Q97XM1 - SULSO - GREMLIN Contacts

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Q97XM1 - Amine oxidase

UniProt:	Q97XM1	Sequences: MVEEEQVAISKSPLDPLNEEEIRKSVEVLKRQLNLDAKVVKFFSVELKEPKKQEYLEWRNNKNIKIERESLVKYYNFQDRKVYEAIISLDNNVVKEIRSIDAAYPPITLDEFGECEKAVRNDKRVQEALTKRGILINDLNLLMVDCWAPGHVDEELRGRRVAIGYMWVKKDIEDNGYGRPVHGLMPWVDLDKMEVIRIDDHGTSPLPLQDANYTPEKLGKIFGDDLKPIEIRQPLSSSIKINGWEISWYRWRLRIGYTPREGLVIYDVRYIDENNRERMILYRASVVDLMVPYGDPSPFHNKKMVLDAGDYGLGNFIVPLSHGNYDLYNCDCFGEVIYHLDVTRVSSNGTPIKIKKAICVHEEDFGVLWRHTDLRSGKSEVRRNRRLVVSFWATLANYDYGFFWYFYQDGSIEFLVKLTGIINDDSISEKDPTPKYGTRVTPEVYAPIHIHFFNIRLNINVDGLRNRIYEVNLRGEPITEKNPVGNAFFAEENLLENEADARRHVNPQTGRYWKIVNIQKKNYLGLPVAYRLVPGHNVLPPLPDDSYVRRRGAYINYHLWVTPYNEEERYASGDYPYLRANDGLPKYILKKRSIVDEDLVIWYTLGVEHVVRIEDWPVMPVEMAGFRLIPDGFFDKNPTIYLPRQLRINGQPLHREHKSH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	660 (620)
Sequences:	1325 (822)
Seq/√Len:	33.0

ECOLI - AMO
SULSO - Q97XM1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
496_E	595_V	5.986	1.00
519_Q	596_D	5.901	1.00
287_V	571_A	5.793	1.00
55_Y	282_Y	5.097	1.00
246_I	360_V	5.056	1.00
504_H	557_Y	4.737	1.00
516_V	529_A	4.561	1.00
340_L	360_V	4.511	1.00
563_P	597_E	4.274	1.00
346_S	350_T	3.997	1.00
253_L	389_V	3.856	1.00
268_V	406_F	3.830	1.00
389_V	406_F	3.824	1.00
467_R	494_L	3.738	1.00
246_I	340_L	3.638	1.00
247_S	252_R	3.635	1.00
465_R	597_E	3.604	1.00
241_I	246_I	3.562	1.00
474_R	491_E	3.547	1.00
562_T	602_W	3.472	1.00
281_L	459_I	3.395	1.00
56_L	282_Y	3.380	1.00
246_I	253_L	3.207	1.00
506_N	509_T	3.165	1.00
241_I	340_L	3.161	1.00
84_E	575_Y	3.151	1.00
25_S	70_S	2.821	1.00
497_N	594_I	2.801	1.00
279_M	460_N	2.793	1.00
467_R	596_D	2.788	1.00
496_E	500_D	2.766	1.00
342_V	357_A	2.753	1.00
67_E	88_S	2.702	1.00
245_E	252_R	2.649	1.00
360_V	387_L	2.645	1.00
518_I	595_V	2.632	1.00
517_N	528_V	2.599	1.00
52_K	598_D	2.581	1.00
613_I	632_G	2.563	1.00
470_E	503_R	2.553	1.00
225_D	249_Y	2.484	1.00
281_L	284_A	2.450	1.00
468_I	599_L	2.449	1.00
29_L	72_V	2.424	0.99
72_V	87_I	2.398	0.99
265_I	406_F	2.386	0.99
48_K	69_E	2.354	0.99
521_K	527_P	2.352	0.99
127_E	130_T	2.352	0.99
26_V	30_K	2.337	0.99
422_I	446_A	2.334	0.99
563_P	592_R	2.330	0.99
56_L	464_L	2.328	0.99
495_L	594_I	2.327	0.99
26_V	45_V	2.271	0.99
242_N	247_S	2.246	0.99
332_C	359_C	2.225	0.99
594_I	599_L	2.201	0.99
69_E	95_K	2.181	0.99
390_S	403_F	2.179	0.99
56_L	460_N	2.173	0.99
469_Y	494_L	2.163	0.99
249_Y	270_Y	2.159	0.99
467_R	516_V	2.139	0.99
23_R	351_P	2.130	0.99
122_D	195_V	2.098	0.98
265_I	389_V	2.094	0.98
17_L	70_S	2.084	0.98
14_L	55_Y	2.083	0.98
518_I	596_D	2.023	0.98
229_I	232_R	2.019	0.98
24_K	92_N	2.014	0.98
19_E	343_T	1.998	0.98
159_R	194_E	1.993	0.98
499_A	591_K	1.980	0.98
532_L	601_I	1.976	0.98
250_R	271_I	1.948	0.97
502_R	557_Y	1.940	0.97
565_N	592_R	1.938	0.97
51_K	566_E	1.935	0.97
253_L	406_F	1.927	0.97
69_E	86_I	1.922	0.97
