Q97WK5 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97WK5 - Uncharacterized protein

UniProt:	Q97WK5	Sequences: MLWLLMTTGKCNLKCDYCGGSFPDNVVPYGIKYDINSVKKLIEKDKDSTIIFYGGEPLLNYKFVMAVLDNVRAKRYGIQTNGIAVRLLPERYWRKINVALLSIDGREEITNKHRGKGIYKAVLRSAKYLKDLGVETIARMTVTQDTDIFTDVMHLIDLGLFDKVHWQLDVIWSEEWDFKSWSFSYLNGIKRLTDYFLSELRKGRVVKIIPILGVISAHFFEGYKGSPCGAGYSSVTVTPDGRILSCPIAVREKWAELGNVNLGYRLLEDPLPDDCKRCEFKRYCGGRCLYAQKERYWGEEGFKAVDEVNKEYLRTVLSIIPEIERLIRDGYIRLSDLYYNPILDSTEIIP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	350 (301)
Sequences:	7068 (5531)
Seq/√Len:	318.8

ECOLI - ASLB YDEM MOAA
BACSU - ALBA SKFB MOAA YYDG
HALSA - Q9HQF5 MOAA Q9HQF7
SULSO - Q97WK5 Q97XA7 Q97XS7 Q97XZ2 Q7LXV3 Q97XA6 Q97XS8 Q97WC3 Q97Y04 MOAA Q980E0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
107_E	120_K	5.914	1.00
13_L	83_I	4.048	1.00
35_I	70_N	3.457	1.00
39_K	70_N	3.392	1.00
111_N	117_G	3.079	1.00
12_N	81_N	3.034	1.00
87_L	128_Y	3.029	1.00
33_Y	261_N	2.961	1.00
30_G	33_Y	2.907	1.00
127_K	159_G	2.861	1.00
242_R	259_N	2.801	1.00
91_R	132_L	2.761	1.00
246_C	288_C	2.693	1.00
228_C	246_C	2.666	1.00
119_Y	155_L	2.660	1.00
104_D	114_R	2.579	1.00
242_R	256_E	2.530	1.00
31_I	66_A	2.498	1.00
106_R	109_I	2.388	1.00
36_N	40_K	2.377	1.00
39_K	74_K	2.319	1.00
148_I	151_D	2.269	1.00
82_G	101_L	2.171	1.00
238_T	242_R	2.133	1.00
35_I	66_A	2.117	1.00
106_R	148_I	2.100	1.00
259_N	262_L	2.091	1.00
34_D	67_V	2.087	1.00
10_K	28_P	2.031	1.00
87_L	131_D	1.989	1.00
154_H	158_L	1.981	1.00
109_I	148_I	1.965	1.00
128_Y	131_D	1.952	1.00
3_W	41_L	1.899	1.00
70_N	73_A	1.898	1.00
107_E	111_N	1.860	1.00
86_R	89_P	1.804	1.00
138_A	156_I	1.778	1.00
127_K	131_D	1.765	1.00
101_L	126_A	1.764	1.00
70_N	74_K	1.756	1.00
12_N	84_A	1.748	1.00
31_I	35_I	1.714	1.00
87_L	132_L	1.700	1.00
29_Y	33_Y	1.686	1.00
71_V	76_Y	1.681	1.00
112_K	145_D	1.674	1.00
121_A	124_R	1.665	1.00
150_T	191_R	1.651	1.00
69_D	73_A	1.650	1.00
52_F	76_Y	1.640	1.00
122_V	125_S	1.635	1.00
110_T	118_I	1.617	1.00
151_D	154_H	1.607	1.00
184_S	188_G	1.605	1.00
65_M	92_Y	1.583	1.00
89_P	93_W	1.564	1.00
155_L	159_G	1.549	1.00
28_P	60_N	1.548	1.00
58_L	78_I	1.543	1.00
94_R	132_L	1.523	1.00
79_Q	100_L	1.505	1.00
187_N	191_R	1.496	1.00
35_I	39_K	1.484	1.00
101_L	125_S	1.479	1.00
50_I	71_V	1.471	1.00
