THIC2 - SULSO - GREMLIN Contacts

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THIC2 - Phosphomethylpyrimidine synthase 2

UniProt:	Q97X14	Sequences: MGIIDEAKRGQITDEMRAISKLEGIPVEKVRNRISEGKIMLIRNAKYPSRKLVPIGKGLTTKVNVNIGTSSEVVDLDMELQKVKVANKWGDTLMDLSTGGDLDAIRRDIIKASDLPVGTVPVYQIFIESFKKKSGGAYFTEDELLNTVEKHLKDGVAFMTIHAGITKDLAIRALKSDRIIPIVSRGGDMIAGWMIHNNSENPYRKNWDYVLEMFKEYDAVISLGDALRPGATGDAHDEFQIGELLETARLVKSALQKGVQVMVEGPGHVPLNEIAWDVKLMKKLTGGVPYYVLGPLPIDVGAPYDHIASAIGAAISSASGVDLLCYLTPAEHLGLPTVKQVEEGAIAYRIAAHAGDVVKLGRKARKWDDEVSYYRGKLDWENMISKLIDPQRAYQVYTQFGTPKVKACTMCGGYCPMMWAMDQVRKIGSSSSL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	433 (418)
Sequences:	1095 (407)
Seq/√Len:	19.9

ECOLI - THIC
BACSU - THIC
HALSA - THIC
SULSO - THIC2 THIC1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
381_E	394_Y	3.718	1.00
103_D	150_K	3.717	1.00
61_T	359_K	3.370	1.00
382_N	385_S	3.252	1.00
251_V	255_L	3.241	1.00
54_P	59_L	3.238	1.00
33_R	39_I	3.102	0.99
251_V	263_V	3.066	0.99
145_L	209_Y	2.982	0.99
275_A	279_K	2.956	0.99
180_I	417_M	2.930	0.99
343_E	392_R	2.927	0.99
83_V	93_L	2.882	0.99
297_P	354_A	2.868	0.99
34_I	41_L	2.825	0.99
19_I	54_P	2.821	0.99
214_F	221_I	2.729	0.98
180_I	231_A	2.696	0.98
14_D	17_R	2.619	0.98
25_I	30_V	2.576	0.98
145_L	210_V	2.555	0.98
28_E	31_R	2.543	0.98
152_L	219_A	2.519	0.97
148_V	203_Y	2.502	0.97
212_E	257_K	2.427	0.97
12_I	31_R	2.422	0.97
149_E	153_K	2.381	0.96
103_D	124_Q	2.350	0.96
107_R	154_D	2.313	0.96
313_A	324_L	2.293	0.95
5_D	215_K	2.290	0.95
370_E	382_N	2.238	0.95
75_D	78_M	2.197	0.94
19_I	41_L	2.195	0.94
30_V	39_I	2.185	0.94
300_V	367_W	2.178	0.94
182_I	191_A	2.173	0.94
349_R	367_W	2.154	0.94
13_T	16_M	2.126	0.93
38_K	57_K	2.122	0.93
353_H	368_D	2.101	0.93
271_L	314_A	2.099	0.93
65_V	345_A	2.086	0.92
29_K	33_R	2.059	0.92
17_R	21_K	2.040	0.92
278_V	319_S	2.036	0.91
22_L	51_K	2.027	0.91
27_V	31_R	2.026	0.91
149_E	216_E	2.011	0.91
119_T	156_V	1.995	0.91
252_K	286_G	1.988	0.90
302_A	308_A	1.939	0.89
208_D	253_S	1.937	0.89
215_K	257_K	1.933	0.89
101_D	104_A	1.919	0.89
271_L	315_I	1.917	0.89
236_H	277_D	1.907	0.89
81_Q	338_V	1.886	0.88
38_K	287_G	1.876	0.88
148_V	210_V	1.852	0.87
179_I	369_D	1.828	0.86
3_I	16_M	1.827	0.86
81_Q	84_K	1.817	0.86