473_L	610_V	1.919	0.97
88_S	91_N	1.893	0.97
384_N	407_Y	1.890	0.97
319_P	354_I	1.867	0.97
498_E	592_R	1.839	0.96
241_I	360_V	1.838	0.96
265_I	268_V	1.827	0.96
454_N	571_A	1.823	0.96
81_K	99_S	1.813	0.96
565_N	568_E	1.799	0.96
343_T	353_K	1.794	0.96
460_N	464_L	1.790	0.96
174_D	212_N	1.782	0.96
467_R	595_V	1.773	0.96
280_I	461_V	1.771	0.95
284_A	457_L	1.744	0.95
482_N	485_G	1.737	0.95
159_R	189_D	1.729	0.95
497_N	591_K	1.726	0.95
13_P	55_Y	1.724	0.95
70_S	89_L	1.721	0.95
532_L	559_L	1.711	0.95
468_I	561_V	1.709	0.95
125_V	166_M	1.687	0.94
523_Y	635_D	1.670	0.94
249_Y	408_Q	1.669	0.94
25_S	72_V	1.669	0.94
593_S	597_E	1.658	0.94
386_R	407_Y	1.641	0.93
520_K	528_V	1.634	0.93
469_Y	516_V	1.628	0.93
83_Y	97_I	1.623	0.93
568_E	590_K	1.622	0.93
437_G	445_Y	1.617	0.93
250_R	270_Y	1.616	0.93
117_K	121_N	1.612	0.93
478_I	543_P	1.608	0.92
71_L	575_Y	1.598	0.92
457_L	603_Y	1.594	0.92
15_D	243_G	1.592	0.92
268_V	281_L	1.581	0.92
233_Q	239_I	1.566	0.91
422_I	440_V	1.566	0.91
455_I	626_F	1.561	0.91
455_I	605_L	1.553	0.91
454_N	604_T	1.553	0.91
245_E	254_R	1.536	0.91
568_E	600_V	1.533	0.91
57_E	61_N	1.530	0.90
532_L	603_Y	1.521	0.90
470_E	493_N	1.497	0.89
200_D	204_S	1.496	0.89
29_L	42_F	1.488	0.89
67_E	90_D	1.485	0.89
123_K	127_E	1.476	0.89
302_K	399_D	1.475	0.89
367_V	381_V	1.464	0.88
365_F	623_M	1.457	0.88
241_I	337_I	1.443	0.88
124_R	127_E	1.434	0.87
368_L	642_L	1.432	0.87
363_E	386_R	1.431	0.87
407_Y	413_E	1.431	0.87
515_I	601_I	1.420	0.87
23_R	350_T	1.419	0.87
115_C	190_L	1.416	0.87
161_V	196_I	1.414	0.87
467_R	518_I	1.413	0.87
188_V	195_V	1.404	0.86
84_E	574_D	1.402	0.86
148_A	311_Y	1.400	0.86
16_P	244_W	1.398	0.86
155_E	197_R	1.390	0.86
254_R	266_Y	1.390	0.86
134_I	138_D	1.381	0.85
228_P	235_L	1.380	0.85
51_K	54_E	1.372	0.85
471_V	490_A	1.372	0.85
239_I	337_I	1.368	0.85
465_R	519_Q	1.367	0.85
502_R	588_I	1.364	0.84
162_A	190_L	1.350	0.84
233_Q	236_S	1.340	0.83
515_I	599_L	1.335	0.83
354_I	357_A	1.331	0.83
281_L	457_L	1.327	0.83
166_M	181_V	1.305	0.82
341_D	353_K	1.304	0.82
229_I	408_Q	1.304	0.82
282_Y	564_Y	1.301	0.82
240_K	247_S	1.294	0.81
471_V	514_K	1.294	0.81
581_N	585_P	1.289	0.81
252_R	269_R	1.287	0.81
52_K	282_Y	1.282	0.81
17_L	21_E	1.282	0.81
286_V	414_F	1.278	0.80
53_Q	57_E	1.273	0.80
54_E	67_E	1.271	0.80
294_G	448_I	1.269	0.80
476_E	489_F	1.267	0.80
495_L	501_A	1.266	0.80
48_K	86_I	1.264	0.80
603_Y	626_F	1.263	0.80
499_A	502_R	1.243	0.78
320_L	332_C	1.242	0.78
17_L	47_L	1.241	0.78
322_H	336_V	1.238	0.78
52_K	56_L	1.238	0.78
242_N	245_E	1.214	0.77
369_W	380_E	1.214	0.77
414_F	626_F	1.212	0.77
127_E	131_K	1.210	0.77
565_N	590_K	1.207	0.76
535_G	603_Y	1.205	0.76
303_K	423_N	1.197	0.76
498_E	568_E	1.197	0.76
472_N	511_R	1.196	0.76
71_L	84_E	1.194	0.76
27_E	31_R	1.190	0.75
249_Y	641_Y	1.187	0.75
438_T	446_A	1.180	0.75
472_N	515_I	1.179	0.75
85_A	97_I	1.175	0.74
144_V	166_M	1.172	0.74
123_K	126_Q	1.168	0.74
