Q97WV3 - SULSO - GREMLIN Contacts

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Q97WV3 - N-methyl hydantoinase B (HyuB-2)

UniProt:	Q97WV3	Sequences: MTSWEIIHKAFEFIAEEMGVMLKRSAMSPNIRERMDHSCAILDAEGNIIAQAEHIPVHLGSFSVGVKNTLKIVNLEEGDMVILNDPYISGTHLNDVMLLAPIYYNGKLIGYVVNKAHHVDVGGPSPGSLNPYATTIYEEGLVIPPVKIIKKGKLNEEIVEIIRENFKVPEVSLGDLNAQISANLNGVLRVKQLIDKYGLDRVLSSWAKSIEYGRSLALSEISKWNEGSFEDEDYLELDTLKRIRVKITISDKGIIADFNGTDNQVEAPFNAVYGVTFSAVSFVVRSLIGKDIPTNEGFYSVIKVIAPEGTIVNPLKPAAVGGGNVETSQRIADVTFKAFSHSIPVPAASSGTMMNVMMGGTYKGKYWAYYETIGGGMGGRPNKDGVSGVHVNMTNTLNTPIEIAERHYPILFTTYRIREGSGGKGMYRGGDGIIRAFKVLEKTKLSIMAERFKVPPWGLKGGENGKPGRVTIIRKGNVVEEMPSKFSTILNPGDEVIIETPGGGGYGSEK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	510 (500)
Sequences:	2231 (1388)
Seq/√Len:	62.1

SULSO - Q97WV3 Q97UR7 Q97XP9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
413_T	438_K	5.827	1.00
253_G	303_K	4.643	1.00
76_E	151_K	4.595	1.00
382_N	427_Y	4.443	1.00
75_L	81_V	4.169	1.00
226_E	251_D	3.948	1.00
469_R	499_E	3.858	1.00
259_N	305_I	3.827	1.00
255_I	305_I	3.716	1.00
214_R	300_S	3.698	1.00
231_D	337_K	3.692	1.00
255_I	303_K	3.515	1.00
214_R	218_L	3.267	1.00
77_E	106_G	3.203	1.00
102_I	112_V	3.157	1.00
308_E	315_L	3.125	1.00
43_D	47_N	3.122	1.00
134_T	138_E	2.952	1.00
100_A	183_N	2.939	1.00
211_E	300_S	2.859	1.00
387_S	431_D	2.770	1.00
82_I	96_V	2.753	1.00
228_S	248_T	2.718	1.00
260_G	307_P	2.687	1.00
147_K	150_K	2.649	1.00
414_T	436_A	2.626	1.00
263_N	307_P	2.518	1.00
230_E	246_K	2.488	1.00
384_D	428_R	2.458	1.00
436_A	497_I	2.450	1.00
261_T	311_I	2.446	1.00
455_P	467_P	2.387	1.00
76_E	150_K	2.372	1.00
306_A	313_N	2.334	1.00
150_K	155_N	2.324	1.00
143_I	161_I	2.291	1.00
264_Q	318_A	2.263	1.00
438_K	495_E	2.259	1.00
189_R	192_Q	2.227	1.00
411_L	440_L	2.196	1.00
348_A	457_W	2.196	1.00
114_N	183_N	2.195	1.00
273_Y	306_A	2.182	1.00
413_T	436_A	2.166	1.00
442_K	492_P	2.164	1.00
17_E	189_R	2.112	1.00
135_T	138_E	2.109	1.00
388_G	417_I	2.090	1.00
307_P	313_N	2.090	1.00
218_L	253_G	2.077	1.00
474_R	480_E	2.040	1.00
424_K	463_E	2.000	1.00
232_E	244_R	1.991	1.00
245_V	256_A	1.945	1.00
434_I	499_E	1.942	1.00
360_G	441_E	1.937	1.00
326_E	352_T	1.933	1.00
72_I	160_E	1.916	1.00
228_S	246_K	1.914	1.00
194_I	202_V	1.905	1.00
10_A	196_K	1.881	1.00
75_L	111_Y	1.871	1.00
442_K	491_N	1.853	1.00
