GREMLIN Database
Q97X90 - Uncharacterized protein
UniProt: Q97X90 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 143 (132)
Sequences: 19669 (15789)
Seq/√Len: 1374.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
35_T87_V3.1561.00
5_N35_T2.8291.00
7_V106_A2.7941.00
94_A130_R2.7431.00
33_K85_E2.6811.00
22_V140_L2.6261.00
5_N33_K2.4291.00
108_L140_L2.3831.00
87_V100_Y2.2391.00
109_I137_I2.0071.00
111_T131_I2.0001.00
91_G96_A1.9581.00
129_S133_H1.9441.00
35_T85_E1.9051.00
100_Y104_T1.8971.00
35_T106_A1.8711.00
73_K86_A1.8431.00
101_A109_I1.8341.00
35_T100_Y1.8331.00
33_K83_N1.7781.00
89_I96_A1.7721.00
35_T104_T1.7441.00
37_I100_Y1.7191.00
39_V96_A1.7121.00
9_A111_T1.6871.00
21_D75_K1.6571.00
8_V23_A1.6521.00
26_L30_Y1.5941.00
9_A97_I1.5891.00
5_N107_D1.5561.00
96_A99_D1.5561.00
38_E65_A1.5281.00
73_K77_V1.4951.00
17_K75_K1.4061.00
98_M134_E1.3941.00
32_A107_D1.3901.00
130_R134_E1.3871.00
66_K70_E1.3831.00
62_Y66_K1.3741.00
109_I135_A1.3531.00
89_I100_Y1.3521.00
8_V20_L1.3431.00
23_A27_A1.3411.00
101_A136_K1.2911.00
109_I131_I1.2501.00
37_I89_I1.2021.00
135_A139_V1.1811.00
93_P127_V1.1761.00
70_E73_K1.1491.00
65_A68_D1.1351.00
113_S141_V1.1111.00
68_D72_A1.1081.00
119_V123_F1.0991.00
39_V93_P1.0901.00
101_A137_I1.0861.00
121_R129_S1.0611.00
65_A69_V1.0371.00
10_Y72_A1.0371.00
22_V26_L1.0261.00
6_I108_L1.0071.00
111_T128_S0.9901.00
25_D29_R0.9861.00
101_A106_A0.9651.00
70_E86_A0.9651.00
70_E74_E0.9651.00
132_V141_V0.9551.00
98_M101_A0.9471.00
16_A19_A0.9461.00
20_L36_I0.9431.00
69_V86_A0.9371.00
12_G38_E0.9311.00
37_I97_I0.9241.00
58_I62_Y0.9231.00
17_K71_E0.9211.00
5_N106_A0.9201.00
38_E68_D0.9201.00
87_V104_T0.9141.00
5_N104_T0.9111.00
22_V25_D0.9101.00
30_Y107_D0.8941.00
59_N63_N0.8871.00
63_N67_R0.8841.00
40_I90_E0.8691.00
22_V138_P0.8661.00
13_S16_A0.8651.00
100_Y106_A0.8621.00
23_A110_V0.8591.00
40_I88_N0.8591.00
20_L72_A0.8571.00
61_M64_K0.8541.00
128_S141_V0.8541.00
116_L120_K0.8521.00
68_D71_E0.8511.00
10_Y19_A0.8311.00
22_V142_V0.8141.00
113_S128_S0.8141.00
36_I84_V0.8131.00
53_I56_E0.8091.00
63_N66_K0.8061.00
54_P57_V0.8051.00
28_K80_G0.8011.00
72_A75_K0.7931.00
75_K78_N0.7921.00
98_M131_I0.7891.00
67_R71_E0.7871.00
7_V109_I0.7821.00
71_E75_K0.7781.00
24_I79_S0.7761.00
24_I76_A0.7731.00
23_A34_L0.7701.00
10_Y36_I0.7691.00
20_L24_I0.7651.00
92_D95_A0.7591.00
10_Y20_L0.7551.00
27_A34_L0.7551.00
36_I72_A0.7531.00
110_V140_L0.7511.00
9_A112_G0.7481.00
118_T121_R0.7371.00
7_V37_I0.7301.00
13_S115_G0.7281.00
98_M135_A0.7271.00
65_A88_N0.7221.00
77_V80_G0.7211.00
71_E74_E0.7131.00
18_R21_D0.7121.00
60_E64_K0.7121.00
119_V122_I0.7091.00
28_K79_S0.7081.00
72_A76_A0.7041.00
10_Y17_K0.7011.00
75_K79_S0.6941.00
97_I131_I0.6941.00
64_K67_R0.6931.00
55_G59_N0.6891.00
62_Y90_E0.6891.00
17_K21_D0.6881.00
26_L29_R0.6871.00
74_E78_N0.6841.00
27_A32_A0.6821.00
8_V34_L0.6741.00
74_E77_V0.6721.00
40_I65_A0.6681.00
56_E60_E0.6651.00
27_A30_Y0.6581.00
61_M65_A0.6571.00
118_T122_I0.6551.00
69_V73_K0.6531.00
64_K68_D0.6501.00
115_G124_L0.6491.00
7_V100_Y0.6491.00
25_D28_K0.6461.00
17_K72_A0.6451.00
60_E63_N0.6391.00
124_L128_S0.6361.00
110_V142_V0.6361.00
105_G137_I0.6341.00
57_V60_E0.6291.00
96_A100_Y0.6271.00
36_I76_A0.6261.00
10_Y16_A0.6181.00
52_P56_E0.6151.00
66_K86_A0.6151.00
76_A79_S0.6121.00
94_A127_V0.6071.00
24_I81_V0.5991.00
12_G68_D0.5991.00
6_I110_V0.5981.00
73_K84_V0.5971.00
111_T141_V0.5961.00
76_A84_V0.5891.00
76_A80_G0.5861.00
94_A98_M0.5821.00
37_I96_A0.5811.00
24_I28_K0.5651.00
23_A32_A0.5611.00
55_G58_I0.5561.00
56_E59_N0.5561.00
14_Q17_K0.5511.00
12_G72_A0.5501.00
40_I62_Y0.5471.00
113_S123_F0.5451.00
6_I27_A0.5441.00
15_N18_R0.5421.00
78_N81_V0.5381.00
132_V139_V0.5361.00
95_A99_D0.5231.00
59_N62_Y0.5211.00
26_L110_V0.5201.00
91_G99_D0.5201.00
114_R128_S0.5191.00
8_V19_A0.5181.00
94_A131_I0.5181.00
5_N32_A0.5171.00
131_I139_V0.5111.00
94_A134_E0.5031.00
25_D79_S0.5001.00
58_I90_E0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3s3tA 4 1 99.9 0.11 Contact Map
4wnyA 2 0.8881 99.9 0.113 Contact Map
5ahwA 4 1 99.9 0.126 Contact Map
1mjhA 2 0.958 99.9 0.128 Contact Map
2dumA 2 0.951 99.9 0.136 Contact Map
3hgmA 2 0.979 99.9 0.151 Contact Map
3loqA 1 0.951 99.9 0.154 Contact Map
3fg9A 3 0.979 99.9 0.157 Contact Map
2gm3A 2 0.8671 99.9 0.162 Contact Map
3tnjA 2 0.8601 99.9 0.166 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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