Q97WE1 - SULSO - GREMLIN Contacts

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Q97WE1 - Uncharacterized protein

UniProt:	Q97WE1	Sequences: MSSDVPLYNDIKDRISRARALALTLGDLVGKVSRYIPNKLDEENNVVNVTVDPNTYYKYPFLGKIGIFLGAIDIKTLYFVLLRVIGYERNDASSLFMGDSNVLNNIGLSDDEPGSLITNVTLRCEMLTKVDFLSSSEPDGADIILEPQSPVIIPKAEVIERSLGTTRGLLRLGFLDVAYSKVRVSTSLDDLNFHMLILGTTGAGKTSFIKDLIAGLNVTNEEGSKIFILDATGDYYHIFLPPDKSDKVVMKGVEEFTQLYGAIVKGINVDIIYPISKSWVKKYLDGAKSAGSITKMYFDMFVKPILNHLNNKGISIYASIINNKIIISNADWSSQVTVYPFYFRFKDVKTILHKLNPYFTEQASHFIKIMIRKKGKDIANLDDLIDQFNENSLEGVEIHKSTRENIVRGLYLLKETQLFDVGVERFPLGKILKDSSSSTLIFDLYNSELDDFSQKILTYYFLDRLFEFRERQMRSGNVKGRNVIIIDEAHRFFPSSKGGEEDTNYIRRVAGKIATMMRLGRRRKIGFVFATHNPNDLSDIIIQLANTKIIFRIKSEVAEALGLSKTEAKILNWERNGVAYLLTPWLREGKIKIKAPVPPPLGHYDLSKT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	609 (507)
Sequences:	1223 (993)
Seq/√Len:	44.1

HALSA - Q9HNY0
SULSO - Q97WE1 Q97YJ6 Q97ZV6 Q97WL6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
82_L	124_C	6.187	1.00
270_D	274_P	4.070	1.00
274_P	278_S	3.811	1.00
208_F	593_I	3.615	1.00
266_G	270_D	3.513	1.00
195_M	528_V	3.298	1.00
196_L	545_A	3.101	1.00
69_L	151_V	3.073	1.00
271_I	274_P	2.978	1.00
443_D	447_S	2.937	1.00
581_L	591_I	2.903	1.00
298_F	302_V	2.897	1.00
577_G	595_A	2.780	1.00
233_G	443_D	2.729	1.00
270_D	273_Y	2.713	1.00
275_I	278_S	2.682	1.00
272_I	278_S	2.592	1.00
549_I	579_A	2.565	1.00
290_A	294_T	2.560	1.00
514_A	538_S	2.550	1.00
171_R	594_K	2.541	1.00
267_I	270_D	2.532	1.00
278_S	282_K	2.512	1.00
279_W	282_K	2.490	1.00
211_D	215_G	2.453	1.00
533_N	583_T	2.411	1.00
267_I	273_Y	2.336	1.00
266_G	272_I	2.320	1.00
384_L	388_F	2.265	1.00
533_N	557_V	2.256	1.00
265_K	268_N	2.255	1.00
69_L	124_C	2.248	1.00
294_T	302_V	2.221	1.00
268_N	273_Y	2.215	1.00
174_F	183_R	2.209	1.00
69_L	82_L	2.206	1.00
263_I	268_N	2.164	1.00
270_D	278_S	2.152	1.00
270_D	275_I	2.135	1.00
197_I	209_I	2.122	1.00
265_K	270_D	2.114	1.00
208_F	551_F	2.099	0.99
280_V	283_Y	2.093	0.99
268_N	271_I	2.091	0.99
282_K	286_G	2.075	0.99
207_S	577_G	2.037	0.99
493_F	513_I	2.026	0.99
297_Y	301_F	2.019	0.99
268_N	274_P	2.012	0.99
39_K	123_R	1.958	0.99
171_R	183_R	1.951	0.99
384_L	387_Q	1.946	0.99
536_D	540_I	1.912	0.99
487_D	515_T	1.912	0.99
280_V	285_D	1.900	0.99
263_I	270_D	1.900	0.99
263_I	266_G	1.882	0.99
380_N	383_D	1.876	0.99
290_A	302_V	1.875	0.99
202_G	521_R	1.873	0.99
230_D	522_R	1.864	0.99
