Y2030 - SULSO - GREMLIN Contacts

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Y2030 - Putative ABC transporter ATP-binding protein SSO2030

UniProt:	Q97WT4	Sequences: MKFVEIRDLQVTYMGKDKPSIVVDKLDIEEGESVLITGRSGSGKSTLVSVINGVIPHLINAEIKGEVRVFGFDVKSTPIHEISKYVGTLLQDPDTQAFNYTIIDEVAFGVENYMISRDEMIERVEESMKIYGISHLRDREINTLSGGELQRTILASVLAMRPKALILDEPTSNIDPQGTREILELVKTFRSEGISLVLVEHKIERVLPFVDRIIVVEEGKIAVDVRKDEIVDKADFLYSLGLEIPDYMLFLKKNGFRKIDYEYLRKTYTYRPPSRIGGKGEALYASVKVKTKNGIYLINTKISLKQGTITALMGKNGSGKTTLLKVIVGLIDKKRLIVEEEKVIVNGVDLSKTKLVERGKFIAYLPQFFDVMFIKRTVEDEIKFSMKNRGTYDEKRLGEVLKMFSLDAYRKEDPLVLSMGQRRRVAMASVLAGGAKVILMDEPTSGQDWYHRQILGKELLELRDKGYTILVVTHDSRFVDRFADYLLVMNEGKIVLEGKPEEVFIKSLRHGIEPPLEYELGGLIKNEHFS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	530 (476)
Sequences:	1436 (1017)
Seq/√Len:	46.6

ECOLI - XYLG ALSA MGLA MODF YPHE YTFR YEJF LSRA GSIA UUP ARAG YHES RBSA YBHF ETTA
BACSU - YKPA YFMM YUFO YKOD RBSA YFMR EXPZ YDIF
HALSA - Q9HR21 Q9HMC1
SULSO - Y2030 Y1893 Q97UG5 Q980K5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
6_I	9_L	5.573	1.00
401_L	410_R	5.506	1.00
286_S	299_N	4.677	1.00
8_D	23_V	4.671	1.00
308_T	485_Y	4.255	1.00
128_M	137_R	4.218	1.00
7_R	66_E	4.143	1.00
79_I	82_I	3.859	1.00
361_F	436_K	3.816	1.00
11_V	46_T	3.689	1.00
498_G	502_E	3.662	1.00
32_E	212_R	3.536	1.00
379_E	411_K	3.410	1.00
284_Y	287_V	3.404	1.00
34_V	214_I	3.358	1.00
22_V	220_K	3.355	1.00
324_L	472_V	3.305	1.00
5_E	27_D	3.288	1.00
283_L	303_S	3.118	1.00
311_A	483_A	3.098	1.00
285_A	342_K	2.983	1.00
85_Y	163_K	2.977	1.00
298_I	493_K	2.907	1.00
9_L	50_V	2.876	1.00
473_T	479_V	2.838	1.00
212_R	224_D	2.815	1.00
214_I	221_I	2.775	1.00
8_D	25_K	2.699	1.00
403_M	461_E	2.682	1.00
5_E	68_R	2.449	1.00
51_I	197_V	2.429	1.00
146_G	367_Q	2.426	1.00
286_S	301_K	2.419	1.00
129_K	134_S	2.396	1.00
379_E	410_R	2.392	1.00
461_E	465_K	2.388	1.00
279_K	306_Q	2.354	1.00
48_V	199_V	2.323	1.00
402_K	407_D	2.270	1.00
106_V	128_M	2.250	1.00
283_L	344_I	2.233	1.00
106_V	137_R	2.145	1.00
280_G	305_K	2.083	1.00
29_E	32_E	2.077	1.00
62_E	67_V	2.072	1.00
26_L	214_I	2.046	0.99
289_V	326_V	2.001	0.99
226_R	229_E	1.996	0.99
6_I	26_L	1.986	0.99
66_E	73_D	1.982	0.99
207_L	231_V	1.980	0.99
4_V	69_V	1.971	0.99
247_Y	250_F	1.963	0.99