90_E	128_Y	1.471	1.00
33_Y	36_N	1.466	1.00
140_M	152_V	1.465	1.00
72_R	97_N	1.452	1.00
124_R	127_K	1.448	1.00
17_Y	104_D	1.424	1.00
113_H	143_T	1.424	1.00
154_H	195_Y	1.414	1.00
107_E	119_Y	1.407	1.00
127_K	130_K	1.400	1.00
238_T	244_L	1.390	1.00
190_K	194_D	1.383	1.00
105_G	109_I	1.376	1.00
60_N	67_V	1.375	1.00
90_E	132_L	1.354	1.00
124_R	128_Y	1.353	1.00
16_D	112_K	1.346	1.00
99_A	129_L	1.342	1.00
66_A	69_D	1.342	1.00
111_N	114_R	1.321	1.00
128_Y	132_L	1.318	1.00
195_Y	198_S	1.311	1.00
29_Y	34_D	1.307	1.00
12_N	56_E	1.281	1.00
90_E	94_R	1.275	1.00
7_T	52_F	1.275	1.00
228_C	288_C	1.272	1.00
58_L	84_A	1.264	1.00
69_D	92_Y	1.252	1.00
138_A	161_F	1.249	1.00
140_M	164_V	1.240	1.00
38_V	71_V	1.222	1.00
88_L	92_Y	1.218	1.00
123_L	159_G	1.212	1.00
9_G	239_P	1.208	1.00
52_F	71_V	1.197	1.00
95_K	98_V	1.196	1.00
185_Y	188_G	1.196	1.00
85_V	90_E	1.194	1.00
144_Q	184_S	1.192	1.00
29_Y	37_S	1.181	1.00
120_K	124_R	1.178	1.00
102_S	141_T	1.164	1.00
88_L	91_R	1.164	1.00
62_K	66_A	1.156	1.00
19_G	53_Y	1.155	1.00
103_I	138_A	1.153	1.00
123_L	155_L	1.152	1.00
106_R	151_D	1.152	1.00
195_Y	199_E	1.146	1.00
153_M	157_D	1.146	1.00
154_H	157_D	1.139	1.00
38_V	74_K	1.130	1.00
5_L	34_D	1.125	1.00
110_T	122_V	1.125	1.00
130_K	160_L	1.119	1.00
110_T	114_R	1.113	1.00
111_N	118_I	1.110	1.00
187_N	190_K	1.107	1.00
203_G	206_V	1.106	1.00
36_N	39_K	1.105	1.00
272_P	298_G	1.093	1.00
65_M	95_K	1.085	1.00
13_L	118_I	1.077	1.00
105_G	119_Y	1.075	1.00
156_I	161_F	1.071	1.00
186_L	190_K	1.068	1.00
123_L	127_K	1.066	1.00
129_L	134_V	1.060	1.00
94_R	133_G	1.055	1.00
16_D	113_H	1.055	1.00
87_L	91_R	1.054	1.00
125_S	128_Y	1.047	1.00
36_N	261_N	1.045	1.00
66_A	70_N	1.036	1.00
119_Y	123_L	1.035	1.00
60_N	63_F	1.035	1.00
12_N	83_I	1.029	1.00
72_R	76_Y	1.024	1.00
235_V	264_Y	1.022	1.00
284_C	288_C	1.021	1.00
184_S	187_N	1.006	1.00
249_A	290_Y	1.004	1.00
58_L	89_P	0.994	1.00
289_L	292_Q	0.987	1.00
157_D	199_E	0.983	1.00
101_L	129_L	0.978	1.00
150_T	195_Y	0.976	1.00
100_L	139_R	0.974	1.00
41_L	50_I	0.971	1.00
94_R	134_V	0.971	1.00
89_P	92_Y	0.970	1.00
78_I	93_W	0.968	1.00
72_R	95_K	0.965	1.00
126_A	136_T	0.963	1.00
273_D	276_K	0.957	1.00
53_Y	79_Q	0.955	1.00
275_C	278_C	0.955	1.00
8_T	28_P	0.952	1.00
106_R	155_L	0.951	1.00
43_E	74_K	0.947	1.00
274_D	302_F	0.942	1.00
