RAD50 - SULSO - GREMLIN Contacts

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RAD50 - DNA double-strand break repair Rad50 ATPase

UniProt:	Q97WH0	Sequences: MRIDKITLTNFLSHEHSEIQFMGEINVIVGQNGAGKSSIIDGIVFSLFRTHSRGNNDNLIRKGSNRGSVTLYLSNEKDKIEIIRDIRSTTEDRLIRNQFPIARSATVVSNEIEKILGIDKDIALSTIIVRQGELDKILENFQEIMGKILKLELIEKLIDSRGPIVEFRKNLENKLRELDRIEQDYNNFKKTVEEKRARVLELKKDKEKLEDEIKNLEKRIKDIKDQFDEYEKKRNQYLKLTTTLKIKEGELNELNRSIEELRKQTENMDQLEKEINELENLRNIKLKFEKYEVLAKSHTEMSANVINLEKEIEEYEKAIRRKEELEPKYLKYKELERKLEELQPKYQQYLKLKSDLDSKLNLKERLEKDASELSNDIDKVNSLEQKVEETRKKQLNLRAQLAKVESLISEKNEIINNISQVEGETCPVCGRPLDEEHKQKIIKEAKSYILQLELNKNELEEELKKITNELNKIEREYRRLSNNKASYDNVMRQLKKLNEEIENLHSEIESLKNIDEEIKKINEEVKELKLYYEEFMRLSKYTKEELDKKRVKLDEMKKKKEEIEKEMRGLESELKGLDRKALESKILDLENKRVKLDEMKKKKGILEDYIRQVKLLQEEVKNLREEVNIIQFDENRYNELKTSLDAYNLSLKEKENRKSRIEGELESLEKDIEEISNRIANYELQLKDREKIINAINKLEKIRSALGERKLQSYIIMTTKQLIENNLNDIISKFDLSIKNVEMEIMPKTGRGRSSSGDILVYTNSGDTLPIVSLSGGERIALSIALRLAIAKALMSNTNFFILDEPTIHLDDQRKAYLIEIIRAAKESVPQIIVVTHDEEVVQAADYVIRVEKRGNKSFVREET	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	864 (814)
Sequences:	6533 (6339)
Seq/√Len:	222.2

ECOLI - SBCC
BACSU - SBCC SMC YHAN
HALSA - RAD50 Q9HS95 SPH1 SPH2
SULSO - RAD50

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
5_K	18_E	3.005	1.00
7_T	18_E	2.843	1.00
496_K	500_E	2.782	1.00
7_T	70_T	2.534	1.00
448_Y	451_Q	2.395	1.00
733_K	824_A	2.382	1.00
311_E	315_Y	2.371	1.00
456_K	460_E	2.305	1.00
111_E	114_K	2.274	1.00
414_I	417_N	2.228	1.00
396_N	400_Q	2.215	1.00
603_K	607_E	2.206	1.00
61_R	64_S	2.204	1.00
608_D	612_Q	2.196	1.00
691_K	695_A	2.173	1.00
84_R	92_D	2.169	1.00
568_R	571_E	2.163	1.00
311_E	314_E	2.146	1.00
534_E	538_L	2.139	1.00
60_I	64_S	2.131	1.00
70_T	83_I	2.125	1.00
517_E	520_K	2.099	1.00
560_K	564_E	2.096	1.00
446_K	450_L	2.077	1.00
206_K	210_E	2.072	1.00
412_N	416_N	2.063	1.00
236_Q	239_K	2.061	1.00
545_E	548_K	2.047	1.00
331_K	334_E	2.041	1.00
313_E	316_E	2.006	1.00
590_E	594_V	1.978	1.00
334_E	338_K	1.976	1.00
291_Y	295_A	1.972	1.00
669_E	673_E	1.964	1.00
287_K	290_K	1.953	1.00
239_K	243_T	1.935	1.00
246_I	250_E	1.932	1.00
332_Y	336_E	1.921	1.00
372_E	375_N	1.919	1.00
336_E	340_E	1.916	1.00
335_L	339_L	1.915	1.00
345_K	349_Y	1.904	1.00
416_N	420_Q	1.897	1.00
585_K	588_D	1.897	1.00
532_Y	536_M	1.890	1.00
417_N	420_Q	1.889	1.00
269_D	272_E	1.884	1.00
543_K	547_D	1.863	1.00
271_L	275_I	1.856	1.00
384_E	388_E	1.847	1.00
259_E	262_R	1.845	1.00
449_I	453_E	1.839	1.00
665_L	669_E	1.835	1.00
389_E	393_K	1.835	1.00
498_N	502_E	1.827	1.00
4_D	74_S	1.825	1.00
564_E	568_R	1.823	1.00
195_K	198_R	1.820	1.00
455_N	458_E	1.812	1.00
453_E	457_N	1.804	1.00
298_H	302_S	1.803	1.00
90_T	94_L	1.800	1.00
555_E	559_K	1.799	1.00
702_I	708_E	1.794	1.00
260_E	264_Q	1.787	1.00
309_E	313_E	1.785	1.00
457_N	460_E	1.783	1.00
565_K	569_G	1.782	1.00
356_L	360_L	1.782	1.00
693_I	697_N	1.776	1.00
407_L	410_E	1.763	1.00
243_T	246_I	1.757	1.00
382_S	386_K	1.751	1.00
471_N	474_E	1.749	1.00
173_N	176_R	1.747	1.00
566_E	570_L	1.745	1.00
451_Q	455_N	1.731	1.00
703_R	707_G	1.731	1.00
162_G	165_V	1.727	1.00
653_E	657_R	1.726	1.00
295_A	299_T	1.725	1.00
9_T	68_S	1.722	1.00
304_N	308_L	1.722	1.00
355_D	359_K	1.719	1.00
5_K	72_Y	1.718	1.00
340_E	343_Q	1.712	1.00
193_E	196_R	1.707	1.00
314_E	318_A	1.707	1.00
522_N	526_K	1.700	1.00
400_Q	404_V	1.696	1.00
606_L	610_I	1.696	1.00
255_N	259_E	1.694	1.00
305_V	309_E	1.691	1.00
411_K	415_I	1.688	1.00
367_E	371_S	1.681	1.00
341_E	345_K	1.675	1.00
620_V	624_R	1.672	1.00
619_E	622_N	1.671	1.00
524_E	528_L	1.669	1.00
270_Q	274_E	1.667	1.00
470_L	474_E	1.666	1.00
248_E	252_N	1.662	1.00
390_T	394_Q	1.660	1.00
254_L	257_S	1.650	1.00
467_T	471_N	1.647	1.00
184_D	187_N	1.645	1.00
617_Q	621_K	1.643	1.00