12_T	19_P	1.955	0.99
106_V	159_A	1.948	0.99
432_A	437_V	1.946	0.99
419_M	423_R	1.941	0.99
324_L	439_L	1.935	0.99
103_I	107_A	1.932	0.99
19_P	22_V	1.907	0.99
87_G	157_V	1.875	0.99
225_V	229_E	1.870	0.99
304_L	310_T	1.856	0.99
297_L	322_T	1.818	0.99
284_Y	327_I	1.814	0.99
28_I	34_V	1.796	0.99
370_D	373_F	1.792	0.99
186_V	196_L	1.777	0.99
9_L	67_V	1.771	0.99
280_G	306_Q	1.748	0.98
270_Y	273_P	1.736	0.98
126_E	188_T	1.699	0.98
392_Y	434_G	1.671	0.98
45_S	49_S	1.662	0.98
373_F	381_E	1.654	0.98
251_L	254_N	1.649	0.98
409_Y	412_E	1.648	0.98
284_Y	302_I	1.648	0.98
126_E	192_E	1.647	0.98
425_V	429_S	1.616	0.97
6_I	51_I	1.613	0.97
187_K	208_P	1.612	0.97
35_L	210_V	1.600	0.97
107_A	124_V	1.595	0.97
249_L	252_K	1.583	0.97
285_A	301_K	1.567	0.97
10_Q	23_V	1.549	0.96
151_R	178_G	1.548	0.96
217_E	254_N	1.545	0.96
398_G	410_R	1.534	0.96
454_I	457_K	1.532	0.96
372_M	381_E	1.504	0.96
320_K	474_H	1.500	0.96
379_E	383_K	1.492	0.96
308_T	484_D	1.491	0.96
286_S	340_E	1.489	0.96
246_D	250_F	1.484	0.95
285_A	344_I	1.481	0.95
78_P	81_E	1.479	0.95
66_E	75_K	1.479	0.95
320_K	441_D	1.477	0.95
116_S	119_E	1.450	0.95
101_T	104_D	1.449	0.95
241_G	246_D	1.447	0.95
179_T	202_K	1.446	0.95
10_Q	19_P	1.443	0.95
247_Y	254_N	1.441	0.95
242_L	246_D	1.440	0.95
6_I	67_V	1.439	0.95
23_V	220_K	1.435	0.95
386_M	393_D	1.433	0.95
316_N	320_K	1.433	0.95
378_V	381_E	1.433	0.95
247_Y	251_L	1.427	0.94
108_F	112_N	1.421	0.94
103_I	137_R	1.414	0.94
247_Y	252_K	1.404	0.94
45_S	92_D	1.399	0.94
320_K	442_E	1.394	0.94
280_G	283_L	1.391	0.94
304_L	470_L	1.390	0.94
48_V	166_I	1.380	0.93
121_I	125_E	1.373	0.93
243_E	246_D	1.367	0.93
163_K	194_I	1.352	0.93
30_E	163_K	1.346	0.92
397_L	400_V	1.341	0.92
175_D	320_K	1.340	0.92
77_T	81_E	1.339	0.92
241_G	244_I	1.331	0.92
175_D	474_H	1.330	0.92
52_N	166_I	1.330	0.92
33_S	186_V	1.330	0.92
252_K	255_G	1.315	0.92
243_E	250_F	1.307	0.91
305_K	308_T	1.303	0.91
246_D	254_N	1.299	0.91
105_E	156_S	1.297	0.91
316_N	474_H	1.294	0.91
248_M	252_K	1.287	0.91
119_E	123_R	1.277	0.90
147_G	320_K	1.277	0.90
290_K	295_I	1.273	0.90
441_D	474_H	1.267	0.90
242_L	249_L	1.266	0.90
252_K	256_F	1.264	0.90
49_S	54_V	1.263	0.90
269_T	272_P	1.262	0.90
357_E	360_K	1.258	0.90
246_D	252_K	1.256	0.90