280_V	284_L	1.862	0.99
273_Y	278_S	1.855	0.99
359_F	362_Q	1.820	0.98
294_T	298_F	1.819	0.98
274_P	282_K	1.817	0.98
267_I	271_I	1.806	0.98
42_E	124_C	1.802	0.98
462_L	484_I	1.794	0.98
290_A	297_Y	1.780	0.98
543_Q	557_V	1.779	0.98
232_T	530_A	1.776	0.98
275_I	280_V	1.749	0.98
299_D	303_K	1.738	0.98
292_S	297_Y	1.715	0.98
543_Q	583_T	1.712	0.98
517_M	527_F	1.705	0.98
230_D	489_A	1.697	0.98
268_N	272_I	1.687	0.98
294_T	297_Y	1.675	0.97
267_I	272_I	1.664	0.97
533_N	540_I	1.654	0.97
490_H	534_P	1.649	0.97
196_L	487_D	1.637	0.97
523_R	544_L	1.635	0.97
266_G	273_Y	1.634	0.97
335_Q	343_F	1.633	0.97
519_L	522_R	1.630	0.97
557_V	583_T	1.630	0.97
276_S	280_V	1.597	0.97
462_L	516_M	1.596	0.97
208_F	549_I	1.596	0.97
204_G	489_A	1.579	0.96
227_F	442_F	1.577	0.96
204_G	230_D	1.576	0.96
145_L	589_G	1.572	0.96
275_I	282_K	1.560	0.96
272_I	275_I	1.557	0.96
304_P	311_N	1.549	0.96
194_H	552_R	1.548	0.96
487_D	536_D	1.546	0.96
232_T	551_F	1.526	0.95
353_H	357_P	1.525	0.95
36_I	40_L	1.520	0.95
287_A	290_A	1.520	0.95
265_K	274_P	1.515	0.95
381_L	384_L	1.511	0.95
519_L	557_V	1.502	0.95
406_I	409_G	1.501	0.95
354_K	362_Q	1.500	0.95
263_I	274_P	1.495	0.95
152_I	158_V	1.489	0.95
290_A	296_M	1.488	0.95
339_Y	342_Y	1.486	0.95
145_L	513_I	1.481	0.95
360_T	363_A	1.480	0.95
278_S	283_Y	1.476	0.95
550_I	571_L	1.475	0.95
290_A	295_K	1.439	0.94
297_Y	300_M	1.438	0.94
336_V	339_Y	1.436	0.94
346_K	350_T	1.432	0.94
483_V	528_V	1.428	0.94
209_I	530_A	1.427	0.94
276_S	284_L	1.423	0.93
293_I	296_M	1.419	0.93
292_S	298_F	1.405	0.93
339_Y	343_F	1.394	0.93
490_H	519_L	1.392	0.93
266_G	271_I	1.389	0.93
532_H	544_L	1.386	0.92
234_D	522_R	1.377	0.92
342_Y	348_V	1.377	0.92
514_A	540_I	1.363	0.92
266_G	274_P	1.354	0.92
419_F	422_G	1.353	0.92
519_L	543_Q	1.351	0.92
270_D	282_K	1.348	0.91
384_L	389_N	1.348	0.91
522_R	544_L	1.342	0.91
145_L	493_F	1.341	0.91
207_S	596_P	1.341	0.91
544_L	557_V	1.340	0.91
549_I	581_L	1.338	0.91
487_D	530_A	1.337	0.91
300_M	303_K	1.335	0.91
275_I	279_W	1.331	0.91
399_H	402_T	1.318	0.90
232_T	522_R	1.314	0.90
279_W	284_L	1.307	0.90
396_V	400_K	1.303	0.90
128_T	235_Y	1.301	0.90
523_R	557_V	1.298	0.90
402_T	405_N	1.295	0.90
336_V	340_P	1.288	0.89
335_Q	340_P	1.286	0.89
533_N	544_L	1.276	0.89
265_K	272_I	1.270	0.89
534_P	544_L	1.265	0.89
336_V	342_Y	1.261	0.88
297_Y	302_V	1.257	0.88
334_S	337_T	1.236	0.87
450_D	558_A	1.234	0.87
297_Y	306_L	1.232	0.87
