GREMLIN Database
Q97X89 - Uncharacterized protein
UniProt: Q97X89 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 129 (99)
Sequences: 2386 (1334)
Seq/√Len: 134.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
28_D31_N4.2111.00
37_Q49_R3.0321.00
47_Y81_K2.7621.00
49_R83_E2.5781.00
45_D79_S2.4941.00
91_T94_M2.2221.00
68_E72_K2.2031.00
49_R85_D2.2011.00
101_K104_I2.1131.00
95_M99_G2.0861.00
40_I46_V2.0051.00
50_I67_V2.0001.00
47_Y83_E1.9601.00
45_D78_K1.8571.00
34_L63_L1.8281.00
41_S45_D1.7781.00
14_I30_V1.7751.00
48_V71_V1.6751.00
29_I35_I1.6741.00
45_D81_K1.6501.00
18_H98_E1.4691.00
31_N99_G1.4591.00
29_I63_L1.4331.00
30_V35_I1.3671.00
12_K15_Q1.3561.00
41_S47_Y1.3361.00
62_D66_T1.3091.00
85_D88_T1.3071.00
66_T69_Q1.2971.00
36_Y94_M1.2941.00
98_E102_E1.2871.00
19_E70_V1.2571.00
72_K80_I1.2541.00
21_Y26_P1.2071.00
20_V70_V1.1971.00
51_G88_T1.1940.99
52_A59_V1.1750.99
17_L30_V1.1630.99
65_Y68_E1.1250.99
7_G10_K1.1190.99
18_H28_D1.1180.99
12_K76_Q1.1170.99
11_K15_Q1.1110.99
17_L35_I1.1070.99
64_E68_E1.1000.99
96_T99_G1.0890.99
50_I60_T1.0710.99
101_K105_R1.0620.99
71_V74_S1.0610.99
16_G70_V1.0550.99
93_L103_F0.9970.98
39_D49_R0.9940.98
31_N102_E0.9680.98
21_Y25_I0.9630.98
61_E66_T0.9580.98
18_H31_N0.9470.97
64_E84_L0.9280.97
10_K14_I0.9280.97
17_L67_V0.9250.97
39_D47_Y0.9210.97
65_Y69_Q0.9190.97
64_E82_V0.9110.97
44_G78_K0.9000.96
26_P59_V0.8830.96
16_G75_V0.8810.96
16_G20_V0.8630.96
98_E101_K0.8520.95
60_T63_L0.8440.95
26_P54_T0.8340.95
92_P100_R0.8250.94
8_E12_K0.8220.94
13_I71_V0.8180.94
97_D101_K0.8150.94
31_N98_E0.8030.93
43_E78_K0.7810.92
72_K78_K0.7750.92
99_G104_I0.7580.91
36_Y51_G0.7510.91
72_K79_S0.7420.90
9_W12_K0.7400.90
63_L92_P0.7350.90
10_K38_L0.7260.89
18_H30_V0.7250.89
35_I67_V0.7250.89
16_G77_A0.7160.89
20_V29_I0.7110.88
63_L66_T0.7080.88
7_G11_K0.7070.88
16_G74_S0.7030.88
86_L89_E0.7030.88
66_T70_V0.7030.88
58_P70_V0.6930.87
34_L50_I0.6920.87
12_K75_V0.6870.87
54_T92_P0.6850.87
38_L58_P0.6760.86
46_V77_A0.6750.86
70_V73_E0.6720.86
36_Y88_T0.6710.85
54_T59_V0.6670.85
60_T64_E0.6440.83
35_I60_T0.6300.82
21_Y28_D0.6300.82
26_P92_P0.6300.82
52_A86_L0.6280.82
34_L52_A0.6280.82
71_V80_I0.6220.81
67_V82_V0.6190.81
27_I52_A0.6190.81
99_G105_R0.6120.80
77_A80_I0.6040.79
42_D45_D0.5980.78
55_P94_M0.5980.78
16_G73_E0.5930.78
37_Q85_D0.5920.78
20_V58_P0.5910.77
37_Q47_Y0.5890.77
48_V80_I0.5870.77
21_Y34_L0.5850.77
54_T60_T0.5840.77
39_D97_D0.5830.77
95_M103_F0.5770.76
26_P55_P0.5770.76
72_K75_V0.5770.76
9_W40_I0.5740.75
25_I104_I0.5710.75
50_I86_L0.5650.74
34_L60_T0.5640.74
68_E81_K0.5630.74
54_T58_P0.5590.73
46_V71_V0.5520.73
36_Y85_D0.5460.72
33_G53_T0.5450.72
61_E64_E0.5440.71
29_I85_D0.5440.71
24_E33_G0.5380.71
55_P86_L0.5330.70
11_K47_Y0.5290.69
10_K37_Q0.5270.69
8_E11_K0.5260.69
38_L46_V0.5230.69
52_A56_A0.5220.68
51_G94_M0.5130.67
15_Q18_H0.5130.67
16_G19_E0.5110.67
9_W77_A0.5090.66
41_S72_K0.5040.66
60_T82_V0.5000.65
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3lnoA 1 0.8062 100 0.355 Contact Map
1uwdA 1 0.7907 100 0.38 Contact Map
3cq1A 2 0.7674 100 0.387 Contact Map
3ux2A 2 0.907 99.9 0.424 Contact Map
2m5oA 1 0.6589 92.5 0.877 Contact Map
1vehA 1 0.6589 89.2 0.886 Contact Map
1xhjA 1 0.6667 81.9 0.897 Contact Map
2z51A 2 0.8992 51.9 0.917 Contact Map
3w61A 2 0.5891 35.6 0.924 Contact Map
1yg0A 1 0.4884 33.2 0.926 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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