253_E	257_S	1.642	1.00
474_E	478_R	1.642	1.00
519_K	522_N	1.641	1.00
256_R	260_E	1.627	1.00
352_L	355_D	1.621	1.00
247_K	250_E	1.618	1.00
527_E	531_Y	1.617	1.00
447_S	451_Q	1.616	1.00
60_I	63_G	1.614	1.00
402_A	405_E	1.613	1.00
4_D	79_K	1.612	1.00
553_L	557_K	1.611	1.00
668_L	672_I	1.611	1.00
316_E	320_R	1.608	1.00
413_E	420_Q	1.603	1.00
269_D	273_K	1.603	1.00
548_K	552_K	1.599	1.00
344_P	348_Q	1.582	1.00
531_Y	534_E	1.581	1.00
538_L	542_T	1.577	1.00
407_L	411_K	1.573	1.00
468_N	472_K	1.572	1.00
625_E	629_I	1.571	1.00
133_E	136_K	1.568	1.00
613_V	616_L	1.567	1.00
469_E	472_K	1.566	1.00
562_E	566_E	1.564	1.00
469_E	473_I	1.563	1.00
207_E	210_E	1.563	1.00
610_I	614_K	1.562	1.00
276_N	279_E	1.560	1.00
290_K	293_V	1.559	1.00
513_N	517_E	1.559	1.00
695_A	698_K	1.552	1.00
394_Q	398_R	1.552	1.00
371_S	375_N	1.550	1.00
397_L	401_L	1.549	1.00
3_I	71_L	1.547	1.00
519_K	523_E	1.543	1.00
92_D	96_R	1.540	1.00
405_E	409_S	1.539	1.00
342_L	346_Y	1.526	1.00
445_A	449_I	1.525	1.00
590_E	593_R	1.523	1.00
626_E	629_I	1.522	1.00
463_L	467_T	1.521	1.00
571_E	575_K	1.521	1.00
523_E	527_E	1.519	1.00
547_D	550_R	1.514	1.00
205_D	208_K	1.513	1.00
573_E	577_L	1.505	1.00
386_K	389_E	1.499	1.00
408_I	412_N	1.494	1.00
700_E	704_S	1.490	1.00
233_K	236_Q	1.490	1.00
272_E	276_N	1.489	1.00
221_K	224_K	1.488	1.00
545_E	549_K	1.487	1.00
524_E	527_E	1.484	1.00
614_K	617_Q	1.483	1.00
686_L	689_R	1.480	1.00
274_E	277_E	1.478	1.00
337_R	341_E	1.478	1.00
365_R	368_K	1.463	1.00
290_K	294_L	1.461	1.00
242_T	245_K	1.453	1.00
781_A	814_R	1.449	1.00
601_K	605_I	1.448	1.00
88_S	92_D	1.446	1.00
404_V	408_I	1.445	1.00
308_L	312_I	1.443	1.00
240_L	244_L	1.443	1.00
667_S	671_D	1.441	1.00
587_L	590_E	1.440	1.00
353_K	357_D	1.438	1.00
347_Q	350_L	1.432	1.00
613_V	617_Q	1.431	1.00
622_N	626_E	1.431	1.00
497_L	501_I	1.427	1.00
362_L	365_R	1.426	1.00
257_S	260_E	1.426	1.00
338_K	341_E	1.425	1.00
373_L	377_I	1.425	1.00
526_K	529_K	1.424	1.00
252_N	255_N	1.422	1.00
307_N	311_E	1.421	1.00
600_K	604_G	1.421	1.00
400_Q	403_K	1.420	1.00
466_I	469_E	1.418	1.00
292_E	295_A	1.417	1.00
381_N	384_E	1.412	1.00
636_R	639_E	1.411	1.00
834_V	841_V	1.407	1.00
541_Y	545_E	1.402	1.00
624_R	628_N	1.401	1.00
315_Y	318_A	1.401	1.00
345_K	348_Q	1.399	1.00
386_K	390_T	1.399	1.00
409_S	412_N	1.398	1.00
398_R	402_A	1.395	1.00
472_K	476_E	1.393	1.00
583_E	587_L	1.391	1.00
297_S	301_M	1.390	1.00
84_R	90_T	1.386	1.00
367_E	370_A	1.386	1.00
244_L	248_E	1.386	1.00
333_K	336_E	1.385	1.00
416_N	419_S	1.385	1.00
317_K	321_R	1.379	1.00
529_K	533_E	1.378	1.00
379_K	382_S	1.376	1.00
502_E	505_H	1.373	1.00
224_K	228_D	1.373	1.00
300_E	304_N	1.372	1.00
546_L	550_R	1.371	1.00
554_D	558_K	1.369	1.00
12_L	38_S	1.369	1.00
380_V	384_E	1.367	1.00
549_K	552_K	1.366	1.00
464_K	468_N	1.366	1.00
385_Q	389_E	1.363	1.00
328_K	331_K	1.363	1.00
651_L	655_E	1.362	1.00
452_L	456_K	1.358	1.00
567_M	571_E	1.357	1.00
505_H	509_E	1.357	1.00
302_S	306_I	1.357	1.00
569_G	573_E	1.357	1.00
438_K	442_I	1.356	1.00
776_G	805_E	1.356	1.00
401_L	405_E	1.353	1.00
414_I	418_I	1.350	1.00
611_R	615_L	1.349	1.00
315_Y	319_I	1.346	1.00
374_S	377_I	1.343	1.00
310_K	314_E	1.343	1.00
686_L	690_E	1.343	1.00
735_D	739_K	1.340	1.00
351_K	355_D	1.340	1.00
600_K	603_K	1.338	1.00
690_E	694_N	1.338	1.00
168_R	172_E	1.330	1.00
222_D	226_Q	1.330	1.00
391_R	395_L	1.328	1.00
250_E	253_E	1.327	1.00
293_V	297_S	1.325	1.00
343_Q	347_Q	1.325	1.00
413_E	417_N	1.321	1.00
273_K	277_E	1.320	1.00
607_E	611_R	1.319	1.00
296_K	299_T	1.318	1.00
232_K	236_Q	1.317	1.00
665_L	668_L	1.316	1.00
297_S	300_E	1.315	1.00
287_K	291_Y	1.315	1.00
535_F	538_L	1.309	1.00
751_R	754_S	1.308	1.00
654_K	657_R	1.307	1.00
198_R	201_E	1.305	1.00
342_L	345_K	1.305	1.00
417_N	421_V	1.304	1.00
8_L	39_I	1.304	1.00