204_G	490_H	1.232	0.87
426_F	430_K	1.231	0.87
302_V	305_I	1.226	0.87
399_H	405_N	1.225	0.87
430_K	433_K	1.225	0.87
340_P	343_F	1.225	0.87
263_I	267_I	1.225	0.87
443_D	526_G	1.220	0.87
352_L	358_Y	1.213	0.86
306_L	313_G	1.209	0.86
140_G	538_S	1.203	0.86
302_V	306_L	1.189	0.85
290_A	293_I	1.184	0.85
269_V	274_P	1.182	0.85
337_T	348_V	1.174	0.84
418_L	423_V	1.173	0.84
265_K	271_I	1.172	0.84
230_D	490_H	1.167	0.84
230_D	235_Y	1.167	0.84
32_V	157_E	1.164	0.84
345_F	348_V	1.158	0.84
556_E	559_E	1.157	0.84
272_I	282_K	1.155	0.84
268_N	278_S	1.153	0.83
537_L	545_A	1.153	0.83
358_Y	361_E	1.150	0.83
282_K	285_D	1.148	0.83
514_A	531_T	1.146	0.83
285_D	292_S	1.146	0.83
390_E	393_L	1.134	0.82
376_K	379_A	1.134	0.82
531_T	583_T	1.132	0.82
279_W	285_D	1.130	0.82
84_V	119_N	1.128	0.82
336_V	341_F	1.126	0.82
70_G	79_F	1.122	0.82
235_Y	522_R	1.121	0.82
519_L	544_L	1.120	0.82
418_L	421_V	1.115	0.81
533_N	543_Q	1.114	0.81
583_T	589_G	1.113	0.81
416_T	419_F	1.112	0.81
336_V	343_F	1.112	0.81
493_F	537_L	1.112	0.81
341_F	345_F	1.111	0.81
274_P	280_V	1.106	0.81
50_T	53_P	1.105	0.81
204_G	235_Y	1.103	0.81
282_K	290_A	1.102	0.80
519_L	532_H	1.100	0.80
310_N	313_G	1.099	0.80
34_R	41_D	1.097	0.80
373_K	376_K	1.097	0.80
292_S	301_F	1.097	0.80
524_K	552_R	1.096	0.80
267_I	278_S	1.096	0.80
271_I	275_I	1.094	0.80
518_R	577_G	1.092	0.80
268_N	275_I	1.089	0.80
386_D	389_N	1.088	0.80
232_T	557_V	1.084	0.79
204_G	531_T	1.083	0.79
174_F	181_K	1.082	0.79
336_V	344_R	1.079	0.79
175_L	184_V	1.067	0.78
186_T	581_L	1.066	0.78
227_F	465_L	1.064	0.78
232_T	533_N	1.063	0.78
194_H	521_R	1.063	0.78
519_L	533_N	1.053	0.77
271_I	282_K	1.053	0.77
270_D	276_S	1.052	0.77
157_E	465_L	1.051	0.77
173_G	581_L	1.048	0.77
66_G	547_T	1.048	0.77
465_L	482_N	1.043	0.77
199_G	536_D	1.039	0.76
285_D	288_K	1.038	0.76
470_E	530_A	1.038	0.76
69_L	240_L	1.036	0.76
519_L	523_R	1.034	0.76
215_G	594_K	1.029	0.76
231_A	580_Y	1.028	0.76
63_G	231_A	1.027	0.76
70_G	158_V	1.024	0.75
571_L	579_A	1.020	0.75
391_N	395_G	1.017	0.75
381_L	387_Q	1.015	0.75
282_K	292_S	1.013	0.75
232_T	519_L	1.013	0.75
592_K	595_A	1.012	0.74
577_G	596_P	1.010	0.74
230_D	531_T	1.008	0.74
295_K	299_D	1.005	0.74
519_L	583_T	1.005	0.74
540_I	554_K	1.001	0.74
285_D	297_Y	1.000	0.74
490_H	533_N	0.999	0.74
288_K	292_S	0.997	0.73
194_H	520_G	0.995	0.73
426_F	429_G	0.993	0.73
276_S	282_K	0.992	0.73
494_P	537_L	0.992	0.73
