GREMLIN Database
DTDA - D-aminoacyl-tRNA deacylase
UniProt: Q97WI2 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 238 (222)
Sequences: 245 (181)
Seq/√Len: 12.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
45_F142_T5.7661.00
13_V16_T4.1981.00
99_I131_N3.2890.98
44_I117_V3.2110.97
11_D14_G3.0570.96
7_Y18_K2.7510.93
8_S14_G2.5660.90
89_L175_D2.5100.89
8_S11_D2.4890.89
12_P18_K2.4370.88
198_Q202_N2.2650.84
75_K192_D2.2310.83
13_V17_I2.2150.82
88_I92_I2.2120.82
7_Y14_G2.1730.81
183_I191_L2.1400.80
13_V18_K2.1350.80
122_V134_I2.1150.79
86_T90_R2.1010.79
89_L103_M2.0990.79
193_D229_K2.0780.78
79_I202_N2.0580.77
124_S129_W2.0520.77
160_G170_F2.0510.77
11_D16_T1.9770.74
106_T181_H1.9100.72
77_L198_Q1.8950.71
8_S13_V1.8920.71
64_N72_G1.8830.71
103_M174_A1.8690.70
78_G117_V1.8170.68
52_A56_S1.8110.67
213_D216_N1.8090.67
146_I161_F1.7860.66
61_Y85_L1.7820.66
73_E76_K1.7820.66
137_A225_A1.7660.65
47_R55_P1.7610.65
102_T174_A1.7600.65
11_D18_K1.7200.63
217_S220_K1.7150.63
71_G109_G1.6670.61
159_S200_I1.6640.61
15_V18_K1.6330.59
44_I178_C1.6270.59
95_I140_D1.6140.58
85_L103_M1.6040.58
14_G18_K1.5930.57
86_T174_A1.5910.57
164_P207_I1.5780.56
41_A84_L1.5680.56
27_I142_T1.5330.54
81_Y118_I1.5310.54
88_I120_V1.5120.53
55_P124_S1.5090.53
62_P111_T1.5030.53
47_R76_K1.4470.50
14_G17_I1.4440.50
220_K224_I1.4360.49
62_P117_V1.4350.49
125_N128_Y1.4150.48
158_I179_I1.3930.47
101_K187_Y1.3860.47
212_I215_L1.3830.47
77_L171_T1.3700.46
27_I30_D1.3550.45
171_T175_D1.3510.45
109_G116_P1.3260.44
169_L216_N1.3230.44
181_H199_T1.3210.43
64_N71_G1.3070.43
25_E28_N1.3040.43
27_I44_I1.2990.42
224_I227_L1.2910.42
16_T135_V1.2830.42
54_I100_E1.2730.41
176_E203_S1.2680.41
180_G207_I1.2640.41
21_G119_F1.2630.41
163_G213_D1.2450.40
76_K112_Y1.2410.39
220_K228_K1.2300.39
65_P74_P1.2270.39
52_A103_M1.2260.39
69_I74_P1.2210.39
210_V227_L1.2090.38
57_L126_E1.1950.37
59_V85_L1.1920.37
10_L14_G1.1750.36
172_K176_E1.1690.36
45_F103_M1.1640.36
70_M76_K1.1590.36
44_I119_F1.1200.34
183_I199_T1.1190.34
169_L211_V1.1190.34
76_K198_Q1.1160.34
172_K208_N1.1040.33
46_S166_Y1.0980.33
62_P195_V1.0980.33
31_V44_I1.0960.33
22_Y27_I1.0950.33
128_Y188_I1.0630.31
65_P199_T1.0630.31
221_E224_I1.0620.31
21_G25_E1.0590.31
15_V19_K1.0550.31
105_A167_S1.0530.31
22_Y29_E1.0530.31
154_C201_T1.0380.30
223_I227_L1.0370.30
48_H123_G1.0260.30
196_I226_S1.0200.29