399_E	403_M	1.254	0.90
35_L	213_I	1.254	0.90
200_E	206_V	1.250	0.89
397_L	432_A	1.249	0.89
392_Y	395_K	1.245	0.89
280_G	303_S	1.233	0.89
187_K	191_S	1.232	0.89
281_E	305_K	1.231	0.89
311_A	479_V	1.226	0.88
96_Q	112_N	1.221	0.88
246_D	253_K	1.221	0.88
145_S	474_H	1.209	0.88
307_G	466_G	1.207	0.88
245_P	250_F	1.202	0.87
45_S	199_V	1.195	0.87
310_T	470_L	1.194	0.87
247_Y	253_K	1.188	0.87
246_D	251_L	1.171	0.86
366_P	372_M	1.171	0.86
103_I	138_D	1.171	0.86
147_G	474_H	1.159	0.85
243_E	251_L	1.155	0.85
246_D	249_L	1.142	0.85
195_S	212_R	1.135	0.84
309_I	459_L	1.129	0.84
4_V	197_V	1.129	0.84
268_Y	273_P	1.128	0.84
328_V	439_L	1.126	0.84
254_N	258_K	1.126	0.84
248_M	253_K	1.126	0.84
228_D	232_D	1.120	0.83
327_I	425_V	1.118	0.83
250_F	254_N	1.116	0.83
201_H	418_S	1.114	0.83
456_G	478_F	1.108	0.83
473_T	478_F	1.106	0.83
376_R	381_E	1.100	0.82
119_E	122_E	1.098	0.82
447_Q	455_L	1.090	0.82
201_H	475_D	1.088	0.82
454_I	458_E	1.084	0.81
125_E	129_K	1.079	0.81
40_S	424_R	1.078	0.81
316_N	441_D	1.078	0.81
326_V	333_K	1.075	0.81
462_L	467_Y	1.075	0.81
239_S	242_L	1.075	0.81
47_L	216_V	1.074	0.81
21_I	47_L	1.066	0.80
147_G	317_G	1.058	0.80
147_G	316_N	1.056	0.80
253_K	258_K	1.052	0.79
70_F	163_K	1.050	0.79
103_I	121_I	1.044	0.79
4_V	195_S	1.039	0.78
298_I	491_E	1.037	0.78
33_S	195_S	1.032	0.78
485_Y	497_E	1.031	0.78
321_T	441_D	1.023	0.77
397_L	410_R	1.015	0.77
299_N	340_E	1.010	0.76
300_T	494_I	1.007	0.76
249_L	253_K	1.005	0.76
239_S	243_E	1.002	0.76
400_V	431_L	0.991	0.75
306_Q	468_T	0.989	0.75
356_V	360_K	0.988	0.75
36_I	42_S	0.988	0.75
27_D	348_V	0.987	0.75
442_E	474_H	0.984	0.75
21_I	216_V	0.984	0.75
154_L	167_L	0.982	0.74
412_E	416_V	0.980	0.74
322_T	474_H	0.979	0.74
109_G	160_M	0.978	0.74
225_V	230_I	0.975	0.74
135_H	148_E	0.975	0.74
304_L	327_I	0.972	0.74
300_T	489_M	0.971	0.74
110_V	120_M	0.969	0.73
223_V	230_I	0.969	0.73
242_L	245_P	0.967	0.73
267_T	270_Y	0.966	0.73
456_G	482_F	0.962	0.73
251_L	255_G	0.958	0.73
297_L	326_V	0.958	0.73
460_L	463_R	0.956	0.72
72_F	84_K	0.956	0.72
171_T	205_R	0.952	0.72
34_V	212_R	0.950	0.72
126_E	129_K	0.949	0.72
310_T	487_L	0.943	0.71
130_I	188_T	0.942	0.71
241_G	249_L	0.937	0.71
406_L	424_R	0.934	0.71
42_S	327_I	0.929	0.70
342_K	349_D	0.927	0.70