124_Q	128_E	1.798	0.85
161_I	221_I	1.795	0.85
365_R	369_D	1.788	0.85
30_V	33_R	1.786	0.85
179_I	233_G	1.756	0.84
255_L	286_G	1.745	0.84
152_L	159_M	1.720	0.83
39_I	59_L	1.720	0.83
215_K	258_G	1.712	0.82
87_N	114_D	1.685	0.81
33_R	38_K	1.675	0.81
17_R	27_V	1.649	0.80
5_D	258_G	1.638	0.79
272_N	360_L	1.635	0.79
199_S	205_K	1.596	0.77
211_L	221_I	1.592	0.77
273_E	283_K	1.588	0.77
309_S	327_L	1.587	0.77
373_Y	377_K	1.575	0.77
167_K	198_N	1.560	0.76
161_I	210_V	1.555	0.76
4_I	40_M	1.553	0.75
263_V	281_M	1.550	0.75
326_Y	341_V	1.549	0.75
395_Q	399_Q	1.538	0.75
40_M	220_V	1.531	0.74
374_Y	382_N	1.530	0.74
61_T	361_G	1.514	0.74
213_M	219_A	1.502	0.73
3_I	13_T	1.497	0.73
43_R	50_R	1.488	0.72
12_I	27_V	1.478	0.72
281_M	290_Y	1.477	0.72
32_N	36_E	1.467	0.71
370_E	386_K	1.463	0.71
382_N	386_K	1.461	0.71
223_L	247_T	1.458	0.71
277_D	290_Y	1.455	0.71
141_E	206_N	1.452	0.70
236_H	290_Y	1.451	0.70
204_R	249_R	1.451	0.70
342_E	346_I	1.448	0.70
379_D	382_N	1.448	0.70
281_M	285_T	1.438	0.70
67_I	83_V	1.434	0.69
179_I	231_A	1.417	0.68
9_R	258_G	1.412	0.68
66_N	160_T	1.410	0.68
244_L	290_Y	1.402	0.68
41_L	54_P	1.399	0.67
65_V	86_A	1.386	0.67
84_K	112_A	1.383	0.66
83_V	113_S	1.363	0.65
92_T	116_P	1.357	0.65
313_A	348_Y	1.344	0.64
206_N	209_Y	1.344	0.64
30_V	34_I	1.339	0.64
4_I	255_L	1.334	0.64
42_I	55_I	1.324	0.63
339_K	343_E	1.304	0.62
232_T	357_V	1.301	0.62
65_V	93_L	1.299	0.61
342_E	392_R	1.296	0.61
110_I	151_H	1.289	0.61
88_K	391_Q	1.286	0.61
168_D	200_E	1.283	0.60
171_I	175_K	1.281	0.60
246_E	249_R	1.281	0.60
141_E	205_K	1.271	0.60
372_S	417_M	1.269	0.60
158_F	323_L	1.266	0.59
255_L	263_V	1.259	0.59
231_A	372_S	1.258	0.59
58_G	322_D	1.247	0.58
16_M	30_V	1.243	0.58
149_E	209_Y	1.239	0.58
317_S	355_G	1.231	0.57
6_E	11_Q	1.229	0.57
63_V	345_A	1.227	0.57
86_A	345_A	1.227	0.57
151_H	159_M	1.226	0.57
400_F	409_T	1.225	0.57
211_L	259_V	1.225	0.57
207_W	223_L	1.225	0.57
298_I	301_G	1.224	0.57
80_L	83_V	1.222	0.57
275_A	319_S	1.222	0.57
236_H	241_I	1.221	0.57
272_N	365_R	1.217	0.56
241_I	280_L	1.211	0.56
369_D	373_Y	1.208	0.56
169_L	246_E	1.201	0.55
87_N	113_S	1.197	0.55
40_M	262_M	1.193	0.55
57_K	287_G	1.192	0.55
168_D	171_I	1.186	0.54
64_N	70_S	1.181	0.54
282_K	322_D	1.176	0.54