375_N	379_K	1.303	1.00
504_L	508_I	1.302	1.00
599_M	603_K	1.301	1.00
381_N	385_Q	1.300	1.00
361_N	365_R	1.299	1.00
393_K	396_N	1.298	1.00
249_G	253_E	1.291	1.00
368_K	372_E	1.285	1.00
637_Y	641_K	1.285	1.00
607_E	610_I	1.282	1.00
661_I	665_L	1.281	1.00
160_S	163_P	1.281	1.00
327_P	331_K	1.275	1.00
685_Q	688_D	1.275	1.00
615_L	619_E	1.273	1.00
612_Q	615_L	1.272	1.00
533_E	536_M	1.272	1.00
335_L	338_K	1.270	1.00
462_E	465_K	1.268	1.00
326_E	329_Y	1.266	1.00
539_S	543_K	1.264	1.00
191_T	195_K	1.260	1.00
262_R	266_E	1.259	1.00
780_I	809_H	1.258	1.00
70_T	81_E	1.254	1.00
370_A	374_S	1.254	1.00
573_E	576_G	1.254	1.00
476_E	479_R	1.253	1.00
623_L	626_E	1.253	1.00
455_N	459_L	1.251	1.00
312_I	315_Y	1.249	1.00
518_I	522_N	1.246	1.00
214_K	217_E	1.240	1.00
520_K	524_E	1.239	1.00
552_K	556_M	1.238	1.00
324_E	328_K	1.237	1.00
491_M	495_K	1.236	1.00
540_K	543_K	1.230	1.00
648_N	652_K	1.227	1.00
226_Q	229_E	1.224	1.00
635_N	638_N	1.224	1.00
348_Q	352_L	1.224	1.00
724_E	728_N	1.222	1.00
395_L	399_A	1.220	1.00
192_V	196_R	1.219	1.00
387_V	391_R	1.215	1.00
552_K	555_E	1.215	1.00
235_N	239_K	1.214	1.00
306_I	309_E	1.209	1.00
223_I	227_F	1.208	1.00
383_L	387_V	1.208	1.00
515_D	519_K	1.208	1.00
245_K	249_G	1.206	1.00
448_Y	452_L	1.206	1.00
197_A	201_E	1.205	1.00
271_L	274_E	1.204	1.00
616_L	620_V	1.204	1.00
212_E	215_N	1.203	1.00
60_I	67_G	1.202	1.00
159_D	162_G	1.201	1.00
697_N	701_K	1.200	1.00
741_V	745_I	1.199	1.00
737_S	741_V	1.199	1.00
208_K	212_E	1.198	1.00
606_L	609_Y	1.197	1.00
605_I	608_D	1.197	1.00
216_L	220_I	1.195	1.00
726_N	792_K	1.195	1.00
672_I	675_I	1.193	1.00
450_L	453_E	1.190	1.00
181_I	188_F	1.190	1.00
294_L	298_H	1.189	1.00
558_K	562_E	1.189	1.00
464_K	467_T	1.187	1.00
410_E	414_I	1.187	1.00
494_L	498_N	1.187	1.00
666_E	670_K	1.186	1.00
358_S	361_N	1.185	1.00
240_L	243_T	1.184	1.00
621_K	624_R	1.184	1.00
701_K	705_A	1.183	1.00
245_K	248_E	1.182	1.00
503_N	507_E	1.180	1.00
304_N	307_N	1.179	1.00
588_D	592_K	1.178	1.00
264_Q	267_N	1.178	1.00
444_E	448_Y	1.178	1.00
6_I	21_F	1.174	1.00
365_R	369_D	1.172	1.00
557_K	561_E	1.171	1.00
493_Q	496_K	1.170	1.00
643_S	646_A	1.170	1.00
104_S	107_V	1.168	1.00
666_E	669_E	1.167	1.00
575_K	578_D	1.166	1.00
537_R	540_K	1.166	1.00
338_K	342_L	1.165	1.00
566_E	569_G	1.164	1.00
234_R	238_L	1.162	1.00
554_D	557_K	1.161	1.00
362_L	366_L	1.160	1.00
301_M	305_V	1.160	1.00
702_I	705_A	1.156	1.00
286_L	290_K	1.155	1.00
316_E	319_I	1.155	1.00
517_E	521_I	1.154	1.00
136_K	140_N	1.154	1.00
550_R	554_D	1.152	1.00
186_N	189_K	1.151	1.00
403_K	407_L	1.150	1.00
247_K	251_L	1.150	1.00
559_K	562_E	1.148	1.00
11_F	45_F	1.146	1.00
225_D	228_D	1.145	1.00
192_V	195_K	1.145	1.00
581_A	585_K	1.144	1.00
660_R	664_E	1.144	1.00
33_G	778_E	1.143	1.00
447_S	450_L	1.142	1.00
645_D	648_N	1.141	1.00
318_A	321_R	1.140	1.00
328_K	332_Y	1.139	1.00
650_S	653_E	1.134	1.00
46_S	71_L	1.134	1.00
223_I	226_Q	1.133	1.00
484_K	488_D	1.133	1.00
695_A	702_I	1.132	1.00
165_V	168_R	1.129	1.00
251_L	255_N	1.128	1.00
644_L	648_N	1.128	1.00
443_K	447_S	1.127	1.00
220_I	224_K	1.122	1.00
778_E	805_E	1.121	1.00
388_E	391_R	1.119	1.00
591_N	595_K	1.119	1.00
330_L	334_E	1.118	1.00
741_V	744_E	1.117	1.00
321_R	324_E	1.114	1.00
623_L	627_V	1.114	1.00
262_R	265_T	1.113	1.00
742_E	760_L	1.112	1.00
402_A	406_S	1.112	1.00
475_R	479_R	1.112	1.00
739_K	743_M	1.110	1.00
349_Y	352_L	1.109	1.00
222_D	225_D	1.108	1.00
299_T	302_S	1.106	1.00
82_I	112_I	1.103	1.00
670_K	674_E	1.103	1.00
538_L	541_Y	1.101	1.00
533_E	537_R	1.099	1.00
298_H	301_M	1.097	1.00
568_R	572_S	1.097	1.00
270_Q	273_K	1.096	1.00
544_E	548_K	1.095	1.00
261_L	264_Q	1.095	1.00
618_E	621_K	1.095	1.00
213_I	217_E	1.093	1.00
203_K	207_E	1.090	1.00
182_E	186_N	1.089	1.00
704_S	708_E	1.088	1.00
595_K	598_E	1.086	1.00
