GREMLIN Database
Q97WU6 - Ring oxydation complex/ phenylacetic acid degradation related protein
UniProt: Q97WU6 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 256 (213)
Sequences: 1402 (695)
Seq/√Len: 47.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
189_Q193_N4.3191.00
99_K102_A3.9081.00
47_G88_I3.7521.00
38_V213_L3.3401.00
45_V208_S3.1611.00
54_I81_M3.0371.00
69_D171_F3.0191.00
189_Q245_E3.0111.00
115_L202_M2.9911.00
55_E58_M2.8581.00
134_L192_I2.7211.00
185_R243_G2.6201.00
120_I198_R2.5391.00
214_A220_K2.4941.00
181_E243_G2.4401.00
126_E191_L2.4171.00
130_G188_A2.4121.00
185_R189_Q2.3851.00
176_I188_A2.3041.00
205_H223_R2.1621.00
133_F176_I2.1431.00
137_R169_I2.1001.00
87_V154_L2.0351.00
90_I153_P2.0100.99
92_K98_G1.9930.99
41_K113_H1.9790.99
236_K246_L1.9530.99
199_G231_Y1.9510.99
87_V143_L1.8960.99
124_M187_L1.8750.99
143_L165_E1.7780.99
129_L176_I1.7110.98
40_F94_F1.7070.98
90_I151_F1.6820.98
130_G192_I1.6490.98
205_H225_D1.6050.97
124_M127_D1.6020.97
180_V188_A1.5980.97
88_I103_E1.5960.97
186_D190_A1.5730.97
74_S81_M1.5710.97
85_W100_K1.5590.97
127_D194_K1.5390.97
236_K240_T1.5350.97
211_I214_A1.5170.96
228_R232_I1.5110.96
64_A125_W1.5010.96
136_D139_G1.4870.96
101_I107_S1.4570.95
223_R226_E1.4200.95
143_L171_F1.4150.94
189_Q243_G1.4110.94
133_F238_L1.3930.94
140_M162_M1.3910.94
189_Q239_I1.3790.94
92_K95_G1.3760.94
141_F234_D1.3660.93
152_G156_R1.3610.93
145_A230_L1.3480.93
108_R111_G1.3440.93
212_D216_K1.3320.92
133_F172_G1.2990.92
133_F235_I1.2770.91
43_L94_F1.2710.91
237_E241_P1.2620.90
130_G176_I1.2470.90
232_I236_K1.2450.90
139_G165_E1.2420.90
134_L195_W1.2390.89
209_I212_D1.2390.89
173_Y238_L1.2180.89
118_F135_I1.2110.88
102_A106_L1.2070.88
56_Q59_P1.2030.88
86_Q157_I1.1930.88
53_S131_F1.1870.87
162_M166_E1.1660.86
80_E165_E1.1640.86
104_D107_S1.1500.86
137_R141_F1.1320.85
200_L228_R1.1180.84
148_D216_K1.1120.84
188_A244_L1.1020.83
115_L135_I1.1010.83
228_R231_Y1.0970.83
39_L43_L1.0930.83
87_V139_G1.0860.82
180_V242_L1.0840.82
101_I105_L1.0780.82
111_G248_D1.0690.81
50_E165_E1.0650.81
90_I93_E1.0630.81
212_D223_R1.0630.81
196_F247_P1.0630.81
145_A226_E1.0570.80
229_Q232_I1.0520.80
44_S96_E1.0510.80
136_D143_L1.0460.80
176_I238_L1.0450.80
139_G143_L1.0400.79
137_R234_D1.0330.79
45_V210_T1.0240.78
180_V185_R1.0180.78
49_T115_L1.0170.78
53_S132_T1.0040.77
225_D229_Q1.0010.77
173_Y234_D1.0000.77
101_I104_D0.9990.76
136_D172_G0.9980.76
51_F112_R0.9970.76
39_L214_A0.9920.76
80_E136_D0.9910.76
144_L147_E0.9700.74
136_D171_F0.9660.74
170_N174_T0.9630.74
134_L235_I0.9590.73
117_A135_I0.9520.73
180_V189_Q0.9490.73
56_Q68_S0.9440.72
49_T139_G0.9370.72
92_K99_K0.9320.71
103_E107_S0.9300.71
190_A193_N0.9300.71
160_T167_F0.9210.70
98_G102_A0.9170.70
80_E139_G0.9090.69
45_V211_I0.9070.69
217_Y248_D0.9040.69
49_T214_A0.8940.68
120_I194_K0.8880.68
232_I246_L0.8870.67
208_S211_I0.8870.67
190_A194_K0.8800.67
89_Q100_K0.8740.66
246_L249_I0.8720.66
109_R113_H0.8720.66
129_L175_G0.8700.66
79_D191_L0.8690.66
113_H117_A0.8680.66
140_M166_E0.8640.65
173_Y177_K0.8620.65
76_I171_F0.8540.65
140_M144_L0.8460.64
175_G178_K0.8400.63
85_W156_R0.8370.63
93_E153_P0.8330.63
231_Y235_I0.8210.61
144_L233_K0.8210.61
169_I234_D0.8170.61
58_M74_S0.8140.61
60_W123_N0.8130.61
186_D233_K0.7960.59
95_G99_K0.7890.58
193_N239_I0.7760.57
128_T132_T0.7750.57
130_G191_L0.7670.56
225_D228_R0.7670.56
82_R164_E0.7660.56
138_V142_Q0.7650.56
153_P156_R0.7640.56
79_D160_T0.7590.55
107_S114_K0.7490.54
62_I70_R0.7480.54
58_M77_M0.7460.54