19_I	34_I	1.172	0.53
363_K	366_K	1.153	0.52
7_A	13_T	1.150	0.52
102_L	105_I	1.150	0.52
318_A	359_K	1.145	0.52
221_I	263_V	1.139	0.51
29_K	39_I	1.133	0.51
100_G	105_I	1.130	0.51
167_K	194_M	1.124	0.50
255_L	288_V	1.118	0.50
235_A	273_E	1.117	0.50
307_I	347_A	1.114	0.50
144_L	148_V	1.109	0.49
211_L	257_K	1.109	0.49
120_V	293_L	1.108	0.49
324_L	348_Y	1.107	0.49
103_D	154_D	1.105	0.49
113_S	117_V	1.101	0.49
418_M	422_D	1.096	0.49
4_I	251_V	1.086	0.48
172_R	242_G	1.083	0.48
142_D	145_L	1.082	0.48
225_D	229_P	1.079	0.47
245_L	284_L	1.079	0.47
46_K	217_Y	1.077	0.47
85_V	89_W	1.077	0.47
292_V	316_S	1.068	0.47
392_R	395_Q	1.062	0.46
18_A	51_K	1.061	0.46
180_I	372_S	1.056	0.46
278_V	321_V	1.052	0.46
106_R	154_D	1.051	0.46
148_V	159_M	1.051	0.46
141_E	145_L	1.050	0.46
300_V	353_H	1.046	0.45
16_M	31_R	1.043	0.45
109_I	117_V	1.038	0.45
64_N	264_E	1.032	0.44
64_N	120_V	1.032	0.44
253_S	257_K	1.029	0.44
60_T	349_R	1.028	0.44
188_D	416_P	1.026	0.44
346_I	349_R	1.026	0.44
381_E	385_S	1.025	0.44
209_Y	216_E	1.023	0.44
25_I	29_K	1.018	0.44
370_E	373_Y	1.018	0.44
55_I	116_P	1.016	0.43
280_L	290_Y	1.016	0.43
151_H	154_D	1.012	0.43
309_S	348_Y	1.002	0.43
300_V	368_D	1.000	0.42
406_K	421_M	1.000	0.42
89_W	345_A	0.996	0.42
315_I	319_S	0.995	0.42
3_I	218_D	0.992	0.42
134_S	138_Y	0.992	0.42
53_V	91_D	0.988	0.42
26_P	29_K	0.987	0.42
238_E	252_K	0.985	0.41
264_E	293_L	0.978	0.41
67_I	93_L	0.976	0.41
120_V	264_E	0.975	0.41
61_T	356_D	0.974	0.41
224_G	264_E	0.974	0.41
172_R	249_R	0.971	0.41
245_L	280_L	0.967	0.40
251_V	286_G	0.964	0.40
34_I	54_P	0.962	0.40
47_Y	52_L	0.954	0.40
64_N	293_L	0.953	0.39
211_L	214_F	0.944	0.39
285_T	290_Y	0.944	0.39
168_D	242_G	0.943	0.39
243_E	295_P	0.942	0.39
406_K	418_M	0.942	0.39
164_G	247_T	0.941	0.39
270_P	273_E	0.939	0.39
387_L	390_P	0.937	0.38
16_M	41_L	0.936	0.38
334_G	400_F	0.936	0.38
91_D	349_R	0.935	0.38
274_I	315_I	0.933	0.38
164_G	223_L	0.931	0.38
87_N	115_L	0.924	0.38
146_N	149_E	0.924	0.38
142_D	209_Y	0.922	0.38
391_Q	395_Q	0.916	0.37
30_V	59_L	0.915	0.37
34_I	40_M	0.913	0.37
89_W	342_E	0.913	0.37
117_V	272_N	0.911	0.37
40_M	255_L	0.909	0.37
70_S	224_G	0.906	0.37
296_L	309_S	0.906	0.37
392_R	396_V	0.905	0.37
63_V	117_V	0.904	0.36
61_T	318_A	0.904	0.36
