GREMLIN Database
Q97WQ2 - Indolepyruvate oxidoreductase subunit IorA
UniProt: Q97WQ2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 612 (578)
Sequences: 2809 (1712)
Seq/√Len: 71.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
232_E280_K4.5681.00
140_Q144_D4.1871.00
519_P522_V3.2471.00
358_P565_A3.1171.00
21_A78_T3.0321.00
268_P271_L3.0311.00
481_E484_K3.0011.00
104_V149_A2.8321.00
475_K478_D2.7801.00
327_Y331_S2.7301.00
504_R508_N2.6751.00
283_L333_F2.6691.00
464_T468_G2.6541.00
480_G484_K2.4841.00
547_D550_K2.4331.00
300_L309_L2.3971.00
545_I599_K2.3931.00
155_K208_E2.3511.00
434_S438_H2.3281.00
245_V285_V2.2631.00
547_D597_S2.2481.00
475_K480_G2.2481.00
467_T470_Q2.2381.00
207_V211_K2.2321.00
459_L463_S2.2291.00
467_T474_S2.2201.00
567_I577_D2.2061.00
138_D243_G2.2041.00
212_R215_R2.1971.00
101_G153_S2.1941.00
480_G483_A2.1741.00
136_P162_F2.1391.00
470_Q474_S2.1271.00
281_R308_E2.1111.00
269_K299_L2.1101.00
214_E220_V2.0921.00
477_I480_G2.0901.00
221_E224_N2.0881.00
464_T467_T2.0531.00
146_T162_F2.0391.00
476_E480_G2.0331.00
233_N281_R2.0241.00
480_G485_G2.0241.00
439_S442_S2.0201.00
478_D482_V1.9951.00
156_V202_A1.9701.00
478_D481_E1.9641.00
468_G474_S1.9621.00
458_V463_S1.9451.00
107_S122_N1.9411.00
91_L131_I1.9401.00
521_V524_A1.9111.00
84_L107_S1.9071.00
233_N254_I1.8991.00
147_I183_P1.8961.00
25_G150_F1.8941.00
254_I334_F1.8881.00
458_V462_R1.8701.00
463_S468_G1.8671.00
475_K482_V1.8651.00
226_L250_K1.8601.00
478_D488_V1.8571.00
65_A75_A1.8461.00
84_L105_I1.8421.00
479_I485_G1.8241.00
475_K479_I1.8231.00
23_S180_P1.8071.00
237_A245_V1.7911.00
234_L275_A1.7831.00
552_T593_F1.7801.00
294_Y298_D1.7771.00
519_P523_I1.7751.00
475_K483_A1.7691.00
463_S467_T1.7671.00
459_L462_R1.7591.00
479_I482_V1.7501.00
270_R274_K1.7441.00
465_A468_G1.7421.00
468_G473_P1.7391.00
483_A521_V1.7361.00
479_I483_A1.7271.00
91_L161_I1.7231.00
595_A598_L1.7161.00
223_L268_P1.6891.00
141_S260_R1.6821.00
233_N334_F1.6811.00
479_I487_G1.6801.00
68_A75_A1.6751.00
459_L467_T1.6711.00
31_G78_T1.6711.00
234_L276_V1.6691.00
466_M470_Q1.6671.00
519_P524_A1.6611.00
475_K489_K1.6591.00
109_D317_R1.6561.00
481_E485_G1.6551.00
126_G133_V1.6430.99
259_L271_L1.6430.99
543_K578_N1.6300.99
467_T473_P1.6210.99
478_D486_L1.6140.99
110_D121_D1.6070.99
458_V467_T1.6050.99
480_G487_G1.5950.99
568_P571_D1.5910.99
246_I260_R1.5900.99
478_D484_K1.5860.99
155_K186_G1.5850.99
62_F103_L1.5770.99
477_I482_V1.5710.99
211_K215_R1.5670.99
302_D306_R1.5660.99
482_V488_V1.5640.99
281_R310_H1.5620.99
315_V329_A1.5550.99
235_I245_V1.5540.99
464_T470_Q1.5500.99
