GREMLIN Database
Q97X11 - Uncharacterized protein
UniProt: Q97X11 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 135 (132)
Sequences: 782 (564)
Seq/√Len: 49.1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
94_A106_H3.4651.00
112_F129_S3.3741.00
34_R59_E3.2491.00
87_D91_S3.0241.00
5_I18_G2.9161.00
58_L85_I2.8381.00
54_G71_L2.7841.00
116_G119_L2.6051.00
96_T104_A2.4311.00
84_G115_Q2.4221.00
65_S69_R2.3191.00
34_R56_S2.2511.00
17_V31_P2.2331.00
92_A108_V2.0851.00
79_E98_K2.0111.00
39_A86_V1.9540.99
109_G112_F1.9430.99
47_N75_D1.9100.99
107_I126_E1.8960.99
84_G113_T1.8400.99
29_F46_A1.7430.99
126_E130_Q1.7310.99
120_A124_V1.7020.98
107_I125_L1.6400.98
94_A108_V1.6380.98
68_I72_T1.6280.98
63_S66_D1.6240.98
64_A91_S1.5730.97
27_G31_P1.5710.97
44_A100_C1.5360.97
23_F46_A1.5270.97
68_I85_I1.5130.97
114_V129_S1.4860.96
101_Y118_I1.4670.96
19_V30_V1.4430.95
54_G67_T1.3640.94
64_A87_D1.3620.94
62_Y70_V1.3570.94
103_Y121_G1.3120.93
40_I54_G1.2940.92
5_I128_V1.2850.92
72_T83_V1.2790.92
56_S60_K1.2500.91
105_G125_L1.2360.90
24_L32_W1.2300.90
53_N74_S1.2220.90
70_V73_E1.2160.89
57_L62_Y1.2100.89
57_L71_L1.1810.88
32_W51_G1.1770.88
8_Y111_N1.1740.88
29_F48_L1.1650.87
128_V131_A1.1590.87
84_G94_A1.1300.85
67_T71_L1.1110.85
8_Y15_W1.0930.84
3_F128_V1.0720.82
49_T52_V1.0640.82
17_V41_A1.0250.79
53_N56_S1.0240.79
127_R130_Q1.0240.79
9_D14_A1.0230.79
87_D92_A1.0150.79
50_Y72_T1.0140.79
30_V41_A0.9920.77
54_G57_L0.9810.76
10_P111_N0.9790.76
72_T78_R0.9770.76
6_V86_V0.9710.76
36_N88_T0.9620.75
33_L41_A0.9610.75
66_D70_V0.9600.75
94_A113_T0.9490.74
7_I132_Q0.9470.74
42_T52_V0.9410.73
54_G85_I0.9280.72
40_I51_G0.9270.72
66_D69_R0.9170.71
34_R37_V0.9110.71
22_K44_A0.8930.69
57_L70_V0.8630.67
114_V128_V0.8500.65
33_L39_A0.8380.64
22_K46_A0.8310.64
63_S91_S0.8260.63
3_F20_A0.8140.62
37_V59_E0.8140.62
17_V39_A0.8080.61
15_W39_A0.8010.61
79_E99_E0.8000.61
96_T100_C0.7940.60
107_I129_S0.7940.60
64_A67_T0.7930.60
107_I112_F0.7900.60
58_L67_T0.7840.59
8_Y12_E0.7820.59
72_T75_D0.7780.59
9_D132_Q0.7730.58
100_C104_A0.7660.57
46_A115_Q0.7650.57
70_V74_S0.7610.57
10_P110_N0.7590.57
122_E126_E0.7510.56
37_V55_L0.7360.54
67_T85_I0.7350.54
116_G125_L0.7240.53
32_W42_T0.7190.53
40_I67_T0.7180.52
6_V84_G0.7140.52
24_L46_A0.7140.52
68_I83_V0.7100.52
45_L101_Y0.6980.50
129_S132_Q0.6900.50
6_V39_A0.6890.50
47_N54_G0.6880.49
105_G122_E0.6850.49
45_L100_C0.6840.49
9_D12_E0.6770.48
47_N71_L0.6760.48
20_A30_V0.6700.48
45_L102_S0.6650.47
57_L60_K0.6650.47
24_L101_Y0.6620.47
104_A115_Q0.6600.47
64_A93_A0.6570.46
22_K29_F0.6540.46
45_L80_K0.6540.46
21_S28_A0.6500.46
44_A101_Y0.6470.45
68_I93_A0.6450.45
103_Y120_A0.6440.45
5_I114_V0.6400.45
69_R72_T0.6370.44
44_A103_Y0.6360.44
19_V26_V0.6340.44
29_F44_A0.6310.44
7_I42_T0.6210.43
3_F24_L0.6190.42
62_Y66_D0.6190.42
63_S76_P0.6170.42
107_I114_V0.6160.42
7_I122_E0.6140.42
72_T76_P0.6130.42
75_D81_R0.6120.42
84_G104_A0.6110.42
38_G55_L0.6030.41
69_R89_K0.6000.41
3_F125_L0.5990.41
9_D50_Y0.5990.41
74_S78_R0.5970.40
78_R95_F0.5970.40
80_K101_Y0.5940.40
60_K98_K0.5930.40
23_F29_F0.5930.40
80_K99_E0.5890.40
30_V50_Y0.5890.40
89_K111_N0.5890.40
92_A113_T0.5810.39
110_N130_Q0.5710.38
49_T53_N0.5680.38
6_V41_A0.5670.37
33_L113_T0.5620.37
21_S44_A0.5620.37
69_R73_E0.5590.37
71_L78_R0.5590.37
84_G100_C0.5570.36
20_A128_V0.5560.36
23_F28_A0.5550.36
103_Y125_L0.5510.36
20_A25_A0.5510.36
15_W64_A0.5500.36
54_G58_L0.5500.36
24_L45_L0.5490.36
96_T103_Y0.5470.36
23_F50_Y0.5420.35
28_A48_L0.5390.35
21_S49_T0.5380.35
42_T100_C0.5370.35
106_H113_T0.5350.34
34_R55_L0.5330.34
41_A115_Q0.5320.34
44_A80_K0.5300.34
65_S73_E0.5260.34
127_R131_A0.5250.34
89_K130_Q0.5240.33
3_F115_Q0.5240.33
68_I127_R0.5230.33
15_W24_L0.5220.33
64_A85_I0.5200.33
24_L31_P0.5180.33
22_K101_Y0.5170.33
31_P42_T0.5160.33
21_S27_G0.5110.32
40_I83_V0.5100.32
67_T72_T0.5080.32
58_L78_R0.5070.32
73_E89_K0.5030.32
21_S29_F0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2imhA 2 0.9926 100 0.057 Contact Map
4pv2B 2 0.763 86.1 0.906 Contact Map
2gezB 2 0.763 81 0.911 Contact Map
1k2xB 2 0.837 78.5 0.914 Contact Map
1p4kA 2 0.8741 75.8 0.916 Contact Map
1apyB 2 0.8741 64.3 0.922 Contact Map
4o0cA 2 0.9111 59.2 0.925 Contact Map
3c17A 2 0.8593 57.7 0.925 Contact Map
3wu2O 1 0.3481 21.1 0.942 Contact Map
4pj0O 1 0.3481 20.7 0.942 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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