376_D	380_V	1.085	1.00
547_D	551_V	1.085	1.00
258_I	262_R	1.084	1.00
189_K	193_E	1.083	1.00
415_I	418_I	1.082	1.00
163_P	166_E	1.081	1.00
68_S	85_D	1.081	1.00
780_I	807_T	1.080	1.00
238_L	241_T	1.077	1.00
72_Y	81_E	1.075	1.00
346_Y	350_L	1.074	1.00
643_S	647_Y	1.073	1.00
331_K	335_L	1.072	1.00
303_A	306_I	1.072	1.00
586_I	590_E	1.070	1.00
549_K	553_L	1.070	1.00
216_L	219_R	1.070	1.00
650_S	654_K	1.069	1.00
530_L	533_E	1.068	1.00
809_H	841_V	1.068	1.00
450_L	454_L	1.066	1.00
761_V	782_L	1.065	1.00
363_K	367_E	1.064	1.00
494_L	497_L	1.063	1.00
482_N	486_S	1.061	1.00
499_E	503_N	1.060	1.00
696_I	700_E	1.059	1.00
329_Y	333_K	1.058	1.00
242_T	246_I	1.058	1.00
635_N	639_E	1.057	1.00
527_E	530_L	1.053	1.00
466_I	470_L	1.053	1.00
250_E	254_L	1.052	1.00
43_I	47_L	1.051	1.00
366_L	370_A	1.045	1.00
354_S	357_D	1.045	1.00
556_M	559_K	1.045	1.00
257_S	261_L	1.042	1.00
364_E	367_E	1.042	1.00
225_D	229_E	1.041	1.00
493_Q	497_L	1.034	1.00
289_E	293_V	1.034	1.00
653_E	656_N	1.033	1.00
495_K	498_N	1.033	1.00
218_K	222_D	1.031	1.00
616_L	619_E	1.030	1.00
471_N	475_R	1.030	1.00
67_G	86_I	1.028	1.00
602_K	605_I	1.027	1.00
470_L	473_I	1.025	1.00
219_R	222_D	1.025	1.00
112_I	115_I	1.024	1.00
620_V	623_L	1.022	1.00
521_I	525_V	1.022	1.00
780_I	806_P	1.021	1.00
664_E	667_S	1.021	1.00
180_R	183_Q	1.020	1.00
516_E	520_K	1.020	1.00
659_S	662_E	1.020	1.00
604_G	608_D	1.019	1.00
556_M	560_K	1.019	1.00
678_R	682_Y	1.018	1.00
584_S	588_D	1.017	1.00
169_K	172_E	1.017	1.00
502_E	506_S	1.017	1.00
346_Y	349_Y	1.016	1.00
349_Y	353_K	1.013	1.00
352_L	356_L	1.012	1.00
636_R	640_L	1.011	1.00
8_L	42_G	1.011	1.00
43_I	71_L	1.010	1.00
278_L	283_N	1.009	1.00
678_R	681_N	1.008	1.00
611_R	614_K	1.007	1.00
680_A	683_E	1.004	1.00
454_L	458_E	1.002	1.00
691_K	698_K	1.001	1.00
531_Y	535_F	1.001	1.00
468_N	471_N	0.997	1.00
806_P	838_D	0.995	1.00
780_I	808_I	0.994	1.00
663_G	667_S	0.994	1.00
73_L	80_I	0.994	1.00
673_E	677_N	0.993	1.00
339_L	343_Q	0.992	1.00
394_Q	397_L	0.991	1.00
293_V	296_K	0.991	1.00
477_Y	481_S	0.991	1.00
285_K	288_F	0.988	1.00
716_I	720_K	0.988	1.00
355_D	358_S	0.987	1.00
500_E	503_N	0.984	1.00
483_N	486_S	0.983	1.00
212_E	216_L	0.983	1.00
406_S	410_E	0.983	1.00
204_K	208_K	0.982	1.00
215_N	219_R	0.982	1.00
703_R	706_L	0.980	1.00
439_Q	443_K	0.979	1.00
812_D	839_E	0.977	1.00
528_L	531_Y	0.977	1.00
787_R	807_T	0.977	1.00
592_K	596_L	0.975	1.00
514_I	518_I	0.975	1.00
726_N	729_D	0.974	1.00
803_L	822_I	0.973	1.00
711_L	715_I	0.971	1.00
56_N	60_I	0.971	1.00
203_K	206_K	0.967	1.00
110_N	113_E	0.964	1.00
72_Y	79_K	0.964	1.00
574_L	578_D	0.964	1.00
399_A	402_A	0.963	1.00
390_T	393_K	0.963	1.00
625_E	628_N	0.963	1.00
254_L	258_I	0.960	1.00
639_E	643_S	0.960	1.00
369_D	372_E	0.960	1.00
530_L	534_E	0.959	1.00
217_E	221_K	0.957	1.00
413_E	416_N	0.957	1.00
442_I	446_K	0.956	1.00
609_Y	613_V	0.956	1.00
671_D	674_E	0.954	1.00
58_N	62_K	0.952	1.00
735_D	741_V	0.951	1.00
243_T	247_K	0.950	1.00
805_E	835_V	0.950	1.00
525_V	529_K	0.949	1.00
129_V	137_I	0.949	1.00
592_K	595_K	0.949	1.00
619_E	623_L	0.948	1.00
737_S	743_M	0.948	1.00
241_T	245_K	0.946	1.00
313_E	317_K	0.946	1.00
180_R	184_D	0.946	1.00
109_S	112_I	0.943	1.00
89_T	94_L	0.943	1.00
45_F	69_V	0.942	1.00
561_E	564_E	0.942	1.00
305_V	308_L	0.942	1.00
68_S	83_I	0.939	1.00
415_I	419_S	0.939	1.00
536_M	540_K	0.938	1.00
377_I	381_N	0.937	1.00
329_Y	332_Y	0.936	1.00
393_K	397_L	0.935	1.00
668_L	671_D	0.934	1.00
570_L	573_E	0.932	1.00
685_Q	689_R	0.931	1.00
647_Y	651_L	0.931	1.00
807_T	838_D	0.929	1.00
559_K	563_I	0.929	1.00
372_E	376_D	0.929	1.00
641_K	645_D	0.928	1.00
84_R	88_S	0.927	1.00
528_L	532_Y	0.925	1.00
411_K	414_I	0.922	0.99
585_K	589_L	0.922	0.99
674_E	677_N	0.922	0.99
778_E	835_V	0.921	0.99
465_K	469_E	0.921	0.99