214_E217_E1.5440.99
464_T474_S1.5310.99
480_G495_D1.5250.99
413_I456_V1.5190.99
462_R466_M1.5180.99
237_A241_S1.5140.99
441_I445_A1.5100.99
480_G489_K1.5070.99
220_V263_T1.4950.99
476_E485_G1.4940.99
137_Y242_F1.4860.99
479_I484_K1.4840.99
478_D487_G1.4800.99
222_G271_L1.4740.99
462_R465_A1.4720.99
164_S169_G1.4700.99
75_A103_L1.4690.99
483_A487_G1.4680.99
502_S511_K1.4660.99
460_D463_S1.4610.99
322_T325_K1.4610.99
479_I486_L1.4610.99
459_L468_G1.4440.99
468_G472_S1.4430.99
234_L279_S1.4410.99
390_G447_A1.4410.99
460_D464_T1.4380.99
196_V199_P1.4320.99
463_S474_S1.4310.99
92_I128_H1.4310.99
19_F23_S1.4280.99
488_V491_V1.4270.99
477_I487_G1.4260.99
475_K486_L1.4260.99
565_A580_T1.4200.98
17_I142_A1.4200.98
540_N582_I1.4190.98
466_M474_S1.4170.98
148_E223_L1.4150.98
237_A258_I1.4100.98
469_Q473_P1.4090.98
28_V64_T1.4090.98
236_I272_I1.4090.98
484_K488_V1.4070.98
479_I488_V1.4060.98
204_R270_R1.4050.98
276_V282_V1.4040.98
475_K488_V1.3970.98
126_G161_I1.3900.98
478_D489_K1.3890.98
17_I164_S1.3820.98
21_A76_L1.3820.98
15_E43_T1.3810.98
131_I161_I1.3810.98
479_I491_V1.3780.98
470_Q473_P1.3760.98
482_V485_G1.3760.98
467_T471_P1.3730.98
466_M469_Q1.3710.98
124_Y289_E1.3700.98
480_G486_L1.3670.98
477_I485_G1.3630.98
8_K176_E1.3630.98
485_G489_K1.3620.98
448_V488_V1.3500.98
460_D467_T1.3480.98
477_I484_K1.3430.98
483_A488_V1.3400.98
462_R467_T1.3380.98
88_A126_G1.3370.98
478_D483_A1.3310.98
495_D526_R1.3290.98
480_G488_V1.3270.98
399_P402_A1.3240.98
30_A64_T1.3210.98
476_E479_I1.3200.98
475_K484_K1.3190.98
235_I326_V1.3180.98
586_A589_P1.3130.97
297_K301_Y1.3110.97
304_G307_V1.2970.97
462_R468_G1.2920.97
484_K489_K1.2870.97
482_V486_L1.2830.97
458_V466_M1.2830.97
484_K487_G1.2790.97
482_V487_G1.2790.97
276_V300_L1.2770.97
281_R333_F1.2760.97
492_R512_W1.2740.97
148_E219_E1.2720.97
237_A242_F1.2700.97
205_D208_E1.2680.97
465_A469_Q1.2640.97
468_G471_P1.2630.97
463_S470_Q1.2630.97
593_F597_S1.2630.97
485_G488_V1.2620.97
483_A486_L1.2580.97
74_F154_N1.2520.97
459_L464_T1.2510.97
104_V146_T1.2510.97
480_G491_V1.2490.97
484_K491_V1.2460.96
476_E484_K1.2340.96
477_I489_K1.2300.96
156_V219_E1.2290.96
145_L262_T1.2280.96
281_R336_L1.2270.96
431_I434_S1.2250.96
486_L489_K1.2230.96
127_L294_Y1.2230.96
241_S321_M1.2200.96
478_D485_G1.2180.96
283_L310_H1.2150.96
477_I483_A1.2140.96
458_V464_T1.2100.96
550_K595_A1.2070.96
455_L460_D1.2070.96
476_E483_A1.2070.96
485_G490_Y1.2010.96
475_K481_E1.1980.96
466_M473_P1.1970.96
261_L264_P1.1960.96
464_T473_P1.1940.96
478_D491_V1.1940.96
487_G491_V1.1900.95
19_F143_H1.1880.95
476_E482_V1.1790.95