308_E	313_N	1.847	1.00
242_R	262_D	1.844	1.00
194_I	199_L	1.840	1.00
107_K	203_L	1.816	1.00
82_I	98_L	1.816	1.00
284_V	302_I	1.808	1.00
104_Y	195_D	1.794	1.00
436_A	495_E	1.792	1.00
226_E	252_K	1.791	1.00
424_K	428_R	1.773	1.00
356_V	445_L	1.768	0.99
471_T	479_V	1.767	0.99
222_S	251_D	1.767	0.99
226_E	249_I	1.761	0.99
118_H	179_Q	1.755	0.99
356_V	496_V	1.753	0.99
109_I	194_I	1.748	0.99
474_R	494_D	1.741	0.99
230_E	244_R	1.736	0.99
377_M	386_V	1.734	0.99
417_I	431_D	1.727	0.99
380_R	383_K	1.725	0.99
450_E	485_K	1.723	0.99
47_N	67_K	1.715	0.99
124_P	132_Y	1.709	0.99
469_R	481_E	1.709	0.99
232_E	242_R	1.707	0.99
384_D	427_Y	1.707	0.99
222_S	252_K	1.703	0.99
49_I	206_W	1.699	0.99
149_I	180_I	1.674	0.99
473_I	477_N	1.648	0.99
413_T	495_E	1.646	0.99
70_L	111_Y	1.631	0.99
31_I	116_A	1.630	0.99
166_F	169_P	1.628	0.99
472_I	490_L	1.622	0.99
210_I	300_S	1.622	0.99
248_T	251_D	1.608	0.99
460_K	506_Y	1.605	0.99
82_I	143_I	1.600	0.99
374_G	433_I	1.581	0.99
233_D	334_V	1.579	0.99
256_A	302_I	1.574	0.99
214_R	301_V	1.572	0.99
420_G	431_D	1.570	0.99
416_R	434_I	1.556	0.99
418_R	421_S	1.554	0.99
243_I	334_V	1.553	0.99
38_S	58_H	1.546	0.99
7_I	205_S	1.540	0.99
401_I	412_F	1.540	0.99
491_N	494_D	1.539	0.99
5_E	8_H	1.539	0.99
47_N	300_S	1.538	0.99
256_A	280_V	1.533	0.99
81_V	147_K	1.524	0.98
360_G	367_W	1.494	0.98
47_N	207_A	1.488	0.98
264_Q	315_L	1.487	0.98
224_W	229_F	1.480	0.98
158_I	161_I	1.474	0.98
100_A	187_V	1.463	0.98
107_K	199_L	1.433	0.98
355_N	370_Y	1.432	0.98
307_P	310_T	1.430	0.98
373_I	498_I	1.428	0.98
105_N	195_D	1.425	0.98
19_G	54_H	1.425	0.98
44_A	203_L	1.405	0.97
104_Y	108_L	1.402	0.97
219_S	222_S	1.385	0.97
220_E	223_K	1.378	0.97
124_P	138_E	1.378	0.97
457_W	464_N	1.375	0.97
286_S	336_F	1.367	0.97
80_M	100_A	1.364	0.97
156_E	160_E	1.355	0.97
208_K	211_E	1.351	0.97
419_E	431_D	1.348	0.97
87_Y	317_P	1.342	0.97
142_V	316_K	1.334	0.96
47_N	296_E	1.332	0.96
76_E	147_K	1.332	0.96
468_G	501_P	1.328	0.96
229_F	249_I	1.324	0.96
233_D	451_R	1.323	0.96
104_Y	109_I	1.318	0.96
253_G	301_V	1.313	0.96
411_L	438_K	1.309	0.96
47_N	210_I	1.305	0.96
473_I	497_I	1.303	0.96
263_N	310_T	1.303	0.96
264_Q	309_G	1.300	0.96
10_A	193_L	1.300	0.96
347_A	459_L	1.296	0.96
377_M	391_V	1.288	0.96
82_I	148_I	1.286	0.96
96_V	121_V	1.285	0.96
283_V	335_T	1.280	0.95
439_V	443_T	1.279	0.95