164_A	195_S	0.927	0.70
248_M	251_L	0.921	0.70
287_V	326_V	0.920	0.69
239_S	246_D	0.918	0.69
245_P	248_M	0.917	0.69
399_E	434_G	0.916	0.69
125_E	134_S	0.915	0.69
249_L	254_N	0.915	0.69
241_G	245_P	0.912	0.69
109_G	159_A	0.912	0.69
250_F	253_K	0.905	0.68
243_E	249_L	0.901	0.68
365_L	427_M	0.897	0.67
344_I	349_D	0.897	0.67
455_L	459_L	0.895	0.67
325_K	331_I	0.892	0.67
413_D	416_V	0.891	0.67
459_L	463_R	0.891	0.67
313_M	479_V	0.891	0.67
167_L	446_G	0.886	0.67
316_N	442_E	0.885	0.66
445_S	452_R	0.882	0.66
148_E	206_V	0.881	0.66
103_I	106_V	0.880	0.66
436_K	467_Y	0.873	0.65
90_L	96_Q	0.873	0.65
239_S	245_P	0.872	0.65
40_S	112_N	0.869	0.65
81_E	398_G	0.866	0.65
175_D	441_D	0.862	0.64
300_T	427_M	0.862	0.64
401_L	437_V	0.862	0.64
190_R	196_L	0.861	0.64
244_I	247_Y	0.861	0.64
285_A	402_K	0.859	0.64
158_L	165_L	0.849	0.63
247_Y	256_F	0.846	0.63
24_D	66_E	0.846	0.63
254_N	257_R	0.845	0.63
72_F	77_T	0.842	0.63
136_L	139_R	0.840	0.62
380_D	489_M	0.839	0.62
278_G	306_Q	0.836	0.62
175_D	316_N	0.835	0.62
238_Y	242_L	0.834	0.62
33_S	196_L	0.833	0.62
189_F	440_M	0.832	0.62
243_E	247_Y	0.828	0.61
239_S	247_Y	0.826	0.61
279_K	391_T	0.825	0.61
367_Q	474_H	0.821	0.61
103_I	110_V	0.821	0.61
40_S	414_P	0.821	0.61
479_V	486_L	0.818	0.60
147_G	175_D	0.814	0.60
131_Y	152_T	0.812	0.60
6_I	164_A	0.812	0.60
117_R	121_I	0.809	0.59
459_L	469_I	0.809	0.59
499_K	502_E	0.808	0.59
460_L	464_D	0.808	0.59
245_P	251_L	0.807	0.59
7_R	27_D	0.806	0.59
382_I	429_S	0.805	0.59
105_E	381_E	0.804	0.59
377_T	381_E	0.801	0.59
13_Y	108_F	0.799	0.58
288_K	295_I	0.794	0.58
306_Q	466_G	0.794	0.58
107_A	128_M	0.792	0.58
459_L	480_D	0.791	0.58
108_F	160_M	0.790	0.58
27_D	192_E	0.786	0.57
285_A	303_S	0.786	0.57
404_F	428_A	0.786	0.57
239_S	244_I	0.785	0.57
161_R	194_I	0.785	0.57
431_L	458_E	0.785	0.57
325_K	330_L	0.780	0.57
106_V	187_K	0.780	0.57
418_S	421_Q	0.775	0.56
18_K	64_K	0.775	0.56
245_P	252_K	0.774	0.56
173_N	445_S	0.773	0.56
316_N	322_T	0.772	0.56
201_H	419_M	0.772	0.56
394_E	465_K	0.771	0.56
214_I	224_D	0.769	0.56
297_L	489_M	0.768	0.55
362_I	437_V	0.767	0.55
102_I	484_D	0.767	0.55
47_L	102_I	0.765	0.55
204_E	480_D	0.760	0.55
28_I	51_I	0.759	0.55
35_L	365_L	0.758	0.54
396_R	399_E	0.755	0.54
253_K	256_F	0.754	0.54
268_Y	272_P	0.752	0.54