477_I481_E1.1750.95
531_L534_D1.1720.95
475_K487_G1.1660.95
259_L275_A1.1660.95
469_Q472_S1.1610.95
397_L466_M1.1600.95
310_H333_F1.1570.95
9_R15_E1.1540.95
122_N161_I1.1540.95
245_V258_I1.1540.95
198_V524_A1.1500.94
245_V248_A1.1490.94
249_I256_A1.1480.94
417_N446_N1.1440.94
390_G467_T1.1430.94
242_F260_R1.1360.94
463_S466_M1.1360.94
507_S511_K1.1340.94
187_K191_N1.1320.94
70_I527_A1.1290.94
462_R474_S1.1280.94
358_P361_P1.1260.94
88_A128_H1.1250.94
498_D505_E1.1240.94
332_K335_G1.1220.94
471_P474_S1.1200.94
465_A472_S1.1160.94
445_A449_Y1.1160.94
209_Q212_R1.1160.94
127_L291_I1.1150.94
544_A588_V1.1060.93
104_V150_F1.1050.93
156_V205_D1.1040.93
207_V271_L1.1030.93
271_L274_K1.1000.93
285_V329_A1.0980.93
245_V326_V1.0880.93
477_I486_L1.0880.93
197_L201_N1.0770.92
465_A473_P1.0700.92
206_R210_L1.0680.92
310_H313_D1.0670.92
484_K490_Y1.0650.92
132_P158_H1.0620.92
511_K515_D1.0620.92
431_I440_G1.0610.92
457_L460_D1.0590.92
458_V461_N1.0580.92
513_V522_V1.0580.92
465_A474_S1.0560.92
482_V491_V1.0560.92
267_I299_L1.0540.91
214_E224_N1.0510.91
327_Y361_P1.0500.91
134_V149_A1.0490.91
505_E508_N1.0480.91
545_I597_S1.0440.91
300_L307_V1.0440.91
134_V152_L1.0360.91
475_K485_G1.0300.91
504_R589_P1.0300.91
432_G436_F1.0260.90
459_L470_Q1.0190.90
457_L462_R1.0190.90
233_N283_L1.0130.90
40_I106_V1.0090.90
257_N279_S1.0060.89
321_M326_V1.0040.89
553_G573_K0.9990.89
259_L272_I0.9990.89
9_R177_L0.9970.89
469_Q474_S0.9960.89
214_E219_E0.9960.89
459_L466_M0.9960.89
457_L463_S0.9950.89
297_K309_L0.9940.89
44_L50_I0.9940.89
241_S326_V0.9930.89
506_L510_L0.9930.89
464_T472_S0.9920.89
207_V222_G0.9910.89
458_V523_I0.9900.89
505_E509_A0.9880.89
20_G183_P0.9860.88
247_D251_E0.9860.88
393_T406_S0.9840.88
462_R470_Q0.9800.88
465_A470_Q0.9740.88
218_E270_R0.9730.88
39_E43_T0.9720.88
508_N512_W0.9710.88
476_E488_V0.9710.88
21_A29_A0.9690.88
476_E487_G0.9660.87
211_K214_E0.9650.87
567_I582_I0.9650.87
441_I486_L0.9620.87
143_H177_L0.9620.87
458_V470_Q0.9610.87
102_A154_N0.9600.87
458_V483_A0.9550.87
63_E90_P0.9550.87
21_A40_I0.9510.87
595_A599_K0.9500.87
391_C403_Q0.9490.87
448_V519_P0.9480.86
458_V474_S0.9460.86
596_I600_G0.9440.86
458_V521_V0.9410.86
458_V468_G0.9390.86
475_K491_V0.9350.86
481_E488_V0.9350.86
23_S143_H0.9340.86
225_E228_D0.9330.86
539_S579_Y0.9320.86
222_G275_A0.9320.86
459_L465_A0.9320.86
223_L261_L0.9310.85
414_G443_A0.9300.85
493_Y525_K0.9300.85
220_V224_N0.9290.85
553_G572_K0.9290.85
231_S257_N0.9270.85
147_I178_K0.9250.85
134_V162_F0.9240.85
98_G198_V0.9230.85
142_A162_F0.9210.85
274_K277_S0.9180.85
