GREMLIN Database
Q97XN9 - Uncharacterized protein
UniProt: Q97XN9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 128 (115)
Sequences: 460 (422)
Seq/√Len: 39.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
18_R117_K5.7541.00
11_E124_K4.7321.00
13_D39_K3.4551.00
57_S84_S2.6561.00
106_K110_E2.5651.00
40_A120_L2.5361.00
16_V20_L2.4461.00
20_L32_Y2.3781.00
86_H104_Y2.2831.00
79_D115_R2.2080.99
41_L58_L2.1630.99
9_Q27_F2.0670.99
28_A32_Y2.0350.99
44_L72_I1.7670.97
13_D32_Y1.7490.97
62_A80_L1.7280.97
44_L65_I1.6180.95
114_R117_K1.6080.95
7_M40_A1.5980.95
72_I122_W1.5480.94
26_Y109_A1.5290.94
37_V83_I1.5160.94
11_E120_L1.4860.93
9_Q104_Y1.4750.93
58_L80_L1.4450.92
86_H112_L1.4360.92
15_D25_K1.4340.92
12_E27_F1.4000.91
19_V25_K1.3970.90
85_P108_M1.3850.90
19_V23_A1.3150.88
113_Y117_K1.3070.87
36_A113_Y1.2420.84
33_S114_R1.2290.84
65_I72_I1.2220.83
16_V32_Y1.1640.80
48_L65_I1.1550.80
33_S116_A1.1510.79
16_V25_K1.1440.79
8_I102_R1.1430.79
105_T108_M1.1280.78
7_M43_S1.1110.77
39_K93_P1.1060.77
82_V111_D1.0950.76
10_A40_A1.0780.75
13_D20_L1.0690.74
17_A33_S1.0660.74
58_L84_S1.0650.74
16_V28_A1.0640.74
20_L28_A1.0570.73
121_G125_G1.0550.73
62_A72_I1.0470.73
76_I119_V1.0310.71
31_F87_F1.0280.71
117_K121_G1.0010.69
83_I116_A0.9860.68
114_R118_E0.9820.68
12_E20_L0.9600.66
76_I80_L0.9590.66
84_S87_F0.9470.65
30_T112_L0.9470.65
34_Q109_A0.9360.64
84_S89_I0.9350.64
21_L30_T0.9290.63
39_K54_K0.9240.63
79_D118_E0.9240.63
14_L116_A0.9200.63
21_L113_Y0.9190.62
21_L109_A0.9180.62
45_L108_M0.9000.61
86_H90_S0.8800.59
7_M124_K0.8700.58
18_R113_Y0.8640.58
37_V119_V0.8530.57
5_D32_Y0.8360.55
32_Y39_K0.8300.55
20_L39_K0.8290.55
5_D46_I0.8260.54
29_V109_A0.8210.54
14_L18_R0.8100.53
108_M112_L0.8020.52
12_E28_A0.7920.51
45_L61_L0.7900.51
110_E114_R0.7850.51
45_L65_I0.7840.50
34_Q86_H0.7780.50
108_M115_R0.7780.50
7_M120_L0.7760.50
44_L70_L0.7650.49
49_G84_S0.7630.49
104_Y112_L0.7620.48
36_A67_N0.7490.47
78_E107_N0.7450.47
62_A89_I0.7420.47
41_L55_T0.7370.46
13_D16_V0.7280.45
9_Q53_G0.7230.45
21_L106_K0.7210.45
12_E103_Q0.7210.45
62_A76_I0.7170.44
5_D55_T0.7170.44
42_K56_H0.7090.44
82_V112_L0.7060.43
31_F88_I0.7040.43
87_F90_S0.7030.43
23_A63_S0.7010.43
89_I94_D0.6910.42
15_D18_R0.6750.41
87_F95_A0.6660.40
33_S109_A0.6660.40
79_D82_V0.6630.40
17_A113_Y0.6620.39
55_T65_I0.6600.39
44_L78_E0.6600.39
113_Y120_L0.6580.39
31_F91_R0.6510.39
26_Y31_F0.6500.38
111_D114_R0.6420.38
84_S88_I0.6330.37
10_A93_P0.6290.37
6_W92_Y0.6290.37
14_L63_S0.6260.36
50_K64_M0.6240.36
18_R22_E0.6240.36
45_L64_M0.6230.36
30_T108_M0.6190.36
80_L84_S0.6190.36
44_L68_E0.6170.36
65_I122_W0.6160.36
58_L85_P0.6110.35
36_A120_L0.6100.35
9_Q101_A0.6100.35
13_D93_P0.6080.35
30_T90_S0.6070.35
10_A36_A0.6000.34
25_K28_A0.5920.34
32_Y45_L0.5890.33
25_K31_F0.5880.33
32_Y46_I0.5870.33
12_E25_K0.5870.33
37_V80_L0.5820.33
25_K32_Y0.5790.33
55_T89_I0.5770.32
26_Y29_V0.5770.32
84_S103_Q0.5760.32
75_N118_E0.5740.32
10_A78_E0.5730.32
41_L59_T0.5640.31
66_E72_I0.5580.31
86_H101_A0.5570.31
35_Q83_I0.5480.30
80_L119_V0.5470.30
35_Q116_A0.5430.30
12_E19_V0.5430.30
67_N75_N0.5370.29
34_Q87_F0.5310.29
39_K46_I0.5300.29
10_A85_P0.5290.29
44_L48_L0.5280.29
65_I70_L0.5270.29
6_W41_L0.5250.28
74_Q77_M0.5240.28
20_L61_L0.5230.28
11_E77_M0.5210.28
67_N71_K0.5150.28
114_R123_V0.5130.28
56_H61_L0.5120.27
48_L90_S0.5070.27
9_Q28_A0.5070.27
39_K51_D0.5040.27
27_F95_A0.5040.27
30_T87_F0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3o10A 2 0.9922 100 0.283 Contact Map
1ufbA 3 0.9766 100 0.284 Contact Map
1wolA 1 0.9375 100 0.315 Contact Map
1o3uA 2 0.9141 100 0.318 Contact Map
4nqfA 2 0.9531 100 0.35 Contact Map
2hsbA 2 0.9297 99.9 0.418 Contact Map
2jpuA 1 0.8828 87.2 0.88 Contact Map
3mfnA 2 0.9062 43.5 0.914 Contact Map
1knyA 2 0.8516 39.6 0.916 Contact Map
4wuyA 1 0.8828 26.3 0.924 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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