275_I	284_L	0.992	0.73
537_L	596_P	0.990	0.73
238_I	487_D	0.987	0.73
141_A	523_R	0.986	0.73
309_L	312_K	0.986	0.73
283_Y	286_G	0.981	0.72
522_R	532_H	0.980	0.72
270_D	280_V	0.977	0.72
346_K	349_K	0.975	0.72
213_I	528_V	0.972	0.71
380_N	384_L	0.971	0.71
214_A	597_V	0.965	0.71
234_D	544_L	0.959	0.70
204_G	522_R	0.954	0.70
361_E	371_I	0.951	0.70
274_P	283_Y	0.950	0.70
281_K	284_L	0.950	0.70
352_L	355_L	0.947	0.69
28_L	31_K	0.946	0.69
264_V	272_I	0.946	0.69
253_V	256_F	0.946	0.69
289_S	292_S	0.945	0.69
145_L	234_D	0.934	0.68
529_F	557_V	0.933	0.68
194_H	524_K	0.929	0.68
343_F	347_D	0.928	0.68
420_D	424_E	0.928	0.68
128_T	520_G	0.926	0.68
288_K	294_T	0.923	0.67
271_I	278_S	0.923	0.67
338_V	341_F	0.922	0.67
231_A	547_T	0.921	0.67
214_A	596_P	0.915	0.67
356_N	359_F	0.912	0.67
159_I	173_G	0.912	0.67
71_A	82_L	0.909	0.66
354_K	358_Y	0.909	0.66
246_D	249_V	0.909	0.66
234_D	518_R	0.909	0.66
126_M	576_N	0.907	0.66
305_I	311_N	0.906	0.66
359_F	363_A	0.905	0.66
392_S	395_G	0.905	0.66
466_F	515_T	0.905	0.66
533_N	554_K	0.905	0.66
269_V	273_Y	0.904	0.66
196_L	583_T	0.904	0.66
270_D	286_G	0.904	0.66
427_P	431_I	0.903	0.66
82_L	126_M	0.901	0.66
544_L	583_T	0.899	0.65
210_K	596_P	0.899	0.65
344_R	347_D	0.899	0.65
206_T	230_D	0.896	0.65
211_D	555_S	0.893	0.65
294_T	299_D	0.892	0.65
151_V	162_S	0.892	0.65
200_T	548_K	0.891	0.65
337_T	340_P	0.883	0.64
427_P	430_K	0.883	0.64
346_K	357_P	0.881	0.64
297_Y	305_I	0.880	0.64
296_M	301_F	0.880	0.64
583_T	588_E	0.880	0.64
267_I	274_P	0.880	0.64
274_P	279_W	0.879	0.64
307_N	312_K	0.876	0.63
70_G	154_P	0.876	0.63
259_L	262_A	0.871	0.63
70_G	152_I	0.869	0.63
262_A	266_G	0.869	0.63
263_I	271_I	0.869	0.63
197_I	202_G	0.869	0.63
275_I	285_D	0.868	0.63
395_G	400_K	0.867	0.63
417_Q	421_V	0.865	0.62
489_A	557_V	0.863	0.62
193_F	490_H	0.863	0.62
194_H	202_G	0.861	0.62
389_N	392_S	0.860	0.62
332_W	339_Y	0.857	0.62
247_K	250_M	0.857	0.62
485_I	528_V	0.856	0.62
351_I	355_L	0.852	0.61
289_S	293_I	0.851	0.61
284_L	288_K	0.850	0.61
295_K	298_F	0.850	0.61
299_D	306_L	0.849	0.61
301_F	304_P	0.849	0.61
189_D	531_T	0.849	0.61
232_T	538_S	0.847	0.61
490_H	518_R	0.844	0.60
187_S	190_D	0.843	0.60
276_S	285_D	0.843	0.60
349_K	355_L	0.842	0.60
207_S	454_Q	0.842	0.60
347_D	380_N	0.841	0.60
198_L	550_I	0.840	0.60
538_S	547_T	0.839	0.60
263_I	272_I	0.838	0.60
288_K	299_D	0.838	0.60
274_P	284_L	0.838	0.60
232_T	578_V	0.837	0.60