386_R	405_Y	1.165	0.74
342_V	358_I	1.164	0.74
425_D	447_P	1.162	0.74
497_N	500_D	1.158	0.73
129_L	142_L	1.152	0.73
427_I	430_K	1.138	0.72
114_E	193_M	1.135	0.72
367_V	392_W	1.134	0.72
463_G	466_N	1.128	0.71
258_T	264_V	1.127	0.71
532_L	628_L	1.127	0.71
52_K	460_N	1.126	0.71
222_F	644_R	1.125	0.71
408_Q	642_L	1.115	0.70
517_N	596_D	1.109	0.70
440_V	444_V	1.106	0.70
83_Y	99_S	1.101	0.69
80_R	83_Y	1.101	0.69
457_L	628_L	1.100	0.69
364_D	383_R	1.092	0.69
473_L	488_F	1.092	0.69
61_N	64_I	1.091	0.69
305_V	399_D	1.088	0.68
529_A	599_L	1.087	0.68
70_S	87_I	1.085	0.68
268_V	284_A	1.082	0.68
78_Q	280_I	1.080	0.68
336_V	361_H	1.080	0.68
607_V	610_V	1.077	0.68
392_W	399_D	1.076	0.68
333_F	336_V	1.075	0.68
118_A	192_K	1.072	0.67
144_V	164_G	1.071	0.67
177_Y	213_Y	1.068	0.67
476_E	487_A	1.067	0.67
341_D	357_A	1.066	0.67
563_P	594_I	1.066	0.67
86_I	95_K	1.065	0.67
369_W	637_N	1.063	0.67
498_E	591_K	1.060	0.66
179_R	206_L	1.057	0.66
56_L	279_M	1.057	0.66
425_D	445_Y	1.057	0.66
563_P	593_S	1.056	0.66
282_Y	460_N	1.055	0.66
110_D	114_E	1.053	0.66
240_K	321_S	1.051	0.66
59_R	62_K	1.048	0.66
549_R	556_N	1.046	0.65
111_E	160_R	1.043	0.65
128_A	132_R	1.042	0.65
413_E	627_R	1.039	0.65
96_E	461_V	1.025	0.64
31_R	92_N	1.024	0.64
339_H	359_C	1.020	0.63
114_E	117_K	1.019	0.63
609_H	615_D	1.016	0.63
116_E	375_R	1.015	0.63
222_F	225_D	1.013	0.63
226_L	249_Y	1.013	0.63
321_S	355_K	1.011	0.63
344_R	352_I	1.010	0.63
227_K	235_L	1.010	0.63
337_I	340_L	1.008	0.62
517_N	529_A	1.007	0.62
330_C	334_G	1.007	0.62
418_L	607_V	1.005	0.62
467_R	517_N	1.005	0.62
462_D	528_V	1.000	0.62
58_W	65_K	0.998	0.62
361_H	390_S	0.994	0.61
474_R	489_F	0.990	0.61
540_P	555_I	0.988	0.61
340_L	387_L	0.988	0.61
452_F	540_P	0.987	0.61
285_S	456_R	0.983	0.60
582_D	586_K	0.982	0.60
116_E	255_I	0.982	0.60
27_E	92_N	0.982	0.60
230_E	647_R	0.981	0.60
333_F	361_H	0.980	0.60
171_D	174_D	0.979	0.60
360_V	365_F	0.978	0.60
223_G	641_Y	0.977	0.60
47_L	68_R	0.974	0.60
225_D	250_R	0.974	0.60
424_D	616_W	0.972	0.60
419_T	544_D	0.965	0.59
187_W	199_D	0.964	0.59
28_V	88_S	0.964	0.59
290_M	552_G	0.961	0.59
495_L	502_R	0.961	0.59
147_W	305_V	0.960	0.59
227_K	238_S	0.958	0.58
587_Y	590_K	0.957	0.58
213_Y	454_N	0.954	0.58
448_I	489_F	0.951	0.58
16_P	256_G	0.951	0.58
351_P	640_I	0.949	0.58
29_L	85_A	0.944	0.57
86_I	412_I	0.942	0.57
344_R	354_I	0.938	0.57
20_E	294_G	0.931	0.56
301_N	484_V	0.931	0.56
256_G	264_V	0.928	0.56
582_D	585_P	0.926	0.56
233_Q	237_S	0.925	0.56
86_I	567_E	0.923	0.56
194_E	242_N	0.923	0.56
365_F	386_R	0.922	0.56
529_A	632_G	0.922	0.56
478_I	545_D	0.921	0.55
282_Y	464_L	0.918	0.55
48_K	246_I	0.917	0.55
352_I	529_A	0.916	0.55
499_A	588_I	0.910	0.55
368_L	408_Q	0.910	0.55
501_A	599_L	0.909	0.54
554_Y	572_S	0.900	0.54
18_N	575_Y	0.900	0.54
54_E	57_E	0.899	0.54
54_E	66_I	0.898	0.54
54_E	69_E	0.898	0.54
24_K	28_V	0.897	0.53
48_K	71_L	0.896	0.53
