GREMLIN Database
Q97WJ9 - Uncharacterized protein
UniProt: Q97WJ9 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 158 (134)
Sequences: 469 (385)
Seq/√Len: 33.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
93_V104_L5.9561.00
127_K136_E5.0141.00
33_D36_S3.0901.00
74_L78_D2.7351.00
135_R146_Y2.5591.00
108_G117_N2.4861.00
108_G123_S2.3870.99
75_S78_D2.2970.99
93_V117_N2.1500.99
136_E155_R2.0990.98
100_V128_Y1.9920.98
95_T100_V1.9830.98
26_E80_S1.8950.97
73_K78_D1.8810.97
98_L121_E1.8630.97
117_N149_G1.7340.95
98_L126_F1.7320.95
111_F119_K1.6800.94
84_L88_L1.6470.93
127_K156_I1.6290.93
65_V89_Q1.6190.93
144_C147_C1.5420.91
113_S126_F1.5290.91
143_E152_V1.4990.90
44_I48_K1.4250.87
40_L43_A1.4220.87
125_K134_K1.4120.87
79_I83_A1.4120.87
126_F155_R1.4060.86
142_G154_R1.3670.85
94_F125_K1.3480.84
126_F156_I1.3430.84
36_S66_L1.3420.84
73_K99_S1.3210.83
126_F153_K1.3130.82
93_V149_G1.3120.82
59_V79_I1.3110.82
113_S137_F1.3100.82
104_L125_K1.2900.81
96_D114_V1.2830.81
32_K37_R1.2680.80
24_T80_S1.2680.80
137_F145_P1.2680.80
104_L132_N1.2420.79
129_V134_K1.2410.79
94_F122_K1.2360.78
106_Q132_N1.2030.76
105_K111_F1.1890.76
85_A93_V1.1870.75
94_F104_L1.1730.75
138_N156_I1.1550.73
77_T80_S1.1530.73
114_V123_S1.1350.72
52_M91_S1.0950.69
110_Q125_K1.0890.69
144_C148_G1.0870.69
43_A53_K1.0860.69
132_N139_I1.0650.67
126_F141_H1.0630.67
88_L91_S1.0600.67
27_V31_I1.0470.66
64_K81_V1.0390.65
125_K131_V1.0350.65
66_L69_T1.0300.64
66_L70_K1.0230.64
137_F152_V1.0030.62
30_E66_L0.9940.62
131_V152_V0.9840.61
92_I109_I0.9820.61
122_K150_K0.9720.60
108_G118_K0.9650.59
96_D122_K0.9550.59
119_K129_V0.9520.58
143_E151_V0.9420.57
78_D83_A0.9410.57
122_K137_F0.9400.57
131_V149_G0.9390.57
138_N142_G0.9300.56
113_S122_K0.9290.56
53_K71_E0.9270.56
85_A88_L0.9170.55
129_V151_V0.9020.54
104_L140_D0.8920.53
31_I54_P0.8860.53
74_L83_A0.8780.52
94_F118_K0.8700.51
124_F153_K0.8620.51
48_K111_F0.8580.50
70_K75_S0.8560.50
65_V68_L0.8550.50
135_R145_P0.8460.49
103_I111_F0.8450.49
38_F42_I0.8440.49
49_V59_V0.8430.49
118_K149_G0.8360.49
65_V71_E0.8230.48
92_I96_D0.8200.47
31_I44_I0.8180.47
100_V114_V0.8100.46
132_N149_G0.8070.46
136_E153_K0.8010.46
105_K128_Y0.7980.45
113_S142_G0.7980.45
108_G141_H0.7980.45
111_F114_V0.7900.45
24_T58_S0.7890.45
96_D115_K0.7880.45
106_Q131_V0.7850.44
114_V131_V0.7790.44
104_L113_S0.7690.43
100_V110_Q0.7650.43
35_Y39_N0.7620.43
107_L150_K0.7540.42
137_F146_Y0.7520.42
98_L115_K0.7490.41
134_K143_E0.7460.41
127_K155_R0.7440.41
95_T111_F0.7440.41
92_I134_K0.7380.41
49_V55_S0.7370.40
99_S131_V0.7340.40
124_F142_G0.7310.40
146_Y150_K0.7250.40
63_T76_N0.7250.40
69_T78_D0.7220.39
106_Q123_S0.7180.39
21_V73_K0.7090.38
62_V65_V0.7070.38
94_F149_G0.7040.38
94_F121_E0.7000.38
110_Q123_S0.6990.37
27_V30_E0.6960.37
105_K131_V0.6960.37
93_V118_K0.6900.37
105_K119_K0.6870.37
53_K57_R0.6860.36
30_E54_P0.6800.36
106_Q117_N0.6660.35
70_K84_L0.6660.35
41_E48_K0.6640.35
109_I128_Y0.6640.35
101_Q113_S0.6570.34
32_K54_P0.6560.34
98_L120_V0.6540.34
75_S81_V0.6540.34
92_I119_K0.6530.34
98_L101_Q0.6520.34
31_I47_G0.6500.34
74_L81_V0.6490.34
80_S83_A0.6430.33
142_G149_G0.6420.33
55_S87_D0.6310.32
31_I36_S0.6210.32
97_D133_C0.6200.32
127_K137_F0.6190.31
69_T86_L0.6180.31
142_G150_K0.6130.31
96_D126_F0.6050.30
62_V69_T0.6030.30
99_S124_F0.6020.30
25_Q31_I0.6010.30
69_T74_L0.6000.30
54_P62_V0.5920.30
114_V150_K0.5860.29
72_R77_T0.5860.29
94_F107_L0.5850.29
34_K51_I0.5800.29
70_K88_L0.5780.29
128_Y152_V0.5780.29
36_S44_I0.5640.28
74_L77_T0.5600.27
103_I106_Q0.5590.27
110_Q153_K0.5580.27
142_G155_R0.5580.27
105_K118_K0.5560.27
107_L135_R0.5550.27
92_I127_K0.5500.27
36_S62_V0.5500.27
111_F141_H0.5480.27
70_K78_D0.5480.27
104_L115_K0.5440.26
78_D81_V0.5440.26
146_Y149_G0.5420.26
69_T83_A0.5410.26
100_V103_I0.5400.26
24_T27_V0.5370.26
136_E150_K0.5370.26
112_S142_G0.5350.26
78_D82_I0.5330.26
106_Q110_Q0.5300.25
47_G57_R0.5280.25
77_T83_A0.5270.25
120_V132_N0.5220.25
30_E70_K0.5190.25
96_D121_E0.5170.25
139_I155_R0.5150.24
133_C144_C0.5090.24
133_C147_C0.5090.24
33_D37_R0.5080.24
106_Q155_R0.5010.24
69_T75_S0.5000.24
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2lcqA 1 0.9557 100 0.503 Contact Map
2conA 1 0.2911 99.7 0.672 Contact Map
3ix7A 2 0.7025 98.3 0.83 Contact Map
3i8oA 2 0.7722 97.9 0.846 Contact Map
2kdxA 1 0.6392 96.6 0.878 Contact Map
2dokA 2 0.7278 96.4 0.881 Contact Map
1o4wA 2 0.7025 95.7 0.888 Contact Map
2fe1A 2 0.6519 93.7 0.899 Contact Map
4qiwP 1 0.1835 92.7 0.902 Contact Map
2apoB 1 0.2089 90.4 0.908 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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