414_T	434_I	1.278	0.95
134_T	266_E	1.275	0.95
130_N	133_A	1.271	0.95
418_R	466_K	1.271	0.95
471_T	497_I	1.267	0.95
273_Y	313_N	1.261	0.95
310_T	313_N	1.256	0.95
282_F	392_N	1.255	0.95
240_L	262_D	1.252	0.95
148_I	180_I	1.246	0.95
247_I	256_A	1.246	0.95
191_K	195_D	1.244	0.95
150_K	153_K	1.238	0.95
473_I	476_G	1.236	0.95
348_A	351_G	1.235	0.95
475_K	494_D	1.234	0.94
187_V	191_K	1.231	0.94
102_I	187_V	1.229	0.94
472_I	488_T	1.224	0.94
141_L	162_I	1.224	0.94
235_L	269_F	1.215	0.94
249_I	252_K	1.212	0.94
199_L	203_L	1.204	0.94
104_Y	194_I	1.189	0.93
418_R	499_E	1.189	0.93
306_A	312_V	1.188	0.93
224_W	249_I	1.186	0.93
73_V	145_P	1.186	0.93
248_T	255_I	1.183	0.93
77_E	191_K	1.181	0.93
333_D	451_R	1.171	0.93
422_G	431_D	1.155	0.92
18_M	186_G	1.150	0.92
258_F	280_V	1.149	0.92
279_A	332_A	1.143	0.92
215_S	219_S	1.142	0.92
277_F	304_V	1.137	0.92
473_I	479_V	1.137	0.92
455_P	464_N	1.131	0.91
418_R	434_I	1.126	0.91
7_I	11_F	1.118	0.91
96_V	118_H	1.118	0.91
160_E	164_E	1.115	0.91
184_L	188_L	1.114	0.91
312_V	331_I	1.110	0.91
30_N	34_R	1.109	0.91
273_Y	277_F	1.107	0.91
80_M	149_I	1.105	0.90
67_K	296_E	1.105	0.90
337_K	457_W	1.104	0.90
471_T	499_E	1.103	0.90
330_R	450_E	1.102	0.90
211_E	214_R	1.100	0.90
221_I	249_I	1.097	0.90
218_L	301_V	1.087	0.90
226_E	229_F	1.085	0.90
420_G	424_K	1.083	0.90
102_I	190_V	1.077	0.89
429_G	502_G	1.077	0.89
264_Q	317_P	1.073	0.89
449_A	470_V	1.062	0.89
388_G	433_I	1.061	0.89
207_A	211_E	1.058	0.88
356_V	437_F	1.053	0.88
233_D	330_R	1.045	0.88
475_K	491_N	1.045	0.88
418_R	432_G	1.044	0.88
137_Y	316_K	1.041	0.88
109_I	199_L	1.040	0.88
202_V	206_W	1.039	0.88
159_V	170_E	1.036	0.87
80_M	183_N	1.032	0.87
472_I	482_M	1.030	0.87
193_L	197_Y	1.029	0.87
192_Q	196_K	1.028	0.87
146_V	158_I	1.028	0.87
104_Y	191_K	1.026	0.87
163_R	173_L	1.026	0.87
215_S	252_K	1.022	0.87
45_E	207_A	1.020	0.87
436_A	473_I	1.019	0.87
476_G	479_V	1.019	0.87
114_N	182_A	1.017	0.86
230_E	242_R	1.014	0.86
160_E	163_R	1.012	0.86
221_I	226_E	1.009	0.86
259_N	307_P	1.008	0.86
412_F	437_F	1.006	0.86
350_S	375_G	1.006	0.86
188_L	192_Q	1.003	0.86
85_D	144_P	1.003	0.86
70_L	108_L	1.001	0.86
258_F	331_I	0.994	0.85
268_P	319_A	0.993	0.85
158_I	163_R	0.989	0.85
341_H	345_V	0.982	0.84
398_N	415_Y	0.980	0.84
191_K	194_I	0.979	0.84
10_A	14_I	0.975	0.84
14_I	193_L	0.968	0.84
483_P	486_F	0.966	0.83