343_T	351_P	0.894	0.53
496_E	599_L	0.892	0.53
608_E	622_E	0.890	0.53
306_L	554_Y	0.888	0.53
517_N	520_K	0.882	0.52
427_I	434_P	0.880	0.52
422_I	444_V	0.877	0.52
70_S	632_G	0.877	0.52
519_Q	597_E	0.877	0.52
127_E	496_E	0.875	0.52
369_W	382_R	0.873	0.51
214_T	217_K	0.873	0.51
284_A	412_I	0.872	0.51
319_P	357_A	0.872	0.51
54_E	65_K	0.871	0.51
496_E	596_D	0.871	0.51
361_H	403_F	0.871	0.51
542_L	555_I	0.870	0.51
28_V	70_S	0.870	0.51
336_V	370_R	0.869	0.51
251_W	602_W	0.868	0.51
457_L	601_I	0.866	0.51
308_A	313_L	0.864	0.51
396_A	488_F	0.864	0.51
544_D	549_R	0.863	0.51
18_N	21_E	0.862	0.51
71_L	86_I	0.860	0.50
607_V	622_E	0.855	0.50
21_E	68_R	0.854	0.50
257_Y	317_I	0.854	0.50
226_L	238_S	0.852	0.50
620_P	633_F	0.848	0.49
488_F	608_E	0.845	0.49
102_A	105_P	0.844	0.49
251_W	562_T	0.843	0.49
126_Q	130_T	0.840	0.49
461_V	599_L	0.837	0.48
114_E	559_L	0.836	0.48
444_V	616_W	0.836	0.48
584_L	588_I	0.835	0.48
126_Q	139_L	0.835	0.48
229_I	238_S	0.834	0.48
477_P	489_F	0.833	0.48
472_N	493_N	0.831	0.48
14_L	229_I	0.830	0.48
20_E	23_R	0.830	0.48
11_K	18_N	0.829	0.48
360_V	406_F	0.829	0.48
17_L	89_L	0.828	0.48
131_K	200_D	0.828	0.48
29_L	575_Y	0.827	0.48
401_G	419_T	0.824	0.47
50_P	68_R	0.821	0.47
60_N	66_I	0.819	0.47
253_L	563_P	0.819	0.47
88_S	95_K	0.818	0.47
55_Y	196_I	0.817	0.47
331_D	370_R	0.815	0.47
353_K	589_L	0.815	0.47
208_L	253_L	0.815	0.47
117_K	130_T	0.815	0.47
534_P	603_Y	0.814	0.47
527_P	544_D	0.814	0.47
334_G	339_H	0.814	0.47
553_A	556_N	0.813	0.46
145_D	375_R	0.813	0.46
55_Y	266_Y	0.812	0.46
105_P	111_E	0.809	0.46
244_W	507_P	0.808	0.46
119_V	188_V	0.808	0.46
609_H	617_P	0.808	0.46
87_I	595_V	0.807	0.46
594_I	597_E	0.806	0.46
363_E	390_S	0.805	0.46
494_L	516_V	0.805	0.46
58_W	62_K	0.804	0.46
58_W	264_V	0.803	0.46
290_M	304_M	0.803	0.46
128_A	131_K	0.802	0.46
334_G	361_H	0.802	0.46
154_E	601_I	0.800	0.45
332_C	339_H	0.798	0.45
147_W	177_Y	0.796	0.45
29_L	45_V	0.794	0.45
330_C	361_H	0.793	0.45
87_I	480_E	0.793	0.45
12_S	254_R	0.790	0.45
116_E	374_L	0.788	0.44
166_M	186_P	0.784	0.44
401_G	417_K	0.783	0.44
317_I	391_F	0.781	0.44
538_V	541_P	0.778	0.44
167_W	424_D	0.778	0.44
476_E	543_P	0.777	0.43
84_E	98_R	0.776	0.43
452_F	604_T	0.774	0.43
318_V	370_R	0.774	0.43
563_P	588_I	0.772	0.43
105_P	110_D	0.771	0.43
270_Y	280_I	0.770	0.43
460_N	598_D	0.768	0.43
225_D	643_P	0.766	0.43
73_K	105_P	0.766	0.43
104_Y	358_I	0.765	0.43
52_K	599_L	0.762	0.42
403_F	415_L	0.761	0.42
633_F	637_N	0.761	0.42
224_D	242_N	0.760	0.42
488_F	548_V	0.760	0.42
209_Q	523_Y	0.758	0.42
496_E	518_I	0.756	0.42
450_I	608_E	0.755	0.42
356_K	463_G	0.753	0.42
312_G	339_H	0.752	0.41
494_L	595_V	0.752	0.41
461_V	550_R	0.752	0.41
130_T	134_I	0.752	0.41
390_S	401_G	0.751	0.41
149_P	153_D	0.750	0.41
438_T	448_I	0.750	0.41
95_K	101_D	0.750	0.41
469_Y	492_E	0.749	0.41
174_D	390_S	0.748	0.41
115_C	226_L	0.748	0.41
256_G	515_I	0.747	0.41
