FENR - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

FENR - Ferredoxin--NADP reductase

UniProt:	Q97WJ5	Sequences: MDEYDIVVIGGGPVGLFGTFYAGLRDMKTLLIDAQDELGGQLVSLYPEKIVYDVGGLAGIQAYELAQRLIEQAKMFGPDIKVNELADMIEKTNDNMWIVKTDKATYKTKTIFIAAGIGKIVPSRLGAKGEIEYENRGVYYTVRRKKDFEGKRVLIVGGGDSAVDWALTLAPVAKSVTLIHRRDQFRAHERSVKELFRVANVYVWHELKEVKGDGNKVTQAIIFDNRTKEEKVLDVDSVIISIGYKGDLGNIPKWGVTMKGRDIVVNGRMETNLPGVYAGGDIVQMEGSPKLALIAVGFAHAAIAISVAKKYVEPNASLFAGHSSEMDKFKPK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	332 (282)
Sequences:	59845 (42383)
Seq/√Len:	2523.9

ECOLI - RCLA TRXB AHPF HCAD STHA NORW GSHR DLDH DHNA PRET GLTD NIRB YGFT AEGA YGFK FADH
BACSU - FENR1 FENR2 DHNA YPDA TRXB CZCO DLDH3 DLDH2 YJLD YUMB DLDH1 YUTJ GLTB NASB NASD
HALSA - P82854 Q9HSN0 Q9HP48 DLDH Q9HR27 O54535
SULSO - FENR Q97V69 Q97W27 Q97XZ3 Q97VD9 Q97Z14 Q97WE3 Q97YT2 Q97Z19 Q97WG1 Q97VJ3 Q97Y24 Q97U72 Q97VQ4 Q97UP4 Q97UV0 Q97ZB4 Q980U1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
154_L	235_V	4.092	1.00
152_R	175_S	3.475	1.00
177_T	204_W	3.173	1.00
209_E	221_I	3.041	1.00
5_D	109_K	2.894	1.00
211_K	221_I	2.891	1.00
175_S	202_Y	2.843	1.00
219_Q	232_V	2.784	1.00
211_K	219_Q	2.519	1.00
266_N	270_E	2.512	1.00
5_D	28_K	2.489	1.00
221_I	232_V	2.388	1.00
152_R	236_D	2.384	1.00
204_W	231_K	2.366	1.00
6_I	22_A	2.336	1.00
154_L	179_I	2.325	1.00
224_D	231_K	2.308	1.00
30_L	81_K	2.285	1.00
18_G	112_F	2.275	1.00
123_S	245_K	2.255	1.00
7_V	32_I	2.243	1.00
257_T	264_V	2.211	1.00
206_E	223_F	2.205	1.00
128_K	209_E	2.191	1.00
4_Y	30_L	2.163	1.00
154_L	220_A	2.144	1.00
32_I	106_Y	2.140	1.00
208_K	223_F	2.133	1.00
98_I	105_T	2.129	1.00
112_F	308_A	2.116	1.00
152_R	177_T	2.115	1.00
193_K	197_R	2.036	1.00
7_V	106_Y	1.966	1.00
208_K	221_I	1.944	1.00
91_K	273_L	1.905	1.00
219_Q	234_D	1.886	1.00
100_K	105_T	1.848	1.00
5_D	30_L	1.832	1.00
110_T	275_G	1.772	1.00
211_K	232_V	1.753	1.00
181_R	206_E	1.698	1.00
259_K	262_D	1.693	1.00
108_T	111_I	1.687	1.00
7_V	99_V	1.685	1.00
118_G	247_D	1.674	1.00
14_V	279_G	1.672	1.00
152_R	234_D	1.669	1.00
177_T	202_Y	1.663	1.00
97_W	101_T	1.650	1.00
179_I	233_L	1.632	1.00
151_K	236_D	1.623	1.00
7_V	108_T	1.607	1.00
98_I	101_T	1.600	1.00
257_T	272_N	1.595	1.00