155_N	158_I	0.962	0.83
42_L	113_V	0.962	0.83
97_M	115_K	0.958	0.83
246_K	260_G	0.957	0.83
150_K	157_E	0.955	0.83
231_D	457_W	0.954	0.83
439_V	490_L	0.951	0.82
371_E	435_R	0.950	0.82
80_M	180_I	0.949	0.82
426_M	508_S	0.947	0.82
434_I	497_I	0.947	0.82
368_A	399_T	0.936	0.81
333_D	351_G	0.933	0.81
261_T	307_P	0.931	0.81
315_L	318_A	0.927	0.81
261_T	310_T	0.925	0.81
109_I	203_L	0.922	0.80
474_R	478_V	0.918	0.80
154_L	159_V	0.912	0.80
154_L	173_L	0.905	0.79
218_L	226_E	0.900	0.79
173_L	177_N	0.899	0.79
183_N	187_V	0.899	0.79
218_L	252_K	0.899	0.79
34_R	372_T	0.897	0.79
159_V	163_R	0.895	0.78
444_K	489_I	0.894	0.78
421_S	502_G	0.893	0.78
333_D	375_G	0.891	0.78
367_W	443_T	0.890	0.78
473_I	494_D	0.886	0.78
20_V	23_K	0.886	0.78
41_I	112_V	0.885	0.78
358_M	443_T	0.882	0.77
94_N	395_N	0.880	0.77
231_D	334_V	0.878	0.77
211_E	215_S	0.869	0.76
234_Y	454_V	0.865	0.76
61_S	91_T	0.864	0.76
280_V	304_V	0.864	0.76
67_K	71_K	0.860	0.76
214_R	253_G	0.855	0.75
77_E	187_V	0.854	0.75
221_I	229_F	0.853	0.75
226_E	250_S	0.844	0.74
133_A	319_A	0.841	0.74
69_T	81_V	0.841	0.74
75_L	108_L	0.837	0.74
265_V	269_F	0.837	0.74
261_T	312_V	0.836	0.74
185_N	189_R	0.832	0.73
108_L	111_Y	0.831	0.73
322_G	448_M	0.829	0.73
228_S	244_R	0.827	0.73
64_V	277_F	0.826	0.73
99_L	111_Y	0.822	0.72
146_V	161_I	0.819	0.72
63_S	296_E	0.818	0.72
428_R	431_D	0.814	0.72
82_I	158_I	0.812	0.71
404_A	412_F	0.811	0.71
347_A	378_G	0.811	0.71
239_T	262_D	0.809	0.71
474_R	477_N	0.808	0.71
340_S	460_K	0.808	0.71
163_R	170_E	0.802	0.70
85_D	145_P	0.801	0.70
463_E	505_G	0.797	0.70
71_K	77_E	0.796	0.70
146_V	155_N	0.794	0.70
58_H	61_S	0.788	0.69
195_D	222_S	0.788	0.69
292_I	298_F	0.788	0.69
148_I	155_N	0.782	0.68
237_L	485_K	0.774	0.68
471_T	481_E	0.773	0.68
381_P	427_Y	0.773	0.68
166_F	172_S	0.772	0.67
85_D	142_V	0.771	0.67
384_D	508_S	0.770	0.67
213_G	217_A	0.770	0.67
136_I	317_P	0.766	0.67
210_I	214_R	0.765	0.67
260_G	263_N	0.765	0.67
22_L	116_A	0.762	0.66
359_G	370_Y	0.762	0.66
38_S	51_Q	0.760	0.66
446_S	487_S	0.760	0.66
275_V	324_N	0.760	0.66
147_K	155_N	0.760	0.66
353_M	393_M	0.756	0.66
216_L	289_G	0.754	0.66
234_Y	242_R	0.754	0.66
445_L	496_V	0.753	0.66
210_I	296_E	0.752	0.65
98_L	180_I	0.750	0.65
337_K	348_A	0.749	0.65
61_S	65_G	0.749	0.65
64_V	274_G	0.747	0.65
98_L	183_N	0.747	0.65
184_L	187_V	0.747	0.65
