GREMLIN Database
Q97X31 - Uncharacterized protein
UniProt: Q97X31 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 131 (121)
Sequences: 462 (415)
Seq/√Len: 37.7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_S99_F4.3871.00
32_T36_S3.7781.00
82_E104_K3.5651.00
8_S22_V2.8941.00
47_K52_E2.8041.00
31_M106_N2.7811.00
92_I97_S2.5511.00
101_A105_S2.3641.00
10_V43_S2.3591.00
9_L36_S2.3471.00
14_S47_K2.2590.99
9_L12_F2.1810.99
112_T118_Y2.1660.99
37_I73_I2.1290.99
48_I88_N2.1140.99
6_S43_S2.0120.99
41_A94_V1.9480.98
11_K16_E1.9330.98
54_K57_V1.8960.98
12_F22_V1.8270.98
11_K113_S1.7360.97
83_A98_L1.6450.95
32_T71_L1.6240.95
12_F26_I1.5690.94
79_Y83_A1.5490.94
58_V84_F1.5330.93
38_K98_L1.5190.93
99_F102_L1.5040.93
16_E19_W1.4600.91
86_I97_S1.4240.90
32_T73_I1.4080.90
6_S9_L1.3900.89
34_D75_S1.3630.88
48_I58_V1.3170.86
40_V43_S1.2860.85
40_V65_L1.2800.85
31_M74_V1.2770.85
82_E85_K1.2560.84
6_S10_V1.2550.84
33_L69_E1.2390.83
16_E52_E1.1870.80
82_E101_A1.1690.79
62_L87_A1.1550.78
71_L97_S1.1430.77
93_T97_S1.1270.76
115_K119_E1.1190.76
13_F61_I1.1120.75
21_K24_E1.0650.72
84_F91_K1.0550.71
45_W49_L1.0540.71
100_I121_A1.0200.69
4_I30_V1.0150.68
69_E92_I1.0130.68
59_I62_L1.0120.68
74_V101_A1.0040.68
36_S71_L1.0020.67
17_K52_E0.9900.67
2_R12_F0.9880.66
101_A104_K0.9820.66
74_V102_L0.9740.65
90_N93_T0.9610.64
87_A110_L0.9590.64
8_S12_F0.9570.64
66_L84_F0.9370.62
46_K52_E0.9320.62
21_K51_G0.9210.61
44_L49_L0.9180.61
22_V111_V0.9070.60
58_V103_A0.8930.58
76_Q85_K0.8930.58
92_I100_I0.8900.58
42_N45_W0.8890.58
4_I9_L0.8800.57
63_S81_I0.8770.57
42_N95_Y0.8690.56
71_L92_I0.8690.56
16_E47_K0.8550.55
32_T65_L0.8420.54
8_S31_M0.8340.53
93_T116_K0.8310.53
22_V106_N0.8240.52
9_L99_F0.8130.51
35_L100_I0.8110.51
3_V102_L0.8030.50
25_I62_L0.8020.50
86_I101_A0.8010.50
34_D76_Q0.7990.50
92_I98_L0.7890.49
86_I104_K0.7820.49
24_E107_N0.7790.48
32_T99_F0.7790.48
17_K50_L0.7780.48
41_A77_D0.7750.48
61_I75_S0.7700.48
116_K119_E0.7630.47
53_M111_V0.7560.46
30_V111_V0.7450.45
76_Q84_F0.7440.45
10_V40_V0.7430.45
45_W84_F0.7410.45
24_E56_D0.7300.44
54_K63_S0.7260.44
46_K50_L0.7240.44
33_L99_F0.7170.43
64_D94_V0.7060.42
90_N97_S0.7030.42
40_V90_N0.7010.41
45_W93_T0.6970.41
35_L66_L0.6940.41
14_S53_M0.6930.41
29_G54_K0.6840.40
9_L32_T0.6820.40
39_E95_Y0.6780.40
60_K82_E0.6750.39
13_F116_K0.6660.39
16_E97_S0.6630.38
7_S89_R0.6610.38
71_L120_V0.6560.38
26_I56_D0.6520.37
113_S118_Y0.6500.37
13_F26_I0.6380.36
33_L49_L0.6340.36
33_L36_S0.6280.35
28_E64_D0.6280.35
92_I120_V0.6250.35
110_L121_A0.6210.35
22_V28_E0.6140.34
10_V14_S0.6130.34
20_E24_E0.6080.34
35_L51_G0.6060.34
6_S68_R0.6040.33
36_S99_F0.6020.33
19_W22_V0.6000.33
68_R84_F0.5980.33
44_L70_A0.5920.32
39_E42_N0.5910.32
119_E122_I0.5910.32
117_Q121_A0.5900.32
56_D74_V0.5870.32
72_L116_K0.5860.32
32_T69_E0.5800.32
29_G72_L0.5740.31
56_D78_E0.5720.31
55_E89_R0.5720.31
7_S119_E0.5710.31
20_E59_I0.5680.31
37_I41_A0.5640.30
20_E107_N0.5640.30
13_F21_K0.5610.30
91_K115_K0.5570.30
25_I51_G0.5540.30
8_S113_S0.5520.29
83_A92_I0.5470.29
14_S117_Q0.5440.29
33_L117_Q0.5430.29
79_Y101_A0.5370.28
16_E50_L0.5360.28
9_L69_E0.5360.28
24_E28_E0.5340.28
29_G41_A0.5320.28
4_I72_L0.5310.28
74_V78_E0.5300.28
36_S69_E0.5300.28
56_D61_I0.5290.28
11_K22_V0.5280.28
34_D119_E0.5280.28
33_L70_A0.5270.28
4_I8_S0.5240.27
38_K41_A0.5220.27
4_I100_I0.5220.27
13_F118_Y0.5210.27
38_K79_Y0.5180.27
44_L58_V0.5160.27
24_E55_E0.5160.27
4_I26_I0.5080.26
86_I100_I0.5080.26
43_S51_G0.5040.26
34_D53_M0.5010.26
8_S21_K0.5010.26
27_S71_L0.5010.26
38_K109_E0.5000.26
110_L113_S0.5000.26
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2fe1A 2 0.9542 99.7 0.529 Contact Map
1v8pA 4 0.9237 99.6 0.565 Contact Map
1w8iA 2 0.916 99.2 0.659 Contact Map
4chgA 2 0.9237 99 0.686 Contact Map
2h1cA 2 0.9466 99 0.689 Contact Map
3tndA 3 0.9084 98.9 0.702 Contact Map
3ix7A 2 0.8855 98.9 0.708 Contact Map
3zvkA 3 0.9084 98.8 0.709 Contact Map
3h87A 3 0.9084 98.6 0.732 Contact Map
1o4wA 2 0.8397 98.5 0.739 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0061 seconds.