152_R	174_K	1.587	1.00
132_E	212_G	1.561	1.00
222_I	233_L	1.555	1.00
305_I	309_K	1.487	1.00
112_F	279_G	1.480	1.00
28_K	79_D	1.467	1.00
34_A	84_E	1.456	1.00
118_G	245_K	1.452	1.00
118_G	249_G	1.448	1.00
97_W	275_G	1.447	1.00
115_A	282_I	1.436	1.00
7_V	30_L	1.430	1.00
8_V	15_G	1.426	1.00
98_I	107_K	1.417	1.00
186_R	189_E	1.405	1.00
110_T	308_A	1.397	1.00
88_M	100_K	1.384	1.00
11_G	33_D	1.378	1.00
301_A	305_I	1.377	1.00
136_R	139_Y	1.369	1.00
277_Y	307_V	1.363	1.00
277_Y	311_Y	1.362	1.00
19_T	31_L	1.360	1.00
210_V	238_V	1.352	1.00
101_T	104_A	1.333	1.00
110_T	277_Y	1.328	1.00
101_T	106_Y	1.325	1.00
8_V	19_T	1.316	1.00
222_I	225_N	1.301	1.00
270_E	274_P	1.293	1.00
304_A	308_A	1.280	1.00
259_K	284_Q	1.276	1.00
222_I	231_K	1.269	1.00
153_V	169_L	1.266	1.00
126_G	130_E	1.262	1.00
177_T	235_V	1.262	1.00
259_K	264_V	1.250	1.00
158_G	180_H	1.230	1.00
72_Q	76_F	1.230	1.00
70_I	74_K	1.219	1.00
90_E	98_I	1.214	1.00
6_I	112_F	1.206	1.00
71_E	74_K	1.201	1.00
150_G	174_K	1.195	1.00
139_Y	142_V	1.194	1.00
30_L	106_Y	1.178	1.00
52_Y	55_G	1.178	1.00
21_Y	306_S	1.177	1.00
139_Y	143_R	1.170	1.00
114_A	279_G	1.164	1.00
91_K	276_V	1.153	1.00
135_N	140_Y	1.151	1.00
6_I	27_M	1.148	1.00
25_R	309_K	1.142	1.00
265_V	283_V	1.140	1.00
61_Q	64_E	1.137	1.00
14_V	297_G	1.135	1.00
21_Y	24_L	1.134	1.00
263_I	278_A	1.127	1.00
67_Q	71_E	1.119	1.00
170_A	201_V	1.117	1.00
273_L	276_V	1.113	1.00
149_E	174_K	1.111	1.00
163_V	178_L	1.111	1.00
89_I	111_I	1.105	1.00
96_M	101_T	1.100	1.00
303_I	307_V	1.096	1.00
179_I	222_I	1.072	1.00
136_R	140_Y	1.071	1.00
153_V	237_S	1.067	1.00
71_E	75_M	1.060	1.00
213_D	219_Q	1.056	1.00
22_A	305_I	1.042	1.00
4_Y	7_V	1.035	1.00
135_N	141_T	1.033	1.00
110_T	311_Y	1.026	1.00
135_N	139_Y	1.020	1.00
90_E	100_K	1.015	1.00
140_Y	143_R	1.006	1.00
136_R	142_V	1.003	1.00
170_A	175_S	1.003	1.00
279_G	304_A	1.001	1.00
96_M	99_V	0.999	1.00
156_V	238_V	0.995	1.00
23_G	78_P	0.995	1.00
263_I	282_I	0.995	1.00
42_L	45_L	0.989	1.00
25_R	306_S	0.988	1.00
96_M	100_K	0.984	1.00
153_V	174_K	0.983	1.00
195_L	198_V	0.981	1.00
40_G	45_L	0.980	1.00
9_I	113_I	0.979	1.00
87_D	100_K	0.978	1.00
36_D	83_N	0.977	1.00
137_G	140_Y	0.976	1.00
73_A	76_F	0.971	1.00