276_T	306_A	0.747	0.65
21_M	185_N	0.743	0.65
281_S	299_Y	0.741	0.64
227_G	249_I	0.737	0.64
65_G	83_L	0.737	0.64
230_E	426_M	0.736	0.64
375_G	378_G	0.734	0.64
314_P	318_A	0.733	0.63
451_R	456_P	0.732	0.63
185_N	188_L	0.732	0.63
23_K	37_H	0.731	0.63
235_L	450_E	0.728	0.63
5_E	9_K	0.727	0.63
73_V	81_V	0.726	0.63
260_G	306_A	0.725	0.63
420_G	508_S	0.724	0.63
428_R	505_G	0.723	0.62
79_D	147_K	0.723	0.62
218_L	251_D	0.721	0.62
212_Y	216_L	0.721	0.62
232_E	240_L	0.721	0.62
240_L	454_V	0.719	0.62
112_V	187_V	0.719	0.62
366_Y	441_E	0.715	0.62
34_R	390_H	0.714	0.61
71_K	105_N	0.713	0.61
79_D	151_K	0.712	0.61
32_R	407_H	0.712	0.61
27_M	174_G	0.711	0.61
228_S	250_S	0.711	0.61
24_R	496_V	0.710	0.61
436_A	499_E	0.708	0.61
89_S	274_G	0.707	0.61
378_G	503_G	0.704	0.60
213_G	295_N	0.704	0.60
256_A	284_V	0.703	0.60
241_K	311_I	0.697	0.60
3_S	201_R	0.696	0.59
215_S	222_S	0.695	0.59
18_M	39_C	0.694	0.59
186_G	335_T	0.694	0.59
30_N	372_T	0.693	0.59
367_W	441_E	0.691	0.59
42_L	62_F	0.691	0.59
163_R	166_F	0.691	0.59
454_V	467_P	0.690	0.59
284_V	339_F	0.690	0.59
230_E	240_L	0.688	0.59
360_G	366_Y	0.687	0.58
445_L	490_L	0.686	0.58
415_Y	435_R	0.686	0.58
154_L	177_N	0.686	0.58
272_V	314_P	0.686	0.58
158_I	475_K	0.684	0.58
438_K	493_G	0.683	0.58
3_S	197_Y	0.683	0.58
198_G	201_R	0.682	0.58
100_A	114_N	0.681	0.58
21_M	25_S	0.680	0.58
143_I	148_I	0.680	0.58
459_L	506_Y	0.679	0.58
238_D	485_K	0.676	0.57
253_G	300_S	0.675	0.57
65_G	272_V	0.674	0.57
70_L	75_L	0.674	0.57
217_A	272_V	0.674	0.57
382_N	426_M	0.672	0.57
472_I	496_V	0.670	0.57
54_H	58_H	0.670	0.57
105_N	250_S	0.670	0.57
250_S	255_I	0.669	0.56
74_N	147_K	0.666	0.56
56_P	60_G	0.665	0.56
143_I	146_V	0.665	0.56
68_N	71_K	0.665	0.56
241_K	265_V	0.663	0.56
46_G	70_L	0.658	0.55
330_R	456_P	0.658	0.55
69_T	99_L	0.658	0.55
104_Y	107_K	0.657	0.55
153_K	453_K	0.655	0.55
381_P	506_Y	0.655	0.55
378_G	429_G	0.654	0.55
105_N	424_K	0.654	0.55
93_L	140_G	0.653	0.55
352_T	501_P	0.651	0.54
200_D	204_S	0.649	0.54
149_I	154_L	0.649	0.54
26_A	333_D	0.648	0.54
71_K	331_I	0.648	0.54
77_E	151_K	0.647	0.54
102_I	186_G	0.647	0.54
102_I	110_G	0.646	0.54
153_K	250_S	0.645	0.54
241_K	334_V	0.643	0.54
334_V	451_R	0.642	0.53
34_R	396_T	0.642	0.53
104_Y	199_L	0.641	0.53
229_F	252_K	0.640	0.53
225_N	249_I	0.640	0.53
125_S	132_Y	0.639	0.53
427_Y	495_E	0.639	0.53