497_L	500_E	0.919	0.99
681_N	685_Q	0.918	0.99
294_L	297_S	0.917	0.99
816_A	820_E	0.917	0.99
739_K	744_E	0.917	0.99
621_K	625_E	0.916	0.99
232_K	235_N	0.914	0.99
166_E	169_K	0.913	0.99
244_L	247_K	0.913	0.99
288_F	292_E	0.911	0.99
780_I	837_H	0.906	0.99
177_E	180_R	0.903	0.99
614_K	618_E	0.903	0.99
167_F	170_N	0.902	0.99
369_D	373_L	0.900	0.99
383_L	386_K	0.898	0.99
90_T	96_R	0.898	0.99
48_F	123_A	0.898	0.99
695_A	706_L	0.898	0.99
674_E	678_R	0.897	0.99
714_Y	718_T	0.896	0.99
322_K	326_E	0.895	0.99
440_K	444_E	0.895	0.99
535_F	539_S	0.894	0.99
458_E	462_E	0.893	0.99
572_S	576_G	0.893	0.99
638_N	641_K	0.892	0.99
173_N	177_E	0.890	0.99
140_N	143_E	0.889	0.99
808_I	838_D	0.889	0.99
3_I	831_Q	0.888	0.99
176_R	179_D	0.886	0.99
454_L	457_N	0.885	0.99
683_E	687_K	0.885	0.99
252_N	256_R	0.885	0.99
308_L	311_E	0.885	0.99
334_E	337_R	0.884	0.99
3_I	43_I	0.881	0.99
682_Y	686_L	0.881	0.99
23_G	26_N	0.881	0.99
459_L	462_E	0.880	0.99
256_R	259_E	0.880	0.99
526_K	530_L	0.880	0.99
135_D	779_R	0.877	0.99
192_V	198_R	0.876	0.99
230_Y	234_R	0.875	0.99
459_L	463_L	0.875	0.99
663_G	666_E	0.873	0.99
237_Y	241_T	0.873	0.99
301_M	304_N	0.872	0.99
105_A	109_S	0.871	0.99
201_E	205_D	0.870	0.99
443_K	446_K	0.869	0.99
92_D	95_I	0.869	0.99
275_I	279_E	0.868	0.99
33_G	805_E	0.868	0.99
231_E	234_R	0.868	0.99
610_I	613_V	0.867	0.99
133_E	147_K	0.867	0.99
664_E	668_L	0.866	0.99
204_K	207_E	0.866	0.99
646_A	650_S	0.866	0.99
300_E	303_A	0.864	0.99
131_Q	776_G	0.863	0.99
306_I	310_K	0.861	0.99
730_I	792_K	0.861	0.99
525_V	532_Y	0.858	0.99
234_R	237_Y	0.858	0.99
473_I	477_Y	0.858	0.99
141_F	148_I	0.857	0.99
388_E	392_K	0.856	0.99
719_T	723_I	0.856	0.99
444_E	447_S	0.855	0.99
570_L	577_L	0.853	0.99
642_T	646_A	0.853	0.99
376_D	379_K	0.851	0.99
239_K	242_T	0.850	0.99
676_S	680_A	0.850	0.99
490_V	494_L	0.849	0.99
781_A	810_L	0.847	0.99
803_L	806_P	0.846	0.99
259_E	263_K	0.845	0.99
695_A	703_R	0.844	0.99
478_R	481_S	0.842	0.99
364_E	368_K	0.841	0.99
593_R	596_L	0.839	0.99
258_I	261_L	0.836	0.99
214_K	218_K	0.835	0.99
356_L	359_K	0.834	0.99
305_V	312_I	0.834	0.99
233_K	237_Y	0.834	0.99
602_K	606_L	0.833	0.99
646_A	649_L	0.833	0.99
501_I	505_H	0.833	0.99
780_I	787_R	0.831	0.99
109_S	113_E	0.830	0.99
671_D	675_I	0.830	0.99
687_K	691_K	0.829	0.99
399_A	403_K	0.829	0.99
684_L	688_D	0.827	0.99
207_E	211_D	0.826	0.99
460_E	464_K	0.826	0.99
337_R	340_E	0.825	0.99
644_L	647_Y	0.824	0.99
317_K	320_R	0.824	0.99
132_G	135_D	0.824	0.99
401_L	404_V	0.823	0.99
712_Q	716_I	0.822	0.99
490_V	493_Q	0.822	0.99
521_I	524_E	0.821	0.99
11_F	38_S	0.820	0.99
516_E	519_K	0.820	0.99
542_T	546_L	0.817	0.99
740_N	762_Y	0.817	0.99
255_N	262_R	0.817	0.99
127_I	130_R	0.816	0.99
485_A	488_D	0.816	0.99
283_N	287_K	0.814	0.99
609_Y	616_L	0.814	0.99
439_Q	442_I	0.813	0.99
805_E	810_L	0.813	0.99
295_A	298_H	0.813	0.99
235_N	238_L	0.811	0.99
584_S	587_L	0.810	0.99
586_I	593_R	0.809	0.99
749_T	755_S	0.809	0.99
665_L	672_I	0.807	0.99
532_Y	539_S	0.807	0.99
514_I	517_E	0.806	0.99
14_H	17_S	0.806	0.99
649_L	653_E	0.805	0.99
277_E	280_N	0.804	0.99
679_I	683_E	0.803	0.99
652_K	655_E	0.801	0.99
537_R	541_Y	0.801	0.99
567_M	570_L	0.800	0.99
445_A	448_Y	0.799	0.99
333_K	337_R	0.798	0.99
88_S	91_E	0.797	0.99
697_N	700_E	0.795	0.98
783_S	810_L	0.795	0.98
171_L	175_L	0.794	0.98
418_I	421_V	0.793	0.98
551_V	555_E	0.792	0.98
506_S	509_E	0.792	0.98
108_V	111_E	0.792	0.98
523_E	526_K	0.790	0.98
616_L	623_L	0.790	0.98
10_N	17_S	0.789	0.98
724_E	727_L	0.788	0.98
461_E	465_K	0.788	0.98
563_I	567_M	0.787	0.98
815_K	838_D	0.785	0.98
598_E	601_K	0.785	0.98
599_M	602_K	0.784	0.98
703_R	708_E	0.784	0.98
570_L	574_L	0.783	0.98
170_N	173_N	0.782	0.98
142_Q	151_L	0.779	0.98
261_L	265_T	0.779	0.98
695_A	707_G	0.778	0.98
783_S	790_I	0.778	0.98
