GREMLIN Database
Q97X87 - Uncharacterized protein
UniProt: Q97X87 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 204 (193)
Sequences: 1872 (1476)
Seq/√Len: 106.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
168_V173_L4.3651.00
162_F192_L4.2681.00
155_L159_M3.9661.00
152_I177_L3.4311.00
93_V112_I3.3631.00
159_M173_L3.2281.00
88_L93_V3.1801.00
183_T187_I3.1471.00
180_S183_T3.1401.00
157_Y197_K2.9921.00
159_M176_Q2.9661.00
148_R187_I2.8671.00
155_L173_L2.7401.00
163_D167_R2.6511.00
168_V172_E2.6031.00
169_T172_E2.5731.00
23_I104_R2.4441.00
148_R152_I2.3781.00
170_L184_L2.3741.00
148_R151_E2.2121.00
164_D185_E2.0361.00
152_I187_I1.9501.00
150_M154_K1.9431.00
11_L105_T1.9261.00
96_E111_L1.9151.00
179_I184_L1.8411.00
173_L184_L1.8071.00
22_I63_H1.7961.00
181_T185_E1.7701.00
170_L185_E1.7341.00
114_N117_A1.7111.00
166_R189_R1.7101.00
52_V55_D1.6781.00
196_V199_Y1.6521.00
168_V176_Q1.6281.00
187_I190_R1.6251.00
153_L196_V1.5951.00
142_S199_Y1.5621.00
172_E175_K1.4801.00
157_Y200_L1.4791.00
30_G48_F1.4731.00
152_I179_I1.4351.00
152_I173_L1.4171.00
11_L133_T1.4021.00
8_A118_L1.3671.00
33_D47_L1.3250.99
66_K168_V1.3200.99
98_I162_F1.2940.99
160_G167_R1.2690.99
68_L76_W1.2670.99
57_L77_V1.2630.99
173_L177_L1.2600.99
164_D186_E1.2510.99
162_F188_L1.2450.99
145_L191_A1.2380.99
159_M168_V1.2330.99
11_L135_L1.2230.99
187_I194_K1.2160.99
152_I184_L1.2090.99
186_E190_R1.2050.99
10_I122_L1.1960.99
120_E123_A1.1820.99
161_Y166_R1.1680.99
86_K90_T1.1580.98
164_D182_P1.1550.98
174_A184_L1.1480.98
182_P186_E1.1440.98
54_K58_I1.1440.98
196_V200_L1.1400.98
170_L187_I1.1360.98
193_R197_K1.1280.98
48_F56_D1.1230.98
112_I133_T1.1140.98
171_T181_T1.0980.98
183_T186_E1.0940.98
175_K178_G1.0870.98
117_A120_E1.0740.98
154_K158_K1.0720.97
10_I110_L1.0550.97
111_L162_F1.0510.97
153_L162_F1.0490.97
183_T191_A1.0470.97
177_L184_L1.0360.97
8_A11_L1.0330.97
157_Y162_F1.0270.97
32_V46_V1.0220.97
107_L135_L1.0090.96
60_L190_R1.0080.96
93_V97_K0.9950.96
164_D189_R0.9940.96
60_L65_T0.9920.96
64_S67_V0.9810.96
170_L181_T0.9690.95
16_P179_I0.9650.95
74_K147_D0.9530.95
53_Q57_L0.9510.95
67_V77_V0.9490.95
53_Q56_D0.9330.94
52_V63_H0.9320.94
195_V199_Y0.9180.94
152_I191_A0.9180.94
95_V110_L0.9100.94
195_V198_F0.9020.93
162_F170_L0.9010.93
144_E198_F0.9010.93
32_V35_V0.8980.93
55_D58_I0.8940.93
125_L130_I0.8770.92
188_L192_L0.8720.92
148_R186_E0.8640.92
32_V111_L0.8630.92
92_N124_S0.8610.92
122_L132_F0.8610.92
170_L183_T0.8530.91
67_V74_K0.8500.91
161_Y188_L0.8450.91
164_D187_I0.8360.90
17_C23_I0.8330.90
183_T188_L0.8330.90
89_Y173_L0.8260.90
23_I105_T0.8210.90
83_A86_K0.8200.90
112_I162_F0.8170.89
180_S189_R0.8120.89
53_Q75_I0.8100.89
155_L176_Q0.8090.89
10_I108_Y0.7990.88
64_S129_D0.7970.88
56_D140_I0.7950.88
27_G129_D0.7950.88
149_Q194_K0.7940.88
181_T190_R0.7910.88
179_I182_P0.7880.88
161_Y170_L0.7870.88
151_E155_L0.7860.87
123_A127_S0.7800.87
163_D193_R0.7790.87
81_G88_L0.7760.87
51_E62_S0.7720.87
93_V96_E0.7700.86
8_A12_I0.7670.86
13_E20_M0.7670.86
137_T161_Y0.7660.86
17_C20_M0.7640.86
18_E22_I0.7630.86
162_F191_A0.7600.86
20_M23_I0.7570.85
122_L183_T0.7550.85
134_V137_T0.7500.85
56_D59_K0.7490.85
23_I101_V0.7460.85