285_D	293_I	0.835	0.60
489_A	522_R	0.834	0.60
486_I	494_P	0.832	0.59
72_I	152_I	0.830	0.59
201_T	490_H	0.829	0.59
462_L	513_I	0.828	0.59
335_Q	339_Y	0.827	0.59
529_F	583_T	0.827	0.59
335_Q	341_F	0.823	0.58
490_H	522_R	0.822	0.58
258_Q	263_I	0.821	0.58
304_P	308_H	0.819	0.58
296_M	300_M	0.819	0.58
518_R	547_T	0.817	0.58
339_Y	344_R	0.816	0.58
188_L	541_I	0.815	0.58
191_L	201_T	0.813	0.58
191_L	526_G	0.813	0.58
267_I	275_I	0.812	0.57
69_L	228_I	0.812	0.57
305_I	309_L	0.808	0.57
346_K	354_K	0.807	0.57
431_I	435_S	0.805	0.57
350_T	354_K	0.804	0.57
517_M	541_I	0.798	0.56
557_V	589_G	0.795	0.56
194_H	546_N	0.795	0.56
207_S	214_A	0.795	0.56
66_G	78_Y	0.789	0.55
235_Y	489_A	0.788	0.55
189_D	214_A	0.787	0.55
298_F	306_L	0.787	0.55
352_L	359_F	0.784	0.55
554_K	583_T	0.784	0.55
575_R	578_V	0.783	0.55
84_V	161_R	0.783	0.55
145_L	489_A	0.782	0.55
379_A	384_L	0.782	0.55
228_I	279_W	0.782	0.55
400_K	404_E	0.781	0.55
128_T	206_T	0.780	0.54
203_A	540_I	0.779	0.54
204_G	534_P	0.779	0.54
294_T	305_I	0.776	0.54
210_K	583_T	0.776	0.54
158_V	550_I	0.775	0.54
232_T	531_T	0.774	0.54
344_R	348_V	0.773	0.54
267_I	279_W	0.771	0.54
519_L	529_F	0.769	0.53
383_D	387_Q	0.768	0.53
391_N	394_E	0.768	0.53
353_H	360_T	0.767	0.53
288_K	295_K	0.766	0.53
466_F	470_E	0.765	0.53
531_T	540_I	0.763	0.53
356_N	362_Q	0.761	0.53
388_F	391_N	0.761	0.53
285_D	294_T	0.756	0.52
200_T	531_T	0.755	0.52
418_L	422_G	0.751	0.52
518_R	536_D	0.750	0.52
276_S	290_A	0.749	0.51
396_V	404_E	0.749	0.51
519_L	534_P	0.747	0.51
208_F	211_D	0.747	0.51
540_I	583_T	0.746	0.51
272_I	276_S	0.746	0.51
198_L	545_A	0.745	0.51
350_T	363_A	0.744	0.51
230_D	544_L	0.743	0.51
574_E	589_G	0.741	0.51
213_I	228_I	0.741	0.51
492_F	536_D	0.741	0.51
206_T	522_R	0.741	0.51
210_K	533_N	0.739	0.50
284_L	292_S	0.738	0.50
286_G	292_S	0.737	0.50
518_R	522_R	0.737	0.50
334_S	344_R	0.735	0.50
551_F	579_A	0.735	0.50
230_D	534_P	0.734	0.50
230_D	583_T	0.733	0.50
232_T	491_R	0.732	0.50
272_I	280_V	0.731	0.50
351_I	354_K	0.729	0.50
291_G	294_T	0.728	0.49
232_T	583_T	0.727	0.49
377_D	380_N	0.726	0.49
276_S	279_W	0.722	0.49
397_E	402_T	0.722	0.49
338_V	348_V	0.721	0.49
442_F	581_L	0.720	0.49
491_R	519_L	0.719	0.49
193_F	546_N	0.717	0.48
381_L	386_D	0.717	0.48
277_K	283_Y	0.716	0.48
140_G	463_D	0.712	0.48
128_T	522_R	0.711	0.48
354_K	361_E	0.709	0.48
267_I	307_N	0.709	0.48
394_E	397_E	0.707	0.47
211_D	594_K	0.707	0.47