44_A	70_L	0.639	0.53
71_K	195_D	0.638	0.53
249_I	254_I	0.638	0.53
23_K	35_M	0.637	0.53
55_I	396_T	0.636	0.53
114_N	179_Q	0.636	0.53
351_G	451_R	0.635	0.53
372_T	396_T	0.635	0.53
118_H	395_N	0.632	0.52
305_I	308_E	0.632	0.52
481_E	499_E	0.631	0.52
41_I	190_V	0.631	0.52
269_F	319_A	0.630	0.52
222_S	253_G	0.630	0.52
19_G	37_H	0.630	0.52
44_A	107_K	0.629	0.52
122_G	167_K	0.629	0.52
458_G	464_N	0.628	0.52
477_N	480_E	0.628	0.52
220_E	224_W	0.627	0.52
458_G	462_G	0.627	0.52
6_I	197_Y	0.627	0.52
57_V	393_M	0.626	0.52
220_E	288_I	0.624	0.51
38_S	59_L	0.623	0.51
112_V	186_G	0.621	0.51
271_A	323_G	0.620	0.51
42_L	48_I	0.619	0.51
325_V	370_Y	0.617	0.51
275_V	323_G	0.617	0.51
25_S	37_H	0.617	0.51
473_I	495_E	0.616	0.50
161_I	165_N	0.614	0.50
57_V	279_A	0.613	0.50
380_R	386_V	0.611	0.50
147_K	151_K	0.610	0.50
181_S	295_N	0.610	0.50
455_P	466_K	0.609	0.50
4_W	7_I	0.608	0.50
326_E	370_Y	0.608	0.50
151_K	228_S	0.607	0.49
259_N	308_E	0.605	0.49
151_K	188_L	0.605	0.49
285_R	290_K	0.604	0.49
292_I	307_P	0.604	0.49
159_V	169_P	0.604	0.49
137_Y	166_F	0.603	0.49
59_L	395_N	0.601	0.49
330_R	333_D	0.600	0.49
275_V	328_S	0.600	0.49
103_Y	108_L	0.598	0.48
107_K	200_D	0.597	0.48
160_E	308_E	0.597	0.48
87_Y	91_T	0.597	0.48
21_M	188_L	0.596	0.48
200_D	489_I	0.596	0.48
426_M	460_K	0.595	0.48
87_Y	186_G	0.594	0.48
157_E	195_D	0.594	0.48
242_R	453_K	0.592	0.48
71_K	88_I	0.592	0.48
188_L	191_K	0.592	0.48
231_D	338_A	0.592	0.48
369_Y	437_F	0.590	0.47
296_E	300_S	0.590	0.47
222_S	226_E	0.590	0.47
56_P	62_F	0.589	0.47
355_N	359_G	0.588	0.47
11_F	206_W	0.588	0.47
195_D	492_P	0.587	0.47
201_R	205_S	0.585	0.47
490_L	494_D	0.584	0.47
65_G	68_N	0.584	0.47
223_K	226_E	0.583	0.47
35_M	53_E	0.583	0.47
21_M	100_A	0.583	0.47
29_P	51_Q	0.583	0.47
67_K	70_L	0.582	0.47
44_A	108_L	0.582	0.47
444_K	487_S	0.582	0.47
145_P	198_G	0.581	0.46
14_I	278_S	0.581	0.46
69_T	83_L	0.580	0.46
197_Y	202_V	0.580	0.46
105_N	200_D	0.580	0.46
246_K	259_N	0.580	0.46
137_Y	169_P	0.580	0.46
216_L	219_S	0.580	0.46
271_A	276_T	0.576	0.46
11_F	202_V	0.576	0.46
223_K	453_K	0.576	0.46
371_E	396_T	0.576	0.46
48_I	299_Y	0.575	0.46
371_E	395_N	0.575	0.46
239_T	311_I	0.574	0.46
151_K	160_E	0.574	0.46
471_T	490_L	0.574	0.46
335_T	486_F	0.573	0.46
96_V	143_I	0.573	0.46
390_H	394_T	0.572	0.45
129_L	325_V	0.572	0.45
117_H	175_D	0.571	0.45
