Q97WF4 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q97WF4 - Uncharacterized protein

UniProt:	Q97WF4	Sequences: MFQDPTFQITVTQLQYLLSIISGILVGFSLGLIGGGGSILAIPLLLYFVGLANGIPPGSPEYTYITHLTLGTTALAVGLNSYINSYMHFRRGNVRVPEGIIFTIPGVIGDVIGAYLSHLMSGALILFLFGFLMIAVAIRMWRSKCNPNRSVLYNNSHKLSLRERIKVTKVIPAGFLVGFASGYFGIGGGFLVVPGLLFSTGLDMLRAVGTSLIAVGTFGVTAAITYAVYGYVDIVISLLYLLGGVVGGYTGSTIASRMPRQTLRKLFAIIIIVVAIYTMYINRVGVVELLHFL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	293 (242)
Sequences:	7627 (5370)
Seq/√Len:	345.2

ECOLI - YFCA
BACSU - YUNE YRKJ YJNA YDHB YTNM
HALSA - O54662
SULSO - Q97WF4 Q981D0 Q97UT0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
109_G	175_F	3.844	1.00
28_F	254_I	3.317	1.00
277_Y	281_I	3.156	1.00
116_L	179_F	2.872	1.00
83_I	245_V	2.767	1.00
20_I	243_G	2.688	1.00
79_L	241_L	2.642	1.00
95_R	206_R	2.612	1.00
83_I	249_Y	2.474	1.00
89_F	96_V	2.395	1.00
173_A	195_G	2.367	1.00
137_A	275_A	2.307	1.00
261_Q	265_K	2.265	1.00
138_I	142_R	2.210	1.00
22_S	44_L	2.193	1.00
24_I	246_V	2.176	1.00
103_T	217_T	2.169	1.00
105_P	171_I	2.087	1.00
262_T	265_K	2.050	1.00
74_A	222_A	2.040	1.00
23_G	240_Y	2.006	1.00
99_G	213_I	1.960	1.00
203_D	206_R	1.918	1.00
276_I	280_Y	1.905	1.00
253_T	257_R	1.903	1.00
130_G	275_A	1.900	1.00
111_V	225_T	1.860	1.00
68_L	71_G	1.850	1.00
272_I	276_I	1.849	1.00
95_R	98_E	1.759	1.00
175_F	179_F	1.755	1.00
75_L	237_S	1.753	1.00
98_E	202_L	1.749	1.00
87_M	252_S	1.746	1.00
72_T	237_S	1.718	1.00
137_A	272_I	1.707	1.00
82_Y	216_G	1.688	1.00
45_L	240_Y	1.688	1.00
259_P	262_T	1.680	1.00
97_P	100_I	1.658	1.00
52_A	66_T	1.650	1.00
227_A	234_I	1.638	1.00
88_H	255_A	1.626	1.00
88_H	93_N	1.618	1.00
238_L	242_L	1.606	1.00
242_L	246_V	1.575	1.00
265_K	269_I	1.573	1.00
100_I	104_I	1.564	1.00
20_I	239_L	1.559	1.00
131_F	135_A	1.522	1.00
134_I	275_A	1.512	1.00
249_Y	253_T	1.477	1.00
97_P	101_I	1.470	1.00
100_I	103_T	1.448	1.00
26_V	40_L	1.445	1.00
68_L	233_D	1.445	1.00
99_G	210_T	1.443	1.00
137_A	268_A	1.439	1.00
233_D	236_I	1.437	1.00
16_Y	239_L	1.437	1.00
85_S	213_I	1.425	1.00
106_G	218_F	1.424	1.00
168_T	172_P	1.424	1.00
193_V	207_A	1.423	1.00
28_F	250_T	1.418	1.00
91_R	256_S	1.418	1.00
115_Y	119_L	1.398	1.00
21_I	25_L	1.395	1.00
177_V	191_L	1.393	1.00
132_L	184_F	1.377	1.00
24_I	247_G	1.348	1.00
107_V	221_T	1.347	1.00
112_I	175_F	1.335	1.00
17_L	21_I	1.332	1.00