323_L	348_Y	0.902	0.36
108_D	111_K	0.902	0.36
224_G	293_L	0.901	0.36
247_T	263_V	0.900	0.36
254_A	261_V	0.895	0.36
58_G	282_K	0.893	0.36
84_K	88_K	0.890	0.36
202_P	316_S	0.885	0.35
380_W	410_M	0.885	0.35
146_N	150_K	0.884	0.35
53_V	116_P	0.881	0.35
384_I	393_A	0.878	0.35
179_I	373_Y	0.877	0.35
185_R	293_L	0.877	0.35
271_L	274_I	0.875	0.35
251_V	354_A	0.873	0.35
337_T	399_Q	0.860	0.34
18_A	21_K	0.856	0.34
139_F	197_N	0.855	0.34
161_I	203_Y	0.855	0.34
7_A	35_S	0.854	0.34
160_T	291_Y	0.851	0.33
16_M	35_S	0.850	0.33
64_N	224_G	0.849	0.33
244_L	281_M	0.848	0.33
163_A	273_E	0.848	0.33
165_I	226_A	0.847	0.33
70_S	264_E	0.847	0.33
176_S	238_E	0.844	0.33
65_V	83_V	0.841	0.33
148_V	161_I	0.841	0.33
39_I	58_G	0.839	0.33
144_L	203_Y	0.838	0.33
409_T	424_V	0.836	0.32
120_V	291_Y	0.831	0.32
191_A	420_A	0.830	0.32
152_L	213_M	0.828	0.32
70_S	293_L	0.822	0.32
7_A	16_M	0.821	0.32
301_G	350_I	0.821	0.32
109_I	355_G	0.820	0.32
236_H	273_E	0.818	0.31
161_I	166_T	0.816	0.31
160_T	293_L	0.816	0.31
33_R	58_G	0.815	0.31
4_I	258_G	0.814	0.31
298_I	368_D	0.811	0.31
179_I	372_S	0.807	0.31
397_Y	407_A	0.805	0.31
397_Y	406_K	0.801	0.31
317_S	361_G	0.799	0.30
176_S	286_G	0.799	0.30
163_A	221_I	0.799	0.30
144_L	147_T	0.797	0.30
160_T	235_A	0.796	0.30
244_L	277_D	0.794	0.30
244_L	280_L	0.791	0.30
142_D	198_N	0.790	0.30
181_P	189_M	0.789	0.30
70_S	120_V	0.789	0.30
80_L	113_S	0.786	0.30
36_E	287_G	0.784	0.30
120_V	224_G	0.782	0.30
159_M	214_F	0.780	0.29
276_W	279_K	0.779	0.29
95_D	229_P	0.777	0.29
48_P	111_K	0.775	0.29
12_I	28_E	0.775	0.29
346_I	350_I	0.772	0.29
308_A	327_L	0.770	0.29
39_I	54_P	0.766	0.29
141_E	209_Y	0.765	0.29
143_E	151_H	0.762	0.28
343_E	347_A	0.761	0.28
66_N	224_G	0.760	0.28
334_G	396_V	0.754	0.28
277_D	291_Y	0.753	0.28
76_L	104_A	0.752	0.28
188_D	419_W	0.750	0.28
95_D	225_D	0.749	0.28
133_K	138_Y	0.748	0.28
397_Y	400_F	0.743	0.27
171_I	324_L	0.741	0.27
219_A	385_S	0.741	0.27
67_I	136_G	0.740	0.27
231_A	355_G	0.735	0.27
66_N	182_I	0.734	0.27
208_D	257_K	0.733	0.27
36_E	57_K	0.731	0.27
378_L	407_A	0.731	0.27
92_T	323_L	0.729	0.27
90_G	341_V	0.728	0.27
204_R	207_W	0.728	0.27
91_D	188_D	0.727	0.27
272_N	279_K	0.724	0.26
69_T	98_T	0.722	0.26
388_I	391_Q	0.721	0.26
185_R	264_E	0.720	0.26