257_D	305_I	0.571	0.45
353_M	372_T	0.571	0.45
26_A	33_E	0.571	0.45
110_G	202_V	0.571	0.45
151_K	315_L	0.570	0.45
41_I	102_I	0.569	0.45
374_G	388_G	0.569	0.45
66_V	99_L	0.568	0.45
354_M	468_G	0.568	0.45
35_M	407_H	0.567	0.45
197_Y	225_N	0.566	0.45
72_I	88_I	0.566	0.45
125_S	130_N	0.566	0.45
228_S	232_E	0.566	0.45
80_M	98_L	0.566	0.45
251_D	255_I	0.564	0.45
85_D	88_I	0.564	0.45
332_A	393_M	0.564	0.45
118_H	285_R	0.564	0.45
105_N	191_K	0.563	0.44
157_E	160_E	0.563	0.44
379_G	422_G	0.563	0.44
55_I	349_S	0.562	0.44
195_D	200_D	0.560	0.44
256_A	339_F	0.560	0.44
222_S	508_S	0.557	0.44
99_L	113_V	0.556	0.44
142_V	145_P	0.556	0.44
40_A	54_H	0.556	0.44
65_G	111_Y	0.556	0.44
356_V	373_I	0.555	0.44
207_A	250_S	0.555	0.44
107_K	464_N	0.554	0.43
384_D	505_G	0.554	0.43
4_W	208_K	0.553	0.43
351_G	456_P	0.553	0.43
273_Y	308_E	0.552	0.43
180_I	184_L	0.551	0.43
31_I	396_T	0.550	0.43
2_T	173_L	0.549	0.43
156_E	173_L	0.549	0.43
46_G	123_G	0.549	0.43
8_H	12_E	0.549	0.43
354_M	452_F	0.548	0.43
324_N	328_S	0.548	0.43
6_I	325_V	0.548	0.43
166_F	171_V	0.548	0.43
279_A	335_T	0.547	0.43
474_R	491_N	0.547	0.43
87_Y	144_P	0.547	0.43
120_D	450_E	0.547	0.43
428_R	463_E	0.546	0.42
244_R	260_G	0.546	0.42
245_V	334_V	0.546	0.42
230_E	341_H	0.545	0.42
474_R	479_V	0.545	0.42
81_V	224_W	0.545	0.42
463_E	508_S	0.545	0.42
421_S	431_D	0.545	0.42
415_Y	433_I	0.545	0.42
450_E	484_S	0.544	0.42
159_V	173_L	0.544	0.42
31_I	390_H	0.544	0.42
212_Y	215_S	0.543	0.42
190_V	194_I	0.542	0.42
271_A	275_V	0.541	0.42
249_I	303_K	0.541	0.42
156_E	177_N	0.541	0.42
443_T	490_L	0.541	0.42
227_G	246_K	0.540	0.42
16_E	19_G	0.539	0.42
73_V	150_K	0.538	0.42
282_F	329_Q	0.538	0.42
106_G	110_G	0.537	0.41
22_L	114_N	0.535	0.41
69_T	73_V	0.535	0.41
137_Y	360_G	0.535	0.41
416_R	426_M	0.535	0.41
79_D	103_Y	0.535	0.41
197_Y	247_I	0.534	0.41
466_K	499_E	0.534	0.41
38_S	278_S	0.534	0.41
144_P	227_G	0.534	0.41
76_E	106_G	0.533	0.41
224_W	278_S	0.533	0.41
255_I	259_N	0.533	0.41
433_I	455_P	0.533	0.41
325_V	357_M	0.532	0.41
71_K	107_K	0.532	0.41
104_Y	188_L	0.532	0.41
260_G	313_N	0.532	0.41
258_F	307_P	0.531	0.41
296_E	302_I	0.528	0.40
124_P	130_N	0.527	0.40
171_V	446_S	0.527	0.40
269_F	311_I	0.527	0.40
441_E	492_P	0.526	0.40
37_H	53_E	0.526	0.40
449_A	486_F	0.526	0.40
100_A	184_L	0.526	0.40
23_K	48_I	0.526	0.40
379_G	427_Y	0.526	0.40