217_V	238_V	0.963	1.00
32_I	81_K	0.963	1.00
21_Y	25_R	0.961	1.00
32_I	86_A	0.948	1.00
53_D	56_G	0.946	1.00
162_A	180_H	0.944	1.00
297_G	301_A	0.944	1.00
173_A	176_V	0.939	1.00
166_A	178_L	0.936	1.00
167_L	171_P	0.935	1.00
9_I	115_A	0.931	1.00
213_D	216_K	0.930	1.00
190_R	193_K	0.929	1.00
6_I	110_T	0.929	1.00
21_Y	302_A	0.929	1.00
171_P	199_A	0.922	1.00
37_E	70_I	0.920	1.00
30_L	108_T	0.919	1.00
269_M	303_I	0.918	1.00
81_K	106_Y	0.918	1.00
88_M	253_K	0.907	1.00
202_Y	231_K	0.905	1.00
278_A	282_I	0.900	1.00
4_Y	28_K	0.900	1.00
213_D	234_D	0.900	1.00
207_L	220_A	0.900	1.00
141_T	144_R	0.899	1.00
270_E	311_Y	0.894	1.00
81_K	84_E	0.893	1.00
154_L	233_L	0.893	1.00
283_V	300_H	0.892	1.00
64_E	68_R	0.889	1.00
249_G	252_P	0.888	1.00
194_E	197_R	0.886	1.00
269_M	283_V	0.886	1.00
281_D	297_G	0.879	1.00
81_K	104_A	0.877	1.00
5_D	107_K	0.876	1.00
22_A	27_M	0.876	1.00
64_E	67_Q	0.873	1.00
40_G	44_S	0.871	1.00
18_G	279_G	0.870	1.00
39_G	42_L	0.870	1.00
30_L	79_D	0.863	1.00
155_I	166_A	0.856	1.00
5_D	27_M	0.855	1.00
137_G	141_T	0.852	1.00
20_F	24_L	0.851	1.00
258_M	264_V	0.850	1.00
168_T	172_V	0.848	1.00
269_M	304_A	0.847	1.00
265_V	278_A	0.847	1.00
136_R	141_T	0.844	1.00
277_Y	308_A	0.843	1.00
177_T	233_L	0.838	1.00
18_G	304_A	0.838	1.00
27_M	309_K	0.831	1.00
210_V	220_A	0.831	1.00
111_I	276_V	0.828	1.00
112_F	304_A	0.828	1.00
39_G	45_L	0.825	1.00
154_L	238_V	0.822	1.00
18_G	301_A	0.822	1.00
195_L	199_A	0.819	1.00
156_V	242_I	0.819	1.00
87_D	102_D	0.818	1.00
270_E	275_G	0.817	1.00
69_L	72_Q	0.814	1.00
204_W	233_L	0.813	1.00
15_G	114_A	0.812	1.00
156_V	240_I	0.812	1.00
268_R	307_V	0.811	1.00
137_G	142_V	0.802	1.00
265_V	269_M	0.798	1.00
4_Y	110_T	0.796	1.00
15_G	19_T	0.794	1.00
6_I	308_A	0.793	1.00
92_T	98_I	0.789	1.00
278_A	283_V	0.781	1.00
129_G	132_E	0.779	1.00
117_I	244_Y	0.774	1.00
22_A	308_A	0.774	1.00
8_V	18_G	0.773	1.00
139_Y	144_R	0.773	1.00
19_T	29_T	0.772	1.00
52_Y	56_G	0.764	1.00
96_M	107_K	0.763	1.00
212_G	217_V	0.762	1.00
39_G	44_S	0.759	1.00
151_K	174_K	0.759	1.00
9_I	86_A	0.758	1.00
66_A	70_I	0.754	1.00
113_I	282_I	0.750	1.00
23_G	29_T	0.749	1.00
83_N	102_D	0.744	1.00
73_A	78_P	0.743	1.00
158_G	185_F	0.743	1.00
84_E	102_D	0.743	1.00