110_D	347_S	0.747	0.41
147_W	375_R	0.746	0.41
145_D	177_Y	0.745	0.41
195_V	591_K	0.743	0.41
553_A	585_P	0.741	0.41
109_L	393_A	0.740	0.40
305_V	531_R	0.739	0.40
231_I	440_V	0.739	0.40
402_F	559_L	0.736	0.40
514_K	529_A	0.734	0.40
562_T	568_E	0.734	0.40
305_V	375_R	0.732	0.40
144_V	162_A	0.730	0.40
59_R	66_I	0.730	0.40
150_G	349_G	0.730	0.40
58_W	244_W	0.729	0.40
125_V	184_L	0.729	0.40
124_R	198_I	0.728	0.40
127_E	134_I	0.728	0.40
20_E	98_R	0.727	0.39
246_I	255_I	0.726	0.39
370_R	450_I	0.725	0.39
391_F	402_F	0.725	0.39
29_L	87_I	0.724	0.39
237_S	335_E	0.724	0.39
181_V	422_I	0.722	0.39
557_Y	589_L	0.721	0.39
10_S	491_E	0.720	0.39
330_C	336_V	0.720	0.39
12_S	15_D	0.719	0.39
598_D	615_D	0.716	0.39
130_T	247_S	0.715	0.39
412_I	501_A	0.710	0.38
28_V	31_R	0.710	0.38
392_W	401_G	0.709	0.38
14_L	267_D	0.707	0.38
398_Y	449_H	0.707	0.38
202_G	206_L	0.705	0.38
333_F	390_S	0.705	0.38
52_K	466_N	0.705	0.38
350_T	589_L	0.704	0.38
270_Y	641_Y	0.704	0.38
305_V	396_A	0.703	0.38
215_P	378_K	0.703	0.38
209_Q	570_Y	0.702	0.37
24_K	27_E	0.702	0.37
461_V	519_Q	0.701	0.37
75_Y	191_D	0.700	0.37
42_F	575_Y	0.700	0.37
26_V	77_F	0.700	0.37
477_P	485_G	0.699	0.37
402_F	534_P	0.698	0.37
606_G	609_H	0.698	0.37
320_L	359_C	0.696	0.37
154_E	157_R	0.695	0.37
295_D	447_P	0.695	0.37
448_I	611_V	0.694	0.37
518_I	529_A	0.694	0.37
470_E	495_L	0.693	0.37
59_R	481_K	0.691	0.37
190_L	396_A	0.691	0.37
287_V	454_N	0.690	0.37
467_R	492_E	0.690	0.37
322_H	356_K	0.689	0.36
441_T	572_S	0.687	0.36
42_F	47_L	0.685	0.36
229_I	249_Y	0.685	0.36
268_V	459_I	0.685	0.36
556_N	585_P	0.684	0.36
220_K	484_V	0.684	0.36
510_G	538_V	0.682	0.36
384_N	408_Q	0.682	0.36
318_V	322_H	0.682	0.36
55_Y	267_D	0.681	0.36
501_A	594_I	0.681	0.36
568_E	592_R	0.681	0.36
538_V	542_L	0.680	0.36
466_N	517_N	0.680	0.36
66_I	610_V	0.679	0.36
121_N	126_Q	0.676	0.35
442_P	454_N	0.675	0.35
198_I	495_L	0.675	0.35
48_K	567_E	0.674	0.35
74_Y	85_A	0.674	0.35
284_A	404_W	0.673	0.35
150_G	551_R	0.672	0.35
32_Q	268_V	0.672	0.35
145_D	305_V	0.671	0.35
11_K	32_Q	0.671	0.35
286_V	455_I	0.670	0.35
330_C	364_D	0.670	0.35
365_F	384_N	0.669	0.35
227_K	231_I	0.668	0.35
336_V	390_S	0.667	0.35
216_E	220_K	0.667	0.35
542_L	608_E	0.667	0.35
123_K	195_V	0.666	0.35
602_W	630_P	0.666	0.35
30_K	559_L	0.664	0.35
397_N	400_Y	0.664	0.35
176_G	375_R	0.663	0.34
395_L	500_D	0.662	0.34
238_S	385_R	0.662	0.34
119_V	126_Q	0.662	0.34
454_N	602_W	0.661	0.34
374_L	422_I	0.660	0.34
273_E	528_V	0.660	0.34
53_Q	93_V	0.660	0.34
557_Y	560_W	0.659	0.34
196_I	435_K	0.659	0.34
454_N	624_A	0.657	0.34
527_P	640_I	0.656	0.34
470_E	513_W	0.656	0.34
333_F	460_N	0.655	0.34
250_R	641_Y	0.655	0.34
466_N	599_L	0.654	0.34
637_N	642_L	0.654	0.34
235_L	250_R	0.654	0.34
517_N	521_K	0.654	0.34
465_R	518_I	0.653	0.34
594_I	598_D	0.653	0.34
568_E	582_D	0.653	0.34
218_L	461_V	0.651	0.34
409_D	639_T	0.649	0.33
483_P	522_N	0.648	0.33