61_Y	65_M	0.937	1.00
189_I	192_L	0.935	1.00
49_T	75_R	0.931	1.00
105_G	114_R	0.930	1.00
121_A	125_S	0.927	1.00
49_T	77_G	0.926	1.00
85_V	129_L	0.926	1.00
92_Y	96_I	0.926	1.00
65_M	88_L	0.923	1.00
27_V	240_D	0.914	1.00
58_L	125_S	0.910	1.00
68_L	92_Y	0.903	1.00
17_Y	113_H	0.902	1.00
31_I	62_K	0.899	1.00
79_Q	247_P	0.894	1.00
78_I	99_A	0.893	1.00
56_E	80_T	0.889	1.00
244_L	256_E	0.889	1.00
5_L	37_S	0.885	1.00
150_T	154_H	0.884	1.00
99_A	134_V	0.883	1.00
85_V	125_S	0.882	1.00
178_F	181_W	0.876	1.00
167_Q	170_V	0.872	1.00
37_S	237_V	0.872	1.00
191_R	195_Y	0.870	1.00
152_V	156_I	0.870	1.00
183_F	187_N	0.868	1.00
179_K	182_S	0.864	1.00
126_A	138_A	0.864	1.00
185_Y	189_I	0.864	1.00
7_T	60_N	0.859	1.00
90_E	125_S	0.858	1.00
8_T	60_N	0.855	1.00
56_E	81_N	0.855	1.00
81_N	84_A	0.849	1.00
130_K	136_T	0.848	1.00
110_T	117_G	0.848	1.00
169_D	173_S	0.845	1.00
185_Y	196_F	0.844	1.00
110_T	119_Y	0.843	1.00
69_D	95_K	0.841	1.00
72_R	96_I	0.840	1.00
79_Q	139_R	0.840	1.00
243_I	264_Y	0.836	1.00
11_C	15_C	0.832	1.00
11_C	18_C	0.822	1.00
107_E	117_G	0.821	1.00
37_S	40_K	0.816	1.00
17_Y	114_R	0.815	1.00
284_C	306_D	0.813	1.00
20_G	53_Y	0.812	1.00
6_M	236_T	0.811	1.00
40_K	44_K	0.808	1.00
275_C	284_C	0.805	1.00
191_R	194_D	0.804	1.00
15_C	18_C	0.803	1.00
253_K	256_E	0.801	1.00
87_L	90_E	0.800	1.00
38_V	50_I	0.796	1.00
86_R	92_Y	0.793	1.00
91_R	94_R	0.792	1.00
273_D	277_R	0.792	1.00
12_N	59_L	0.791	1.00
111_N	119_Y	0.781	1.00
32_K	36_N	0.777	1.00
53_Y	247_P	0.777	1.00
129_L	136_T	0.771	1.00
37_S	41_L	0.770	1.00
68_L	96_I	0.770	1.00
3_W	235_V	0.766	0.99
138_A	164_V	0.765	0.99
208_I	211_I	0.765	0.99
6_M	53_Y	0.762	0.99
103_I	119_Y	0.760	0.99
65_M	89_P	0.760	0.99
130_K	162_D	0.759	0.99
205_V	208_I	0.758	0.99
211_I	214_V	0.756	0.99
192_L	196_F	0.756	0.99
35_I	73_A	0.754	0.99
103_I	123_L	0.752	0.99
155_L	158_L	0.751	0.99
52_F	68_L	0.751	0.99
126_A	161_F	0.751	0.99
210_P	213_G	0.749	0.99
105_G	110_T	0.748	0.99
258_G	263_G	0.745	0.99
143_T	146_T	0.743	0.99
302_F	306_D	0.741	0.99
83_I	125_S	0.740	0.99
259_N	263_G	0.739	0.99
108_E	112_K	0.737	0.99
135_E	162_D	0.737	0.99
56_E	82_G	0.731	0.99
274_D	303_K	0.729	0.99
4_L	234_S	0.728	0.99
245_S	249_A	0.725	0.99
67_V	71_V	0.722	0.99
104_D	110_T	0.718	0.99
50_I	76_Y	0.718	0.99
100_L	137_I	0.717	0.99