44_A	250_S	0.525	0.40
276_T	283_V	0.525	0.40
155_N	160_E	0.524	0.40
34_R	394_T	0.524	0.40
67_K	223_K	0.523	0.40
106_G	246_K	0.523	0.40
123_G	295_N	0.523	0.40
29_P	408_Y	0.523	0.40
107_K	153_K	0.521	0.40
71_K	76_E	0.521	0.40
279_A	328_S	0.521	0.40
245_V	338_A	0.519	0.40
15_A	50_A	0.518	0.39
33_E	36_D	0.518	0.39
330_R	451_R	0.518	0.39
2_T	8_H	0.518	0.39
113_V	333_D	0.518	0.39
285_R	322_G	0.518	0.39
503_G	507_G	0.516	0.39
222_S	249_I	0.515	0.39
479_V	483_P	0.515	0.39
105_N	153_K	0.515	0.39
121_V	182_A	0.514	0.39
238_D	267_A	0.514	0.39
89_S	94_N	0.514	0.39
19_G	52_A	0.514	0.39
377_M	387_S	0.514	0.39
348_A	451_R	0.514	0.39
233_D	457_W	0.514	0.39
403_I	407_H	0.513	0.39
125_S	133_A	0.513	0.39
153_K	427_Y	0.513	0.39
217_A	298_F	0.513	0.39
22_L	30_N	0.513	0.39
170_E	184_L	0.512	0.39
24_R	85_D	0.512	0.39
105_N	228_S	0.511	0.39
170_E	223_K	0.511	0.39
258_F	312_V	0.511	0.39
452_F	470_V	0.511	0.39
77_E	107_K	0.510	0.39
28_S	116_A	0.510	0.39
18_M	37_H	0.510	0.39
201_R	204_S	0.510	0.39
476_G	506_Y	0.510	0.39
447_I	496_V	0.510	0.39
302_I	334_V	0.509	0.38
244_R	259_N	0.509	0.38
174_G	400_P	0.509	0.38
254_I	284_V	0.509	0.38
222_S	250_S	0.508	0.38
389_V	395_N	0.508	0.38
271_A	324_N	0.508	0.38
375_G	429_G	0.508	0.38
231_D	455_P	0.507	0.38
82_I	146_V	0.507	0.38
38_S	56_P	0.506	0.38
248_T	252_K	0.506	0.38
376_G	432_G	0.506	0.38
129_L	321_G	0.506	0.38
172_S	403_I	0.505	0.38
440_L	492_P	0.505	0.38
32_R	395_N	0.505	0.38
256_A	335_T	0.504	0.38
192_Q	506_Y	0.504	0.38
333_D	348_A	0.504	0.38
129_L	268_P	0.503	0.38
245_V	258_F	0.503	0.38
120_D	131_P	0.502	0.38
170_E	173_L	0.502	0.38
156_E	159_V	0.502	0.38
402_E	405_E	0.501	0.38
141_L	165_N	0.501	0.38
476_G	480_E	0.501	0.38
217_A	292_I	0.501	0.38
119_V	370_Y	0.501	0.38
149_I	152_G	0.500	0.37
378_G	502_G	0.500	0.37

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2kzxA	1	0.2294	46.2	0.979	Contact Map
1j5kA	1	0.1294	29.6	0.981	Contact Map
3o6uA	1	0.2333	25.8	0.982	Contact Map
2yfqA	5	0.3627	22.9	0.982	Contact Map
2oa5A	4	0.1706	16.7	0.983	Contact Map
3aoeE	3	0.3902	15.5	0.984	Contact Map
1p0zA	4	0.2157	13.7	0.984	Contact Map
3by8A	2	0.2275	13.4	0.984	Contact Map
3k92A	5	0.4118	11.5	0.985	Contact Map
4e2xA	1	0.2706	10	0.985	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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