382_I	397_L	0.750	0.54
313_M	476_S	0.749	0.54
145_S	148_E	0.748	0.53
366_P	371_V	0.748	0.53
349_D	352_K	0.746	0.53
487_L	494_I	0.746	0.53
111_E	120_M	0.746	0.53
201_H	447_Q	0.746	0.53
270_Y	276_I	0.745	0.53
291_T	439_L	0.744	0.53
41_G	44_K	0.744	0.53
250_F	255_G	0.742	0.53
414_P	425_V	0.742	0.53
12_T	22_V	0.740	0.53
100_Y	105_E	0.740	0.53
444_T	473_T	0.738	0.52
98_F	173_N	0.738	0.52
123_R	126_E	0.738	0.52
188_T	405_S	0.737	0.52
45_S	87_G	0.735	0.52
145_S	320_K	0.733	0.52
291_T	326_V	0.733	0.52
241_G	247_Y	0.731	0.52
244_I	249_L	0.729	0.52
13_Y	55_I	0.728	0.52
93_P	97_A	0.728	0.52
182_I	487_L	0.727	0.51
453_Q	481_R	0.725	0.51
406_L	425_V	0.725	0.51
323_L	489_M	0.723	0.51
272_P	275_R	0.722	0.51
497_E	502_E	0.722	0.51
371_V	381_E	0.722	0.51
200_E	373_F	0.722	0.51
46_T	49_S	0.721	0.51
145_S	316_N	0.720	0.51
7_R	25_K	0.720	0.51
140_E	143_T	0.718	0.51
115_I	122_E	0.715	0.50
38_G	43_G	0.713	0.50
4_V	28_I	0.713	0.50
291_T	298_I	0.712	0.50
107_A	121_I	0.710	0.50
7_R	68_R	0.709	0.50
145_S	175_D	0.709	0.50
96_Q	108_F	0.707	0.49
203_I	210_V	0.707	0.49
374_I	381_E	0.706	0.49
40_S	88_T	0.706	0.49
36_I	216_V	0.705	0.49
224_D	229_E	0.705	0.49
72_F	81_E	0.704	0.49
158_L	176_P	0.703	0.49
383_K	397_L	0.702	0.49
73_D	76_S	0.702	0.49
155_A	159_A	0.702	0.49
244_I	251_L	0.700	0.49
125_E	137_R	0.700	0.49
92_D	172_S	0.700	0.49
134_S	137_R	0.700	0.49
129_K	220_K	0.699	0.49
146_G	474_H	0.699	0.49
198_L	424_R	0.697	0.48
321_T	460_L	0.696	0.48
4_V	164_A	0.696	0.48
38_G	44_K	0.694	0.48
98_F	452_R	0.694	0.48
216_V	343_V	0.694	0.48
46_T	497_E	0.693	0.48
118_D	122_E	0.693	0.48
32_E	211_D	0.690	0.48
271_R	274_S	0.690	0.48
462_L	469_I	0.689	0.48
11_V	50_V	0.689	0.48
111_E	414_P	0.689	0.48
175_D	444_T	0.688	0.48
90_L	112_N	0.688	0.48
45_S	93_P	0.687	0.47
138_D	412_E	0.687	0.47
78_P	212_R	0.687	0.47
316_N	440_M	0.686	0.47
317_G	441_D	0.686	0.47
175_D	321_T	0.685	0.47
184_E	191_S	0.685	0.47
10_Q	25_K	0.684	0.47
89_L	199_V	0.681	0.47
348_V	352_K	0.680	0.47
98_F	472_V	0.679	0.47
221_I	303_S	0.678	0.47
231_V	234_A	0.676	0.46
13_Y	46_T	0.676	0.46
401_L	421_Q	0.675	0.46
51_I	333_K	0.674	0.46
174_I	418_S	0.673	0.46
116_S	499_K	0.673	0.46
213_I	425_V	0.673	0.46
220_K	486_L	0.673	0.46
452_R	478_F	0.672	0.46