34_D	37_S	0.715	0.99
68_L	76_Y	0.714	0.99
33_Y	37_S	0.711	0.99
202_K	206_V	0.710	0.99
296_Y	301_G	0.710	0.99
80_T	101_L	0.709	0.99
226_S	230_A	0.706	0.99
90_E	93_W	0.706	0.99
7_T	63_F	0.706	0.99
31_I	70_N	0.706	0.99
237_V	243_I	0.706	0.99
34_D	38_V	0.702	0.99
6_M	239_P	0.700	0.99
194_D	197_L	0.699	0.99
204_R	209_I	0.698	0.99
263_G	267_L	0.697	0.99
188_G	191_R	0.693	0.99
51_I	79_Q	0.692	0.99
225_G	228_C	0.692	0.99
203_G	207_K	0.688	0.99
41_L	47_D	0.686	0.99
6_M	20_G	0.683	0.99
56_E	59_L	0.682	0.99
169_D	175_E	0.682	0.99
10_K	26_V	0.681	0.99
62_K	65_M	0.681	0.99
236_T	247_P	0.681	0.99
7_T	67_V	0.677	0.99
35_I	74_K	0.677	0.99
32_K	35_I	0.677	0.99
92_Y	95_K	0.676	0.99
51_I	77_G	0.676	0.99
75_R	97_N	0.676	0.99
140_M	156_I	0.672	0.99
58_L	63_F	0.672	0.99
130_K	161_F	0.668	0.99
26_V	29_Y	0.667	0.99
281_K	285_G	0.663	0.99
53_Y	100_L	0.663	0.99
52_F	67_V	0.659	0.98
63_F	68_L	0.658	0.98
47_D	75_R	0.656	0.98
14_K	21_S	0.655	0.98
204_R	208_I	0.654	0.98
3_W	237_V	0.654	0.98
222_G	225_G	0.653	0.98
101_L	122_V	0.649	0.98
120_K	123_L	0.649	0.98
102_S	114_R	0.647	0.98
272_P	302_F	0.645	0.98
193_T	196_F	0.644	0.98
59_L	84_A	0.644	0.98
17_Y	141_T	0.644	0.98
34_D	60_N	0.643	0.98
156_I	159_G	0.641	0.98
226_S	229_G	0.637	0.98
118_I	122_V	0.634	0.98
126_A	159_G	0.632	0.98
26_V	30_G	0.629	0.98
275_C	306_D	0.627	0.98
287_R	303_K	0.625	0.98
148_I	152_V	0.624	0.98
86_R	125_S	0.624	0.98
71_V	74_K	0.623	0.98
61_Y	89_P	0.622	0.98
153_M	164_V	0.620	0.98
105_G	148_I	0.616	0.98
224_K	227_P	0.615	0.98
142_V	149_F	0.611	0.98
38_V	52_F	0.607	0.97
209_I	213_G	0.607	0.97
241_G	259_N	0.606	0.97
61_Y	64_V	0.605	0.97
85_V	89_P	0.603	0.97
243_I	263_G	0.602	0.97
213_G	217_A	0.601	0.97
83_I	121_A	0.600	0.97
39_K	43_E	0.598	0.97
79_Q	248_I	0.597	0.97
235_V	265_R	0.596	0.97
86_R	90_E	0.595	0.97
167_Q	173_S	0.595	0.97
139_R	247_P	0.595	0.97
256_E	259_N	0.594	0.97
61_Y	92_Y	0.594	0.97
22_F	174_E	0.594	0.97
82_G	125_S	0.590	0.97
114_R	118_I	0.590	0.97
68_L	71_V	0.588	0.97
17_Y	20_G	0.584	0.97
149_F	191_R	0.584	0.97
31_I	60_N	0.582	0.97
20_G	236_T	0.582	0.97
242_R	258_G	0.581	0.97
4_L	247_P	0.580	0.97
278_C	306_D	0.580	0.97
299_E	302_F	0.579	0.97
58_L	83_I	0.578	0.97
209_I	212_L	0.578	0.97
31_I	34_D	0.577	0.96
188_G	192_L	0.576	0.96
86_R	93_W	0.571	0.96
