	0.736	Contact Map
3hz6A	1	0.8469	99.9	0.845	Contact Map
3ifrA	2	0.8318	99.9	0.851	Contact Map
2zf5O	3	0.828	99.6	0.904	Contact Map
2itmA	2	0.8091	99.5	0.91	Contact Map
2d4wA	2	0.845	99.5	0.911	Contact Map
4a2aA	1	0.6371	99.5	0.911	Contact Map
2dpnA	2	0.8242	99.4	0.915	Contact Map
3g25A	3	0.8318	99.3	0.917	Contact Map
3qdkA	2	0.8677	99.3	0.917	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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