109_D121_D0.9180.85
362_H433_D0.9170.85
463_S471_P0.9170.85
487_G490_Y0.9150.84
516_N520_A0.9130.84
593_F596_I0.9120.84
460_D466_M0.9120.84
140_Q143_H0.9110.84
276_V299_L0.9100.84
43_T46_K0.9090.84
224_N227_I0.9070.84
467_T472_S0.9070.84
272_I296_V0.9050.84
115_S317_R0.9030.84
485_G491_V0.9020.84
267_I272_I0.9010.84
30_A55_S0.9010.84
302_D340_T0.8990.83
200_E351_P0.8980.83
476_E481_E0.8960.83
208_E212_R0.8950.83
236_I296_V0.8950.83
552_T556_I0.8940.83
273_L303_Q0.8940.83
389_I467_T0.8930.83
340_T353_P0.8910.83
179_P182_R0.8900.83
301_Y307_V0.8890.83
453_P518_Q0.8870.83
567_I576_I0.8850.82
125_Y128_H0.8850.82
459_L474_S0.8850.82
228_D257_N0.8830.82
461_N467_T0.8780.82
505_E528_C0.8750.82
455_L520_A0.8750.82
113_M194_R0.8730.82
292_V296_V0.8700.81
92_I125_Y0.8700.81
189_I192_P0.8660.81
62_F77_T0.8650.81
230_D255_K0.8640.81
357_C360_C0.8630.81
249_I330_F0.8620.81
135_E163_R0.8620.81
249_I258_I0.8610.81
302_D341_D0.8610.81
503_I506_L0.8600.81
113_M195_Y0.8570.80
236_I259_L0.8560.80
224_N262_T0.8530.80
160_V202_A0.8530.80
555_S568_P0.8490.80
66_Y94_S0.8480.80
88_A125_Y0.8460.79
225_E229_N0.8440.79
486_L490_Y0.8430.79
303_Q306_R0.8410.79
205_D209_Q0.8410.79
457_L468_G0.8400.79
40_I76_L0.8400.79
74_F102_A0.8400.79
477_I488_V0.8390.79
553_G574_A0.8390.79
389_I447_A0.8360.79
242_F246_I0.8350.79
24_A147_I0.8350.79
480_G493_Y0.8330.78
341_D353_P0.8320.78
481_E486_L0.8270.78
197_L351_P0.8270.78
65_A77_T0.8260.78
310_H332_K0.8260.78
301_Y306_R0.8250.78
232_E255_K0.8240.78
109_D115_S0.8240.78
426_I488_V0.8230.78
386_S427_P0.8190.77
137_Y260_R0.8170.77
463_S472_S0.8160.77
455_L458_V0.8150.77
94_S131_I0.8140.77
198_V201_N0.8120.77
132_P160_V0.8110.77
595_A600_G0.8110.77
483_A489_K0.8110.77
101_G131_I0.8070.76
481_E487_G0.8040.76
144_D181_S0.8030.76
466_M472_S0.8030.76
358_P580_T0.8020.76
8_K174_P0.8000.76
503_I535_N0.8000.76
471_P484_K0.7980.75
81_H120_Q0.7960.75
567_I575_E0.7960.75
478_D490_Y0.7960.75
94_S103_L0.7960.75
283_L330_F0.7960.75
196_V201_N0.7940.75
231_S278_N0.7940.75
275_A279_S0.7920.75
198_V203_R0.7910.75
11_I177_L0.7910.75
520_A524_A0.7900.75
30_A65_A0.7880.74
325_K357_C0.7860.74
562_T586_A0.7840.74
586_A590_I0.7840.74
576_I596_I0.7820.74
151_K155_K0.7800.74
141_S262_T0.7790.74
66_Y407_T0.7780.74
490_Y516_N0.7780.74
31_G41_I0.7740.73
259_L276_V0.7740.73
482_V490_Y0.7670.72
19_F78_T0.7670.72
248_A363_R0.7650.72
464_T469_Q0.7610.72
293_E340_T0.7600.72
133_V264_P0.7550.71
550_K593_F0.7540.71
195_Y199_P0.7530.71
172_R391_C0.7510.71
457_L467_T0.7510.71
27_S73_A0.7500.71
463_S473_P0.7480.71
228_D278_N0.7480.71
205_D212_R0.7470.70