209_L	213_I	0.777	0.98
461_E	464_K	0.777	0.98
504_L	507_E	0.776	0.98
146_G	155_E	0.771	0.98
13_S	38_S	0.771	0.98
120_K	124_L	0.770	0.98
784_I	818_L	0.770	0.98
412_N	420_Q	0.770	0.98
320_R	323_E	0.769	0.98
604_G	607_E	0.768	0.98
276_N	280_N	0.766	0.98
347_Q	351_K	0.765	0.98
330_L	333_K	0.764	0.98
89_T	92_D	0.764	0.98
301_M	308_L	0.763	0.98
312_I	316_E	0.763	0.98
572_S	575_K	0.762	0.98
473_I	476_E	0.761	0.98
472_K	475_R	0.761	0.98
668_L	678_R	0.760	0.98
664_E	671_D	0.760	0.98
737_S	740_N	0.759	0.98
354_S	358_S	0.759	0.98
251_L	254_L	0.758	0.98
310_K	313_E	0.757	0.98
535_F	542_T	0.757	0.98
723_I	793_A	0.755	0.98
788_L	821_I	0.754	0.98
439_Q	446_K	0.753	0.98
194_E	198_R	0.753	0.98
437_H	441_I	0.753	0.98
263_K	267_N	0.753	0.98
739_K	742_E	0.752	0.98
740_N	743_M	0.749	0.98
612_Q	616_L	0.749	0.98
181_I	185_Y	0.748	0.98
412_N	419_S	0.747	0.98
769_L	773_S	0.747	0.98
217_E	220_I	0.745	0.98
808_I	815_K	0.743	0.98
12_L	41_D	0.743	0.98
198_R	202_L	0.742	0.98
609_Y	612_Q	0.742	0.98
57_D	61_R	0.740	0.98
230_Y	233_K	0.740	0.98
632_F	635_N	0.739	0.98
380_V	383_L	0.737	0.98
83_I	92_D	0.737	0.98
763_T	815_K	0.736	0.98
12_L	27_V	0.733	0.97
40_I	126_T	0.733	0.97
780_I	791_A	0.733	0.97
324_E	327_P	0.733	0.97
181_I	184_D	0.732	0.97
172_E	176_R	0.732	0.97
561_E	565_K	0.731	0.97
59_L	62_K	0.731	0.97
791_A	808_I	0.731	0.97
411_K	420_Q	0.730	0.97
460_E	467_T	0.729	0.97
699_L	707_G	0.728	0.97
486_S	489_N	0.727	0.97
640_L	644_L	0.726	0.97
605_I	609_Y	0.726	0.97
366_L	369_D	0.726	0.97
462_E	466_I	0.724	0.97
680_A	684_L	0.724	0.97
59_L	64_S	0.723	0.97
58_N	61_R	0.723	0.97
480_L	483_N	0.723	0.97
809_H	838_D	0.722	0.97
291_Y	298_H	0.721	0.97
221_K	225_D	0.719	0.97
712_Q	719_T	0.718	0.97
50_T	120_K	0.718	0.97
575_K	579_R	0.717	0.97
678_R	685_Q	0.716	0.97
500_E	504_L	0.715	0.97
498_N	501_I	0.715	0.97
105_A	108_V	0.714	0.97
110_N	114_K	0.714	0.97
489_N	493_Q	0.714	0.97
319_I	322_K	0.713	0.97
12_L	45_F	0.713	0.97
57_D	60_I	0.713	0.97
613_V	620_V	0.712	0.97
142_Q	146_G	0.712	0.97
12_L	48_F	0.712	0.97
655_E	659_S	0.711	0.97
806_P	809_H	0.709	0.97
487_Y	491_M	0.707	0.97
540_K	544_E	0.707	0.97
662_E	666_E	0.705	0.97
342_L	349_Y	0.705	0.97
26_N	32_N	0.704	0.97
404_V	407_L	0.704	0.97
467_T	474_E	0.703	0.97
340_E	344_P	0.703	0.97
55_N	58_N	0.703	0.97
806_P	818_L	0.702	0.97
675_I	679_I	0.702	0.97
658_K	662_E	0.702	0.97
672_I	676_S	0.701	0.97
787_R	814_R	0.700	0.97
831_Q	836_T	0.700	0.97
571_E	574_L	0.700	0.97
56_N	61_R	0.699	0.97
332_Y	335_L	0.698	0.97
135_D	139_E	0.698	0.97
727_L	739_K	0.698	0.97
406_S	409_S	0.698	0.97
303_A	307_N	0.697	0.97
178_L	185_Y	0.697	0.97
661_I	664_E	0.697	0.97
700_E	703_R	0.696	0.97
441_I	445_A	0.695	0.96
682_Y	685_Q	0.695	0.96
695_A	701_K	0.695	0.96
129_V	134_L	0.694	0.96
652_K	656_N	0.693	0.96
606_L	613_V	0.693	0.96
130_R	134_L	0.692	0.96
111_E	115_I	0.691	0.96
483_N	487_Y	0.691	0.96
94_L	100_P	0.690	0.96
205_D	209_L	0.688	0.96
5_K	20_Q	0.688	0.96
382_S	385_Q	0.688	0.96
563_I	577_L	0.687	0.96
283_N	286_L	0.687	0.96
409_S	413_E	0.686	0.96
565_K	568_R	0.685	0.96
359_K	362_L	0.685	0.96
716_I	727_L	0.685	0.96
286_L	289_E	0.684	0.96
608_D	611_R	0.683	0.96
84_R	96_R	0.683	0.96
397_L	400_Q	0.682	0.96
548_K	551_V	0.680	0.96
810_L	837_H	0.679	0.96
274_E	278_L	0.679	0.96
787_R	825_A	0.679	0.96
651_L	654_K	0.678	0.96
633_D	636_R	0.678	0.96
11_F	41_D	0.678	0.96
441_I	444_E	0.676	0.96
679_I	685_Q	0.676	0.96
727_L	735_D	0.676	0.96
141_F	144_I	0.676	0.96
624_R	627_V	0.675	0.96
778_E	814_R	0.673	0.96
563_I	566_E	0.672	0.96
379_K	383_L	0.671	0.96
620_V	627_V	0.670	0.96
26_N	833_I	0.669	0.96
346_Y	353_K	0.669	0.96
698_K	702_I	0.669	0.96
760_L	768_T	0.669	0.96
74_S	77_K	0.669	0.96
289_E	292_E	0.669	0.96
84_R	94_L	0.668	0.96
780_I	814_R	0.668	0.96
475_R	478_R	0.667	0.96
