GREMLIN Database
Q97WU5 - Ring oxydation complex/ phenylacetic acid degradation related protein
UniProt: Q97WU5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 234 (203)
Sequences: 1351 (697)
Seq/√Len: 48.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
77_D80_V4.9771.00
163_Q167_N4.2411.00
26_A67_V3.9291.00
24_L180_V3.4311.00
17_T187_H3.2851.00
92_L176_M2.9411.00
48_D148_F2.8811.00
163_Q219_V2.8411.00
111_L166_L2.7951.00
33_V60_L2.7541.00
107_A162_L2.7201.00
34_E37_S2.6741.00
97_M172_R2.5361.00
159_K217_G2.5281.00
188_L194_S2.4291.00
103_E165_A2.3541.00
159_K163_Q2.2911.00
20_E90_H2.1871.00
153_L162_L2.1751.00
110_F153_L2.1651.00
74_N78_R2.1041.00
173_A205_Y2.0861.00
179_K197_I2.0581.00
66_L131_L2.0541.00
75_V80_V2.0031.00
69_L130_P1.9470.99
114_R146_L1.9300.99
66_L120_L1.8860.99
74_N77_D1.8850.99
101_N161_R1.7780.99
210_N220_E1.7330.99
106_I153_L1.6810.98
120_L142_E1.6630.98
69_L128_F1.6590.98
22_I73_F1.6010.98
107_A166_L1.5440.97
202_I206_V1.5060.96
75_V78_R1.4990.96
113_D116_G1.4960.96
101_N104_D1.4720.96
186_V190_D1.4680.96
160_N164_A1.4650.96
53_A60_L1.4620.96
104_D168_F1.4230.95
197_I200_K1.4170.95
170_F221_V1.4010.95
179_K199_D1.3710.94
43_A102_W1.3700.94
129_E133_N1.3700.94
122_V204_D1.3620.94
74_N79_V1.3600.94
210_N214_R1.3550.94
110_F149_S1.3450.93
110_F212_E1.3450.93
163_Q217_G1.3380.93
157_Q160_N1.3350.93
163_Q213_M1.3260.93
185_E188_L1.3160.93
35_Q38_P1.3140.93
19_I73_F1.3060.92
120_L148_F1.2990.92
24_L182_S1.2960.92
117_L139_I1.2900.92
111_L169_W1.2830.92
116_G142_E1.2580.91
95_S112_V1.2580.91
206_V210_N1.2490.90
110_F209_T1.2440.90
85_A88_G1.2380.90
118_Y208_S1.2360.90
71_E79_V1.2340.90
181_K186_V1.2000.89
211_D215_N1.1920.88
28_F92_L1.1800.88
59_E142_E1.1760.88
71_E78_R1.1740.88
203_E206_V1.1670.87
65_Q134_L1.1620.87
32_M108_F1.1600.87
75_V79_V1.1270.85
107_A153_L1.1260.85
92_L112_V1.1150.85
18_L188_L1.1150.85
157_Q161_R1.1120.84
202_I205_Y1.1010.84
150_K212_E1.0760.82
32_M109_V1.0660.82
72_E130_P1.0560.81
174_L202_I1.0360.80
69_L72_E1.0330.80
162_L218_F1.0320.80
114_R118_Y1.0170.79
122_V200_K1.0080.78
116_G120_L1.0050.78
162_L217_G0.9980.77
94_I112_V0.9940.77
139_I143_E0.9840.76
30_L89_I0.9800.76
29_E142_E0.9760.76
114_R208_S0.9730.76
66_L116_G0.9730.76
113_D148_F0.9690.75
91_M96_N0.9680.75
59_E113_D0.9630.75
153_L212_E0.9540.74
113_D120_L0.9510.74
19_I74_N0.9430.73
113_D149_S0.9400.73
150_K154_K0.9400.73
150_K208_S0.9380.73
117_L121_R0.9250.72
199_D203_E0.9250.72
147_F151_N0.9230.72
107_A165_A0.9200.71
23_V75_V0.9110.71
59_E116_G0.9100.71
106_I152_V0.9100.71
18_L22_I0.8970.69
58_D165_A0.8940.69
121_R124_K0.8920.69
152_V155_A0.8890.69
105_V109_V0.8890.69
164_A167_N0.8850.68
111_L209_T0.8850.68
206_V220_E0.8700.67
101_N157_Q0.8650.67
199_D202_I0.8650.67
28_F116_G0.8540.66
137_S144_S0.8460.65
74_N80_V0.8440.65
97_M168_F0.8430.65
92_L95_S0.8410.64
125_D190_D0.8380.64
164_A168_F0.8370.64
35_Q47_D0.8270.63
64_W80_V0.8230.63
205_Y209_T0.8220.63
68_R166_L0.8160.62
55_L148_F0.8140.62
37_S53_A0.8070.61
49_R53_A0.8030.61
187_H190_D0.7960.60
117_L143_E0.7960.60
146_L208_S0.7950.60
73_F76_K0.7920.60
71_E75_V0.7920.60
61_N141_E0.7890.59
130_P133_N0.7890.59
101_N165_A0.7870.59
188_L193_V0.7850.59
117_L208_S0.7770.58
31_G98_P0.7730.58
68_R71_E0.7700.58
64_W133_N0.7660.57
121_R207_R0.7600.57
134_L138_M0.7540.56
48_D157_Q0.7540.56
41_V49_R0.7530.56