253_K	257_R	0.671	0.46
173_N	452_R	0.670	0.46
21_I	24_D	0.667	0.45
404_F	431_L	0.667	0.45
145_S	441_D	0.666	0.45
174_I	202_K	0.665	0.45
423_R	445_S	0.665	0.45
150_Q	172_S	0.664	0.45
289_V	334_K	0.663	0.45
232_D	285_A	0.663	0.45
243_E	252_K	0.663	0.45
317_G	320_K	0.662	0.45
227_K	230_I	0.662	0.45
487_L	497_E	0.661	0.45
38_G	41_G	0.660	0.45
150_Q	423_R	0.660	0.45
166_I	200_E	0.660	0.45
231_V	401_L	0.656	0.44
321_T	474_H	0.656	0.44
400_V	432_A	0.651	0.44
95_T	216_V	0.651	0.44
91_Q	446_G	0.651	0.44
110_V	159_A	0.650	0.44
89_L	93_P	0.650	0.44
10_Q	374_I	0.649	0.44
288_K	298_I	0.649	0.44
216_V	221_I	0.648	0.44
146_G	442_E	0.645	0.43
153_I	214_I	0.645	0.43
422_R	445_S	0.645	0.43
375_K	381_E	0.643	0.43
316_N	367_Q	0.642	0.43
269_T	273_P	0.642	0.43
243_E	248_M	0.639	0.43
270_Y	397_L	0.638	0.43
205_R	478_F	0.638	0.43
164_A	340_E	0.638	0.43
242_L	247_Y	0.637	0.43
133_I	438_I	0.637	0.43
267_T	273_P	0.636	0.42
404_F	458_E	0.636	0.42
344_I	396_R	0.634	0.42
409_Y	414_P	0.633	0.42
424_R	445_S	0.633	0.42
331_I	481_R	0.632	0.42
201_H	421_Q	0.631	0.42
31_G	193_G	0.630	0.42
247_Y	255_G	0.630	0.42
297_L	300_T	0.629	0.42
306_Q	436_K	0.629	0.42
11_V	49_S	0.628	0.42
161_R	286_S	0.626	0.41
116_S	399_E	0.626	0.41
268_Y	276_I	0.625	0.41
40_S	96_Q	0.625	0.41
121_I	305_K	0.624	0.41
379_E	397_L	0.624	0.41
150_Q	171_T	0.621	0.41
401_L	414_P	0.621	0.41
173_N	202_K	0.621	0.41
169_E	418_S	0.621	0.41
198_L	464_D	0.621	0.41
40_S	447_Q	0.621	0.41
152_T	480_D	0.620	0.41
242_L	250_F	0.619	0.41
36_I	123_R	0.618	0.41
478_F	482_F	0.618	0.41
376_R	380_D	0.618	0.41
240_L	245_P	0.617	0.41
97_A	141_I	0.617	0.41
93_P	111_E	0.616	0.41
98_F	179_T	0.614	0.40
241_G	248_M	0.612	0.40
67_V	411_K	0.611	0.40
163_K	240_L	0.610	0.40
351_S	354_K	0.609	0.40
32_E	195_S	0.609	0.40
226_R	391_T	0.608	0.40
95_T	130_I	0.607	0.40
151_R	181_E	0.607	0.40
105_E	141_I	0.606	0.40
340_E	498_G	0.606	0.40
281_E	346_N	0.606	0.40
352_K	400_V	0.606	0.40
193_G	493_K	0.604	0.39
91_Q	444_T	0.604	0.39
25_K	118_D	0.603	0.39
6_I	208_P	0.602	0.39
117_R	501_E	0.602	0.39
249_L	258_K	0.601	0.39
93_P	414_P	0.601	0.39
182_I	488_V	0.601	0.39
139_R	143_T	0.601	0.39
8_D	12_T	0.600	0.39
70_F	274_S	0.599	0.39
150_Q	446_G	0.599	0.39
27_D	229_E	0.598	0.39
288_K	340_E	0.596	0.39