401_L	408_I	0.666	0.96
241_T	248_E	0.665	0.96
196_R	200_L	0.665	0.96
702_I	706_L	0.665	0.96
175_L	179_D	0.663	0.95
392_K	396_N	0.661	0.95
102_A	112_I	0.660	0.95
791_A	838_D	0.659	0.95
801_F	830_P	0.659	0.95
779_R	814_R	0.658	0.95
699_L	702_I	0.657	0.95
617_Q	620_V	0.657	0.95
787_R	802_I	0.657	0.95
75_N	115_I	0.657	0.95
165_V	169_K	0.657	0.95
325_L	329_Y	0.656	0.95
744_E	760_L	0.656	0.95
711_L	714_Y	0.656	0.95
465_K	468_N	0.655	0.95
395_L	398_R	0.655	0.95
836_T	842_V	0.655	0.95
307_N	310_K	0.652	0.95
58_N	63_G	0.652	0.95
384_E	387_V	0.652	0.95
452_L	455_N	0.651	0.95
659_S	663_G	0.651	0.95
819_I	838_D	0.650	0.95
323_E	327_P	0.650	0.95
781_A	801_F	0.649	0.95
120_K	123_A	0.649	0.95
10_N	67_G	0.649	0.95
458_E	461_E	0.648	0.95
246_I	249_G	0.647	0.95
268_M	272_E	0.647	0.95
11_F	53_R	0.646	0.95
779_R	783_S	0.645	0.95
40_I	128_I	0.644	0.95
690_E	693_I	0.643	0.95
170_N	174_K	0.638	0.94
10_N	16_H	0.637	0.94
14_H	45_F	0.637	0.94
780_I	815_K	0.636	0.94
260_E	263_K	0.636	0.94
275_I	278_L	0.635	0.94
446_K	449_I	0.635	0.94
798_T	807_T	0.632	0.94
551_V	554_D	0.632	0.94
495_K	499_E	0.632	0.94
800_F	831_Q	0.630	0.94
407_L	414_I	0.630	0.94
564_E	571_E	0.629	0.94
807_T	818_L	0.628	0.94
712_Q	720_K	0.628	0.94
601_K	604_G	0.628	0.94
215_N	218_K	0.626	0.94
378_D	382_S	0.626	0.94
637_Y	640_L	0.626	0.94
544_E	547_D	0.625	0.94
10_N	61_R	0.625	0.94
594_V	597_D	0.624	0.94
155_E	159_D	0.624	0.94
689_R	693_I	0.623	0.94
598_E	602_K	0.623	0.94
736_L	741_V	0.623	0.94
279_E	285_K	0.622	0.94
237_Y	244_L	0.621	0.94
553_L	556_M	0.620	0.94
132_G	810_L	0.619	0.93
213_I	216_L	0.619	0.93
93_R	96_R	0.619	0.93
758_D	770_P	0.618	0.93
696_I	702_I	0.618	0.93
637_Y	642_T	0.617	0.93
119_D	123_A	0.616	0.93
586_I	592_K	0.616	0.93
768_T	771_I	0.614	0.93
19_I	39_I	0.614	0.93
75_N	78_D	0.613	0.93
792_K	822_I	0.612	0.93
574_L	577_L	0.612	0.93
325_L	328_K	0.612	0.93
553_L	560_K	0.609	0.93
696_I	699_L	0.609	0.93
677_N	681_N	0.609	0.93
46_S	69_V	0.608	0.93
736_L	801_F	0.608	0.93
658_K	665_L	0.607	0.93
129_V	132_G	0.607	0.93
634_E	638_N	0.606	0.93
802_I	835_V	0.605	0.93
534_E	537_R	0.605	0.93
371_S	374_S	0.604	0.93
622_N	625_E	0.603	0.93
501_I	508_I	0.603	0.93
392_K	395_L	0.603	0.93
781_A	805_E	0.602	0.92
292_E	296_K	0.602	0.92
130_R	137_I	0.602	0.92
727_L	741_V	0.602	0.92
32_N	814_R	0.602	0.92
236_Q	240_L	0.600	0.92
452_L	459_L	0.600	0.92
778_E	782_L	0.599	0.92
716_I	719_T	0.599	0.92
139_E	779_R	0.598	0.92
636_R	643_S	0.598	0.92
727_L	731_I	0.598	0.92
662_E	665_L	0.598	0.92
353_K	356_L	0.598	0.92
728_N	742_E	0.597	0.92
326_E	330_L	0.597	0.92
778_E	781_A	0.596	0.92
80_I	84_R	0.595	0.92
615_L	618_E	0.594	0.92
230_Y	237_Y	0.594	0.92
412_N	417_N	0.594	0.92
134_L	138_L	0.593	0.92
56_N	59_L	0.591	0.92
179_D	182_E	0.590	0.92
776_G	809_H	0.590	0.92
525_V	528_L	0.589	0.92
737_S	744_E	0.588	0.92
782_L	814_R	0.588	0.92
833_I	838_D	0.587	0.92
781_A	818_L	0.587	0.92
191_T	194_E	0.587	0.92
799_N	806_P	0.585	0.91
649_L	652_K	0.585	0.91
780_I	783_S	0.582	0.91
715_I	719_T	0.582	0.91
647_Y	650_S	0.582	0.91
151_L	154_I	0.581	0.91
660_R	663_G	0.580	0.91
41_D	130_R	0.579	0.91
485_A	489_N	0.577	0.91
90_T	95_I	0.577	0.91
108_V	112_I	0.576	0.91
780_I	838_D	0.575	0.91
684_L	687_K	0.572	0.90
736_L	739_K	0.572	0.90
807_T	819_I	0.572	0.90
86_I	90_T	0.572	0.90
780_I	805_E	0.571	0.90
716_I	731_I	0.571	0.90
673_E	676_S	0.571	0.90
299_T	303_A	0.570	0.90
408_I	411_K	0.569	0.90
583_E	590_E	0.567	0.90
683_E	686_L	0.567	0.90
268_M	271_L	0.567	0.90
807_T	815_K	0.567	0.90
640_L	647_Y	0.567	0.90
244_L	251_L	0.566	0.90
59_L	63_G	0.566	0.90
457_N	461_E	0.566	0.90
780_I	810_L	0.566	0.90
404_V	411_K	0.566	0.90
740_N	744_E	0.566	0.90
705_A	708_E	0.565	0.90
142_Q	149_L	0.565	0.90
188_F	191_T	0.564	0.90
224_K	227_F	0.564	0.90