47_R57_L1.0110.29
128_Y182_V1.0070.29
62_P78_G1.0030.29
71_G116_P0.9920.28
44_I138_L0.9800.28
89_L174_A0.9780.28
164_P187_Y0.9780.28
55_P207_I0.9770.28
51_K122_V0.9670.27
27_I32_T0.9650.27
7_Y17_I0.9580.27
223_I228_K0.9420.26
59_V174_A0.9190.25
161_F219_Q0.8890.24
40_E130_T0.8790.24
101_K164_P0.8770.24
30_D33_D0.8750.24
80_A99_I0.8680.23
196_I199_T0.8660.23
32_T36_Y0.8620.23
50_S163_G0.8610.23
115_V167_S0.8580.23
209_K212_I0.8500.23
15_V159_S0.8440.23
174_A217_S0.8420.23
169_L212_I0.8350.22
77_L80_A0.8320.22
42_I174_A0.8280.22
184_S187_Y0.8270.22
53_G189_D0.8250.22
59_V103_M0.8240.22
58_T82_P0.8210.22
40_E51_K0.8170.22
12_P16_T0.8030.21
30_D134_I0.7910.21
58_T89_L0.7880.21
55_P158_I0.7820.20
106_T109_G0.7770.20
40_E187_Y0.7770.20
7_Y16_T0.7760.20
115_V174_A0.7730.20
77_L202_N0.7710.20
44_I214_S0.7710.20
82_P109_G0.7660.20
92_I138_L0.7630.20
40_E94_K0.7600.20
54_I91_E0.7580.20
55_P128_Y0.7530.20
55_P213_D0.7510.19
53_G125_N0.7490.19
140_D227_L0.7470.19
22_Y32_T0.7470.19
65_P183_I0.7450.19
45_F65_P0.7420.19
21_G24_F0.7410.19
179_I213_D0.7400.19
74_P224_I0.7340.19
180_G208_N0.7290.19
131_N145_S0.7270.19
151_E155_E0.7220.19
102_T180_G0.7180.18
91_E94_K0.7170.18
41_A81_Y0.7160.18
90_R172_K0.7150.18
67_E102_T0.7100.18
30_D36_Y0.7100.18
44_I134_I0.7090.18
22_Y68_E0.7070.18
120_V132_D0.7060.18
104_E108_H0.7050.18
110_P121_E0.7050.18
108_H121_E0.7050.18
107_H121_E0.7050.18
60_H110_P0.7050.18
60_H108_H0.7050.18
60_H107_H0.7050.18
107_H110_P0.7050.18
60_H63_G0.7050.18
60_H121_E0.7050.18
60_H104_E0.7050.18
104_E121_E0.7050.18
104_E110_P0.7050.18
104_E107_H0.7050.18
63_G104_E0.7050.18
63_G107_H0.7050.18
63_G110_P0.7050.18
63_G108_H0.7050.18
63_G121_E0.7050.18
207_I211_V0.7050.18
67_E187_Y0.7020.18
73_E127_T0.6960.18
131_N137_A0.6950.18
11_D17_I0.6940.18
24_F30_D0.6910.18
120_V128_Y0.6860.18
7_Y21_G0.6840.17
136_K140_D0.6820.17
64_N111_T0.6780.17
72_G109_G0.6760.17
10_L105_A0.6740.17
158_I210_V0.6710.17
78_G112_Y0.6680.17
27_I39_G0.6650.17
75_K202_N0.6630.17
90_R194_K0.6630.17
86_T103_M0.6620.17
124_S173_L0.6600.17
186_H215_L0.6530.17
38_N51_K0.6520.17
163_G168_R0.6440.16
71_G123_G0.6400.16
52_A170_F0.6390.16
125_N147_D0.6360.16
47_R193_D0.6360.16
103_M188_I0.6340.16
200_I219_Q0.6330.16
119_F220_K0.6320.16
155_E216_N0.6310.16
136_K228_K0.6300.16
64_N109_G0.6280.16
14_G164_P0.6270.16
89_L101_K0.6270.16
107_H162_G0.6240.16
110_P162_G0.6240.16