457_L	592_R	0.647	0.33
115_C	162_A	0.645	0.33
196_I	524_L	0.643	0.33
30_K	246_I	0.643	0.33
466_N	598_D	0.643	0.33
29_L	202_G	0.642	0.33
561_V	601_I	0.640	0.33
270_Y	294_G	0.640	0.33
40_V	597_E	0.640	0.33
188_V	360_V	0.640	0.33
614_E	617_P	0.640	0.33
465_R	496_E	0.637	0.33
228_P	475_G	0.637	0.33
172_I	271_I	0.637	0.33
117_K	124_R	0.636	0.32
563_P	569_R	0.636	0.32
381_V	510_G	0.636	0.32
70_S	384_N	0.635	0.32
404_W	603_Y	0.634	0.32
418_L	553_A	0.634	0.32
311_Y	396_A	0.633	0.32
165_Y	486_N	0.631	0.32
231_I	408_Q	0.631	0.32
154_E	162_A	0.630	0.32
430_K	433_T	0.630	0.32
255_I	296_P	0.629	0.32
76_N	80_R	0.628	0.32
36_D	40_V	0.628	0.32
134_I	142_L	0.628	0.32
69_E	72_V	0.626	0.32
76_N	79_D	0.626	0.32
503_R	513_W	0.626	0.32
620_P	638_P	0.625	0.32
376_S	436_Y	0.625	0.32
232_R	406_F	0.624	0.32
27_E	589_L	0.623	0.32
465_R	594_I	0.623	0.32
261_E	334_G	0.622	0.31
128_A	134_I	0.622	0.31
28_V	89_L	0.622	0.31
46_E	259_P	0.621	0.31
461_V	464_L	0.621	0.31
489_F	550_R	0.620	0.31
300_H	423_N	0.619	0.31
184_L	198_I	0.618	0.31
507_P	558_H	0.617	0.31
22_I	92_N	0.615	0.31
82_V	571_A	0.615	0.31
406_F	497_N	0.614	0.31
62_K	66_I	0.614	0.31
502_R	584_L	0.614	0.31
163_I	305_V	0.614	0.31
283_R	334_G	0.613	0.31
26_V	346_S	0.613	0.31
211_A	444_V	0.613	0.31
184_L	305_V	0.613	0.31
433_T	521_K	0.612	0.31
132_R	280_I	0.612	0.31
245_E	360_V	0.612	0.31
456_R	612_R	0.611	0.31
73_K	84_E	0.611	0.31
459_I	626_F	0.611	0.31
58_W	624_A	0.610	0.31
427_I	439_R	0.610	0.31
290_M	468_I	0.610	0.31
115_C	188_V	0.610	0.31
13_P	349_G	0.610	0.31
556_N	559_L	0.609	0.31
86_I	101_D	0.609	0.31
86_I	96_E	0.608	0.30
131_K	203_T	0.608	0.30
298_P	301_N	0.608	0.30
246_I	496_E	0.608	0.30
291_V	573_G	0.607	0.30
166_M	436_Y	0.604	0.30
570_Y	633_F	0.604	0.30
499_A	564_Y	0.603	0.30
403_F	417_K	0.602	0.30
363_E	403_F	0.602	0.30
205_P	208_L	0.602	0.30
472_N	491_E	0.601	0.30
348_N	516_V	0.601	0.30
150_G	493_N	0.600	0.30
107_I	117_K	0.600	0.30
450_I	511_R	0.598	0.30
20_E	57_E	0.598	0.30
290_M	373_D	0.597	0.30
115_C	144_V	0.596	0.30
356_K	642_L	0.596	0.30
107_I	162_A	0.596	0.30
255_I	570_Y	0.595	0.30
31_R	35_L	0.593	0.29
130_T	137_N	0.593	0.29
39_V	267_D	0.592	0.29
112_F	120_R	0.591	0.29
257_Y	455_I	0.591	0.29
335_E	515_I	0.591	0.29
43_F	108_T	0.590	0.29
521_K	528_V	0.588	0.29
91_N	265_I	0.587	0.29
628_L	634_F	0.587	0.29
472_N	527_P	0.587	0.29
22_I	243_G	0.586	0.29
66_I	465_R	0.586	0.29
13_P	47_L	0.586	0.29
211_A	616_W	0.586	0.29
55_Y	60_N	0.585	0.29
305_V	361_H	0.585	0.29
504_H	558_H	0.585	0.29
253_L	494_L	0.585	0.29
495_L	500_D	0.585	0.29
633_F	638_P	0.585	0.29
322_H	370_R	0.584	0.29
313_L	455_I	0.584	0.29
560_W	573_G	0.584	0.29
568_E	598_D	0.583	0.29
58_W	61_N	0.583	0.29
392_W	515_I	0.582	0.29
488_F	610_V	0.582	0.29
10_S	54_E	0.581	0.29
348_N	406_F	0.581	0.29
602_W	628_L	0.581	0.29
363_E	373_D	0.580	0.29
66_I	70_S	0.580	0.29
261_E	361_H	0.579	0.28
186_P	199_D	0.578	0.28