251_L	258_I	0.563	0.90
81_E	90_T	0.563	0.90
168_R	171_L	0.562	0.90
776_G	780_I	0.562	0.90
188_F	192_V	0.562	0.90
599_M	606_L	0.562	0.90
174_K	177_E	0.561	0.90
193_E	197_A	0.561	0.90
88_S	96_R	0.560	0.90
809_H	815_K	0.560	0.90
374_S	378_D	0.560	0.90
199_V	202_L	0.560	0.90
11_F	67_G	0.560	0.90
154_I	158_I	0.560	0.90
488_D	492_R	0.559	0.89
503_N	506_S	0.559	0.89
798_T	801_F	0.559	0.89
32_N	41_D	0.559	0.89
492_R	496_K	0.558	0.89
45_F	59_L	0.558	0.89
219_R	223_I	0.558	0.89
142_Q	148_I	0.557	0.89
626_E	630_I	0.557	0.89
786_L	809_H	0.557	0.89
360_L	363_K	0.557	0.89
733_K	820_E	0.556	0.89
146_G	149_L	0.556	0.89
778_E	799_N	0.554	0.89
414_I	420_Q	0.554	0.89
699_L	706_L	0.553	0.89
512_K	515_D	0.553	0.89
807_T	832_I	0.553	0.89
585_K	592_K	0.552	0.89
125_S	130_R	0.552	0.89
405_E	408_I	0.552	0.89
480_L	484_K	0.551	0.89
819_I	840_E	0.551	0.89
67_G	75_N	0.551	0.89
87_R	92_D	0.550	0.89
272_E	279_E	0.550	0.89
130_R	133_E	0.549	0.89
285_K	289_E	0.549	0.89
350_L	354_S	0.548	0.89
179_D	183_Q	0.547	0.88
586_I	589_L	0.545	0.88
449_I	456_K	0.545	0.88
814_R	841_V	0.545	0.88
209_L	212_E	0.544	0.88
27_V	41_D	0.543	0.88
263_K	266_E	0.543	0.88
102_A	108_V	0.542	0.88
241_T	244_L	0.542	0.88
787_R	806_P	0.540	0.88
693_I	696_I	0.540	0.88
702_I	707_G	0.539	0.88
11_F	84_R	0.539	0.88
742_E	745_I	0.538	0.88
128_I	781_A	0.537	0.88
792_K	830_P	0.537	0.88
773_S	791_A	0.537	0.88
578_D	582_L	0.537	0.88
184_D	191_T	0.536	0.87
130_R	135_D	0.535	0.87
786_L	807_T	0.534	0.87
720_K	723_I	0.534	0.87
49_R	84_R	0.534	0.87
87_R	90_T	0.533	0.87
512_K	516_E	0.533	0.87
658_K	668_L	0.533	0.87
780_I	801_F	0.532	0.87
185_Y	189_K	0.531	0.87
587_L	591_N	0.531	0.87
130_R	145_M	0.531	0.87
681_N	684_L	0.530	0.87
408_I	416_N	0.529	0.87
712_Q	727_L	0.529	0.87
174_K	181_I	0.528	0.87
518_I	521_I	0.526	0.86
414_I	421_V	0.526	0.86
370_A	373_L	0.526	0.86
412_N	415_I	0.526	0.86
112_I	116_L	0.525	0.86
782_L	805_E	0.524	0.86
33_G	814_R	0.524	0.86
787_R	838_D	0.522	0.86
33_G	781_A	0.522	0.86
174_K	178_L	0.522	0.86
322_K	325_L	0.522	0.86
33_G	835_V	0.522	0.86
780_I	799_N	0.521	0.86
787_R	808_I	0.521	0.86
373_L	376_D	0.521	0.86
129_V	138_L	0.520	0.86
778_E	798_T	0.520	0.86
42_G	69_V	0.519	0.86
787_R	792_K	0.518	0.86
103_R	108_V	0.518	0.86
670_K	673_E	0.518	0.86
737_S	742_E	0.518	0.86
86_I	94_L	0.517	0.86
75_N	80_I	0.517	0.86
694_N	698_K	0.517	0.86
720_K	727_L	0.515	0.85
38_S	48_F	0.515	0.85
557_K	560_K	0.514	0.85
762_Y	768_T	0.514	0.85
348_Q	351_K	0.513	0.85
787_R	800_F	0.513	0.85
792_K	797_N	0.512	0.85
788_L	822_I	0.512	0.85
119_D	122_I	0.512	0.85
719_T	727_L	0.512	0.85
695_A	699_L	0.511	0.85
487_Y	490_V	0.511	0.85
648_N	651_L	0.511	0.85
296_K	300_E	0.510	0.85
29_V	37_S	0.510	0.85
122_I	130_R	0.510	0.85
838_D	842_V	0.510	0.85
454_L	461_E	0.508	0.85
801_F	807_T	0.508	0.85
786_L	790_I	0.507	0.84
98_Q	102_A	0.507	0.84
799_N	807_T	0.506	0.84
817_Y	821_I	0.506	0.84
787_R	809_H	0.505	0.84
200_L	203_K	0.505	0.84
496_K	499_E	0.505	0.84
45_F	84_R	0.505	0.84
32_N	134_L	0.504	0.84
739_K	745_I	0.504	0.84
778_E	783_S	0.504	0.84
778_E	837_H	0.504	0.84
12_L	26_N	0.503	0.84
715_I	720_K	0.503	0.84
81_E	84_R	0.502	0.84
716_I	757_G	0.502	0.84
713_S	717_M	0.502	0.84
699_L	708_E	0.501	0.84
830_P	838_D	0.501	0.84
675_I	678_R	0.500	0.84

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4ux3A	1	0.4769	100	0.632	Contact Map
3auyA	2	0.4167	100	0.638	Contact Map
4ad8A	1	0.478	100	0.66	Contact Map
3zgxA	2	0.3831	100	0.663	Contact Map
1w1wA	2	0.3634	100	0.703	Contact Map
3qf7A	2	0.397	100	0.708	Contact Map
3qktA	2	0.3796	100	0.729	Contact Map
4i99A	2	0.3391	100	0.741	Contact Map
4abyA	1	0.3796	100	0.742	Contact Map
3qksA	1	0.2141	100	0.776	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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