235_I330_F0.7470.70
196_V393_T0.7470.70
513_V528_C0.7460.70
458_V465_A0.7420.70
544_A596_I0.7420.70
315_V321_M0.7420.70
325_K345_V0.7410.70
244_Y326_V0.7380.70
217_E269_K0.7370.69
436_F482_V0.7360.69
24_A150_F0.7340.69
40_I44_L0.7340.69
444_L483_A0.7300.69
44_L52_A0.7290.69
261_L268_P0.7280.68
28_V68_A0.7280.68
588_V597_S0.7260.68
458_V473_P0.7260.68
269_K273_L0.7240.68
457_L464_T0.7210.68
320_E325_K0.7200.68
104_V162_F0.7170.67
19_F177_L0.7160.67
221_E275_A0.7160.67
364_S367_I0.7150.67
99_V153_S0.7140.67
550_K597_S0.7130.67
445_A486_L0.7120.67
477_I490_Y0.7120.67
457_L461_N0.7120.67
460_D468_G0.7100.67
238_S292_V0.7090.66
41_I44_L0.7090.66
487_G493_Y0.7050.66
77_T103_L0.7040.66
495_D498_D0.7040.66
136_P142_A0.7030.66
462_R472_S0.7030.66
134_V263_T0.7020.66
222_G225_E0.7020.66
520_A523_I0.7020.66
447_A454_M0.6980.65
465_A471_P0.6980.65
245_V249_I0.6970.65
484_K493_Y0.6970.65
455_L459_L0.6970.65
551_C591_C0.6950.65
197_L205_D0.6950.65
461_N468_G0.6950.65
462_R469_Q0.6940.65
460_D470_Q0.6940.65
408_D411_S0.6920.65
437_F542_P0.6920.65
400_F403_Q0.6880.64
98_G157_K0.6870.64
91_L103_L0.6840.64
369_L430_V0.6830.64
296_V309_L0.6830.64
245_V330_F0.6820.63
597_S600_G0.6810.63
363_R369_L0.6800.63
22_L48_G0.6790.63
389_I470_Q0.6780.63
596_I599_K0.6770.63
59_K110_D0.6770.63
360_C433_D0.6770.63
483_A490_Y0.6770.63
106_V164_S0.6760.63
480_G525_K0.6760.63
22_L50_I0.6750.63
479_I490_Y0.6740.63
85_N88_A0.6740.63
283_L329_A0.6710.62
461_N464_T0.6700.62
29_A44_L0.6700.62
158_H212_R0.6700.62
21_A104_V0.6690.62
300_L303_Q0.6660.62
101_G154_N0.6650.62
211_K220_V0.6620.61
457_L474_S0.6620.61
153_S158_H0.6600.61
479_I489_K0.6600.61
106_V162_F0.6590.61
155_K219_E0.6580.61
270_R273_L0.6570.61
37_S108_A0.6570.61
133_V161_I0.6570.61
461_N470_Q0.6550.60
124_Y127_L0.6530.60
45_M471_P0.6530.60
272_I299_L0.6530.60
272_I276_V0.6530.60
208_E211_K0.6520.60
484_K492_R0.6520.60
222_G227_I0.6510.60
480_G523_I0.6510.60
426_I493_Y0.6510.60
157_K194_R0.6500.60
248_A327_Y0.6500.60
316_S325_K0.6500.60
321_M325_K0.6460.59
188_V192_P0.6450.59
486_L491_V0.6450.59
216_I219_E0.6440.59
12_L172_R0.6440.59
248_A252_L0.6440.59
182_R216_I0.6430.59
76_L150_F0.6430.59
545_I548_L0.6430.59
203_R206_R0.6420.59
488_V521_V0.6420.59
148_E151_K0.6420.59
459_L473_P0.6410.59
482_V489_K0.6410.59
152_L160_V0.6390.58
228_D231_S0.6390.58
593_F598_L0.6380.58
132_P153_S0.6370.58
362_H365_S0.6370.58
504_R507_S0.6360.58
204_R208_E0.6350.58
15_E19_F0.6340.58
552_T592_P0.6340.58
277_S305_V0.6330.58
20_G143_H0.6290.57
85_N92_I0.6280.57
476_E486_L0.6280.57
13_G17_I0.6280.57
109_D113_M0.6270.57