22_L	53_V	0.717	0.26
165_I	209_Y	0.715	0.26
135_G	138_Y	0.714	0.26
145_L	149_E	0.713	0.26
240_Q	292_V	0.712	0.26
107_R	338_V	0.711	0.26
367_W	388_I	0.711	0.26
163_A	250_L	0.704	0.25
139_F	143_E	0.704	0.25
85_V	338_V	0.700	0.25
64_N	69_T	0.700	0.25
160_T	182_I	0.696	0.25
160_T	225_D	0.693	0.25
80_L	84_K	0.687	0.25
334_G	383_M	0.684	0.25
85_V	88_K	0.683	0.24
120_V	185_R	0.682	0.24
8_K	258_G	0.681	0.24
93_L	115_L	0.681	0.24
207_W	221_I	0.680	0.24
174_L	195_I	0.679	0.24
338_V	345_A	0.676	0.24
232_T	372_S	0.675	0.24
209_Y	212_E	0.673	0.24
119_T	227_L	0.672	0.24
180_I	190_I	0.672	0.24
214_F	259_V	0.672	0.24
161_I	214_F	0.672	0.24
315_I	318_A	0.670	0.24
53_V	92_T	0.669	0.24
151_H	181_P	0.665	0.24
154_D	217_Y	0.661	0.23
55_I	394_Y	0.660	0.23
159_M	219_A	0.658	0.23
159_M	166_T	0.655	0.23
12_I	16_M	0.655	0.23
241_I	244_L	0.655	0.23
31_R	35_S	0.654	0.23
276_W	283_K	0.654	0.23
79_E	82_K	0.651	0.23
32_N	216_E	0.650	0.23
114_D	157_A	0.649	0.23
311_I	314_A	0.649	0.23
165_I	169_L	0.648	0.23
313_A	371_V	0.647	0.23
94_M	293_L	0.646	0.23
248_A	285_T	0.646	0.23
7_A	10_G	0.645	0.23
371_V	387_L	0.640	0.22
242_G	371_V	0.640	0.22
388_I	393_A	0.640	0.22
63_V	258_G	0.640	0.22
160_T	185_R	0.638	0.22
273_E	276_W	0.637	0.22
248_A	288_V	0.636	0.22
5_D	9_R	0.634	0.22
191_A	424_V	0.633	0.22
396_V	400_F	0.633	0.22
88_K	349_R	0.633	0.22
378_L	417_M	0.633	0.22
95_D	119_T	0.631	0.22
240_Q	244_L	0.630	0.22
355_G	360_L	0.628	0.22
165_I	227_L	0.628	0.22
315_I	346_I	0.627	0.22
164_G	226_A	0.627	0.22
44_N	157_A	0.627	0.22
212_E	215_K	0.627	0.22
13_T	41_L	0.626	0.22
2_G	5_D	0.625	0.22
157_A	220_V	0.624	0.22
59_L	317_S	0.623	0.22
42_I	220_V	0.623	0.22
337_T	401_G	0.622	0.22
119_T	147_T	0.621	0.22
190_I	210_V	0.621	0.22
271_L	319_S	0.621	0.22
214_F	219_A	0.620	0.22
144_L	202_P	0.618	0.21
3_I	7_A	0.618	0.21
207_W	247_T	0.615	0.21
163_A	292_V	0.614	0.21
309_S	406_K	0.614	0.21
358_V	386_K	0.613	0.21
15_E	18_A	0.612	0.21
172_R	245_L	0.612	0.21
90_G	409_T	0.611	0.21
405_V	409_T	0.610	0.21
137_A	192_G	0.610	0.21
26_P	32_N	0.610	0.21
101_D	128_E	0.609	0.21
271_L	360_L	0.609	0.21
366_K	370_E	0.608	0.21
408_C	411_C	0.608	0.21
137_A	196_H	0.607	0.21
99_G	102_L	0.607	0.21
172_R	246_E	0.606	0.21
264_E	291_Y	0.605	0.21