498_E	562_T	0.578	0.28
612_R	615_D	0.578	0.28
461_V	521_K	0.577	0.28
292_P	573_G	0.577	0.28
247_S	529_A	0.577	0.28
57_E	67_E	0.576	0.28
318_V	336_V	0.574	0.28
148_A	358_I	0.572	0.28
361_H	364_D	0.572	0.28
318_V	372_T	0.571	0.28
15_D	254_R	0.571	0.28
333_F	403_F	0.571	0.28
96_E	124_R	0.571	0.28
58_W	66_I	0.570	0.28
129_L	184_L	0.570	0.28
422_I	582_D	0.570	0.28
10_S	60_N	0.569	0.28
29_L	39_V	0.568	0.28
495_L	503_R	0.568	0.28
296_P	303_K	0.566	0.28
517_N	594_I	0.566	0.28
121_N	358_I	0.566	0.28
121_N	590_K	0.566	0.28
339_H	361_H	0.566	0.28
300_H	425_D	0.565	0.28
177_Y	375_R	0.565	0.28
236_S	239_I	0.565	0.28
253_L	268_V	0.565	0.28
336_V	399_D	0.565	0.28
253_L	280_I	0.565	0.28
316_F	395_L	0.563	0.27
45_V	536_H	0.563	0.27
565_N	569_R	0.563	0.27
330_C	339_H	0.563	0.27
381_V	601_I	0.562	0.27
495_L	511_R	0.562	0.27
267_D	566_E	0.561	0.27
86_I	210_D	0.558	0.27
369_W	573_G	0.558	0.27
87_I	492_E	0.557	0.27
14_L	260_R	0.557	0.27
134_I	421_I	0.556	0.27
289_L	370_R	0.556	0.27
523_Y	594_I	0.556	0.27
30_K	346_S	0.554	0.27
29_L	518_I	0.554	0.27
390_S	405_Y	0.554	0.27
45_V	280_I	0.553	0.27
46_E	258_T	0.552	0.27
133_G	139_L	0.552	0.27
200_D	207_P	0.552	0.27
413_E	625_G	0.551	0.27
238_S	330_C	0.551	0.27
213_Y	233_Q	0.551	0.27
280_I	646_L	0.551	0.27
404_W	457_L	0.551	0.27
497_N	563_P	0.550	0.27
119_V	164_G	0.550	0.27
255_I	263_L	0.549	0.26
124_R	194_E	0.549	0.26
92_N	350_T	0.549	0.26
280_I	641_Y	0.549	0.26
269_R	279_M	0.548	0.26
105_P	108_T	0.548	0.26
32_Q	67_E	0.548	0.26
251_W	630_P	0.548	0.26
92_N	465_R	0.548	0.26
113_G	117_K	0.547	0.26
422_I	437_G	0.547	0.26
51_K	87_I	0.547	0.26
239_I	636_K	0.546	0.26
268_V	499_A	0.546	0.26
311_Y	423_N	0.546	0.26
537_N	540_P	0.546	0.26
155_E	237_S	0.546	0.26
94_V	349_G	0.546	0.26
564_Y	569_R	0.546	0.26
225_D	642_L	0.545	0.26
78_Q	242_N	0.545	0.26
473_L	541_P	0.545	0.26
435_K	494_L	0.545	0.26
28_V	72_V	0.545	0.26
364_D	385_R	0.545	0.26
322_H	339_H	0.544	0.26
152_V	281_L	0.544	0.26
461_V	601_I	0.544	0.26
436_Y	448_I	0.544	0.26
89_L	465_R	0.543	0.26
205_P	407_Y	0.542	0.26
74_Y	267_D	0.542	0.26
280_I	342_V	0.542	0.26
20_E	465_R	0.542	0.26
526_L	529_A	0.541	0.26
292_P	551_R	0.541	0.26
193_M	452_F	0.541	0.26
51_K	564_Y	0.541	0.26
500_D	590_K	0.540	0.26
355_K	395_L	0.540	0.26
109_L	344_R	0.539	0.26
539_L	558_H	0.539	0.26
211_A	640_I	0.539	0.26
192_K	596_D	0.538	0.26
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161_V	389_V	0.538	0.26
89_L	131_K	0.538	0.26
188_V	296_P	0.535	0.26
498_E	590_K	0.535	0.26
320_L	339_H	0.534	0.26
137_N	140_N	0.533	0.25
461_V	598_D	0.533	0.25
568_E	639_T	0.533	0.25
125_V	129_L	0.532	0.25
526_L	632_G	0.531	0.25
330_C	383_R	0.531	0.25
193_M	240_K	0.530	0.25
181_V	528_V	0.530	0.25
176_G	212_N	0.530	0.25
212_N	215_P	0.530	0.25
500_D	591_K	0.530	0.25
568_E	586_K	0.529	0.25
122_D	125_V	0.529	0.25
330_C	333_F	0.529	0.25
244_W	301_N	0.528	0.25
