GREMLIN Database
Q97X88 - Uncharacterized protein
UniProt: Q97X88 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 115 (109)
Sequences: 1535 (1196)
Seq/√Len: 114.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
105_K109_E3.5211.00
7_V91_L3.4001.00
30_G33_K2.8541.00
54_D57_K2.5301.00
5_K15_D2.3911.00
50_W64_K2.3851.00
66_F103_A2.1971.00
62_K106_E2.1941.00
5_K89_T2.0611.00
62_K66_F1.9721.00
15_D89_T1.9421.00
92_Y99_N1.9251.00
99_N102_V1.9081.00
45_D100_N1.8381.00
3_K87_N1.8341.00
70_D107_Y1.8151.00
90_L108_L1.8031.00
66_F110_K1.7931.00
45_D49_K1.6771.00
22_D100_N1.5961.00
58_W62_K1.5871.00
17_I36_L1.5691.00
75_I78_L1.5571.00
17_I35_D1.5241.00
60_E64_K1.5001.00
42_A100_N1.4581.00
52_S57_K1.4231.00
4_L101_A1.3611.00
53_H57_K1.3471.00
58_W103_A1.3391.00
47_L50_W1.3191.00
38_L42_A1.3101.00
93_A100_N1.2830.99
92_Y101_A1.2580.99
50_W57_K1.2550.99
5_K18_R1.2330.99
7_V34_V1.2250.99
100_N103_A1.2030.99
94_S99_N1.2010.99
16_G89_T1.1970.99
78_L82_I1.1920.99
44_S68_E1.1760.99
34_V91_L1.1620.99
60_E63_K1.1620.99
80_Q83_K1.1610.99
38_L41_I1.1570.99
50_W56_S1.1530.99
51_F98_Y1.1330.99
7_V29_I1.1100.98
17_I86_E1.1060.98
15_D18_R1.1060.98
51_F99_N1.0760.98
5_K16_G1.0700.98
77_V80_Q1.0700.98
51_F92_Y1.0580.98
22_D93_A1.0530.98
75_I107_Y1.0360.98
24_L100_N1.0260.97
67_E71_A1.0200.97
38_L78_L1.0190.97
78_L81_L0.9900.97
31_K95_K0.9760.96
4_L105_K0.9720.96
22_D95_K0.9610.96
92_Y102_V0.9490.96
76_S80_Q0.9460.96
2_I88_I0.9440.96
75_I79_L0.9180.95
19_I36_L0.9040.95
76_S79_L0.8840.94
67_E70_D0.8760.94
19_I82_I0.8510.93
11_I15_D0.8410.92
72_N76_S0.8390.92
24_L48_R0.8340.92
55_T96_S0.8300.92
3_K14_D0.8270.92
74_K78_L0.8230.91
71_A74_K0.8190.91
30_G34_V0.8120.91
36_L78_L0.8070.91
57_K60_E0.8060.91
78_L83_K0.7940.90
50_W60_E0.7880.90
46_E49_K0.7850.89
76_S107_Y0.7840.89
49_K95_K0.7820.89
15_D87_N0.7810.89
53_H94_S0.7750.89
66_F106_E0.7700.88
51_F94_S0.7670.88
58_W102_V0.7630.88
72_N75_I0.7630.88
20_L26_P0.7610.88
17_I82_I0.7490.87
5_K12_E0.7480.87
5_K11_I0.7350.86
23_R45_D0.7250.85
18_R34_V0.7150.84
10_P21_V0.7130.84
24_L45_D0.7070.84
53_H98_Y0.6950.83
42_A53_H0.6940.83
63_K67_E0.6920.82
77_V81_L0.6920.82
53_H56_S0.6910.82
20_L34_V0.6830.82
19_I79_L0.6780.81
12_E15_D0.6780.81
14_D87_N0.6760.81
81_L84_K0.6750.81
74_K77_V0.6720.81
34_V88_I0.6510.78
10_P18_R0.6460.78
94_S101_A0.6460.78
58_W99_N0.6440.78
22_D94_S0.6440.78
92_Y96_S0.6420.78
19_I38_L0.6380.77
17_I38_L0.6340.77
91_L101_A0.6340.77
11_I89_T0.6290.76
24_L39_K0.6120.74
103_A107_Y0.6120.74
19_I88_I0.6050.73
102_V105_K0.6050.73
59_D73_P0.6040.73
55_T98_Y0.6030.73
21_V101_A0.5990.73
21_V104_L0.5990.73
58_W98_Y0.5970.72
106_E109_E0.5900.71
31_K48_R0.5890.71
22_D90_L0.5890.71
41_I76_S0.5880.71
62_K103_A0.5830.71
47_L60_E0.5770.70
36_L81_L0.5770.70
45_D51_F0.5750.69
50_W54_D0.5720.69
20_L104_L0.5640.68
31_K39_K0.5640.68
81_L85_G0.5590.67
29_I91_L0.5580.67
2_I83_K0.5570.67
66_F107_Y0.5510.66
51_F102_V0.5440.65
58_W107_Y0.5430.65
5_K10_P0.5310.63
46_E64_K0.5310.63
66_F70_D0.5290.63
78_L88_I0.5290.63
47_L64_K0.5260.63
52_S98_Y0.5250.63
106_E110_K0.5240.62
29_I85_G0.5240.62
31_K77_V0.5220.62
12_E60_E0.5170.61
83_K86_E0.5120.61
80_Q84_K0.5110.60
20_L25_W0.5090.60
83_K88_I0.5040.59
31_K49_K0.5020.59
79_L88_I0.5000.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gqrA 2 0.5043 21.2 0.939 Contact Map
4zu2A 3 0.7739 20.1 0.939 Contact Map
2ywvA 2 0.513 11.7 0.946 Contact Map
3nuaA 2 0.4783 11.2 0.946 Contact Map
2cxnA 2 0.7565 9.5 0.948 Contact Map
2lxeA 1 0.3217 9.5 0.948 Contact Map
3kreA 2 0.513 8.2 0.949 Contact Map
4izbA 5 0.6435 7.3 0.95 Contact Map
4wywA 1 0.7652 6 0.952 Contact Map
4q1kA 3 0.7913 5.7 0.953 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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