596_P	599_P	0.706	0.47
66_G	528_V	0.706	0.47
354_K	359_F	0.705	0.47
309_L	313_G	0.705	0.47
491_R	518_R	0.705	0.47
522_R	583_T	0.705	0.47
428_L	431_I	0.703	0.47
378_I	381_L	0.699	0.47
459_Y	492_F	0.697	0.46
198_L	551_F	0.696	0.46
49_V	54_N	0.692	0.46
481_R	544_L	0.692	0.46
335_Q	338_V	0.692	0.46
206_T	519_L	0.691	0.46
518_R	531_T	0.691	0.46
232_T	535_N	0.689	0.46
428_L	435_S	0.687	0.45
531_T	585_W	0.687	0.45
271_I	279_W	0.687	0.45
533_N	574_E	0.686	0.45
284_L	290_A	0.686	0.45
387_Q	392_S	0.684	0.45
206_T	210_K	0.683	0.45
229_L	547_T	0.683	0.45
466_F	536_D	0.682	0.45
344_R	349_K	0.682	0.45
30_G	199_G	0.681	0.45
289_S	294_T	0.681	0.45
356_N	361_E	0.680	0.45
278_S	286_G	0.678	0.45
199_G	490_H	0.678	0.45
340_P	344_R	0.676	0.44
530_A	551_F	0.674	0.44
68_F	566_T	0.673	0.44
285_D	290_A	0.673	0.44
578_V	592_K	0.669	0.44
276_S	294_T	0.668	0.44
233_G	552_R	0.668	0.44
278_S	281_K	0.666	0.43
193_F	542_I	0.665	0.43
266_G	278_S	0.665	0.43
191_L	514_A	0.665	0.43
214_A	599_P	0.665	0.43
487_D	510_A	0.665	0.43
235_Y	589_G	0.662	0.43
92_A	95_L	0.661	0.43
301_F	305_I	0.660	0.43
489_A	534_P	0.659	0.43
200_T	540_I	0.658	0.43
268_N	277_K	0.658	0.43
401_S	405_N	0.654	0.42
520_G	531_T	0.654	0.42
201_T	204_G	0.654	0.42
497_K	537_L	0.654	0.42
128_T	533_N	0.654	0.42
201_T	553_I	0.653	0.42
523_R	533_N	0.651	0.42
333_S	337_T	0.650	0.42
230_D	518_R	0.648	0.42
195_M	441_I	0.647	0.42
529_F	544_L	0.647	0.42
287_A	291_G	0.646	0.42
550_I	576_N	0.646	0.42
353_H	362_Q	0.644	0.41
516_M	574_E	0.644	0.41
384_L	430_K	0.643	0.41
80_V	444_L	0.643	0.41
341_F	348_V	0.642	0.41
387_Q	391_N	0.642	0.41
209_I	548_K	0.641	0.41
234_D	553_I	0.640	0.41
347_D	351_I	0.639	0.41
276_S	281_K	0.638	0.41
224_S	583_T	0.638	0.41
126_M	129_K	0.637	0.41
195_M	487_D	0.636	0.41
274_P	292_S	0.636	0.41
540_I	544_L	0.635	0.41
294_T	306_L	0.633	0.40
274_P	277_K	0.633	0.40
523_R	543_Q	0.633	0.40
126_M	142_D	0.632	0.40
200_T	551_F	0.630	0.40
383_D	388_F	0.630	0.40
65_I	187_S	0.629	0.40
173_G	576_N	0.627	0.40
358_Y	363_A	0.626	0.40
293_I	298_F	0.624	0.40
67_I	196_L	0.623	0.39
198_L	549_I	0.622	0.39
145_L	202_G	0.621	0.39
70_G	83_R	0.621	0.39
196_L	515_T	0.621	0.39
343_F	348_V	0.620	0.39
279_W	286_G	0.620	0.39
440_L	593_I	0.618	0.39
487_D	560_A	0.618	0.39
283_Y	410_L	0.618	0.39
307_N	311_N	0.617	0.39
343_F	356_N	0.617	0.39
291_G	295_K	0.617	0.39
580_Y	591_I	0.616	0.39
254_E	258_Q	0.615	0.39