247_T	288_V	0.604	0.21
42_I	53_V	0.604	0.21
94_M	118_G	0.604	0.21
252_K	302_A	0.602	0.21
145_L	226_A	0.602	0.21
339_K	342_E	0.602	0.21
394_Y	398_T	0.601	0.21
145_L	206_N	0.601	0.21
47_Y	50_R	0.599	0.21
231_A	383_M	0.596	0.21
238_E	245_L	0.596	0.21
99_G	189_M	0.594	0.20
87_N	112_A	0.594	0.20
95_D	156_V	0.593	0.20
33_R	57_K	0.593	0.20
110_I	117_V	0.591	0.20
66_N	70_S	0.590	0.20
107_R	111_K	0.589	0.20
408_C	415_C	0.589	0.20
411_C	415_C	0.589	0.20
113_S	188_D	0.588	0.20
124_Q	147_T	0.588	0.20
235_A	291_Y	0.587	0.20
397_Y	409_T	0.587	0.20
24_G	27_V	0.586	0.20
226_A	288_V	0.585	0.20
11_Q	359_K	0.584	0.20
189_M	372_S	0.584	0.20
207_W	278_V	0.583	0.20
238_E	249_R	0.583	0.20
34_I	263_V	0.583	0.20
17_R	300_V	0.583	0.20
229_P	316_S	0.582	0.20
367_W	372_S	0.582	0.20
269_V	280_L	0.582	0.20
64_N	185_R	0.580	0.20
236_H	280_L	0.580	0.20
145_L	262_M	0.580	0.20
120_V	160_T	0.579	0.20
182_I	224_G	0.579	0.20
98_T	224_G	0.579	0.20
166_T	239_F	0.578	0.20
55_I	122_V	0.578	0.20
251_V	355_G	0.578	0.20
374_Y	386_K	0.577	0.20
125_I	318_A	0.576	0.20
148_V	163_A	0.576	0.20
314_A	318_A	0.576	0.20
71_S	337_T	0.575	0.20
153_K	171_I	0.575	0.20
150_K	154_D	0.573	0.20
77_D	81_Q	0.572	0.20
185_R	291_Y	0.572	0.20
207_W	254_A	0.572	0.20
205_K	209_Y	0.572	0.20
98_T	226_A	0.571	0.20
95_D	292_V	0.570	0.19
377_K	421_M	0.567	0.19
77_D	111_K	0.567	0.19
77_D	108_D	0.567	0.19
403_P	407_A	0.566	0.19
300_V	349_R	0.566	0.19
193_W	197_N	0.566	0.19
164_G	210_V	0.566	0.19
69_T	335_L	0.565	0.19
9_R	256_Q	0.565	0.19
118_G	293_L	0.565	0.19
251_V	281_M	0.564	0.19
77_D	84_K	0.564	0.19
6_E	9_R	0.564	0.19
137_A	181_P	0.563	0.19
124_Q	383_M	0.561	0.19
98_T	419_W	0.560	0.19
247_T	295_P	0.560	0.19
108_D	112_A	0.560	0.19
141_E	199_S	0.560	0.19
278_V	292_V	0.560	0.19
313_A	323_L	0.559	0.19
25_I	366_K	0.558	0.19
202_P	292_V	0.558	0.19
64_N	291_Y	0.558	0.19
5_D	257_K	0.554	0.19
173_A	238_E	0.554	0.19
159_M	210_V	0.554	0.19
164_G	277_D	0.552	0.19
174_L	238_E	0.551	0.19
126_F	189_M	0.551	0.19
166_T	407_A	0.550	0.19
160_T	164_G	0.549	0.19
124_Q	132_K	0.549	0.19
4_I	34_I	0.549	0.19
69_T	102_L	0.547	0.19
346_I	392_R	0.547	0.19
92_T	158_F	0.546	0.19
24_G	362_R	0.546	0.19
302_A	333_L	0.544	0.18
44_N	47_Y	0.544	0.18