255_A	293_K	0.568	0.96
103_I	122_V	0.566	0.96
306_D	309_N	0.566	0.96
104_D	141_T	0.565	0.96
53_Y	139_R	0.563	0.96
184_S	196_F	0.562	0.96
185_Y	192_L	0.560	0.96
139_R	167_Q	0.560	0.96
140_M	166_W	0.560	0.96
147_D	188_G	0.558	0.96
20_G	247_P	0.557	0.96
185_Y	193_T	0.556	0.96
93_W	98_V	0.554	0.96
17_Y	53_Y	0.554	0.96
149_F	153_M	0.553	0.96
202_K	208_I	0.552	0.95
65_M	91_R	0.551	0.95
33_Y	40_K	0.551	0.95
37_S	260_V	0.550	0.95
111_N	116_K	0.550	0.95
125_S	129_L	0.549	0.95
78_I	96_I	0.547	0.95
186_L	196_F	0.546	0.95
31_I	67_V	0.545	0.95
141_T	169_D	0.544	0.95
188_G	196_F	0.544	0.95
234_S	247_P	0.543	0.95
4_L	51_I	0.541	0.95
156_I	164_V	0.540	0.95
230_A	246_C	0.538	0.95
189_I	193_T	0.538	0.95
296_Y	302_F	0.536	0.95
130_K	159_G	0.536	0.95
34_D	52_F	0.532	0.95
292_Q	304_A	0.531	0.94
189_I	196_F	0.531	0.94
183_F	186_L	0.530	0.94
210_P	214_V	0.530	0.94
298_G	301_G	0.529	0.94
207_K	210_P	0.528	0.94
196_F	199_E	0.527	0.94
147_D	150_T	0.527	0.94
89_P	94_R	0.527	0.94
60_N	66_A	0.525	0.94
293_K	296_Y	0.524	0.94
177_D	180_S	0.523	0.94
17_Y	143_T	0.523	0.94
6_M	139_R	0.522	0.94
109_I	112_K	0.520	0.94
164_V	168_L	0.520	0.94
194_D	198_S	0.520	0.94
7_T	34_D	0.520	0.94
153_M	199_E	0.519	0.94
149_F	166_W	0.518	0.94
303_K	309_N	0.517	0.94
223_Y	226_S	0.516	0.94
4_L	53_Y	0.514	0.93
249_A	255_A	0.514	0.93
222_G	226_S	0.513	0.93
304_A	307_E	0.511	0.93
203_G	208_I	0.511	0.93
142_V	166_W	0.511	0.93
245_S	248_I	0.510	0.93
175_E	178_F	0.509	0.93
115_G	118_I	0.508	0.93
35_I	40_K	0.508	0.93
207_K	212_L	0.508	0.93
6_M	9_G	0.507	0.93
305_V	308_V	0.507	0.93
206_V	211_I	0.507	0.93
278_C	284_C	0.507	0.93
54_G	57_P	0.507	0.93
221_E	224_K	0.506	0.93
292_Q	298_G	0.506	0.93
222_G	227_P	0.505	0.93
243_I	258_G	0.504	0.93
255_A	258_G	0.504	0.93
136_T	161_F	0.503	0.93
147_D	184_S	0.501	0.93
5_L	17_Y	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4k36A	1	0.9629	100	0.318	Contact Map
1tv8A	2	0.78	100	0.534	Contact Map
4m7tA	1	0.6086	100	0.55	Contact Map
4rtbA	2	0.8886	100	0.58	Contact Map
4wcxA	1	0.9457	100	0.611	Contact Map
3c8fA	1	0.58	99.9	0.618	Contact Map
2z2uA	1	0.5629	99.9	0.646	Contact Map
2yx0A	1	0.6486	99.9	0.647	Contact Map
3rfaA	1	0.6514	99.9	0.664	Contact Map
2a5hA	4	0.7886	99.9	0.667	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0098 seconds.