133_I	136_L	0.596	0.39
202_K	452_R	0.595	0.39
136_L	148_E	0.595	0.39
151_R	452_R	0.595	0.39
25_K	276_I	0.595	0.39
288_K	299_N	0.594	0.38
363_A	435_A	0.594	0.38
309_I	423_R	0.593	0.38
282_A	304_L	0.593	0.38
148_E	152_T	0.593	0.38
286_S	457_K	0.593	0.38
26_L	126_E	0.592	0.38
342_K	400_V	0.591	0.38
223_V	233_K	0.591	0.38
379_E	398_G	0.589	0.38
222_A	290_K	0.589	0.38
207_L	496_L	0.588	0.38
312_L	386_M	0.588	0.38
403_M	458_E	0.587	0.38
396_R	434_G	0.586	0.38
11_V	63_I	0.585	0.38
98_F	148_E	0.585	0.38
116_S	272_P	0.585	0.38
31_G	106_V	0.584	0.38
193_G	232_D	0.584	0.38
5_E	8_D	0.584	0.38
51_I	66_E	0.584	0.38
235_D	238_Y	0.582	0.37
84_K	213_I	0.582	0.37
154_L	176_P	0.582	0.37
182_I	312_L	0.581	0.37
148_E	183_L	0.581	0.37
170_P	443_P	0.579	0.37
90_L	98_F	0.579	0.37
435_A	440_M	0.578	0.37
105_E	108_F	0.574	0.37
89_L	94_D	0.574	0.37
89_L	154_L	0.573	0.37
419_M	424_R	0.572	0.36
277_G	305_K	0.572	0.36
257_R	268_Y	0.572	0.36
64_K	398_G	0.571	0.36
45_S	55_I	0.571	0.36
312_L	470_L	0.570	0.36
239_S	251_L	0.570	0.36
400_V	428_A	0.569	0.36
15_G	274_S	0.569	0.36
90_L	105_E	0.567	0.36
303_S	399_E	0.567	0.36
245_P	249_L	0.566	0.36
101_T	300_T	0.566	0.36
197_V	231_V	0.565	0.36
86_V	285_A	0.564	0.36
127_S	196_L	0.564	0.36
159_A	432_A	0.564	0.36
423_R	447_Q	0.564	0.36
178_G	372_M	0.562	0.36
147_G	441_D	0.561	0.35
197_V	226_R	0.560	0.35
179_T	204_E	0.560	0.35
6_I	50_V	0.560	0.35
373_F	384_F	0.560	0.35
93_P	109_G	0.559	0.35
330_L	422_R	0.559	0.35
165_L	194_I	0.559	0.35
173_N	206_V	0.558	0.35
224_D	227_K	0.558	0.35
106_V	155_A	0.556	0.35
279_K	501_E	0.556	0.35
273_P	278_G	0.556	0.35
192_E	340_E	0.552	0.35
322_T	441_D	0.552	0.35
234_A	237_L	0.551	0.35
89_L	201_H	0.550	0.34
256_F	275_R	0.550	0.34
284_Y	453_Q	0.546	0.34
19_P	405_S	0.546	0.34
192_E	197_V	0.546	0.34
269_T	274_S	0.546	0.34
206_V	423_R	0.545	0.34
255_G	258_K	0.544	0.34
200_E	478_F	0.544	0.34
130_I	185_L	0.544	0.34
22_V	494_I	0.544	0.34
81_E	197_V	0.542	0.34
245_P	253_K	0.542	0.34
309_I	439_L	0.542	0.34
27_D	276_I	0.541	0.34
14_M	20_S	0.541	0.34
11_V	213_I	0.540	0.34
248_M	254_N	0.539	0.33
172_S	426_A	0.539	0.33
204_E	207_L	0.539	0.33
332_D	357_E	0.538	0.33
146_G	424_R	0.538	0.33
405_S	408_A	0.538	0.33
27_D	436_K	0.537	0.33