378_L	420_A	0.543	0.18
137_A	189_M	0.542	0.18
195_I	337_T	0.542	0.18
55_I	110_I	0.542	0.18
240_Q	326_Y	0.541	0.18
181_P	191_A	0.540	0.18
156_V	232_T	0.540	0.18
367_W	386_K	0.539	0.18
202_P	379_D	0.539	0.18
85_V	345_A	0.539	0.18
251_V	261_V	0.538	0.18
182_I	189_M	0.537	0.18
124_Q	181_P	0.536	0.18
273_E	277_D	0.536	0.18
198_N	349_R	0.535	0.18
147_T	343_E	0.535	0.18
174_L	400_F	0.534	0.18
102_L	124_Q	0.534	0.18
4_I	8_K	0.533	0.18
64_N	335_L	0.532	0.18
302_A	371_V	0.532	0.18
217_Y	357_V	0.531	0.18
158_F	348_Y	0.531	0.18
49_S	63_V	0.530	0.18
26_P	30_V	0.530	0.18
53_V	115_L	0.530	0.18
18_A	22_L	0.529	0.18
142_D	210_V	0.529	0.18
7_A	31_R	0.529	0.18
57_K	61_T	0.528	0.18
66_N	120_V	0.528	0.18
390_P	393_A	0.528	0.18
245_L	282_K	0.527	0.18
259_V	284_L	0.527	0.18
160_T	229_P	0.527	0.18
60_T	314_A	0.527	0.18
118_G	266_P	0.526	0.18
172_R	239_F	0.526	0.18
107_R	128_E	0.525	0.18
99_G	124_Q	0.525	0.18
160_T	224_G	0.525	0.18
17_R	26_P	0.525	0.18
142_D	153_K	0.524	0.18
242_G	246_E	0.522	0.18
74_V	78_M	0.521	0.18
263_V	400_F	0.520	0.18
120_V	335_L	0.520	0.18
103_D	107_R	0.519	0.17
65_V	89_W	0.519	0.17
31_R	399_Q	0.518	0.17
168_D	241_I	0.517	0.17
80_L	112_A	0.517	0.17
396_V	399_Q	0.517	0.17
339_K	391_Q	0.516	0.17
157_A	297_P	0.516	0.17
95_D	313_A	0.515	0.17
231_A	354_A	0.515	0.17
126_F	137_A	0.515	0.17
29_K	38_K	0.513	0.17
14_D	31_R	0.512	0.17
313_A	355_G	0.512	0.17
167_K	390_P	0.512	0.17
371_V	383_M	0.511	0.17
302_A	309_S	0.509	0.17
104_A	108_D	0.509	0.17
110_I	314_A	0.509	0.17
271_L	318_A	0.508	0.17
161_I	194_M	0.508	0.17
95_D	353_H	0.506	0.17
399_Q	416_P	0.503	0.17
12_I	84_K	0.502	0.17
414_Y	419_W	0.502	0.17
12_I	30_V	0.501	0.17
235_A	270_P	0.501	0.17
247_T	360_L	0.500	0.17

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4s28A	2	0.9838	100	0.039	Contact Map
3epoA	2	0.8984	100	0.039	Contact Map
1eyeA	2	0.4896	94.5	0.972	Contact Map
4muzA	2	0.4642	93.9	0.972	Contact Map
1aj0A	1	0.5612	93.4	0.973	Contact Map
2h9aB	1	0.5566	93	0.973	Contact Map
2dqwA	2	0.5012	92.9	0.973	Contact Map
4djdD	1	0.5612	91.8	0.974	Contact Map
2czdA	2	0.4596	91.7	0.974	Contact Map
3f4wA	2	0.4688	90.5	0.975	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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