81_G162_F0.7440.84
98_I112_I0.7430.84
155_L177_L0.7410.84
164_D171_T0.7410.84
55_D77_V0.7390.84
73_N80_Y0.7360.84
16_P46_V0.7340.84
43_D105_T0.7270.83
183_T190_R0.7270.83
115_T137_T0.7230.83
115_T180_S0.7220.83
32_V63_H0.7200.83
101_V106_L0.7100.82
47_L76_W0.7040.81
82_C162_F0.7010.81
120_E167_R0.7000.81
49_E74_K0.7000.81
26_T51_E0.6980.81
43_D135_L0.6950.80
121_F181_T0.6950.80
136_S173_L0.6900.80
82_C169_T0.6870.79
9_T107_L0.6860.79
171_T189_R0.6830.79
191_A196_V0.6820.79
164_D193_R0.6820.79
190_R195_V0.6810.79
143_N199_Y0.6800.79
153_L200_L0.6800.79
96_E109_T0.6790.79
44_H95_V0.6770.78
37_L108_Y0.6730.78
51_E176_Q0.6710.78
87_I90_T0.6680.78
119_K122_L0.6660.77
88_L91_S0.6640.77
21_K135_L0.6620.77
53_Q77_V0.6590.77
32_V115_T0.6590.77
190_R193_R0.6590.77
151_E184_L0.6560.76
10_I186_E0.6530.76
65_T92_N0.6520.76
85_C184_L0.6510.76
49_E55_D0.6500.76
23_I103_E0.6480.75
94_V111_L0.6470.75
17_C84_V0.6450.75
30_G38_G0.6440.75
78_R132_F0.6430.75
71_N74_K0.6420.75
151_E154_K0.6420.75
79_T142_S0.6400.75
95_V120_E0.6370.74
67_V75_I0.6360.74
28_L50_K0.6310.73
151_E179_I0.6270.73
69_R74_K0.6270.73
154_K200_L0.6260.73
17_C106_L0.6240.73
24_S31_V0.6230.73
88_L110_L0.6220.72
168_V184_L0.6220.72
21_K105_T0.6200.72
121_F186_E0.6140.71
71_N76_W0.6040.70
65_T77_V0.6010.70
7_E138_S0.5980.69
72_D135_L0.5950.69
30_G146_T0.5930.69
160_G163_D0.5910.69
8_A115_T0.5900.68
97_K162_F0.5880.68
25_S200_L0.5860.68
28_L150_M0.5860.68
64_S74_K0.5840.68
73_N78_R0.5840.68
50_K116_M0.5830.68
155_L168_V0.5830.68
113_P176_Q0.5800.67
18_E34_N0.5800.67
172_E177_L0.5790.67
130_I138_S0.5780.67
33_D76_W0.5780.67
16_P80_Y0.5780.67
30_G190_R0.5770.67
110_L114_N0.5760.67
166_R195_V0.5720.66
24_S104_R0.5680.66
50_K56_D0.5660.65
69_R177_L0.5630.65
102_R105_T0.5620.65
19_V106_L0.5570.64
14_E17_C0.5540.64
160_G185_E0.5540.64
68_L72_D0.5510.63
170_L191_A0.5500.63
137_T171_T0.5500.63
15_H20_M0.5490.63
82_C88_L0.5490.63
8_A110_L0.5490.63
14_E18_E0.5480.63
31_V34_N0.5470.63
21_K24_S0.5470.63
150_M198_F0.5470.63
65_T68_L0.5460.62
22_I26_T0.5450.62
124_S128_Q0.5440.62
171_T175_K0.5420.62
35_V126_I0.5420.62
15_H18_E0.5400.62
85_C146_T0.5400.62
72_D109_T0.5370.61
41_T195_V0.5370.61
61_K133_T0.5360.61
97_K177_L0.5340.61
110_L121_F0.5320.61
161_Y195_V0.5320.61
85_C153_L0.5300.60
54_K57_L0.5280.60
10_I134_V0.5270.60
165_D189_R0.5250.60
37_L42_T0.5200.59
107_L174_A0.5190.59
51_E114_N0.5190.59
62_S73_N0.5190.59
32_V37_L0.5180.58
74_K195_V0.5180.58
53_Q74_K0.5140.58
30_G46_V0.5140.58
26_T59_K0.5130.58
91_S124_S0.5110.57
81_G120_E0.5110.57
69_R72_D0.5050.57
12_I80_Y0.5040.56
177_L185_E0.5040.56
161_Y186_E0.5020.56
91_S117_A0.5000.56
32_V36_K0.5000.56
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1s7oA 3 0.3431 97.6 0.84 Contact Map
1ku3A 1 0.299 97.5 0.842 Contact Map
4wszA 2 0.2794 97.5 0.843 Contact Map
1x3uA 1 0.3333 97.3 0.848 Contact Map
1je8A 2 0.2843 97.2 0.849 Contact Map
2o8xA 7 0.299 97.2 0.85 Contact Map
1fseA 2 0.2892 97.2 0.85 Contact Map
1xsvA 2 0.3431 97.2 0.85 Contact Map
3c57A 2 0.25 97.1 0.853 Contact Map
4g6dA 1 0.3039 97.1 0.853 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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