84_N	248_G	1.331	1.00
235_V	239_L	1.326	1.00
170_V	200_T	1.313	1.00
23_G	243_G	1.309	1.00
109_G	179_F	1.297	1.00
70_L	226_Y	1.291	1.00
140_M	267_F	1.291	1.00
96_V	100_I	1.283	1.00
224_I	228_V	1.280	1.00
52_A	68_L	1.279	1.00
197_L	207_A	1.278	1.00
120_M	183_Y	1.277	1.00
141_W	268_A	1.274	1.00
110_D	222_A	1.258	1.00
38_S	182_G	1.256	1.00
111_V	115_Y	1.251	1.00
145_C	148_N	1.249	1.00
104_I	108_I	1.240	1.00
225_T	229_Y	1.233	1.00
109_G	113_G	1.229	1.00
102_F	196_L	1.227	1.00
130_G	279_M	1.204	1.00
193_V	211_S	1.197	1.00
114_A	222_A	1.186	1.00
269_I	273_V	1.184	1.00
89_F	94_V	1.172	1.00
85_S	89_F	1.157	1.00
192_V	214_A	1.138	1.00
24_I	250_T	1.138	1.00
24_I	243_G	1.137	1.00
188_G	192_V	1.123	1.00
78_G	220_V	1.122	1.00
193_V	208_V	1.119	1.00
205_L	255_A	1.114	1.00
172_P	176_L	1.106	1.00
88_H	252_S	1.100	1.00
51_L	236_I	1.099	1.00
96_V	99_G	1.091	1.00
142_R	145_C	1.079	1.00
247_G	251_G	1.079	1.00
105_P	109_G	1.071	1.00
20_I	242_L	1.070	1.00
124_L	128_L	1.067	1.00
105_P	174_G	1.066	1.00
231_Y	235_V	1.062	1.00
188_G	194_P	1.040	1.00
88_H	209_G	1.032	1.00
85_S	216_G	1.031	1.00
215_V	218_F	1.025	1.00
19_S	240_Y	1.017	1.00
112_I	115_Y	1.009	1.00
84_N	212_L	1.006	1.00
26_V	41_A	1.002	1.00
114_A	225_T	0.993	1.00
87_M	91_R	0.971	1.00
96_V	213_I	0.963	1.00
18_L	21_I	0.962	1.00
71_G	232_V	0.958	1.00
85_S	96_V	0.958	1.00
50_G	69_T	0.955	1.00
127_F	131_F	0.952	1.00
168_T	171_I	0.951	1.00
122_G	126_L	0.947	1.00
145_C	149_R	0.947	1.00
94_V	210_T	0.942	1.00
93_N	209_G	0.937	1.00
105_P	108_I	0.928	1.00
42_I	73_T	0.914	1.00
78_G	223_A	0.911	1.00
94_V	99_G	0.905	1.00
253_T	256_S	0.901	1.00
41_A	240_Y	0.893	1.00
70_L	117_S	0.892	1.00
273_V	277_Y	0.890	1.00
166_K	169_K	0.888	1.00
273_V	276_I	0.881	1.00
46_L	66_T	0.880	1.00
245_V	249_Y	0.880	1.00
19_S	236_I	0.878	1.00
75_L	223_A	0.875	1.00
135_A	139_R	0.875	1.00
174_G	192_V	0.873	1.00
114_A	221_T	0.870	1.00
238_L	241_L	0.869	1.00
262_T	266_L	0.869	1.00
87_M	249_Y	0.864	1.00
86_Y	90_R	0.861	1.00
117_S	226_Y	0.856	1.00
73_T	77_V	0.854	1.00
81_S	185_G	0.853	1.00
223_A	237_S	0.852	1.00
181_S	218_F	0.852	1.00
106_G	214_A	0.848	1.00
112_I	179_F	0.847	1.00
31_G	252_S	0.845	1.00
72_T	232_V	0.838	1.00
106_G	192_V	0.836	1.00
197_L	204_M	0.835	1.00
169_K	172_P	0.835	1.00
226_Y	231_Y	0.834	1.00
18_L	22_S	0.831	1.00
143_S	264_R	0.831	1.00
30_L	38_S	0.830	1.00