350_T	434_D	0.614	0.39
429_G	433_K	0.613	0.39
225_K	440_L	0.612	0.38
256_F	265_K	0.612	0.38
409_G	456_I	0.611	0.38
210_K	531_T	0.609	0.38
203_A	454_Q	0.609	0.38
549_I	593_I	0.608	0.38
156_A	172_L	0.607	0.38
534_P	571_L	0.606	0.38
533_N	552_R	0.606	0.38
493_F	536_D	0.605	0.38
447_S	535_N	0.605	0.38
522_R	557_V	0.605	0.38
211_D	531_T	0.604	0.38
427_P	435_S	0.604	0.38
268_N	280_V	0.604	0.38
532_H	557_V	0.604	0.38
340_P	345_F	0.603	0.38
287_A	297_Y	0.600	0.37
49_V	57_Y	0.600	0.37
200_T	536_D	0.599	0.37
155_K	158_V	0.599	0.37
434_D	441_I	0.598	0.37
419_F	423_V	0.597	0.37
541_I	549_I	0.597	0.37
305_I	312_K	0.596	0.37
235_Y	490_H	0.595	0.37
140_G	199_G	0.593	0.37
442_F	462_L	0.592	0.37
57_Y	84_V	0.592	0.37
489_A	531_T	0.592	0.37
198_L	553_I	0.591	0.37
50_T	54_N	0.591	0.37
231_A	596_P	0.589	0.36
82_L	493_F	0.587	0.36
34_R	38_N	0.586	0.36
225_K	536_D	0.586	0.36
449_L	458_T	0.586	0.36
145_L	486_I	0.586	0.36
347_D	357_P	0.584	0.36
356_N	360_T	0.583	0.36
516_M	543_Q	0.583	0.36
540_I	552_R	0.582	0.36
382_D	386_D	0.581	0.36
292_S	295_K	0.581	0.36
397_E	400_K	0.581	0.36
272_I	279_W	0.581	0.36
335_Q	344_R	0.580	0.36
300_M	311_N	0.579	0.36
65_I	544_L	0.578	0.35
205_K	488_E	0.578	0.35
193_F	481_R	0.577	0.35
292_S	299_D	0.577	0.35
457_L	461_F	0.574	0.35
526_G	561_L	0.574	0.35
202_G	589_G	0.574	0.35
552_R	574_E	0.574	0.35
406_I	410_L	0.574	0.35
31_K	148_Q	0.573	0.35
529_F	543_Q	0.573	0.35
338_V	347_D	0.572	0.35
277_K	285_D	0.571	0.35
516_M	533_N	0.570	0.35
263_I	273_Y	0.570	0.35
334_S	341_F	0.570	0.35
282_K	287_A	0.569	0.35
286_G	289_S	0.569	0.35
311_N	350_T	0.568	0.35
302_V	310_N	0.568	0.35
163_L	182_V	0.564	0.34
225_K	552_R	0.563	0.34
142_D	159_I	0.562	0.34
196_L	489_A	0.562	0.34
284_L	294_T	0.562	0.34
348_V	357_P	0.561	0.34
522_R	529_F	0.558	0.34
200_T	513_I	0.557	0.34
232_T	544_L	0.557	0.34
202_G	557_V	0.556	0.34
186_T	220_N	0.556	0.34
234_D	519_L	0.556	0.34
342_Y	356_N	0.556	0.34
243_D	457_L	0.555	0.33
60_P	84_V	0.555	0.33
519_L	554_K	0.554	0.33
257_T	260_Y	0.554	0.33
396_V	399_H	0.553	0.33
514_A	533_N	0.552	0.33
192_N	551_F	0.552	0.33
227_F	494_P	0.551	0.33
286_G	293_I	0.549	0.33
540_I	557_V	0.549	0.33
192_N	227_F	0.549	0.33
199_G	487_D	0.549	0.33
353_H	358_Y	0.548	0.33
297_Y	303_K	0.547	0.33
213_I	312_K	0.547	0.33
417_Q	427_P	0.546	0.33
29_V	34_R	0.545	0.33
201_T	235_Y	0.545	0.33
158_V	542_I	0.545	0.33
263_I	302_V	0.545	0.33