115_A119_Q0.7510.56
97_M104_D0.7470.55
200_K203_E0.7460.55
160_N207_R0.7430.55
174_L178_Y0.7290.54
37_S56_V0.7270.53
113_D193_V0.7260.53
64_W68_R0.7230.53
71_E76_K0.7230.53
39_W100_F0.7220.53
167_N219_V0.7180.52
27_D35_Q0.7170.52
28_F188_L0.7170.52
166_L213_M0.7110.52
146_L150_K0.7080.51
58_D137_S0.7030.51
103_E156_Y0.7010.51
115_A143_E0.7010.51
102_W156_Y0.7010.51
99_L104_D0.7010.51
179_K200_K0.7010.51
118_Y204_D0.6960.50
154_K216_F0.6960.50
166_L218_F0.6950.50
54_K57_S0.6950.50
186_V197_I0.6940.50
66_L148_F0.6910.50
179_K198_S0.6890.49
62_H128_F0.6860.49
212_E216_F0.6840.49
19_I22_I0.6830.49
168_F171_P0.6770.48
116_G148_F0.6760.48
45_T102_W0.6760.48
93_D109_V0.6740.48
124_K136_S0.6740.48
100_F105_V0.6700.48
104_D169_W0.6640.47
109_V113_D0.6570.46
29_E62_H0.6520.46
196_L204_D0.6490.45
148_F152_V0.6450.45
24_L185_E0.6440.45
125_D164_A0.6430.45
56_V60_L0.6420.45
118_Y201_L0.6400.44
207_R210_N0.6400.44
154_K215_N0.6380.44
128_F138_M0.6360.44
95_S176_M0.6360.44
66_L113_D0.6350.44
22_I130_P0.6270.43
165_A169_W0.6260.43
73_F191_L0.6230.43
164_A219_V0.6230.43
22_I69_L0.6220.43
59_E62_H0.6200.43
94_I213_M0.6200.43
20_E182_S0.6170.42
179_K182_S0.6160.42
148_F151_N0.6150.42
111_L173_A0.6130.42
167_N213_M0.6110.42
55_L131_L0.6090.41
61_N144_S0.6080.41
58_D144_S0.6060.41
102_W128_F0.6050.41
88_G181_K0.6050.41
21_I34_E0.6010.41
162_L165_A0.5990.40
57_S61_N0.5950.40
213_M220_E0.5940.40
117_L146_L0.5930.40
105_V134_L0.5880.39
18_L73_F0.5880.39
136_S139_I0.5870.39
177_L202_I0.5840.39
16_N203_E0.5840.39
29_E59_E0.5820.39
27_D84_E0.5780.38
43_A53_A0.5770.38
45_T148_F0.5760.38
36_I102_W0.5760.38
29_E116_G0.5750.38
156_Y162_L0.5720.38
43_A59_E0.5710.38
16_N20_E0.5690.38
36_I60_L0.5680.37
95_S99_L0.5650.37
173_A176_M0.5640.37
213_M217_G0.5630.37
168_F219_V0.5590.37
22_I26_A0.5580.37
125_D210_N0.5570.36
71_E74_N0.5570.36
51_F156_Y0.5560.36
33_V112_V0.5540.36
104_D165_A0.5510.36
198_S203_E0.5500.36
125_D214_R0.5490.36
212_E215_N0.5480.36
54_K141_E0.5470.35
137_S165_A0.5470.35
22_I131_L0.5450.35
36_I56_V0.5440.35
119_Q142_E0.5440.35
70_L128_F0.5430.35
28_F101_N0.5390.35
40_L65_Q0.5390.35
167_N181_K0.5360.34
103_E162_L0.5350.34
121_R125_D0.5340.34
211_D219_V0.5340.34
69_L109_V0.5330.34
188_L191_L0.5330.34
134_L137_S0.5330.34
190_D193_V0.5310.34
45_T48_D0.5310.34
61_N137_S0.5300.34
18_L69_L0.5300.34
92_L205_Y0.5300.34
191_L203_E0.5290.34
143_E146_L0.5280.34
99_L105_V0.5270.34
125_D186_V0.5260.34
33_V115_A0.5230.33
121_R193_V0.5200.33
31_G129_E0.5200.33
171_P198_S0.5130.32
137_S156_Y0.5130.32
118_Y205_Y0.5120.32
67_V170_F0.5120.32
148_F205_Y0.5090.32
43_A50_L0.5080.32
23_V70_L0.5060.32
54_K137_S0.5050.32
85_A200_K0.5050.32
37_S105_V0.5050.32
121_R204_D0.5040.32
87_L174_L0.5040.32
130_P138_M0.5030.32
189_R197_I0.5030.32
68_R220_E0.5020.31
160_N210_N0.5020.31
18_L62_H0.5010.31
114_R209_T0.5000.31
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1otkA 2 0.9145 100 0.181 Contact Map
3pf7A 1 0.9829 100 0.207 Contact Map
3pvtA 1 0.9872 100 0.217 Contact Map
4mudA 2 0.9359 100 0.231 Contact Map
3ge3A 2 0.9573 98.6 0.855 Contact Map
2incA 2 0.9615 98.5 0.859 Contact Map
1mtyD 2 0.9615 98.4 0.864 Contact Map
3ez0A 2 0.8846 98.3 0.867 Contact Map
1mtyB 2 0.9658 98.2 0.87 Contact Map
3u52A 2 0.9487 98 0.879 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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