121_E162_G0.6240.16
108_H162_G0.6240.16
60_H162_G0.6240.16
63_G162_G0.6240.16
104_E162_G0.6240.16
141_S190_K0.6240.16
88_I118_I0.6240.16
55_P119_F0.6210.16
47_R202_N0.6190.16
135_V142_T0.6170.16
72_G123_G0.6160.16
139_V160_G0.6110.15
22_Y37_E0.6110.15
124_S169_L0.6110.15
169_L209_K0.6110.15
105_A185_K0.6070.15
92_I196_I0.6070.15
219_Q222_R0.6060.15
62_P211_V0.6060.15
115_V120_V0.6060.15
184_S214_S0.6030.15
56_S195_V0.6020.15
67_E89_L0.6020.15
43_V140_D0.6020.15
58_T103_M0.6010.15
12_P15_V0.5940.15
145_S179_I0.5930.15
24_F27_I0.5920.15
76_K173_L0.5900.15
122_V155_E0.5900.15
217_S221_E0.5870.15
160_G164_P0.5860.15
89_L169_L0.5860.15
47_R92_I0.5850.15
211_V216_N0.5840.15
199_T203_S0.5830.15
94_K201_T0.5820.15
75_K191_L0.5820.15
198_Q201_T0.5800.15
173_L221_E0.5790.15
186_H198_Q0.5780.15
185_K211_V0.5750.14
114_N141_S0.5730.14
65_P102_T0.5730.14
25_E157_Y0.5720.14
128_Y198_Q0.5680.14
84_L88_I0.5670.14
218_K222_R0.5660.14
28_N174_A0.5640.14
21_G28_N0.5630.14
174_A179_I0.5630.14
102_T196_I0.5620.14
43_V67_E0.5570.14
81_Y115_V0.5560.14
123_G129_W0.5540.14
217_S226_S0.5520.14
56_S202_N0.5520.14
74_P173_L0.5490.14
82_P203_S0.5450.14
56_S59_V0.5420.14
6_V203_S0.5400.14
45_F122_V0.5370.14
12_P125_N0.5370.14
43_V90_R0.5360.14
43_V93_K0.5290.13
196_I215_L0.5280.13
85_L171_T0.5260.13
43_V217_S0.5250.13
48_H129_W0.5250.13
67_E113_Q0.5250.13
52_A164_P0.5240.13
94_K225_A0.5230.13
95_I144_R0.5230.13
57_L160_G0.5180.13
106_T223_I0.5160.13
158_I187_Y0.5150.13
167_S170_F0.5140.13
178_C207_I0.5130.13
44_I168_R0.5130.13
159_S195_V0.5120.13
19_K176_E0.5110.13
159_S197_I0.5100.13
18_K32_T0.5090.13
29_E117_V0.5080.13
38_N221_E0.5080.13
197_I223_I0.5060.13
12_P19_K0.5050.13
80_A101_K0.5050.13
9_T19_K0.5040.13
40_E229_K0.5040.13
77_L131_N0.5040.13
217_S228_K0.5030.13
55_P125_N0.5020.13
74_P209_K0.5010.13
89_L171_T0.5010.13
85_L118_I0.5000.13
105_A184_S0.5000.13
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2gfqA 3 0.9916 100 0.149 Contact Map
1yqeA 1 0.979 100 0.155 Contact Map
3qayA 1 0.521 83 0.948 Contact Map
2x0dA 2 0.4748 69.7 0.954 Contact Map
4lq6A 1 0.5546 67 0.955 Contact Map
3ot5A 2 0.5672 64.5 0.956 Contact Map
1v4vA 2 0.563 59.7 0.957 Contact Map
4rn7A 1 0.5126 57.3 0.957 Contact Map
1jwqA 1 0.5084 55.5 0.958 Contact Map
2ywbA 4 0.7689 53.2 0.958 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0084 seconds.