83_H151_F0.7450.54
138_V166_E0.7450.54
125_W179_L0.7400.54
124_M191_L0.7390.53
85_W89_Q0.7390.53
41_K210_T0.7390.53
171_F175_G0.7390.53
169_I173_Y0.7250.52
75_R78_V0.7240.52
141_F230_L0.7220.52
139_G171_F0.7210.52
188_A243_G0.7190.51
136_D219_I0.7190.51
54_I135_I0.7190.51
128_T157_I0.7170.51
115_L118_F0.7170.51
192_I237_E0.7160.51
183_G196_F0.7110.51
140_M234_D0.7100.51
120_I127_D0.7100.51
94_F217_Y0.7070.50
114_K119_N0.7070.50
138_V143_L0.7060.50
213_L229_Q0.6930.49
141_F227_M0.6930.49
87_V171_F0.6920.49
148_D190_A0.6920.49
107_S113_H0.6850.48
66_K125_W0.6810.48
132_T136_D0.6810.48
177_K242_L0.6770.47
51_F104_D0.6760.47
89_Q92_K0.6730.47
194_K197_P0.6680.46
43_L153_P0.6670.46
87_V136_D0.6640.46
171_F174_T0.6630.46
70_R74_S0.6630.46
89_Q192_I0.6590.45
64_A71_V0.6580.45
122_F128_T0.6570.45
224_N229_Q0.6560.45
215_Y223_R0.6550.45
50_E80_E0.6490.44
157_I161_M0.6460.44
193_N245_E0.6460.44
78_V82_R0.6430.44
126_E179_L0.6430.44
76_I154_L0.6390.43
226_E229_Q0.6390.43
80_E83_H0.6380.43
166_E169_I0.6380.43
49_T124_M0.6370.43
53_S118_F0.6350.43
107_S111_G0.6340.43
177_K241_P0.6300.43
79_D167_F0.6280.42
151_F161_M0.6280.42
50_E249_I0.6270.42
160_T179_L0.6260.42
210_T213_L0.6250.42
205_H212_D0.6200.42
50_E83_H0.6190.42
142_Q165_E0.6170.41
200_L204_G0.6160.41
40_F43_L0.6150.41
66_K171_F0.6150.41
179_L188_A0.6140.41
77_M81_M0.6140.41
82_R167_F0.6090.41
239_I246_L0.6080.40
125_W151_F0.6070.40
132_T172_G0.6060.40
192_I239_I0.6050.40
116_D132_T0.6040.40
117_A239_I0.6040.40
57_H125_W0.6010.40
238_L242_L0.5990.40
216_K248_D0.5970.39
140_M169_I0.5960.39
66_K71_V0.5950.39
54_I142_Q0.5940.39
205_H224_N0.5890.39
74_S77_M0.5880.39
92_K100_K0.5860.38
127_D195_W0.5850.38
229_Q236_K0.5820.38
61_L174_T0.5780.38
217_Y221_K0.5780.38
234_D237_E0.5750.37
205_H226_E0.5740.37
40_F98_G0.5740.37
148_D240_T0.5720.37
43_L90_I0.5660.36
64_A74_S0.5620.36
50_E139_G0.5610.36
66_K69_D0.5590.36
41_K45_V0.5590.36
52_A121_P0.5540.35
39_L94_F0.5530.35
101_I167_F0.5490.35
61_L86_Q0.5490.35
193_N248_D0.5480.35
83_H165_E0.5470.35
102_A109_R0.5470.35
54_I138_V0.5460.35
155_S227_M0.5460.35
70_R77_M0.5450.35
70_R131_F0.5440.34
54_I58_M0.5410.34
144_L148_D0.5400.34
75_R160_T0.5400.34
42_L221_K0.5390.34
82_R160_T0.5390.34
127_D191_L0.5380.34
109_R200_L0.5370.34
229_Q248_D0.5350.34
79_D136_D0.5350.34
58_M128_T0.5350.34
92_K102_A0.5350.34
118_F180_V0.5330.33
245_E250_N0.5330.33
127_D250_N0.5330.33
134_L199_G0.5320.33
190_A245_E0.5320.33
238_L241_P0.5290.33
64_A80_E0.5280.33
72_T179_L0.5280.33
122_F127_D0.5280.33
99_K198_R0.5270.33
39_L90_I0.5270.33
213_L217_Y0.5260.33
180_V244_L0.5250.33
75_R164_E0.5230.33
90_I132_T0.5230.33
107_S112_R0.5210.32
99_K225_D0.5210.32
171_F231_Y0.5210.32
160_T191_L0.5200.32
144_L230_L0.5180.32
203_F228_R0.5180.32
203_F227_M0.5180.32
39_L83_H0.5170.32
147_E159_P0.5170.32
45_V231_Y0.5150.32
57_H77_M0.5140.32
157_I160_T0.5130.32
68_S160_T0.5110.32
43_L47_G0.5090.31
57_H81_M0.5080.31
50_E66_K0.5070.31
240_T245_E0.5050.31
42_L55_E0.5030.31
149_S158_I0.5020.31
159_P166_E0.5010.31
49_T84_G0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1otkA 2 0.8516 100 0.197 Contact Map
3pf7A 1 0.9844 100 0.204 Contact Map
3pvtA 1 0.9688 100 0.255 Contact Map
4mudA 2 0.8633 100 0.316 Contact Map
3ge3A 2 0.9766 98.9 0.849 Contact Map
2incA 2 0.9766 98.9 0.85 Contact Map
1mtyB 2 0.9531 98.5 0.867 Contact Map
3u52A 2 0.9648 98.3 0.874 Contact Map
1mtyD 2 0.957 98.3 0.875 Contact Map
3ez0A 2 0.8203 98.2 0.877 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0088 seconds.