143_R	146_K	0.743	1.00
179_I	204_W	0.742	1.00
56_G	60_I	0.741	1.00
65_L	68_R	0.741	1.00
40_G	43_V	0.733	1.00
304_A	307_V	0.733	1.00
63_Y	67_Q	0.732	1.00
275_G	311_Y	0.729	1.00
32_I	101_T	0.723	1.00
11_G	31_L	0.717	1.00
167_L	170_A	0.717	1.00
235_V	238_V	0.716	1.00
38_L	82_V	0.715	1.00
19_T	78_P	0.715	1.00
41_Q	45_L	0.713	1.00
296_V	300_H	0.713	1.00
159_G	243_G	0.711	1.00
5_D	106_Y	0.709	1.00
84_E	87_D	0.709	1.00
277_Y	304_A	0.707	1.00
212_G	216_K	0.706	1.00
141_T	145_K	0.706	1.00
194_E	198_V	0.705	1.00
190_R	194_E	0.703	1.00
22_A	29_T	0.695	1.00
302_A	306_S	0.695	1.00
137_G	240_I	0.694	1.00
279_G	308_A	0.692	1.00
204_W	222_I	0.690	1.00
191_S	194_E	0.690	1.00
156_V	207_L	0.690	1.00
152_R	235_V	0.689	1.00
8_V	114_A	0.688	1.00
99_V	103_K	0.687	1.00
170_A	199_A	0.687	1.00
110_T	312_V	0.683	1.00
41_Q	44_S	0.681	1.00
67_Q	70_I	0.680	1.00
180_H	183_D	0.679	1.00
184_Q	193_K	0.675	1.00
125_L	240_I	0.673	1.00
5_D	108_T	0.671	1.00
193_K	203_V	0.671	1.00
168_T	171_P	0.671	1.00
271_T	278_A	0.670	1.00
210_V	217_V	0.667	1.00
212_G	215_N	0.665	1.00
216_K	219_Q	0.665	1.00
270_E	307_V	0.664	1.00
129_G	209_E	0.660	1.00
72_Q	75_M	0.656	1.00
32_I	108_T	0.652	1.00
169_L	172_V	0.651	1.00
27_M	109_K	0.651	1.00
17_F	21_Y	0.649	1.00
52_Y	57_L	0.646	1.00
72_Q	77_G	0.646	1.00
97_W	103_K	0.645	1.00
56_G	59_G	0.645	1.00
299_A	302_A	0.645	1.00
97_W	273_L	0.645	1.00
113_I	250_N	0.641	1.00
17_F	301_A	0.638	1.00
90_E	96_M	0.638	1.00
165_W	239_I	0.637	1.00
23_G	77_G	0.633	1.00
97_W	100_K	0.633	1.00
165_W	168_T	0.632	1.00
127_A	130_E	0.630	1.00
18_G	305_I	0.628	1.00
183_D	205_H	0.627	1.00
130_E	240_I	0.624	1.00
124_R	240_I	0.624	1.00
57_L	60_I	0.622	1.00
270_E	277_Y	0.622	1.00
284_Q	300_H	0.618	1.00
4_Y	79_D	0.618	1.00
17_F	298_F	0.618	1.00
27_M	308_A	0.615	1.00
86_A	99_V	0.615	1.00
92_T	96_M	0.613	1.00
100_K	103_K	0.612	1.00
88_M	91_K	0.610	1.00
269_M	307_V	0.609	1.00
264_V	272_N	0.609	1.00
151_K	237_S	0.608	1.00
206_E	225_N	0.608	1.00
135_N	138_V	0.605	1.00
39_G	43_V	0.601	1.00
17_F	20_F	0.601	1.00
124_R	131_I	0.601	1.00
196_F	203_V	0.599	1.00
84_E	101_T	0.594	1.00
151_K	175_S	0.592	1.00
279_G	301_A	0.592	1.00
306_S	310_K	0.590	1.00
139_Y	237_S	0.589	1.00
33_D	82_V	0.588	1.00