9_R19_F0.6270.57
273_L299_L0.6270.57
62_F91_L0.6270.57
483_A491_V0.6260.57
213_W265_V0.6250.57
148_E213_W0.6240.57
585_G589_P0.6220.56
160_V206_R0.6200.56
112_S319_G0.6190.56
293_E341_D0.6180.56
38_T42_E0.6180.56
301_Y304_G0.6180.56
135_E238_S0.6180.56
544_A585_G0.6170.56
487_G492_R0.6160.56
157_K191_N0.6150.56
461_N465_A0.6130.55
19_F180_P0.6120.55
412_S431_I0.6110.55
62_F90_P0.6110.55
551_C554_C0.6090.55
293_E297_K0.6080.55
293_E353_P0.6070.55
290_P294_Y0.6070.55
204_R222_G0.6050.54
92_I129_A0.6040.54
124_Y128_H0.6020.54
224_N259_L0.6020.54
481_E489_K0.6020.54
235_I248_A0.6020.54
207_V214_E0.6020.54
566_I574_A0.6000.54
487_G494_V0.6000.54
41_I78_T0.6000.54
29_A50_I0.5980.54
339_V353_P0.5970.53
232_E254_I0.5970.53
88_A129_A0.5960.53
195_Y198_V0.5950.53
235_I283_L0.5940.53
158_H202_A0.5940.53
193_K196_V0.5930.53
433_D445_A0.5930.53
343_L346_P0.5910.53
98_G191_N0.5900.53
242_F258_I0.5890.52
505_E513_V0.5890.52
21_A44_L0.5880.52
227_I246_I0.5880.52
80_K106_V0.5870.52
283_L311_G0.5860.52
502_S507_S0.5850.52
178_K182_R0.5850.52
228_D255_K0.5840.52
127_L295_Q0.5840.52
271_L275_A0.5840.52
138_D168_I0.5820.52
332_K338_I0.5820.52
297_K302_D0.5810.51
268_P299_L0.5810.51
277_S280_K0.5800.51
65_A103_L0.5800.51
335_G338_I0.5800.51
229_N257_N0.5800.51
395_G398_P0.5780.51
226_L229_N0.5780.51
58_E83_G0.5760.51
62_F94_S0.5750.51
462_R473_P0.5750.51
11_I25_G0.5740.51
503_I507_S0.5740.51
178_K183_P0.5730.50
390_G466_M0.5710.50
207_V221_E0.5710.50
262_T271_L0.5700.50
134_V148_E0.5690.50
214_E221_E0.5690.50
81_H118_N0.5680.50
204_R207_V0.5680.50
461_N473_P0.5680.50
224_N271_L0.5670.50
55_S62_F0.5670.50
65_A94_S0.5670.50
460_D465_A0.5660.50
232_E281_R0.5660.50
389_I474_S0.5660.50
96_Y118_N0.5650.49
510_L514_K0.5640.49
210_L318_V0.5630.49
152_L205_D0.5630.49
293_E311_G0.5630.49
11_I19_F0.5630.49
269_K272_I0.5620.49
20_G136_P0.5610.49
226_L260_R0.5610.49
242_F245_V0.5610.49
283_L332_K0.5590.49
39_E389_I0.5590.49
460_D474_S0.5580.49
360_C438_H0.5560.48
248_A323_L0.5560.48
325_K329_A0.5560.48
331_S334_F0.5560.48
455_L464_T0.5560.48
460_D472_S0.5550.48
476_E489_K0.5550.48
481_E490_Y0.5550.48
444_L521_V0.5550.48
94_S105_I0.5550.48
555_S574_A0.5520.48
466_M471_P0.5520.48
28_V422_A0.5510.48
136_P146_T0.5510.48
480_G492_R0.5510.48
480_G490_Y0.5500.48
11_I175_V0.5500.48
44_L78_T0.5500.48
421_R452_T0.5500.48
207_V210_L0.5490.48
18_A37_S0.5490.48
30_A75_A0.5480.47
459_L471_P0.5480.47
510_L516_N0.5480.47
332_K339_V0.5460.47
29_A40_I0.5450.47
165_T169_G0.5440.47
546_V574_A0.5440.47
76_L106_V0.5430.47
545_I578_N0.5430.47
197_L200_E0.5420.47