498_E	565_N	0.528	0.25
57_E	480_E	0.528	0.25
468_I	532_L	0.527	0.25
51_K	55_Y	0.527	0.25
177_Y	373_D	0.527	0.25
15_D	255_I	0.527	0.25
55_Y	597_E	0.526	0.25
307_D	362_E	0.526	0.25
364_D	409_D	0.526	0.25
204_S	207_P	0.526	0.25
454_N	460_N	0.526	0.25
268_V	280_I	0.525	0.25
281_L	461_V	0.524	0.25
512_Y	531_R	0.524	0.25
505_V	603_Y	0.524	0.25
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150_G	310_D	0.523	0.25
412_I	455_I	0.522	0.25
123_K	240_K	0.522	0.25
117_K	412_I	0.522	0.25
267_D	272_D	0.521	0.25
239_I	265_I	0.521	0.25
472_N	509_T	0.521	0.25
222_F	475_G	0.521	0.25
157_R	579_R	0.521	0.25
18_N	92_N	0.520	0.25
242_N	545_D	0.520	0.25
549_R	553_A	0.520	0.25
110_D	113_G	0.519	0.25
118_A	188_V	0.519	0.25
497_N	596_D	0.519	0.25
342_V	351_P	0.519	0.25
497_N	519_Q	0.519	0.25
468_I	601_I	0.519	0.25
175_N	312_G	0.518	0.25
287_V	590_K	0.518	0.25
37_A	72_V	0.518	0.25
92_N	242_N	0.518	0.25
64_I	226_L	0.517	0.24
494_L	596_D	0.517	0.24
456_R	642_L	0.517	0.24
266_Y	546_S	0.516	0.24
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413_E	623_M	0.516	0.24
603_Y	628_L	0.516	0.24
68_R	388_V	0.515	0.24
203_T	206_L	0.515	0.24
118_A	198_I	0.514	0.24
386_R	390_S	0.513	0.24
396_A	525_G	0.513	0.24
461_V	559_L	0.513	0.24
18_N	599_L	0.513	0.24
336_V	417_K	0.512	0.24
334_G	364_D	0.512	0.24
460_N	568_E	0.512	0.24
58_W	90_D	0.511	0.24
465_R	596_D	0.510	0.24
497_N	593_S	0.510	0.24
636_K	640_I	0.510	0.24
418_L	422_I	0.509	0.24
80_R	191_D	0.509	0.24
39_V	78_Q	0.509	0.24
253_L	384_N	0.508	0.24
139_L	154_E	0.508	0.24
256_G	404_W	0.508	0.24
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261_E	306_L	0.507	0.24
11_K	92_N	0.507	0.24
242_N	525_G	0.507	0.24
514_K	631_D	0.507	0.24
128_A	133_G	0.507	0.24
596_D	599_L	0.506	0.24
194_E	461_V	0.506	0.24
506_N	532_L	0.506	0.24
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620_P	628_L	0.506	0.24
221_I	564_Y	0.505	0.24
249_Y	576_P	0.505	0.24
188_V	436_Y	0.505	0.24
33_L	37_A	0.504	0.24
347_S	529_A	0.504	0.24
497_N	509_T	0.504	0.24
352_I	596_D	0.503	0.24
291_V	448_I	0.503	0.24
616_W	619_M	0.503	0.24
184_L	346_S	0.503	0.24
265_I	506_N	0.503	0.24
500_D	594_I	0.502	0.24
75_Y	82_V	0.502	0.24
251_W	634_F	0.502	0.24
567_E	592_R	0.502	0.24
380_E	644_R	0.502	0.24
580_A	599_L	0.501	0.23
14_L	558_H	0.501	0.23
249_Y	456_R	0.501	0.23
311_Y	316_F	0.501	0.23
89_L	95_K	0.501	0.23
563_P	587_Y	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3sxxA	5	0.9742	100	0.117	Contact Map
3wa2X	2	0.9288	100	0.13	Contact Map
1ksiA	2	0.9485	100	0.137	Contact Map
1spuA	2	0.947	100	0.144	Contact Map
3loyA	2	0.9258	100	0.154	Contact Map
1tu5A	2	0.8682	100	0.179	Contact Map
3hi7A	2	0.947	100	0.19	Contact Map
3pgbA	2	0.9515	100	0.199	Contact Map
1w7cA	2	0.9652	100	0.204	Contact Map
1e29A	1	0.0682	29.1	0.986	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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