6_I	305_I	0.587	1.00
170_A	200_N	0.586	1.00
54_V	57_L	0.585	1.00
265_V	268_R	0.584	1.00
14_V	114_A	0.583	1.00
4_Y	109_K	0.582	1.00
180_H	205_H	0.581	1.00
68_R	71_E	0.581	1.00
8_V	31_L	0.580	1.00
148_F	151_K	0.579	1.00
157_G	243_G	0.578	1.00
33_D	39_G	0.576	1.00
258_M	263_I	0.576	1.00
180_H	185_F	0.576	1.00
38_L	80_I	0.572	1.00
252_P	258_M	0.569	1.00
191_S	195_L	0.569	1.00
219_Q	222_I	0.564	1.00
69_L	73_A	0.564	1.00
91_K	97_W	0.564	1.00
180_H	203_V	0.563	1.00
138_V	142_V	0.560	1.00
180_H	184_Q	0.560	1.00
125_L	130_E	0.559	1.00
38_L	70_I	0.558	1.00
11_G	38_L	0.558	1.00
295_A	298_F	0.556	1.00
196_F	199_A	0.554	1.00
124_R	130_E	0.554	1.00
23_G	28_K	0.553	1.00
113_I	251_I	0.552	1.00
299_A	303_I	0.551	1.00
270_E	273_L	0.550	1.00
123_S	242_I	0.546	1.00
300_H	304_A	0.546	1.00
248_L	258_M	0.546	1.00
167_L	172_V	0.542	1.00
166_A	201_V	0.541	1.00
166_A	176_V	0.540	1.00
59_G	62_A	0.538	1.00
154_L	177_T	0.538	1.00
35_Q	42_L	0.537	1.00
153_V	239_I	0.537	1.00
68_R	72_Q	0.535	1.00
155_I	162_A	0.534	1.00
254_W	258_M	0.534	1.00
115_A	250_N	0.533	1.00
147_D	150_G	0.532	1.00
197_R	202_Y	0.532	1.00
23_G	79_D	0.529	1.00
8_V	29_T	0.529	1.00
165_W	241_S	0.527	1.00
122_P	125_L	0.527	1.00
87_D	91_K	0.526	1.00
148_F	237_S	0.525	1.00
137_G	143_R	0.525	1.00
31_L	80_I	0.522	1.00
152_R	233_L	0.522	1.00
138_V	141_T	0.520	1.00
178_L	203_V	0.516	1.00
262_D	292_A	0.516	1.00
307_V	310_K	0.515	1.00
63_Y	66_A	0.515	1.00
83_N	87_D	0.514	1.00
179_I	235_V	0.509	1.00
60_I	64_E	0.508	1.00
108_T	275_G	0.507	1.00
21_Y	305_I	0.505	1.00
162_A	241_S	0.505	1.00
97_W	276_V	0.504	1.00
294_I	297_G	0.504	1.00
113_I	276_V	0.504	1.00
256_V	273_L	0.503	1.00
260_G	284_Q	0.502	1.00
295_A	299_A	0.500	1.00
86_A	89_I	0.500	1.00

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3lzwA	2	0.9729	100	0.277	Contact Map
3ab1A	2	0.988	100	0.287	Contact Map
2zbwA	2	0.9789	100	0.3	Contact Map
2q0lA	2	0.9096	100	0.3	Contact Map
1vdcA	2	0.9127	100	0.309	Contact Map
4up3A	2	0.9036	100	0.309	Contact Map
2q7vA	2	0.9096	100	0.314	Contact Map
3f8dA	2	0.9096	100	0.316	Contact Map
4c5oA	5	0.8795	100	0.318	Contact Map
1trbA	2	0.9096	100	0.318	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0103 seconds.