435_T443_A0.5400.46
148_E222_G0.5390.46
512_W516_N0.5390.46
109_D195_Y0.5390.46
182_R185_M0.5380.46
311_G333_F0.5380.46
11_I143_H0.5370.46
356_L438_H0.5370.46
417_N452_T0.5360.46
385_I430_V0.5360.46
210_L213_W0.5360.46
463_S469_Q0.5360.46
20_G78_T0.5360.46
59_K87_A0.5360.46
149_A162_F0.5350.46
21_A25_G0.5350.46
447_A456_V0.5350.46
301_Y309_L0.5350.46
331_S358_P0.5340.46
207_V215_R0.5330.46
588_V598_L0.5330.46
416_A427_P0.5310.45
302_D305_V0.5310.45
134_V160_V0.5300.45
462_R476_E0.5300.45
461_N474_S0.5300.45
360_C470_Q0.5290.45
359_G433_D0.5290.45
360_C434_S0.5290.45
362_H366_F0.5280.45
283_L315_V0.5280.45
98_G158_H0.5280.45
235_I329_A0.5280.45
416_A429_A0.5280.45
550_K596_I0.5280.45
368_D372_A0.5280.45
475_K490_Y0.5270.45
328_Y331_S0.5270.45
112_S320_E0.5260.45
143_H173_G0.5260.45
488_V492_R0.5260.45
414_G417_N0.5260.45
109_D112_S0.5250.45
489_K518_Q0.5240.44
357_C467_T0.5240.44
134_V578_N0.5240.44
282_V307_V0.5210.44
42_E46_K0.5210.44
477_I491_V0.5210.44
233_N256_A0.5200.44
70_I121_D0.5200.44
537_E541_L0.5190.44
157_K528_C0.5190.44
556_I593_F0.5190.44
476_E491_V0.5180.44
155_K212_R0.5170.44
284_I296_V0.5170.44
273_L300_L0.5170.44
384_F427_P0.5170.44
357_C361_P0.5160.44
137_Y246_I0.5130.43
222_G270_R0.5130.43
107_S161_I0.5130.43
281_R334_F0.5120.43
457_L524_A0.5110.43
457_L473_P0.5110.43
365_S369_L0.5110.43
201_N204_R0.5110.43
360_C391_C0.5110.43
230_D337_D0.5110.43
155_K277_S0.5110.43
387_G403_Q0.5100.43
264_P295_Q0.5100.43
93_S118_N0.5100.43
29_A41_I0.5100.43
556_I590_I0.5100.43
213_W224_N0.5090.43
186_G212_R0.5090.43
223_L247_D0.5090.43
489_K492_R0.5080.43
300_L306_R0.5080.43
510_L528_C0.5070.42
92_I188_V0.5070.42
35_T38_T0.5070.42
550_K594_K0.5070.42
119_E166_T0.5060.42
362_H464_T0.5060.42
517_K520_A0.5050.42
120_Q170_H0.5050.42
461_N466_M0.5050.42
23_S147_I0.5040.42
37_S41_I0.5030.42
548_L575_E0.5030.42
458_V469_Q0.5020.42
124_Y291_I0.5020.42
455_L463_S0.5010.42
532_V541_L0.5010.42
257_N278_N0.5010.42
357_C470_Q0.5010.42
113_M118_N0.5000.42
369_L457_L0.5000.42
554_C591_C0.5000.42
30_A446_N0.5000.42
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c42A 2 0.9755 100 0.541 Contact Map
5c4iA 2 0.5686 100 0.731 Contact Map
1yd7A 1 0.2598 100 0.756 Contact Map
1ybhA 4 0.8317 100 0.817 Contact Map
2pgnA 4 0.8366 100 0.818 Contact Map
4rjjA 5 0.799 100 0.819 Contact Map
1ozhA 4 0.7925 100 0.821 Contact Map
2ihtA 4 0.7925 100 0.821 Contact Map
3eyaA 5 0.7761 100 0.829 Contact Map
1v5eA 4 0.8562 100 0.831 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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