248_G	252_S	0.828	1.00
80_N	244_G	0.824	1.00
30_L	181_S	0.823	1.00
177_V	188_G	0.818	1.00
52_A	67_H	0.816	1.00
20_I	24_I	0.814	1.00
164_R	167_V	0.812	1.00
123_A	127_F	0.812	1.00
27_G	37_G	0.812	1.00
77_V	181_S	0.808	1.00
23_G	236_I	0.801	1.00
26_V	44_L	0.800	1.00
185_G	188_G	0.798	1.00
204_M	208_V	0.793	1.00
70_L	74_A	0.790	1.00
268_A	272_I	0.784	1.00
32_L	263_L	0.783	1.00
31_G	84_N	0.775	1.00
81_S	215_V	0.774	1.00
77_V	219_G	0.774	1.00
243_G	247_G	0.774	1.00
258_M	262_T	0.772	1.00
38_S	77_V	0.770	1.00
99_G	214_A	0.770	1.00
32_L	251_G	0.763	1.00
87_M	253_T	0.760	1.00
112_I	116_L	0.757	1.00
83_I	87_M	0.757	1.00
23_G	27_G	0.757	1.00
267_F	271_I	0.756	1.00
212_L	215_V	0.752	1.00
121_S	124_L	0.750	1.00
102_F	214_A	0.748	1.00
115_Y	118_H	0.747	1.00
124_L	127_F	0.747	1.00
51_L	68_L	0.745	1.00
255_A	263_L	0.744	1.00
39_I	133_M	0.739	1.00
74_A	77_V	0.739	1.00
149_R	153_Y	0.738	1.00
75_L	241_L	0.730	0.99
188_G	215_V	0.730	0.99
20_I	246_V	0.728	0.99
51_L	233_D	0.728	0.99
204_M	267_F	0.725	0.99
181_S	188_G	0.725	0.99
239_L	243_G	0.724	0.99
126_L	281_I	0.721	0.99
71_G	223_A	0.720	0.99
89_F	92_G	0.717	0.99
127_F	130_G	0.714	0.99
70_L	125_I	0.713	0.99
134_I	272_I	0.712	0.99
110_D	114_A	0.710	0.99
30_L	40_L	0.708	0.99
76_A	244_G	0.707	0.99
116_L	119_L	0.703	0.99
67_H	71_G	0.703	0.99
113_G	179_F	0.702	0.99
164_R	168_T	0.702	0.99
134_I	138_I	0.699	0.99
72_T	233_D	0.698	0.99
101_I	104_I	0.696	0.99
20_I	23_G	0.694	0.99
36_G	78_G	0.693	0.99
27_G	244_G	0.692	0.99
218_F	244_G	0.691	0.99
115_Y	225_T	0.690	0.99
172_P	175_F	0.688	0.99
101_I	167_V	0.687	0.99
97_P	167_V	0.687	0.99
130_G	134_I	0.687	0.99
30_L	80_N	0.683	0.99
86_Y	89_F	0.682	0.99
74_A	219_G	0.681	0.99
30_L	215_V	0.680	0.99
235_V	238_L	0.679	0.99
93_N	256_S	0.678	0.99
33_I	248_G	0.678	0.99
46_L	69_T	0.670	0.99
137_A	141_W	0.668	0.99
108_I	112_I	0.665	0.99
82_Y	86_Y	0.663	0.99
23_G	41_A	0.662	0.99
185_G	211_S	0.659	0.99
275_A	279_M	0.659	0.99
174_G	178_G	0.651	0.99
192_V	196_L	0.651	0.99
98_E	206_R	0.650	0.99
130_G	278_T	0.650	0.99
149_R	152_L	0.649	0.99
143_S	146_N	0.646	0.99
223_A	227_A	0.644	0.99
16_Y	20_I	0.643	0.99
213_I	217_T	0.639	0.99
30_L	77_V	0.635	0.99
259_P	263_L	0.628	0.98
68_L	72_T	0.627	0.98
211_S	215_V	0.626	0.98
51_L	69_T	0.621	0.98
74_A	185_G	0.621	0.98
114_A	182_G	0.620	0.98
30_L	35_G	0.619	0.98
36_G	43_P	0.619	0.98