128_T	136_S	0.545	0.33
151_V	485_I	0.544	0.32
213_I	485_I	0.544	0.32
160_E	404_E	0.544	0.32
333_S	346_K	0.544	0.32
123_R	411_Y	0.544	0.32
142_D	199_G	0.543	0.32
232_T	584_P	0.542	0.32
308_H	312_K	0.541	0.32
450_D	463_D	0.539	0.32
335_Q	342_Y	0.537	0.32
458_T	466_F	0.537	0.32
292_S	409_G	0.536	0.32
234_D	532_H	0.535	0.32
196_L	519_L	0.534	0.32
203_A	551_F	0.534	0.32
492_F	545_A	0.534	0.32
200_T	523_R	0.533	0.32
524_K	557_V	0.533	0.32
111_D	186_T	0.533	0.32
396_V	402_T	0.533	0.32
517_M	522_R	0.533	0.32
523_R	532_H	0.532	0.31
378_I	386_D	0.531	0.31
265_K	269_V	0.531	0.31
198_L	552_R	0.530	0.31
534_P	583_T	0.530	0.31
393_L	396_V	0.529	0.31
468_F	523_R	0.529	0.31
466_F	520_G	0.529	0.31
353_H	359_F	0.529	0.31
235_Y	487_D	0.529	0.31
388_F	410_L	0.529	0.31
207_S	211_D	0.528	0.31
249_V	363_A	0.528	0.31
522_R	533_N	0.528	0.31
410_L	484_I	0.528	0.31
577_G	594_K	0.528	0.31
509_V	557_V	0.527	0.31
30_G	57_Y	0.527	0.31
193_F	534_P	0.526	0.31
140_G	144_I	0.525	0.31
336_V	345_F	0.525	0.31
196_L	230_D	0.525	0.31
519_L	540_I	0.523	0.31
296_M	302_V	0.523	0.31
490_H	531_T	0.523	0.31
268_N	442_F	0.523	0.31
531_T	546_N	0.521	0.31
77_L	461_F	0.521	0.31
267_I	276_S	0.520	0.30
344_R	350_T	0.520	0.30
340_P	349_K	0.519	0.30
140_G	554_K	0.518	0.30
229_L	580_Y	0.518	0.30
342_Y	345_F	0.517	0.30
352_L	356_N	0.517	0.30
524_K	533_N	0.516	0.30
522_R	531_T	0.516	0.30
335_Q	347_D	0.515	0.30
339_Y	345_F	0.515	0.30
493_F	545_A	0.513	0.30
355_L	359_F	0.513	0.30
144_I	491_R	0.513	0.30
567_E	589_G	0.512	0.30
299_D	304_P	0.512	0.30
490_H	583_T	0.511	0.30
273_Y	276_S	0.511	0.30
401_S	404_E	0.510	0.30
357_P	430_K	0.510	0.30
136_S	492_F	0.510	0.30
467_E	471_R	0.509	0.30
478_V	581_L	0.508	0.30
36_I	41_D	0.507	0.29
339_Y	346_K	0.506	0.29
285_D	302_V	0.506	0.29
409_G	536_D	0.505	0.29
63_G	84_V	0.503	0.29
453_S	484_I	0.501	0.29
466_F	535_N	0.501	0.29
230_D	519_L	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4d2iA	3	0.7406	100	0.507	Contact Map
4ag6A	2	0.5862	100	0.695	Contact Map
1e9rA	3	0.6305	100	0.746	Contact Map
2iusA	1	0.5895	99.7	0.855	Contact Map
2iutA	2	0.6256	99.2	0.891	Contact Map
4lyaA	1	0.4269	99.2	0.893	Contact Map
4nh0A	1	0.4122	99.1	0.898	Contact Map
2r2aA	1	0.2972	98.1	0.925	Contact Map
4kfuA	1	0.3333	97.4	0.936	Contact Map
3qf7A	2	0.514	96.6	0.943	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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