328_V	364_Y	0.537	0.33
145_S	442_E	0.536	0.33
70_F	122_E	0.536	0.33
358_R	400_V	0.534	0.33
310_T	469_I	0.534	0.33
23_V	228_D	0.533	0.33
381_E	384_F	0.533	0.33
258_K	268_Y	0.533	0.33
273_P	344_I	0.532	0.33
210_V	459_L	0.532	0.33
102_I	391_T	0.531	0.33
146_G	320_K	0.531	0.33
496_L	499_K	0.531	0.33
171_T	182_I	0.531	0.33
39_R	217_E	0.530	0.33
400_V	403_M	0.530	0.33
320_K	367_Q	0.530	0.33
150_Q	444_T	0.529	0.33
255_G	278_G	0.529	0.33
322_T	326_V	0.528	0.32
90_L	99_N	0.528	0.32
83_S	153_I	0.528	0.32
191_S	228_D	0.525	0.32
40_S	381_E	0.525	0.32
243_E	254_N	0.525	0.32
53_G	424_R	0.524	0.32
179_T	452_R	0.524	0.32
21_I	50_V	0.523	0.32
94_D	154_L	0.523	0.32
131_Y	136_L	0.523	0.32
122_E	126_E	0.522	0.32
398_G	407_D	0.522	0.32
99_N	105_E	0.522	0.32
23_V	461_E	0.522	0.32
92_D	108_F	0.522	0.32
172_S	201_H	0.522	0.32
229_E	342_K	0.520	0.32
450_Y	454_I	0.520	0.32
48_V	480_D	0.520	0.32
312_L	473_T	0.519	0.32
213_I	362_I	0.519	0.32
132_G	193_G	0.518	0.32
63_I	105_E	0.516	0.31
202_K	205_R	0.516	0.31
301_K	344_I	0.516	0.31
79_I	83_S	0.516	0.31
183_L	206_V	0.515	0.31
334_K	436_K	0.515	0.31
71_G	275_R	0.515	0.31
5_E	29_E	0.514	0.31
290_K	379_E	0.513	0.31
101_T	111_E	0.512	0.31
98_F	105_E	0.510	0.31
49_S	55_I	0.510	0.31
90_L	94_D	0.510	0.31
6_I	15_G	0.509	0.31
149_L	426_A	0.508	0.31
240_L	246_D	0.508	0.31
268_Y	271_R	0.506	0.31
244_I	254_N	0.505	0.31
169_E	201_H	0.505	0.31
116_S	121_I	0.504	0.30
175_D	367_Q	0.504	0.30
184_E	408_A	0.504	0.30
487_L	490_N	0.504	0.30
371_V	374_I	0.504	0.30
247_Y	258_K	0.503	0.30
105_E	202_K	0.503	0.30
230_I	233_K	0.503	0.30
188_T	192_E	0.502	0.30
378_V	425_V	0.502	0.30
12_T	122_E	0.502	0.30
296_Y	322_T	0.501	0.30
460_L	484_D	0.501	0.30
154_L	162_P	0.500	0.30
427_M	447_Q	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4q9hA	1	0.9226	100	0.299	Contact Map
4f4cA	1	0.9038	100	0.314	Contact Map
4finA	2	0.8981	100	0.326	Contact Map
1yqtA	1	0.9057	100	0.353	Contact Map
3ozxA	1	0.8887	100	0.356	Contact Map
3bk7A	1	0.917	100	0.357	Contact Map
2iw3A	2	0.8245	100	0.363	Contact Map
3j16B	1	0.9075	100	0.371	Contact Map
3ux8A	2	0.8245	100	0.382	Contact Map
2vf7A	2	0.9208	100	0.455	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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