189_G	211_S	0.619	0.98
81_S	248_G	0.616	0.98
38_S	186_I	0.614	0.98
31_G	248_G	0.614	0.98
24_I	28_F	0.612	0.98
147_P	150_S	0.608	0.98
195_G	199_S	0.607	0.98
19_S	182_G	0.607	0.98
78_G	81_S	0.606	0.98
108_I	111_V	0.606	0.98
77_V	188_G	0.602	0.98
186_I	190_F	0.600	0.98
147_P	151_V	0.599	0.98
37_G	186_I	0.597	0.98
74_A	181_S	0.594	0.98
41_A	77_V	0.592	0.98
148_N	151_V	0.591	0.98
187_G	215_V	0.586	0.97
32_L	258_M	0.586	0.97
107_V	217_T	0.583	0.97
137_A	271_I	0.583	0.97
92_G	95_R	0.581	0.97
277_Y	280_Y	0.580	0.97
77_V	81_S	0.578	0.97
141_W	272_I	0.577	0.97
83_I	248_G	0.572	0.97
227_A	232_V	0.572	0.97
67_H	70_L	0.568	0.97
250_T	253_T	0.568	0.97
120_M	124_L	0.568	0.97
181_S	186_I	0.567	0.97
66_T	122_G	0.561	0.97
129_F	184_F	0.561	0.97
118_H	229_Y	0.560	0.97
191_L	194_P	0.560	0.97
254_I	258_M	0.558	0.97
24_I	27_G	0.558	0.97
32_L	254_I	0.557	0.97
47_Y	278_T	0.555	0.97
207_A	211_S	0.553	0.96
42_I	184_F	0.551	0.96
93_N	206_R	0.550	0.96
87_M	90_R	0.549	0.96
169_K	195_G	0.546	0.96
185_G	226_Y	0.544	0.96
18_L	49_V	0.543	0.96
140_M	194_P	0.540	0.96
66_T	69_T	0.540	0.96
232_V	237_S	0.540	0.96
37_G	73_T	0.539	0.96
196_L	210_T	0.538	0.96
38_S	41_A	0.537	0.96
70_L	208_V	0.534	0.96
42_I	129_F	0.533	0.96
116_L	120_M	0.533	0.96
66_T	70_L	0.531	0.96
33_I	208_V	0.530	0.95
133_M	271_I	0.530	0.95
165_I	169_K	0.528	0.95
258_M	263_L	0.525	0.95
237_S	241_L	0.525	0.95
34_G	187_G	0.525	0.95
111_V	228_V	0.523	0.95
79_L	245_V	0.522	0.95
264_R	268_A	0.521	0.95
205_L	260_R	0.521	0.95
19_S	49_V	0.518	0.95
81_S	216_G	0.517	0.95
27_G	32_L	0.517	0.95
91_R	253_T	0.516	0.95
66_T	125_I	0.516	0.95
196_L	214_A	0.515	0.95
110_D	221_T	0.515	0.95
204_M	260_R	0.515	0.95
81_S	188_G	0.512	0.95
125_I	183_Y	0.511	0.95
85_S	94_V	0.510	0.94
19_S	239_L	0.507	0.94
218_F	223_A	0.506	0.94
246_V	250_T	0.505	0.94
188_G	211_S	0.503	0.94
212_L	216_G	0.500	0.94

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2gfpA	2	0.8703	77.1	0.925	Contact Map
1pw4A	1	0.8805	73.4	0.928	Contact Map
3o7qA	1	0.8908	64.6	0.932	Contact Map
3wdoA	1	0.8874	60.8	0.934	Contact Map
4j05A	3	0.8567	45.9	0.939	Contact Map
3qe7A	2	0.4778	43.8	0.94	Contact Map
4pypA	1	0.8942	38.1	0.942	Contact Map
4m64A	1	0.8259	32.2	0.944	Contact Map
2cfqA	1	0.8498	31.7	0.944	Contact Map
3l1lA	2	0.4505	26.3	0.947	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0088 seconds.